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- EMDB-12631: Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-s... -

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Basic information

Entry
Database: EMDB / ID: EMD-12631
TitleMammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S.
Map data
Sample
  • Complex: Mammalian pre-termination 80S ribosome with Hybrid-P/E and -A/P site tRNAs bound by Blasticidin S.
    • RNA: x 6 types
    • Protein or peptide: x 79 types
  • RNA: x 1 types
  • Ligand: x 3 types
Function / homology
Function and homology information


L13a-mediated translational silencing of Ceruloplasmin expression / SRP-dependent cotranslational protein targeting to membrane / Major pathway of rRNA processing in the nucleolus and cytosol / Formation of a pool of free 40S subunits / GTP hydrolysis and joining of the 60S ribosomal subunit / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / Translation initiation complex formation / Formation of the ternary complex, and subsequently, the 43S complex / Ribosomal scanning and start codon recognition ...L13a-mediated translational silencing of Ceruloplasmin expression / SRP-dependent cotranslational protein targeting to membrane / Major pathway of rRNA processing in the nucleolus and cytosol / Formation of a pool of free 40S subunits / GTP hydrolysis and joining of the 60S ribosomal subunit / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / Translation initiation complex formation / Formation of the ternary complex, and subsequently, the 43S complex / Ribosomal scanning and start codon recognition / Major pathway of rRNA processing in the nucleolus and cytosol / GTP hydrolysis and joining of the 60S ribosomal subunit / L13a-mediated translational silencing of Ceruloplasmin expression / SRP-dependent cotranslational protein targeting to membrane / Formation of a pool of free 40S subunits / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / rough endoplasmic reticulum / DNA-(apurinic or apyrimidinic site) lyase / cytosolic ribosome / cytosolic small ribosomal subunit / small ribosomal subunit / cytoplasmic translation / 5S rRNA binding / cytosolic large ribosomal subunit / rRNA binding / ribosome / structural constituent of ribosome / ribonucleoprotein complex / translation / nucleolus / RNA binding / cytoplasm
Similarity search - Function
: / metallochaperone-like domain / TRASH domain / Ribosomal protein S21e, conserved site / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein S26e signature. / Ribosomal protein S17e, conserved site / Ribosomal protein S21e ...: / metallochaperone-like domain / TRASH domain / Ribosomal protein S21e, conserved site / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein S26e signature. / Ribosomal protein S17e, conserved site / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein S21e signature. / Ribosomal protein S12e signature. / Ribosomal protein S17e / Ribosomal protein S17e-like superfamily / Ribosomal protein L24e, conserved site / Ribosomal protein S6, eukaryotic / Ribosomal S17 / Ribosomal protein S19e signature. / 40S Ribosomal protein S10 / Ribosomal protein S6/S6e/A/B/2, conserved site / Plectin/S10, N-terminal / Plectin/S10 domain / Ribosomal protein S6e / Ribosomal protein S6e / Ribosomal protein S4/S9, eukaryotic/archaeal / Ribosomal protein L19, eukaryotic / Ribosomal protein L1 signature. / Ribosomal protein S17e signature. / Ribosomal protein L10e signature. / Ribosomal protein L27e signature. / Ribosomal protein S7e signature. / 60S ribosomal protein L18a/ L20, eukaryotes / Ribosomal protein L19/L19e conserved site / Ribosomal protein S6e / Ribosomal protein S3Ae signature. / Ribosomal protein S27e signature. / Ribosomal protein L39e, conserved site / 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a / Ribosomal protein L19e signature. / Ribosomal protein L24e signature. / Ribosomal protein S8e signature. / Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A / Ribosomal protein L34e signature. / Ribosomal protein L6e signature. / Ribosomal protein L30e signature 1. / Ribosomal protein L30e signature 2. / 60S ribosomal protein L19 / Ribosomal protein L39e signature. / Ribosomal protein L39e / Ribosomal protein L24e-related / Ribosomal protein L39e domain superfamily / Ribosomal protein L24e/L24 superfamily / Ribosomal protein S6e signature. / Ribosomal protein L35Ae signature. / Ribosomal_L19e / Ribosomal protein L19/L19e / Ribosomal protein L19/L19e, domain 1 / Ribosomal protein L19/L19e superfamily / Ribosomal L39 protein / Ribosomal protein L19e / Ribosomal protein S28e signature. / Ribosomal protein L24e / Ribosomal protein L31e signature. / Ribosomal protein L5 eukaryotic/L18 archaeal / Ribosomal large subunit proteins 60S L5, and 50S L18 / Ribosomal protein L32e signature. / Ribosomal protein L6 signature 2. / Ribosomal protein L1e signature. / Ribosomal protein L15e signature. / Ribosomal protein L21e signature. / Ribosomal protein L37e signature. / Ribosomal protein S2 signature 2. / Ubiquitin domain signature. / Ribosomal protein L23 signature. / Ribosomal protein L30 signature. / Ribosomal protein S3 signature. / Ribosomal protein S14 signature. / Ribosomal protein S2 signature 1. / Ribosomal protein L5 signature. / Ribosomal protein L29 signature. / Ribosomal protein S4/S9 N-terminal domain / Ribosomal protein S4/S9, N-terminal / Ribosomal protein S4, conserved site / Type-2 KH domain profile. / Ribosomal protein S4/S9 N-terminal domain / Ribosomal protein S4/S9 / Ribosomal protein S19 signature. / Ribosomal protein S7 signature. / Ribosomal protein S17 signature. / S4 RNA-binding domain / RNA-binding S4 domain / Ribosomal protein S13 signature. / RNA-binding S4 domain superfamily / Ribosomal protein S13 family profile. / S4 domain
Similarity search - Domain/homology
Large ribosomal subunit protein eL24 / Small ribosomal subunit protein eS32 / Small ribosomal subunit protein uS4 / Large ribosomal subunit protein eL20 / 40S ribosomal protein S10 / 40S ribosomal protein S6 / Large ribosomal subunit protein uL16 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Small ribosomal subunit protein eS12 ...Large ribosomal subunit protein eL24 / Small ribosomal subunit protein eS32 / Small ribosomal subunit protein uS4 / Large ribosomal subunit protein eL20 / 40S ribosomal protein S10 / 40S ribosomal protein S6 / Large ribosomal subunit protein uL16 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Small ribosomal subunit protein eS12 / Large ribosomal subunit protein eL29 / Small ribosomal subunit protein uS9 / Large ribosomal subunit protein eL31 / Large ribosomal subunit protein eL21 / Large ribosomal subunit protein uL29 / Small ribosomal subunit protein RACK1 / Ubiquitin-ribosomal protein eS31 fusion protein / Large ribosomal subunit protein eL6 / Large ribosomal subunit protein uL1 / Small ribosomal subunit protein uS15 / Large ribosomal subunit protein uL10 / Large ribosomal subunit protein uL24 / Small ribosomal subunit protein eS1 / Large ribosomal subunit protein eL8 / Large ribosomal subunit protein uL30 / Small ribosomal subunit protein eS7 / Large ribosomal subunit protein uL4 / Large ribosomal subunit protein uL6 / Large ribosomal subunit protein uL18 / Large ribosomal subunit protein eL14 / Small ribosomal subunit protein uS12 / Large ribosomal subunit protein eL15 / Small ribosomal subunit protein uS11 / Large ribosomal subunit protein uL14 / Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein / Large ribosomal subunit protein eL30 / Small ribosomal subunit protein uS7 / Small ribosomal subunit protein eS28 / Small ribosomal subunit protein eS8 / Large ribosomal subunit protein eL13 / Large ribosomal subunit protein uL3 / Small ribosomal subunit protein uS2 / Small ribosomal subunit protein eS19 / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS13 / Small ribosomal subunit protein uS17 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein uL5 / Large ribosomal subunit protein eL32 / Large ribosomal subunit protein eL27 / Small ribosomal subunit protein eS27 / Small ribosomal subunit protein uS19 / Large ribosomal subunit protein eL28 / Small ribosomal subunit protein uS14 / Large ribosomal subunit protein eL34 / Small ribosomal subunit protein eS21 / Large ribosomal subunit protein eL19 / 40S ribosomal protein S17 / 40S ribosomal protein S26 / Large ribosomal subunit protein eL37
Similarity search - Component
Biological speciesOryctolagus cuniculus (rabbit) / Rabbit (rabbit) / Bovine (cattle)
Methodsingle particle reconstruction / cryo EM / Resolution: 3.8 Å
AuthorsPowers KT / Yadav SKN / Bufton JC / Schaffitzel C
Funding support United Kingdom, 1 items
OrganizationGrant numberCountry
Wellcome Trust210701/Z/18/Z United Kingdom
CitationJournal: Nucleic Acids Res / Year: 2021
Title: Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Authors: Kyle T Powers / Flint Stevenson-Jones / Sathish K N Yadav / Beate Amthor / Joshua C Bufton / Ufuk Borucu / Dakang Shen / Jonas P Becker / Daria Lavysh / Matthias W Hentze / Andreas E Kulozik ...Authors: Kyle T Powers / Flint Stevenson-Jones / Sathish K N Yadav / Beate Amthor / Joshua C Bufton / Ufuk Borucu / Dakang Shen / Jonas P Becker / Daria Lavysh / Matthias W Hentze / Andreas E Kulozik / Gabriele Neu-Yilik / Christiane Schaffitzel /
Abstract: Deciphering translation is of paramount importance for the understanding of many diseases, and antibiotics played a pivotal role in this endeavour. Blasticidin S (BlaS) targets translation by binding ...Deciphering translation is of paramount importance for the understanding of many diseases, and antibiotics played a pivotal role in this endeavour. Blasticidin S (BlaS) targets translation by binding to the peptidyl transferase center of the large ribosomal subunit. Using biochemical, structural and cellular approaches, we show here that BlaS inhibits both translation elongation and termination in Mammalia. Bound to mammalian terminating ribosomes, BlaS distorts the 3'CCA tail of the P-site tRNA to a larger extent than previously reported for bacterial ribosomes, thus delaying both, peptide bond formation and peptidyl-tRNA hydrolysis. While BlaS does not inhibit stop codon recognition by the eukaryotic release factor 1 (eRF1), it interferes with eRF1's accommodation into the peptidyl transferase center and subsequent peptide release. In human cells, BlaS inhibits nonsense-mediated mRNA decay and, at subinhibitory concentrations, modulates translation dynamics at premature termination codons leading to enhanced protein production.
History
DepositionMar 16, 2021-
Header (metadata) releaseJul 7, 2021-
Map releaseJul 7, 2021-
UpdateJan 11, 2023-
Current statusJan 11, 2023Processing site: PDBe / Status: Released

