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TitleInhibitor Binding Induces Active Site Stabilisation of the Hcv Ns3 Protein Serine Protease Domain
Journal, issue, pagesEmbo J., Vol. 19, Page 1195-, Year 2000
Publish dateJan 17, 2000 (structure data deposition date)
AuthorsBarbato, G. / Cicero, D.O. / Cordier, F. / Narjes, F. / Gerlach, B. / Sambucini, S. / Grzesiek, S. / Matassa, V.G. / Defrancesco, R. / Bazzo, R.
External linksEmbo J. / PubMed:10716920
MethodsNMR (solution)
Structure data

PDB-1dxw:
structure of hetero complex of non structural protein (NS) of hepatitis C virus (HCV) and synthetic peptidic compound
Method: SOLUTION NMR

Chemicals

ChemComp-2ZF:
N-(tert-butoxycarbonyl)-L-alpha-glutamyl-N-[(1R)-1-(carboxycarbonyl)-3,3-difluoropropyl]-L-leucinamide

ChemComp-ZN:
Unknown entry

Source
  • hepatitis c virus
KeywordsHYDROLASE/HYDROLASE INHIBITOR / NON STRUCTURAL PROTEIN / HEPATITIS C VIRUS / SERINE PROTEASE / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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