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Structure paper

TitleMapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc.
Journal, issue, pagesJ. Immunol., Vol. 164, Page 4178-4184, Year 2000
Publish dateMar 14, 2002 (structure data deposition date)
AuthorsIdusogie, E.E. / Presta, L.G. / Gazzano-Santoro, H. / Totpal, K. / Wong, P.Y. / Ultsch, M. / Meng, Y.G. / Mulkerrin, M.G.
External linksPubMed:10754313
MethodsX-ray diffraction
Resolution1.65 Å
Structure data

PDB-1l6x:
FC FRAGMENT OF RITUXIMAB BOUND TO A MINIMIZED VERSION OF THE B-DOMAIN FROM PROTEIN A CALLED Z34C
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / IgG1 fc / protein A / fc complex / b-domain

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