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TitleCrystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase.
Journal, issue, pagesJ. Biol. Chem., Vol. 274, Page 21276-21284, Year 1999
Publish dateJan 10, 1999 (structure data deposition date)
AuthorsLi, H. / Raman, C.S. / Glaser, C.B. / Blasko, E. / Young, T.A. / Parkinson, J.F. / Whitlow, M. / Poulos, T.L.
External linksJ. Biol. Chem. / PubMed:10409685
MethodsX-ray diffraction
Resolution2.55 - 3 Å
Structure data

PDB-1nsi:
HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE, ZN-BOUND, L-ARG COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-2nsi:
HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE, ZN-FREE, SEITU COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-ZN:
Unknown entry

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-H4B:
5,6,7,8-TETRAHYDROBIOPTERIN / neurotransmitter*YM

ChemComp-ARG:
ARGININE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-ITU:
ETHYLISOTHIOUREA

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / NITRIC OXIDE SYNTHASE / HEME PROTEIN / TETRAHYDROBIOPTERIN

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