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TitleAlternate modes of binding in two crystal structures of alkaline phosphatase-inhibitor complexes.
Journal, issue, pagesProtein Sci., Vol. 9, Page 907-915, Year 2000
Publish dateApr 24, 2000 (structure data deposition date)
AuthorsHoltz, K.M. / Stec, B. / Myers, J.K. / Antonelli, S.M. / Widlanski, T.S. / Kantrowitz, E.R.
External linksPubMed:10850800
MethodsX-ray diffraction
Resolution2 - 2.2 Å
Structure data

PDB-1ew8:
ALKALINE PHOSPHATASE (E.C. 3.1.3.1) COMPLEX WITH PHOSPHONOACETIC ACID
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1ew9:
ALKALINE PHOSPHATASE (E.C. 3.1.3.1) COMPLEX WITH MERCAPTOMETHYL PHOSPHONATE
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

ChemComp-PAE:
PHOSPHONOACETIC ACID

ChemComp-HOH:
WATER

ChemComp-MMQ:
MERCAPTOMETHYL PHOSPHONATE

Source
  • escherichia coli (E. coli)
KeywordsHYDROLASE / enzyme-inhibitor complex

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