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TitleCrystal structure of human DT-diaphorase: a model for interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954).
Journal, issue, pagesJ. Med. Chem., Vol. 42, Page 4325-4330, Year 1999
Publish dateApr 20, 1999 (structure data deposition date)
AuthorsSkelly, J.V. / Sanderson, M.R. / Suter, D.A. / Baumann, U. / Read, M.A. / Gregory, D.S. / Bennett, M. / Hobbs, S.M. / Neidle, S.
External linksJ. Med. Chem. / PubMed:10543876
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1qbg:
CRYSTAL STRUCTURE OF HUMAN DT-DIAPHORASE (NAD(P)H OXIDOREDUCTASE)
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / QUINONE / FAD / DT-DIAPHORASE

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