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Structure visualization

Movie
  • Surface view with section colored by density value
  • Surface level: 0.016
  • Imaged by UCSF Chimera
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  • Surface view colored by height
  • Surface level: 0.016
  • Imaged by UCSF Chimera
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  • Surface view with fitted model
  • Atomic models: PDB-7nwg
  • Surface level: 0.025
  • Imaged by UCSF Chimera
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Movie viewer
Structure viewerEM map:
SurfViewMolmilJmol/JSmol
Supplemental images

emd_12631.png

Downloads & links

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Map

FileDownload / File: emd_12631.map.gz / Format: CCP4 / Size: 103 MB / Type: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
Voxel sizeX=Y=Z: 1.35 Å
Density
Contour LevelBy AUTHOR: 0.014 / Movie #1: 0.016
Minimum - Maximum-0.1072583 - 0.17151321
Average (Standard dev.)0.0010414778 (±0.00778793)
SymmetrySpace group: 1
Details

EMDB XML:

Map geometry
Axis orderXYZ
Origin000
Dimensions300300300
Spacing300300300
CellA=B=C: 405.0 Å
α=β=γ: 90.0 °

CCP4 map header:

modeImage stored as Reals
Å/pix. X/Y/Z1.351.351.35
M x/y/z300300300
origin x/y/z0.0000.0000.000
length x/y/z405.000405.000405.000
α/β/γ90.00090.00090.000
MAP C/R/S123
start NC/NR/NS000
NC/NR/NS300300300
D min/max/mean-0.1070.1720.001

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Supplemental data

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Mask #1

Fileemd_12631_msk_1.map
Projections & Slices
AxesZYX

Projections

Slices (1/2)
Density Histograms

Histogram

Histogram (log scale)

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Half map: #2

Fileemd_12631_half_map_1.map
Projections & Slices
AxesZYX

Projections

Slices (1/2)
Density Histograms

Histogram

Histogram (log scale)

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Half map: #1

Fileemd_12631_half_map_2.map
Projections & Slices
AxesZYX

Projections

Slices (1/2)
Density Histograms

Histogram

Histogram (log scale)

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Sample components

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Entire : Mammalian pre-termination 80S ribosome with Hybrid-P/E and -A/P s...

EntireName: Mammalian pre-termination 80S ribosome with Hybrid-P/E and -A/P site tRNAs bound by Blasticidin S.
Components
  • Complex: Mammalian pre-termination 80S ribosome with Hybrid-P/E and -A/P site tRNAs bound by Blasticidin S.
    • RNA: 28S Ribosomal RNA
    • RNA: 5S Ribosomal RNA
    • RNA: 5.8S Ribosomal RNA
    • RNA: 18S Ribosomal RNA
    • Protein or peptide: 40S ribosomal protein SA
    • Protein or peptide: 40S ribosomal protein S3a
    • Protein or peptide: 40S ribosomal protein S2
    • Protein or peptide: 40S ribosomal protein S3
    • Protein or peptide: S4
    • Protein or peptide: Ribosomal protein S5
    • Protein or peptide: 40S ribosomal protein S6
    • Protein or peptide: ribosomal protein eS7
    • Protein or peptide: 40S ribosomal protein S8
    • Protein or peptide: 40S ribosomal protein S9
    • Protein or peptide: 40S ribosomal protein S10
    • Protein or peptide: 40S ribosomal protein S11
    • Protein or peptide: 40S ribosomal protein S12
    • Protein or peptide: ribosomal protein uS15
    • Protein or peptide: uS11
    • Protein or peptide: 40S ribosomal protein uS19
    • Protein or peptide: Ribosomal protein S16
    • Protein or peptide: 40S ribosomal protein S17
    • Protein or peptide: 40S ribosomal protein uS13
    • Protein or peptide: S19
    • Protein or peptide: 40S ribosomal protein S20
    • Protein or peptide: 40S ribosomal protein S21
    • Protein or peptide: Ribosomal protein S15aRibosome
    • Protein or peptide: Ribosomal protein S23
    • Protein or peptide: 40S ribosomal protein S24
    • Protein or peptide: ribosomal protein eS25
    • Protein or peptide: 40S ribosomal protein S26
    • Protein or peptide: 40S ribosomal protein S27
    • Protein or peptide: 40S ribosomal protein S28
    • Protein or peptide: uS14
    • Protein or peptide: 40S ribosomal protein S30
    • Protein or peptide: eS31
    • Protein or peptide: ribosomal protein RACK1
    • Protein or peptide: L8
    • Protein or peptide: uL3
    • Protein or peptide: uL4
    • Protein or peptide: 60S ribosomal protein L5
    • Protein or peptide: 60S ribosomal protein L6
    • Protein or peptide: uL30
    • Protein or peptide: L7a
    • Protein or peptide: L9
    • Protein or peptide: 60S ribosomal protein L10
    • Protein or peptide: 60S ribosomal protein L11
    • Protein or peptide: L13
    • Protein or peptide: Ribosomal protein L14
    • Protein or peptide: Ribosomal protein L15
    • Protein or peptide: 60S RIBOSOMAL PROTEIN UL13
    • Protein or peptide: uL22
    • Protein or peptide: L18
    • Protein or peptide: 60S ribosomal protein L19
    • Protein or peptide: 60S ribosomal protein L18a
    • Protein or peptide: eL21
    • Protein or peptide: L22
    • Protein or peptide: eL14
    • Protein or peptide: uL23
    • Protein or peptide: Ribosomal protein L26
    • Protein or peptide: 60S ribosomal protein L27
    • Protein or peptide: uL15
    • Protein or peptide: eL29
    • Protein or peptide: eL30
    • Protein or peptide: eL31
    • Protein or peptide: eL32CD59
    • Protein or peptide: eL33
    • Protein or peptide: 60S ribosomal protein L34
    • Protein or peptide: uL29
    • Protein or peptide: 60S ribosomal protein L36
    • Protein or peptide: Ribosomal protein L37
    • Protein or peptide: L38
    • Protein or peptide: eL39
    • Protein or peptide: 60S RIBOSOMAL PROTEIN EL40
    • Protein or peptide: 60s ribosomal protein l41
    • Protein or peptide: eL42
    • Protein or peptide: ribosomal protein eL43
    • Protein or peptide: eL28
    • Protein or peptide: 60S acidic ribosomal protein P0
    • Protein or peptide: uL12
    • RNA: mRNAMessenger RNA
    • RNA: P/E-Site tRNA
    • Protein or peptide: Ribosomal protein
    • Protein or peptide: Sec61Beta
    • Protein or peptide: 60S ribosomal protein L24-like proteinRibosome
  • RNA: A/P-Site tRNA
  • Ligand: MAGNESIUM ION
  • Ligand: BLASTICIDIN S
  • Ligand: ZINC ION

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Supramolecule #1: Mammalian pre-termination 80S ribosome with Hybrid-P/E and -A/P s...

