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TitleThe three-dimensional structure of caspase-8: an initiator enzyme in apoptosis.
Journal, issue, pagesStructure Fold. Des., Vol. 7, Page 1125-1133, Year 1999
Publish dateJul 10, 1999 (structure data deposition date)
AuthorsBlanchard, H. / Kodandapani, L. / Mittl, P.R. / Marco, S.D. / Krebs, J.F. / Wu, J.C. / Tomaselli, K.J. / Grutter, M.G.
External linksStructure Fold. Des. / PubMed:10508784
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-1qdu:
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-8 WITH THE TRIPEPTIDE KETONE INHIBITOR ZEVD-DCBMK
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / APOPTOSIS / CYSTEINE PROTEASE / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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