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TitleAntibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
Journal, issue, pagesJ. Mol. Biol., Vol. 293, Page 855-863, Year 1999
Publish dateAug 14, 1999 (structure data deposition date)
AuthorsKanyo, Z.F. / Pan, K.M. / Williamson, R.A. / Burton, D.R. / Prusiner, S.B. / Fletterick, R.J. / Cohen, F.E.
External linksJ. Mol. Biol. / PubMed:10543972
MethodsX-ray diffraction
Resolution2 - 2.9 Å
Structure data

PDB-1cr9:
CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1cu4:
CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 IN COMPLEX WITH ITS PEPTIDE EPITOPE
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / anti-prion antibody / Fab 3F4 / IMMUNOGLOBULIN FOLD

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