SupramoleculeName: Mammalian pre-termination 80S ribosome with Hybrid-P/E and -A/P site tRNAs bound by Blasticidin S.
type: complex / ID: 1 / Parent: 0 / Macromolecule list: #1-#78, #80-#86
Details: Rabbit reticulocyte lysate derived (in vitro transcription-FLAG affinity purified) ribosomal complex.
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 3.8 MDa

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Macromolecule #1: 28S Ribosomal RNA

MacromoleculeName: 28S Ribosomal RNA / type: rna / ID: 1 / Number of copies: 1
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 1.2266193749999998 MDa
SequenceString: CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAA AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGAAA UGUGGCGUAC G GAAGACCC ...String:
CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAA AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGAAA UGUGGCGUAC G GAAGACCC ACUCCCCGGC GCCGACACAC GGGGGCCCAA GUCCUUCUGA UCGAGGCCCA GCCCGUGGAC GGUGUGAGGC CG GUAGCGG CCCCCGGCGC GCCGGGCCCG GGUCUUCCCG GAGUCGGGUU GCUUGGGAAU GCAGCCCAAA GCGGGUGGUA AAC UCCAUC UAAGGCUAAA UACCGGCACG AGACCGAUAG UCAACAAGUA CCGUAAGGGA AAGUUGAAAA GAACUUUGAA GAGA GAGUU CAAGAGGGCG UGAAACCGUU AAGAGGUAAA CGGGUGGGGU CCGCGCAGUC CGCCCGGAGG AUUCAACCCG GCGGC GCGG UCCGGCCGUG CCGGCGGACA GGCGGAUCUA CCCCGCUCCC ACACACACAC AGUCGGCGGG GGACCGCCCC CCGGCC GGC GACCGGCCGC CGCCGGGCGC AUUUCCACCG CGGCGGUGCG CCGCGACCGG CUCCGGGACG GCUGGGAAGG CCCCGGC GG GGAAGGUGGC CCGGGGGACA CACACACACC CCGGGUGUUA CAGCCCCGCC CCGGCAGCAG CAGCUCGCCG AAUCCCGG G GCCGAGGGAG CGAGACCCGU GCGCCGCGCU CUCCCCCCUC ACACACACAC AGGGGGGGCC GGGCCACCCC UCCCACGGC GCGACCGCUC UCCCACCCAC ACACACACAG GGGGGCGGGG CGGACUGUCC CCAGUGCGCC CCGGGCGGGU CGCGCCGUCG GGCCCGGGG GAGGUUCUCU CGGGGCCACA CACACACACA GCGUCCCCCG CGAGCGCACG GGGUCGGCGG CGAUGUCGGC U ACCCACCC GACCCGUCUU GAAACACGGA CCAAGGAGUC UAACACGUGC GCGAGUCGGG GGCUACAACG AAAGCCGCCG UG GCGCAAU GAAGGUGAAG GCCGGCGGCG ACCGCCGCCG GCCGAGGUGG GAUCCCGAGG CCUAUCCAGU CCGCCGAGGG CGC ACCACC GGCCCGUCUC GCCCGCCGCG CCGGGGAGGU GGAGCACGAG CGCACGUGUU AGGACCCGAA AGAUGGUGAA CUAU GCCUG GGCAGGGCGA AGCCAGAGGA AACUCUGGUG GAGGUCCGUA GCGGUCCUGA CGUGCGAAUC GGUCGUCCGA CCUGG GUAU AGGGGCGAAA GACUAAUCGA ACCAUCUAGU AGCUGGUUCC CUCCAAAGUU UCCCUCAGGA UAGCUGGCGC UCUCAC ACA CACACACGCA GUUUUAUCCG GUAAAGCGAA UGAUUAGAGG UCUUGGGGCC GAAACGAUCU CAACCUAUUC UCAAACU UU AAAUGGGUAA GAAGCCCGGC UCGCUGGUGU GGAGCCGGGC GUGGAAUGCG AGUGCCUAGU GGGCCACUUU UGGUAAGC A GAACUGGCGC UGCGGGAUGA ACCGAACGCC GGGUUAAGGC GCCCGAUGCC GACGCUCAUC AGACCCCAGA AAAGGUGUU GGUUGAUAUA GACAGCAGGA UGGUGGCCAU GGAAGUCGGA AUCCGCUAAG GAGUGUGUAA CAACUCACCU GCCGAAUCAA CUAGCCCUG AAAAUGGAUG GCGCUGGAGC GUCGGGCCCA UACCCGGCCG UCGCUGGCAG UCGGCAGAGC GAGAAAGAGA G UGGACACA CACACACGCG GACGCUACGC CGCGACGAGU AGGAGGGCCG CUGCGGUGAG CCUUGAAGCC UAGGGCGCGG GC CCGGGUG GAGCCGCCGC AGGUGCAGAU CUUGGUGGUA GUAGCAAAUA UUCAAACGAG AACUUUGAAG GCCGAAGUGG AGA AGGGUU CCAUGUGAAC AGCAGUUGAA CAUGGGUCAG UCGGUCCUGA GAGAUGGGCG AGCGCCGUUC CGAAGGGACG GGCG AUGGC CUCCGUUGCC CUCAGCCGAU CGAAAGGGAG UCGGGUUCAG AUCCCCGAAU CCGGAGUGGC GGAGAUGGGC GCCGC GAGG CGUCCAGUGC GGUAACGCGA CCGAUCCCGG AGAAGCCGGC GGGAGCCCCG GGGAGAGUUC UCUUUUCUUU GUGAAG GGC AGGGCGCCCU GGAAUGGGUU CGCCCCGAGA GAGGGGCCCG UGCCUUGGAA AGCGUCGCGG UUCCGGCGGC GUCCGGU GA GCUCUCGCUG GCCCUUGAAA AUCCGGGGGA GAGGGUGUAA AUCUCGCGCC GGGCCGUACC CAUAUCCGCA GCAGGUCU C CAAGGUGAAC AGCCUCUGGC AUGUUGGAAC AAUGUAGGUA AGGGAAGUCG GCAAGCCGGA UCCGUAACUU CGGGAUAAG GAUUGGCUCU AAGGGCUGAC ACACACACAG CAGCCGACUU AGAACUGGUG CGGACCAGGG GAAUCCGACU GUUUAAUUAA AACAAAGCA UCGCGAAGGC CCGCGGCGGG UGUUGACGCG AUGUGAUUUC UGCCCAGUGC UCUGAAUGUC AAAGUGAAGA A AUUCAAUG AAGCGCGGGU AAACGGCGGG AGUAACUAUG ACUCUCUUAA GGUAGCCAAA UGCCUCGUCA UCUAAUUAGU GA CGCGCAU GAAUGGAUGA ACGAGAUUCC CACUGUCCCU ACCUACUAUC CAGCGAAACC ACAGCCAAGG GAACGGGCUU GGC GGAAUC AGCGGGGAAA GAAGACCCUG UUGAGCUUGA CUCUAGUCUG GCACGGUGAA GAGACAUGAG AGGUGUAGAA UAAG UGGGA GGCCCACACA CACACAGGGC CGCCGGUGAA AUACCACUAC UCUGAUCGUU UUUUCACUGA CCCGGUGAGG CGGGG GGGC GAGCCACACA GGGCUCUCGC UUCUGGCGCC AAGCGCCCGG CCACACACAG GCCGGGCGCG ACCCGCUCCG GGGACA GUG CCAGGUGGGG AGUUUGACUG GGGCGGUACA CCUGUCAAAC GGUAACGCAG GUGUCCUAAG GCGAGCUCAG GGAGGAC AG AAACCUCCCG UGGAGCAGAA GGGCAAAAGC UCGCUUGAUC UUGAUUUUCA GUACGAAUAC AGACCGUGAA AGCGGGGC C UCACGAUCCU UCUGACCUUU UGGGUUUUAA GCAGGAGGUG UCAGAAAAGU UACCACAGGG AUAACUGGCU UGUGGCGGC CAAGCGUUCA UAGCGACGUC GCUUUUUGAU CCUUCGAUGU CGGCUCUUCC UAUCAUUGUG AAGCAGAAUU CACCAAGCGU UGGAUUGUU CACCCACUAA UAGGGAACGU GAGCUGGGUU UAGACCGUCG UGAGACAGGU UAGUUUUACC CUACUGAUGA U GUGUUGUU GCCAUGGUAA UCCUGCUCAG UACGAGAGGA ACCGCAGGUU CAGACAUUUG GUGUAUGUGC UUGGCUGAGG AG CCAAUGG GGCGAAGCUA CCAUCUGUGG GAUUAUGACU GAACGCCUCU AAGUCAGAAU CCCGCCCAGG CGGAACGAUA ACA CAGCGC CGACGAGCCU CGGUUGGCCU CGGAUAGCCG GUCCCCCGCC ACACACACAC ACGGGGUCCG GUGCGGAGAG CCCU UCGUC CCGGGAAACG GGGACCGGCC GGAAAGGGGG CCGCCCUCUC GCCCGUCACG CACCGCACGU UCGUGGGGAA CCUGG CGCU AAACCAUUCG UAGACGACCU GCUUCUGGGU CGGGGUUUCG UACGUAGCAG AGCAGCUACA CAGCUGCGAU CUAUUG AAA GUCAGCCCUC GACACAAGGG UUUGU

