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TitleStructure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate.
Journal, issue, pagesStructure Fold. Des., Vol. 7, Page 449-460, Year 1999
Publish dateJan 12, 1999 (structure data deposition date)
AuthorsBaraldi, E. / Djinovic Carugo, K. / Hyvonen, M. / Surdo, P.L. / Riley, A.M. / Potter, B.V. / O'Brien, R. / Ladbury, J.E. / Saraste, M.
External linksStructure Fold. Des. / PubMed:10196129
MethodsX-ray diffraction
Resolution2.1 - 2.4 Å
Structure data

PDB-1b55:
PH DOMAIN FROM BRUTON'S TYROSINE KINASE IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1bwn:
PH DOMAIN AND BTK MOTIF FROM BRUTON'S TYROSINE KINASE MUTANT E41K IN COMPLEX WITH INS(1,3,4,5)P4
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-4IP:
INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PH DOMAIN / BTK MOTIF / ZINC BINDING / X-LINKED AGAMMAGLOBULINEMIA / TYROSINE-PROTEIN KINASE / INOSITOL 1 / 3 / 4 / 5-TETRAKISPHOSPHATE / INOSITOL-(1 / 5)-TETRAKISPHOSPHATE

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