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Structure paper

TitleCrystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 101, Page 413-424, Year 2000
Publish dateApr 19, 2000 (structure data deposition date)
AuthorsPlotnikov, A.N. / Hubbard, S.R. / Schlessinger, J. / Mohammadi, M.
External linksCell(Cambridge,Mass. ) / PubMed:10830168
MethodsX-ray diffraction
Resolution2.2 - 2.8 Å
Structure data

PDB-1ev2:
CRYSTAL STRUCTURE OF FGF2 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 2 (FGFR2)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1evt:
CRYSTAL STRUCTURE OF FGF1 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 1 (FGFR1)
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGROWTH FACTOR/GROWTH FACTOR RECEPTOR / IMMUNOGLOBULIN (IG)LIKE DOMAINS BELONGING TO THE I-SET SUBGROUP WITHIN IG-LIKE DOMAINS / B-TREFOIL FOLD / GROWTH FACTOR-GROWTH FACTOR RECEPTOR COMPLEX / IMMUNOGLOBULIN (IG) LIKE DOMAINS BELONGING TO THE I-SET SUBGROUP WITHIN IG-LIKE DOMAINS

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