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Macromolecule #2: 5S Ribosomal RNA

MacromoleculeName: 5S Ribosomal RNA / type: rna / ID: 2 / Number of copies: 1
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 38.691914 KDa
SequenceString:
GUCUACGGCC AUACCACCCU GAACGCGCCC GAUCUCGUCU GAUCUCGGAA GCUAAGCAGG GUCGGGCCUG GUUAGUACUU GGAUGGGAG ACCGCCUGGG AAUACCGGGU GCUGUAGGCU U

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Macromolecule #3: 5.8S Ribosomal RNA

MacromoleculeName: 5.8S Ribosomal RNA / type: rna / ID: 3 / Number of copies: 1
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 48.545672 KDa
SequenceString:
CGACUCUUAG CGGUGGAUCA CUCGGCUCGU GCGUCGAUGA AGAACGCAGC UAGCUGCGAG AAUUAAUGUG AAUUGCAGGU UGAUCAUCG ACACUUCGAA CGCACUUGCG GCCCCGGGUU CCUCCCGGGG CUACGCCUGU CUGAGCGUCG CU

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Macromolecule #4: 18S Ribosomal RNA

MacromoleculeName: 18S Ribosomal RNA / type: rna / ID: 4 / Number of copies: 1
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 586.374938 KDa
SequenceString: UACCUGGUUG AUCCUGCCAG UAGCAUAUGC UUGUCUCAAA GAUUAAGCCA UGCAUGUCUA AGUACGCACG GCCGGUACAG UGAAACUGC GAAUGGCUCA UUAAAUCAGU UAUGGUUCCU UUGGUCGCUC GACACACACA UACUUGGAUA ACUGUGGUAA U UCUAGAGC ...String:
UACCUGGUUG AUCCUGCCAG UAGCAUAUGC UUGUCUCAAA GAUUAAGCCA UGCAUGUCUA AGUACGCACG GCCGGUACAG UGAAACUGC GAAUGGCUCA UUAAAUCAGU UAUGGUUCCU UUGGUCGCUC GACACACACA UACUUGGAUA ACUGUGGUAA U UCUAGAGC UAAUACAUGC CGACGGGCGC UGACCCCCUU CGCGGGGGGG AUGCGUGCAU UUAUCAGAUC AAAACCAACC CG GUCAACA CACACACAGG CGGCUUUGGU GACUCUAGAU AACCUCGGGC CGAUCGCACG CCCACACAGG CGGCGACGAC CCA UUCGAA CGUCUGCCCU AUCAACUUUC GAUGGUAGUC GCCGUGCCUA CCAUGGUGAC CACGGGUGAC GGGGAAUCAG GGUU CGAUU CCGGAGAGGG AGCCUGAGAA ACGGCUACCA CAUCCAAGGA AGGCAGCAGG CGCGCAAAUU ACCCACUCCC GACCC GGGG AGGUAGUGAC GAAAAAUAAC AAUACAGGAC UCUUUCGAGG CCCUGUAAUU GGAAUGAGUC CACUUUAAAU CCUUUA ACG AGGAUCCAUU GGAGGGCAAG UCUGGUGCCA GCAGCCGCGG UAAUUCCAGC UCCAAUAGCG UAUAUUAAAG UUGCUGC AG UUAAAAAGCU CGUAGUUGGA UCUUGGGAGC GGGCGGACAC ACACACACCG UCCGUCCCCA CACACUGCCU CUCGGCGC C CCACACACAC ACAGGGGCCC GAAGCGUUUA CUUUGAAAAA AUUAGAGUGU UCAAAGCAGG CCACACACGC CUGGAUACC GCAGCUAGGA AUAAUGGAAU AGGACCGCGG UUCUAUUUUG UUGGUUUUCG GAACUGAGGC CAUGAUUAAG AGGGACGGCC GGGGGCAUU CGUAUUGCGC CGCUAGAGGU GAAAUUCUUG GACCGGCGCA AGACGGACCA GAGCGAAAGC AUUUGCCAAG A AUGUUUUC AUUAAUCAAG AACGAAAGUC GGAGGUUCGA AGACGAUCAG AUACCGUCGU AGUUCCGACC AUAAACGAUG CC GACUGGC GAUGCGGCGG CGUUAUUCCC AUGACCCGCC GGGCAGCUUC CGGGAAACCA AAGUCUUUGG GUUCCGGGGG GAG UAUGGU UGCAAAGCUG AAACUUAAAG GAAUUGACGG AAGGGCACCA CCAGGAGUGG AGCCUGCGGC UUAAUUUGAC UCAA CACGG GAAACCUCAC CCGGCCCGGA CACGGACAGG AUUGACAGAU UGAUAGCUCU UUCUCGAUUC CGUGGGUGGU GGUGC AUGG CCGUUCUUAG UUGGUGGAGC GAUUUGUCUG GUUAAUUCCG AUAACGAACG AGACUCUGGC AUGCUAACUA GUUACG CGA CCCACACACG GUCGGCGUAC ACAAACUUCU UAGAGGGACA AGUGGCGUUC AGCCACCCGA GAUUGAGCAA UAACAGG UC UGUGAUGCCC UUAGAUGUCC GGGGCUGCAC GCGCGCUACA CUGACUGGCU CAGCGUGUGC CUACCCUACG CCGGCAGG C GCGGGUAACC CGUUGAACCC CAUUCGUGAU GGGGAUCGGG GAUUGCAAUU AUUCCCCAUG AACGAGGAAU UCCCAGUAA GUGCGGGUCA UAAGCUUGCG UUGAUUAAGU CCCUGCCCUU UGUACACACC GCCCGUCGCU ACUACCGAUU GGAUGGUUUA GUGAGGCCC UCGGAUCGGC CCCGCCGGGG UACACACACA GCCCUGGCGG AGCGCUGAGA AGACGGUCGA ACUUGACUAU C UAGAGGAA GUAAAAGUCG UAACAAGGUU UCCGUAGGUG AACCUGCGGA AGGAUCAUUA

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Macromolecule #79: A/P-Site tRNA

MacromoleculeName: A/P-Site tRNA / type: rna / ID: 79 / Number of copies: 1
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 23.825205 KDa
SequenceString:
GUCUCCGUAG UGUAGGGUAU CACGUUCGCC UAACACGCGA AAGGUCCUCG GUUCGAAACC GGGCGGAAAC ACCA

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Macromolecule #82: mRNA

MacromoleculeName: mRNA / type: rna / ID: 82 / Number of copies: 1
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 5.719419 KDa
SequenceString:
UGCUUAAGAU UUGAAACU

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Macromolecule #83: P/E-Site tRNA

MacromoleculeName: P/E-Site tRNA / type: rna / ID: 83 / Number of copies: 1
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 24.118275 KDa
SequenceString:
GCCCGGAUAG CUCAGCGUGU AGAGCAUCAG ACUUUUAAUC UGAGGGUCCA GGGUUCAAGU CCCUGUUCGG GCGCC

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Macromolecule #5: 40S ribosomal protein SA

MacromoleculeName: 40S ribosomal protein SA / type: protein_or_peptide / ID: 5 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 32.958016 KDa
SequenceString: MSGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL AARAIVAIEN PADVSVISSR NTGQRAVLK FAAATGATPI AGRFTPGTFT NQIQTAFREP RLLVVTDPRA DHQPLTEASY VNLPTIALCN TDSPLRYVDI A IPCNNKGA ...String:
MSGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL AARAIVAIEN PADVSVISSR NTGQRAVLK FAAATGATPI AGRFTPGTFT NQIQTAFREP RLLVVTDPRA DHQPLTEASY VNLPTIALCN TDSPLRYVDI A IPCNNKGA HSVGLMWWML AREVLRMRGT ISREHPWEVM PDLYFYRDPE EIEKEEQAAA EKAVTKEEFQ GEWTAPAPEF TA TQPEVAD WSEGVQVPSV PIQQFPTEDW SAQPATEDWS AAPTAQATEW VGTTTEWS

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Macromolecule #6: 40S ribosomal protein S3a

