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Structure paper

TitleDe Novo Design of Integrin alpha5beta1 Modulating Proteins for Regenerative Medicine
Journal, issue, pagesTo Be Published
Publish dateJul 9, 2024 (structure data deposition date)
AuthorsWang X / Guillem-Marti J / Kumar S / Lee DS / Cabrerizo-Aguado D / Werther R / Estrada Alamo KA / Zhao YT / Nguyen A / Kopyeva I ...Wang X / Guillem-Marti J / Kumar S / Lee DS / Cabrerizo-Aguado D / Werther R / Estrada Alamo KA / Zhao YT / Nguyen A / Kopyeva I / Huang B / Li J / Hao Y / Li X / Brizuela-Velasco A / Murray AN / Gerben S / Roy A / DeForest CA / Springer T / Ruohola-Baker H / Cooper JA / Campbell MG / Maria Manero J / Ginebra M / Baker D
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.19 Å
Structure data

EMDB-45655, PDB-9ckv:
Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin
Method: EM (single particle) / Resolution: 3.19 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-MN:
Unknown entry

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsSIGNALING PROTEIN / a5B1 / de novo / tissue regeneration / extracellular matrix protein

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