Entry Database : PDB / ID : 4tmu Structure visualization Downloads & linksTitle Crystal structure of RecQ catalytic core from C. sakazakii bound to DNA ComponentsDNA (29-MER) RecQ RecQ helicase DetailsKeywords Hydrolase/DNA / RecQ / helicase / Winged helix / ATP binding / Hydrolase-DNA complexFunction / homology Function and homology informationFunction Domain/homology Component
3'-5' DNA helicase activity / SOS response / DNA recombination / DNA helicase / DNA replication / DNA repair / DNA binding / ATP binding / metal ion binding Similarity search - Function DNA helicase, ATP-dependent, RecQ type, bacterial / RQC domain / RQC / RQC domain / ATP-dependent DNA helicase RecQ, zinc-binding domain / RecQ zinc-binding / DNA helicase, ATP-dependent, RecQ type / Helicase and RNase D C-terminal / HRDC domain / HRDC domain ... DNA helicase, ATP-dependent, RecQ type, bacterial / RQC domain / RQC / RQC domain / ATP-dependent DNA helicase RecQ, zinc-binding domain / RecQ zinc-binding / DNA helicase, ATP-dependent, RecQ type / Helicase and RNase D C-terminal / HRDC domain / HRDC domain / HRDC domain profile. / HRDC domain superfamily / HRDC-like superfamily / DEAD/DEAH box helicase / DEAD/DEAH box helicase domain / Helicase conserved C-terminal domain / helicase superfamily c-terminal domain / Superfamilies 1 and 2 helicase C-terminal domain profile. / Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. / DEAD-like helicases superfamily / Helicase, C-terminal / Helicase superfamily 1/2, ATP-binding domain / P-loop containing nucleotide triphosphate hydrolases / Winged helix-like DNA-binding domain superfamily / P-loop containing nucleoside triphosphate hydrolase / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homologyBiological species Cronobacter sakazakii (bacteria)synthetic construct (others) Method X-RAY DIFFRACTION / SYNCHROTRON / Resolution : 2.4 Å DetailsAuthors Manthei, K.A. / Keck, J.L. Funding support United States, 3items Details Hide detailsOrganization Grant number Country National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) P41GM103399 United States Department of Energy (DOE, United States) DE-AC02-06CH11357 United States National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) GM098885 United States
CitationJournal : Proc.Natl.Acad.Sci.USA / Year : 2015Title : Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases.Authors : Manthei, K.A. / Hill, M.C. / Burke, J.E. / Butcher, S.E. / Keck, J.L. History Deposition Jun 2, 2014 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Mar 11, 2015 Provider : repository / Type : Initial releaseRevision 1.1 Mar 25, 2015 Group : Database referencesRevision 1.2 Apr 15, 2015 Group : Database referencesRevision 1.3 Apr 22, 2015 Group : Database referencesRevision 1.4 Jan 1, 2020 Group : Author supporting evidence / Database references ... Author supporting evidence / Database references / Derived calculations / Other / Source and taxonomy Category : citation / entity_src_gen ... citation / entity_src_gen / pdbx_audit_support / pdbx_database_status / pdbx_entity_src_syn / pdbx_struct_oper_list Item : _citation.journal_id_CSD / _entity_src_gen.pdbx_alt_source_flag ... _citation.journal_id_CSD / _entity_src_gen.pdbx_alt_source_flag / _pdbx_database_status.pdb_format_compatible / _pdbx_entity_src_syn.pdbx_alt_source_flag / _pdbx_struct_oper_list.symmetry_operation Revision 1.5 Dec 27, 2023 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / refine_hist Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _refine_hist.number_atoms_solvent / _refine_hist.pdbx_number_atoms_ligand / _refine_hist.pdbx_number_atoms_nucleic_acid / _refine_hist.pdbx_number_atoms_protein
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