MacromoleculeName: 40S ribosomal protein S3a / type: protein_or_peptide / ID: 6 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 29.94201 KDa
SequenceString: MAVGKNKRLT KGGKKGAKKK VVDPFSKKDW YDVKAPAMFN IRNIGKTLVT RTQGTKIASD GLKGRVFEVS LADLQNDEVA FRKFKLITE DVQGKNCLTN FHGMDLTRDK MCSMVKKWQT MIEAHVDVKT TDGYLLRLFC VGFTKKRNNQ IRKTSYAQHQ Q VRQIRKKM ...String:
MAVGKNKRLT KGGKKGAKKK VVDPFSKKDW YDVKAPAMFN IRNIGKTLVT RTQGTKIASD GLKGRVFEVS LADLQNDEVA FRKFKLITE DVQGKNCLTN FHGMDLTRDK MCSMVKKWQT MIEAHVDVKT TDGYLLRLFC VGFTKKRNNQ IRKTSYAQHQ Q VRQIRKKM MEIMTREVQT NDLKEVVNKL IPDSIGKDIE KACQSIYPLH DVFVRKVKML KKPKFELGKL MELHGEGGSS GK AAGDETG AKVERADGYE PPVQESV

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Macromolecule #7: 40S ribosomal protein S2

MacromoleculeName: 40S ribosomal protein S2 / type: protein_or_peptide / ID: 7 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Bovine (cattle)
Molecular weightTheoretical: 27.995727 KDa
SequenceString: MADDAGAAGG PGGLGARGGK AEDKEWLPVT KLGRLVKDMK IKSLEEIYLF SLPIKESEII DFFLGASLKD EVLKIMPVQK QTRAGQRTR FKAFVAIGDY NGHVGLGVKC SKEVATAIRG AIILAKLSIV PVRRGYWGNK IGKPHTVPCK VTGRCGSVLV R LIPAPRGT ...String:
MADDAGAAGG PGGLGARGGK AEDKEWLPVT KLGRLVKDMK IKSLEEIYLF SLPIKESEII DFFLGASLKD EVLKIMPVQK QTRAGQRTR FKAFVAIGDY NGHVGLGVKC SKEVATAIRG AIILAKLSIV PVRRGYWGNK IGKPHTVPCK VTGRCGSVLV R LIPAPRGT GIVSAPVPKK LLMMAGIDDC YTSARGCTAT LGNFAKATFD AISKTYSYLT PDLWKETVFT KSPYQEFTDH LV KTHTRVS VQRTQAPAVA TT

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Macromolecule #8: 40S ribosomal protein S3

MacromoleculeName: 40S ribosomal protein S3 / type: protein_or_peptide / ID: 8 / Number of copies: 1 / Enantiomer: LEVO / EC number: DNA-(apurinic or apyrimidinic site) lyase
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 31.146607 KDa
SequenceString: MSARRRRRRA AFRRRAEPFI PISVREPLPF LSAARGGKMA VQISKKRKFV ADGIFKAELN EFLTRELAED GYSGVEVRVT PTRTEIIIL ATRTQNVLGE KGRRIRELTA VVQKRFGFPE GSVELYAEKV ATRGLCAIAQ AESLRYKLLG GLAVRRACYG V LRFIMESG ...String:
MSARRRRRRA AFRRRAEPFI PISVREPLPF LSAARGGKMA VQISKKRKFV ADGIFKAELN EFLTRELAED GYSGVEVRVT PTRTEIIIL ATRTQNVLGE KGRRIRELTA VVQKRFGFPE GSVELYAEKV ATRGLCAIAQ AESLRYKLLG GLAVRRACYG V LRFIMESG AKGCEVVVSG KLRGQRAKSM KFVDGLMIHS GDPVNYYVDT AVRHVLLRQG VLGIKVKIML PWDPSGKIGP KK PLPDHVS IVEPKDEILP TTPISEQKGG KPEPPAMPQP VPTA

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Macromolecule #9: S4

MacromoleculeName: S4 / type: protein_or_peptide / ID: 9 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 29.523674 KDa
SequenceString: ARGPKKHLKR VAAPKHWMLD KLTGVFAPRP STGPHKLREC LPLIIFLRNR LKYALTGDEV KKICMQRFIK IDGKVRTDIT YPAGFMDVI SIDKTGENFR LIYDTKGRFA VHRITPEEAK YKLCKVRKIF VGTKGIPHLV THDARTIRYP DPLIKVNDTI Q IDLETGKI ...String:
ARGPKKHLKR VAAPKHWMLD KLTGVFAPRP STGPHKLREC LPLIIFLRNR LKYALTGDEV KKICMQRFIK IDGKVRTDIT YPAGFMDVI SIDKTGENFR LIYDTKGRFA VHRITPEEAK YKLCKVRKIF VGTKGIPHLV THDARTIRYP DPLIKVNDTI Q IDLETGKI TDFIKFDTGN LCMVTGGANL GRIGVITNRE RHPGSFDVVH VKDANGNSFA TRLSNIFVIG KGNKPWISLP RG KGIRLTI AEERDKRLAA KQSSG

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Macromolecule #10: Ribosomal protein S5

MacromoleculeName: Ribosomal protein S5 / type: protein_or_peptide / ID: 10 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 23.04465 KDa
SequenceString: MMTEWETAAP AVAETPDIKL FGKWSTDDVQ INDISLQDYI AVKEKYAKYL PHSAGRYAAK RFRKAQCPIV ERLTNSMMMH GRNNGKKLM TVRIVKHAFE IIHLLTGENP LQVLVNAIIN SGPREDSTRI GRAGTVRRQA VDVSPLRRVN QAIWLLCTGA R EAAFRNIK ...String:
MMTEWETAAP AVAETPDIKL FGKWSTDDVQ INDISLQDYI AVKEKYAKYL PHSAGRYAAK RFRKAQCPIV ERLTNSMMMH GRNNGKKLM TVRIVKHAFE IIHLLTGENP LQVLVNAIIN SGPREDSTRI GRAGTVRRQA VDVSPLRRVN QAIWLLCTGA R EAAFRNIK TIAECLADEL INAAKGSSNS YAIKKKDELE RVAKSNR

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Macromolecule #11: 40S ribosomal protein S6

MacromoleculeName: 40S ribosomal protein S6 / type: protein_or_peptide / ID: 11 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 30.070432 KDa
SequenceString: LFRGASEAVG SLKMKLNISF PATGCQKLIE VDDERKLRTF YEKRMATEVA ADALGEEWKG YVVRISGGND KQGFPMKQGV LTHGRVRLL LSKGHSCYRP RRTGERKRKS VRGCIVDANL SVLNLVIVKK GEKDIPGLTD TTVPRRLGPK RASRIRKLFN L SKEDDVRQ ...String:
LFRGASEAVG SLKMKLNISF PATGCQKLIE VDDERKLRTF YEKRMATEVA ADALGEEWKG YVVRISGGND KQGFPMKQGV LTHGRVRLL LSKGHSCYRP RRTGERKRKS VRGCIVDANL SVLNLVIVKK GEKDIPGLTD TTVPRRLGPK RASRIRKLFN L SKEDDVRQ YVVRKPLNKE GKKPRTKAPK IQRLVTPRVL QHKRRRIALK KQRTKKNKEE AAEYAKLLAK RMKEAKEKRQ EQ IAKRRRL SSLRASTSKS ESSQK

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Macromolecule #12: ribosomal protein eS7

MacromoleculeName: ribosomal protein eS7 / type: protein_or_peptide / ID: 12 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 21.716387 KDa
SequenceString:
SAKIVKPNGE KPDEFESGIS QALLELEMNS DLKAQLRELN ITAAKEIEVG GGRKAIIIFV PVPQLKSFQK IQVRLVRELE KKFSGKHVV FIAQRRILPK PTRKSRTKNK QKRPRSRTLT AVHDAILEDL VFPSEIVGKR IRVKLDGSRL IKVHLDKAQQ N NVEHKVET FSGVYKKLTG KDVNFEFPEF QL

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Macromolecule #13: 40S ribosomal protein S8

MacromoleculeName: 40S ribosomal protein S8 / type: protein_or_peptide / ID: 13 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 24.003012 KDa
SequenceString: GISRDNWHKR RKTGGKRKPY HKKRKYELGR PAANTKIGPR RIHTVRVRGG NKKYRALRLD VGNFSWGSEC CTRKTRIIDV VYNASNNEL VRTKTLVKNC IVLIDSTPYR QWYESHYALP LGRKKGAKLT PEEEEILNKK RSKKIQKKYD ERKKNAKISS L LEEQFQQG ...String:
GISRDNWHKR RKTGGKRKPY HKKRKYELGR PAANTKIGPR RIHTVRVRGG NKKYRALRLD VGNFSWGSEC CTRKTRIIDV VYNASNNEL VRTKTLVKNC IVLIDSTPYR QWYESHYALP LGRKKGAKLT PEEEEILNKK RSKKIQKKYD ERKKNAKISS L LEEQFQQG KLLACIASRP GQCGRADGYV LEGKELEFYL RKIKARKG

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Macromolecule #14: 40S ribosomal protein S9

