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Structure paper

TitleThe Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions.
Journal, issue, pagesJ. Biol. Chem., Vol. 275, Page 15377-, Year 2000
Publish dateFeb 28, 2000 (structure data deposition date)
AuthorsHuntington, J.A. / Mccoy, A.J. / Belzar, K.J. / Pei, X.Y. / Gettins, P.G.W. / Carrell, R.W.
External linksJ. Biol. Chem. / PubMed:10809774
MethodsX-ray diffraction
Resolution2.8 - 2.85 Å
Structure data

PDB-1dzg:
N135Q-S380C-ANTITHROMBIN-III
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-1dzh:
P14-FLUORESCEIN-N135Q-S380C-ANTITHROMBIN-III
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsBLOOD CLOTTING / SERPIN

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