[English] 日本語
EMN Papers
- Database of articles cited by 3DEM data entries -

+
Search query

Keywords
Author
Journal
IF

-
Structure paper

TitleStructural and Functional Insights into Human Re-initiation Complexes.
Journal, issue, pagesMol. Cell, Vol. 67, Issue 3, Page 447-456.e7, Year 2017
Publish dateAug 3, 2017
AuthorsMelanie Weisser / Tanja Schäfer / Marc Leibundgut / Daniel Böhringer / Christopher Herbert Stanley Aylett / Nenad Ban
External linksPubMed:28732596 / Publisher's page
KeywordsTRANSLATION / translation re-initiation complex / translation initiation factor / RNA binding protein / small ribosomal subunit / Binding Sites / Cell Cycle Proteins / Cryoelectron Microscopy / Crystallography, X-Ray / DENR protein, human / Eukaryotic Initiation Factor-2 / Eukaryotic Initiation Factors / HEK293 Cells / Humans / MCTS1 protein, human / Molecular Docking Simulation / Multiprotein Complexes / Mutation / Nucleic Acid Conformation / Oncogene Proteins / Protein Binding / Protein Conformation / RNA, Messenger / RNA, Transfer / Ribosome Subunits, Small, Eukaryotic / Structure-Activity Relationship / Transcription Initiation Site / Transcription Initiation, Genetic / Transfection / eIF2D protein, human / eukaryotic translation initiation factor
MethodsX-ray diffraction / EM (single particle)
Resolution1.8 - 4.2 A
Structure data

PDB-5oa9:
Human translation re-initiation complex containing eIF2D

EMDB-3770:
Human 40S-eIF2D-re-initiation complex

PDB-5oa3:
Human 40S-eIF2D-re-initiation complex

Chemicals

ChemComp-HOH:
WATERWater

ChemComp-ZN:
ZINC IONZinc

Source
  • homo sapiens (human)
  • Homo sapiens (human)
  • Hepatitis C virus
  • Saccharomyces cerevisiae (baker's yeast)
  • saccharomyces cerevisiae (baker's yeast)
  • hepatitis c virus

+
About EMN Papers

-
News

-
Feb 20, 2018. PDBj/BINDS workshop in Osaka University

PDBj/BINDS workshop in Osaka University

    -
    Oct 4, 2017. Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

    Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

    • Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
    • Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
    • Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.

    External links: The 2017 Nobel Prize in Chemistry - Press Release

    +
    Jul 12, 2017. Major update of PDB

    Major update of PDB

    • wwPDB released updated PDB data conforming to the new PDBx/mmCIF dictionary. This is a major update changing the version number from 4 to 5, and with Remediation, in which all the entries are updated. See below links for details.
    • In this update, many items about electron microscopy experimental information are reorganized (e.g. em_software). Now, EM Navigator and Yorodumi are based on the updated data.

    External links: wwPDB Remediation / Enriched Model Files Conforming to OneDep Data Standards Now Available in the PDB FTP Archive

    +
    Jun 16, 2017. Omokage search with filter

    Omokage search with filter

    • Result of Omokage search can be filtered by keywords and the database types

    Related info.: Omokage search

    +
    Sep 15, 2016. EM Navigator & Yorodumi renewed

    EM Navigator & Yorodumi renewed

    • New versions of EM Navigator and Yorodumi started

    Related info.: Changes in new EM Navigator and Yorodumi

    Read more

    -
    EMN Papers

    Database of articles cited by 3DEM data entries

    • Database of articles cited by 3DEM data entries in EMDB and PDB
    • Using PubMed data

    Related info.: EMDB / PDB / Q: What is the data source of EM Navigator? / EM Navigator / Yorodumi Papers / Changes in new EM Navigator and Yorodumi

    Read more