MacromoleculeName: 40S ribosomal protein S9 / type: protein_or_peptide / ID: 14 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 22.65559 KDa
SequenceString: MPVARSWVCR KTYVTPRRPF EKSRLDQELK LIGEYGLRNK REVWRVKFTL AKIRKAAREL LTLDEKDPRR LFEGNALLRR LVRIGVLDE GKMKLDYILG LKIEDFLERR LQTQVFKLGL AKSIHHARVL IRQRHIRVRK QVVNIPSFIV RLDSQKHIDF S LRSPYGGG ...String:
MPVARSWVCR KTYVTPRRPF EKSRLDQELK LIGEYGLRNK REVWRVKFTL AKIRKAAREL LTLDEKDPRR LFEGNALLRR LVRIGVLDE GKMKLDYILG LKIEDFLERR LQTQVFKLGL AKSIHHARVL IRQRHIRVRK QVVNIPSFIV RLDSQKHIDF S LRSPYGGG RPGRVKRKNA KKGQGGAGAG EDEEED

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Macromolecule #15: 40S ribosomal protein S10

MacromoleculeName: 40S ribosomal protein S10 / type: protein_or_peptide / ID: 15 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 17.422133 KDa
SequenceString:
MLMPKKNRIA IYELLFKEGV MVAKKDVHMP KHPELADKNV PNLHVMKAMQ SLKSRGYVKE QFAWRHFYWY LTNEGIQYLR DYLHLPPEI VPATLRRSRP ETGRPRPKGL EGERPARLTR GEADRDTYRR SAVPSGADKK AEAGAGSATE FQ

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Macromolecule #16: 40S ribosomal protein S11

MacromoleculeName: 40S ribosomal protein S11 / type: protein_or_peptide / ID: 16 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 18.513824 KDa
SequenceString:
MADIQTERAY QKQPTIFQNK KRVLQGETSK EKLPRYYKNI GLGFKTPKEA IEGTYIDKKC PFTGNVSIRG RILSGVVTKM KMQRTIVIR RDYLHYIRKY NRFEKRHKNM SVHLSPCFRD VQIGDIVTVG ECRPLSKTVR FNVLKVTKAA GTKKQFQKF

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Macromolecule #17: 40S ribosomal protein S12

MacromoleculeName: 40S ribosomal protein S12 / type: protein_or_peptide / ID: 17 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 13.70907 KDa
SequenceString:
GVMDVNTALQ EVLKTALIHD GLARGIREAA KALDKRQAHL CVLASNCDEP MYVKLVEALC AEHQINLIKV DDNKKLGEWV GLCKIDREG KPRKVVGCSC VVVKDYGKES QAKDVIEEYF KCKK

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Macromolecule #18: ribosomal protein uS15

MacromoleculeName: ribosomal protein uS15 / type: protein_or_peptide / ID: 18 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 17.057113 KDa
SequenceString:
GRMHAPGKGL SQSALPYRRS VPTWLKLTSD DVKEQIYKLA KKGLTPSQIG VILRDSHGVA QVRFVTGNKI LRILKSKGLA PDLPEDLYH LIKKAVAVRK HLERNRKDKD AKFRLILIES RIHRLARYYK TKRVLPPNWK YESSTASALV

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Macromolecule #19: uS11

MacromoleculeName: uS11 / type: protein_or_peptide / ID: 19 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 18.133984 KDa
SequenceString:
MKARALSGSG VRRRRAAMAP RKGKEKKEEQ VISLGPQVAE GENVFGVCHI FASFNDTFVH VTDLSGKETI CRVTGGMKVK ADRDESSPY AAMLAAQDVA QRCKELGITA LHIKLRATGG NRTKTPGPGA QSALRALARS GMKIGRIEDV TPIPSDSTRR K GGRRGRRL

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Macromolecule #20: 40S ribosomal protein uS19

MacromoleculeName: 40S ribosomal protein uS19 / type: protein_or_peptide / ID: 20 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 17.049182 KDa
SequenceString:
MAEVEQKKKR TFRKFTYRGV DLDQLLDMSY EQLMQLYSAR QRRRLSRGLR RKQHSLLKRL RKAKKEAPPM EKPEVVKTHL RDMIILPEM VGSMVGVYNG KTFNQVEIKP EMIGHYLGEF SITYKPVKHG RPGIGATHSS RFIPLK

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Macromolecule #21: Ribosomal protein S16

MacromoleculeName: Ribosomal protein S16 / type: protein_or_peptide / ID: 21 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 17.585736 KDa
SequenceString:
RGVELVLVLG AMPSKGPLQS VQVFGRKKTA TAVAHCKRGN GLIKVNGRPL EMIEPRTLQY KLLEPVLLLG KERFAGVDIR VRVKGGGHV AQIYAIRQSI SKALVAYYQK YVDEASKKEI KDILIQYDRT LLVADPRRCE SKKFGGPGAR ARYQKSYR

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Macromolecule #22: 40S ribosomal protein S17

MacromoleculeName: 40S ribosomal protein S17 / type: protein_or_peptide / ID: 22 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 16.782648 KDa
SequenceString:
MKSKKELRVQ KGRVRTKTVK KAARVIIEKY YTRLGNDFHT NKRVCEEIAI IPSKKLRNKI AGYVTHLMKR IQRGPVRGIS IKLQEEERE RRDNYVPEVS ALDQEIIEVD PDTKEMLKLL DFGSLSNLQV TQPTVGMNFK TPRGAV

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Macromolecule #23: 40S ribosomal protein uS13

MacromoleculeName: 40S ribosomal protein uS13 / type: protein_or_peptide / ID: 23 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 17.759777 KDa
SequenceString:
MSLVIPEKFQ HILRVLNTNI DGRRKIAFAI TAIKGVGRRY AHVVLRKADI DLTKRAGELT EDEVERVITI MQNPRQYKIP DWFLNRQKD VKDGKYSQVL ANGLDNKLRE DLERLKKIRA HRGLRHFWGL RVRGQHTKTT GRRGRTVGVS KKK

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Macromolecule #24: S19

MacromoleculeName: S19 / type: protein_or_peptide / ID: 24 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 16.10664 KDa
SequenceString:
MPGVTVKDVN QQEFVRALAA FLKKSGKLKV PEWVDTVKLA KHKELAPYDE NWFYTRAAST ARHLYLRGGA GVGSMTKIYG GRQRNGVMP SHFSRGSKSV ARRVLQALEG LKMVEKDQDG GRKLTPQGQR DLDRIAGQVA AAKKKH

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Macromolecule #25: 40S ribosomal protein S20

MacromoleculeName: 40S ribosomal protein S20 / type: protein_or_peptide / ID: 25 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 14.60308 KDa
SequenceString:
MARSQYPLDS ALAFKDTGKA PVEQEVAIHR IRITLTSRNV KSLEKVCADL IRGAKEKNLK VKGPVRMPTK TLRITTRKTP CGEGSKTWD RFQMRIHKRL IDLHSPSEIV KQITSISIEP GVEVEVTIAD A

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Macromolecule #26: 40S ribosomal protein S21

MacromoleculeName: 40S ribosomal protein S21 / type: protein_or_peptide / ID: 26 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 9.124389 KDa
SequenceString:
MQNDAGEFVD LYVPRKCSAS NRIIGAKDHA SIQMNVAEVD KVTGRFNGQF KTYAICGAIR RMGESDDSIL RLAKADGIVS KNF

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Macromolecule #27: Ribosomal protein S15a

MacromoleculeName: Ribosomal protein S15a / type: protein_or_peptide / ID: 27 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 15.778584 KDa
SequenceString:
MHEASLAATM VRMNVLADAL KSINNAEKRG KRQVLIRPCS KVIVRFLTVM MKHGYIGEFE IIDDHRAGKI VVNLTGRLNK CGVISPRFD VQLKDLEKWQ NNLLPSRQFG FIVLTTSAGI MDHEEARRKH TGGKILGFFF

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Macromolecule #28: Ribosomal protein S23

MacromoleculeName: Ribosomal protein S23 / type: protein_or_peptide / ID: 28 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 15.626392 KDa
SequenceString:
GKCRGLRTAR KLRSHRRDQK WHDKQYKKAH LGTALKANPF GGASHAKGIV LEKVGVEAKQ PNSAIRKCVR VQLIKNGKKI TAFVPNDGC LNFIEENDEV LVAGFGRKGH AVGDIPGVRF KVVKVANVSL LALYKGKKER PR

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Macromolecule #29: 40S ribosomal protein S24

MacromoleculeName: 40S ribosomal protein S24 / type: protein_or_peptide / ID: 29 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 17.007125 KDa
SequenceString:
MNDTVTIRTR KFMTNRLLQR KQMVIDVLHP GKATVPKTEI REKLAKMYKT TPDVIFVFGF RTHFGGGKTT GFGMIYDSLD YAKKNEPKH RLARHGLYEK KKTSRKQRKE RKNRMKKVRG TAKANVGAGK KEVSWRWITA EGVKILQ

