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Structure paper

TitleStructural basis for substrate specificity of protein-tyrosine phosphatase SHP-1.
Journal, issue, pagesJ. Biol. Chem., Vol. 275, Page 4066-4071, Year 2000
Publish dateAug 31, 2000 (structure data deposition date)
AuthorsYang, J. / Cheng, Z. / Niu, T. / Liang, X. / Zhao, Z.J. / Zhou, G.W.
External linksJ. Biol. Chem. / PubMed:10660565
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1fpr:
CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN THE CATALYTIC DOMAIN OF SHP-1 AND AN IN VITRO PEPTIDE SUBSTRATE PY469 DERIVED FROM SHPS-1.
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / protein tyrosine phosphatase / substrate specificity / residue shift

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