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Macromolecule #30: ribosomal protein eS25

MacromoleculeName: ribosomal protein eS25 / type: protein_or_peptide / ID: 30 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 22.090133 KDa
SequenceString: RDKLNNLVLF DKATYDKLCK EVPNYKLITP AVVSERLKIR GSLARAALQE LLSKGLIKLV SKHRAQVIYT RNTKGMKDDK KKKDAGKSA KKDKDPVNKS GGKAKKKKWS KGKVRDKLNN LVLFDKATYD KLCKEVPNYK LITPAVVSER LKIRGSLARA A LQELLSKG ...String:
RDKLNNLVLF DKATYDKLCK EVPNYKLITP AVVSERLKIR GSLARAALQE LLSKGLIKLV SKHRAQVIYT RNTKGMKDDK KKKDAGKSA KKDKDPVNKS GGKAKKKKWS KGKVRDKLNN LVLFDKATYD KLCKEVPNYK LITPAVVSER LKIRGSLARA A LQELLSKG LIKLVSKHRA QVIYTRNTKG GDAPAAGEDA

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Macromolecule #31: 40S ribosomal protein S26

MacromoleculeName: 40S ribosomal protein S26 / type: protein_or_peptide / ID: 31 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 13.147561 KDa
SequenceString:
MTKKRRNNGR AKKGRGHVQP IRCTNCARCV PKDKAIKKFV IRNIVEAAAV RDISEASVFD AYVLPKLYVK LHYCVSCAIH SKVVRNRSR EARKDRTPPP RFRPAVSVAL STADMVGA

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Macromolecule #32: 40S ribosomal protein S27

MacromoleculeName: 40S ribosomal protein S27 / type: protein_or_peptide / ID: 32 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 9.480186 KDa
SequenceString:
MPLAKDLLHP SPEEEKRKHK KKRLVQSPNS YFMDVKCPGC YKITTVFSHA QTVVLCVGCS TVLCQPTGGK ARLTEGCSFR RKQH

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Macromolecule #33: 40S ribosomal protein S28

MacromoleculeName: 40S ribosomal protein S28 / type: protein_or_peptide / ID: 33 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 7.836005 KDa
SequenceString:
MDTSHVQPIK LARVTKVLGR TGSQGQCTQV RVEFMDDTSR SIIRNVKGPV REGDVLTLLE SEREARRLR

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Macromolecule #34: uS14

MacromoleculeName: uS14 / type: protein_or_peptide / ID: 34 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 6.559625 KDa
SequenceString:
GHQQLYWSHP RKFGQGSRSC RVCSNRHGLI RKYGLNMCRQ CFRQYAKDIG FIKLD

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Macromolecule #35: 40S ribosomal protein S30

MacromoleculeName: 40S ribosomal protein S30 / type: protein_or_peptide / ID: 35 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 14.498884 KDa
SequenceString:
MQLFVRAQEL HTLEVTGRET VAQIKAHVAS LEGIAPEDQV VLLAGTPLED EATLGQCGVE ALSTLEVAGR MLGGKVHGSL ARVGKVRGQ TLKVAKQEKK KKRTGRAKRR MQYNRRFVNV VPTFGKKKGP NANS

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Macromolecule #36: eS31

MacromoleculeName: eS31 / type: protein_or_peptide / ID: 36 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 7.98644 KDa
SequenceString:
KSYTTPKKNK HKRKKVKLAV LKYYKVDENG KISRLRRECP SDECGAGVFM ASHFDRHYCG KCCLTYCF

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Macromolecule #37: ribosomal protein RACK1

MacromoleculeName: ribosomal protein RACK1 / type: protein_or_peptide / ID: 37 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 34.669113 KDa
SequenceString: TEQMTLRGTL KGHNGWVTQI ATTPQFPDMI LSASRDKTII MWKLTRDETN YGIPQRALRG HSHFVSDVVI SSDGQFALSG SWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI VSGSRDKTIK LWNTLGVCKY TVQDESHSEW VSCVRFSPNS S NPIIVSCG ...String:
TEQMTLRGTL KGHNGWVTQI ATTPQFPDMI LSASRDKTII MWKLTRDETN YGIPQRALRG HSHFVSDVVI SSDGQFALSG SWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI VSGSRDKTIK LWNTLGVCKY TVQDESHSEW VSCVRFSPNS S NPIIVSCG WDKLVKVWNL ANCKLKTNHI GHTGYLNTVT VSPDGSLCAS GGKDGQAMLW DLNEGKHLYT LDGGDIINAL CF SPNRYWL CAATGPSIKI WDLEGKIIVD ELKQEVISTS SKAEPPQCTS LAWSADGQTL FAGYTDNLVR VWQVTI

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Macromolecule #38: L8

MacromoleculeName: L8 / type: protein_or_peptide / ID: 38 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 26.840457 KDa
SequenceString: GRVIRGQRKG AGSVFRAHVK HRKGAARLRA VDFAERHGYI KGIVKDIIHD PGRGAPLAKV VFRDPYRFKK RTELFIAAEG IHTGQFVYC GKKAQLNIGN VLPVGTMPEG TIVCCLEEKP GDRGKLARAS GNYATVISHN PETKKTRVKL PSGSKKVISS A NRAVVGVV ...String:
GRVIRGQRKG AGSVFRAHVK HRKGAARLRA VDFAERHGYI KGIVKDIIHD PGRGAPLAKV VFRDPYRFKK RTELFIAAEG IHTGQFVYC GKKAQLNIGN VLPVGTMPEG TIVCCLEEKP GDRGKLARAS GNYATVISHN PETKKTRVKL PSGSKKVISS A NRAVVGVV AGGGRIDKPI LKAGRAYHKY KAKRNCWPRV RGVAMNPVEH PFGGGNHQHI GKPSTIRRDA PAGRKVGLIA AR RTGRLR

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Macromolecule #39: uL3

MacromoleculeName: uL3 / type: protein_or_peptide / ID: 39 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 46.107977 KDa
SequenceString: MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGI VGYVETPRGL RTFKTVFAEH ISDECKRRFY KNWHKSKKKA FTKYCKKWQD DAGKRQLDKD FSSMKKYCQV I RVLAHTQM ...String:
MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGI VGYVETPRGL RTFKTVFAEH ISDECKRRFY KNWHKSKKKA FTKYCKKWQD DAGKRQLDKD FSSMKKYCQV I RVLAHTQM RLLPLRQKKA HLMEIQVNGG TVAEKLDWAR ERLEQQVPVS QVFGQDEMID VIGVTKGKGY KGVTSRWHTK KL PRKTHRG LRKVACIGAW HPARVAFSVA RAGQKGYHHR TEINKKIYKI GQGYLIKDGK LIKNNASTDY DLSDKSINPL GGF VHYGEV TNDFVMLKGC VVGTKKRVLT LRKSLLVQTK RRALEKIDLK FIDTTSKFGH GRFQTVEEKK AFMGPLKKDR IAKE EGA

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Macromolecule #40: uL4

MacromoleculeName: uL4 / type: protein_or_peptide / ID: 40 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 47.727559 KDa
SequenceString: MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH QTSAESWGTG RAVARIPRVR GGGTHRSGQ GAFGNMCRGG RMFAPTKTWR RWHRRVNTTQ KRYAICSALA ASALPALVMS KGHRIEEVPE LPLVVEDKVE G YKKTKEAV ...String:
MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH QTSAESWGTG RAVARIPRVR GGGTHRSGQ GAFGNMCRGG RMFAPTKTWR RWHRRVNTTQ KRYAICSALA ASALPALVMS KGHRIEEVPE LPLVVEDKVE G YKKTKEAV LLLKKLKAWN DIKKVYASQR MRAGKGKMRN RRRIQRRGPC VIYNEDNGIV KAFRNIPGIT LLNVTKLNIL KL APGGHVG RFCIWTESAF RKLDDLYGTW RKAASLKSNY NLPMHKMLNT DLSRILKSPE IQRALRAPRK KIHRRVLKKN PLK NLRIML KLNPYAKTMR RNTILRQARN HKLRVERAAA ALAAKSDPKE APAKKKPVVG KKVKKPRAVG IKQKKKPVVG RKAA AAKKP AADKKAADKR AGPEDKKPAA

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Macromolecule #41: 60S ribosomal protein L5

MacromoleculeName: 60S ribosomal protein L5 / type: protein_or_peptide / ID: 41 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 34.481828 KDa
SequenceString: MGFVKVVKNK AYFKRYQVKF RRRREGKTDY YARKRLVIQD KNKYNTPKYR MIVRVTNRDI ICQIAYARIE GDMIVCAAYA HELPKYGVK VGLTNYAAAY CTGLLLARRL LNRFGMDKIY EGQVEVTGDE YNVESIDGQP GAFTCYLDAG LARTTTGNKV F GALKGAVD ...String:
MGFVKVVKNK AYFKRYQVKF RRRREGKTDY YARKRLVIQD KNKYNTPKYR MIVRVTNRDI ICQIAYARIE GDMIVCAAYA HELPKYGVK VGLTNYAAAY CTGLLLARRL LNRFGMDKIY EGQVEVTGDE YNVESIDGQP GAFTCYLDAG LARTTTGNKV F GALKGAVD GGLSIPHSTK RFPGYDSESK EFNAEVHRKH IMGQNVADYM RYLMEEDEDA YKKQFSQYIK NNVTPDMMEE MY KKAHAAI RENPVYEKKP KREVKKKRWN RPKMSLAQKK DRVAQKKASF LRAQERAAES

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Macromolecule #42: 60S ribosomal protein L6

MacromoleculeName: 60S ribosomal protein L6 / type: protein_or_peptide / ID: 42 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 33.028336 KDa
SequenceString: MAGEKAPAAK PDATKKSPAK KADHARGKAK KKTLAEKKPK KGKPHCSRNP VLVRGIGRYS RSAMYSRKAL YKRKYAAPKS RIERKKKRE KVLATVTKPV GGDKNGGTRV VKLRKMPRYY PTEDVPRKLL SHGKKPFSQH VRKLRASITP GTILIILTGR H RGKRVVFL ...String:
MAGEKAPAAK PDATKKSPAK KADHARGKAK KKTLAEKKPK KGKPHCSRNP VLVRGIGRYS RSAMYSRKAL YKRKYAAPKS RIERKKKRE KVLATVTKPV GGDKNGGTRV VKLRKMPRYY PTEDVPRKLL SHGKKPFSQH VRKLRASITP GTILIILTGR H RGKRVVFL KQLSSGLLLV TGPLSLNRVP LRRTHQKFVI ATSTKIDISG VKIPKHLTDA YFKKKKLRKP RHQEGEIFDT EK EKYEITE QRKVDQKAVD SQILPKIKAV PQLQGYLRSV FALTNGVYPH KLVF

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Macromolecule #43: uL30

MacromoleculeName: uL30 / type: protein_or_peptide / ID: 43 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 29.51425 KDa
SequenceString: LFANNIREKK KVPAVPETLK KKRRNFAELK IKRLRKKFAQ KMLRKARRKL IYEKAKHYHK EYRQMYRTEI RMARMARKAG NFYVPAEPK LAFVIRIRGI NGVSPKVRKV LQLLRLRQIF NGTFVKLNKA SINMLRIVEP YIAWGYPNLK SVNELIYKRG Y GKINKKRI ...String:
LFANNIREKK KVPAVPETLK KKRRNFAELK IKRLRKKFAQ KMLRKARRKL IYEKAKHYHK EYRQMYRTEI RMARMARKAG NFYVPAEPK LAFVIRIRGI NGVSPKVRKV LQLLRLRQIF NGTFVKLNKA SINMLRIVEP YIAWGYPNLK SVNELIYKRG Y GKINKKRI ALTDNTLIAR SLGKYNIICM EDLIHEIYTV GKHFKEANNF LWPFKLSSPR GGMKKKTTHF VEGGDAGNRE DQ INRLIRR MN

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Macromolecule #44: L7a

MacromoleculeName: L7a / type: protein_or_peptide / ID: 44 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 27.480555 KDa
SequenceString: KVVNPLFEKR PKNFGIGQDI QPKRDLTRFV KWPRYIRLQR QRAILYKRLK VPPAINQFTQ VLDRQTATQL LKLAHKYRPE TKQEKKQRL LARAEKKAAG KGDVPTKRPP VLRAGVNTVT TLVENKKAQL VVIAHDVDPI ELVVFLPALC RKMGVPYCIL K GKARLGRL ...String:
KVVNPLFEKR PKNFGIGQDI QPKRDLTRFV KWPRYIRLQR QRAILYKRLK VPPAINQFTQ VLDRQTATQL LKLAHKYRPE TKQEKKQRL LARAEKKAAG KGDVPTKRPP VLRAGVNTVT TLVENKKAQL VVIAHDVDPI ELVVFLPALC RKMGVPYCIL K GKARLGRL VHRKTCTTVA FTQVNSEDKG ALAKLVEAIR TNYNDRYDEI RRHWGGNVLG PKSVARIAKL EKAKAKELAT KL G

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Macromolecule #45: L9

MacromoleculeName: L9 / type: protein_or_peptide / ID: 45 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 21.627215 KDa
SequenceString:
MKTILSNQTV DIPENVDISL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW WGNRKELATV RTICSHVQNM IKGVTLGFR YKMRSVYAHF PINVVIQENG SLVEIRNFLG EKYIRRVRMR PGVACSVSQA QKDELVLEGN DIELVSNSAA L IQQATTVK NKDIRKFLDG IYVSEKGTVQ QA

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Macromolecule #46: 60S ribosomal protein L10

MacromoleculeName: 60S ribosomal protein L10 / type: protein_or_peptide / ID: 46 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 24.643057 KDa
SequenceString: MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRV RLHPFHVIRI NKMLSCAGAD RLQTGMRGAF GKPQGTVARV HIGQVIMSIR TKLQNKEHVV EALRRAKFKF P GRQKIHIS ...String:
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRV RLHPFHVIRI NKMLSCAGAD RLQTGMRGAF GKPQGTVARV HIGQVIMSIR TKLQNKEHVV EALRRAKFKF P GRQKIHIS KKWGFTKFNA DEFEDMVAEK RLIPDGCGVK YIPNRGPLDK WRALHS

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Macromolecule #47: 60S ribosomal protein L11

MacromoleculeName: 60S ribosomal protein L11 / type: protein_or_peptide / ID: 47 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 20.670904 KDa
SequenceString:
MAQRPQDQGE KENPMRELRI RKLCLNICVG ESGDRLTRAA KVLEQLTGQT PVFSKARYTV RSFGIRRNEK IAVHCTVRGA KAEEILEKG LKVREYELRK NNFSDTGNFG FGIQEHIDLG IKYDPSIGIY GLDFYVVLGR PGFSIADKKR RTGCIGAKHR I SKEEAMRW FQQKYDGIIL PGK

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Macromolecule #48: L13

MacromoleculeName: L13 / type: protein_or_peptide / ID: 48 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 24.331723 KDa
SequenceString: MAPSRNGMIL KPHFHKDWQR RVATWFNQPA RKIRRRKARQ ARARRIAPRP AAGPIRPIVR CPTVRYHTKV RAGRGFSLEE LRVAGIHKK VARTIGISVD PRRRNKSTES LQANVQRLKE YRSKLVLFPR KPSAPKKGDS SAEELKLATQ LTGPVMPIRN V FKKEKARV ...String:
MAPSRNGMIL KPHFHKDWQR RVATWFNQPA RKIRRRKARQ ARARRIAPRP AAGPIRPIVR CPTVRYHTKV RAGRGFSLEE LRVAGIHKK VARTIGISVD PRRRNKSTES LQANVQRLKE YRSKLVLFPR KPSAPKKGDS SAEELKLATQ LTGPVMPIRN V FKKEKARV ITEEEKNFKA FASLRMARAN ARLFGIRAKR AKEAAEQDVE KKK

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Macromolecule #49: Ribosomal protein L14

MacromoleculeName: Ribosomal protein L14 / type: protein_or_peptide / ID: 49 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 23.870549 KDa
SequenceString: MVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTRVRRQAM PFKCMQLTDF ILKFPHSARQ KYVRKAWEKA DINTKWAAT RWAKKIEARE RKAKMTDFDR YKVMKAKKMR NRIIKNEVKK LQRAALLKAS PKKAPVAKGA VAAAAAAAKV P AKKATAAG ...String:
MVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTRVRRQAM PFKCMQLTDF ILKFPHSARQ KYVRKAWEKA DINTKWAAT RWAKKIEARE RKAKMTDFDR YKVMKAKKMR NRIIKNEVKK LQRAALLKAS PKKAPVAKGA VAAAAAAAKV P AKKATAAG KKAAAQKAPA QKAPAQKAAG QKAAQPPKAQ KGQKPPAQKA PAPKASGKKA

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Macromolecule #50: Ribosomal protein L15

MacromoleculeName: Ribosomal protein L15 / type: protein_or_peptide / ID: 50 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 24.076088 KDa
SequenceString: GAYKYIQELW RKKQSDVMRF LLRVRCWQYR QLSALHRAPR PTRPDKARRL GYKAKQGYVI YRIRVRRGGR KRPVPKGATY GKPVHHGVN QLKFARSLQS VAEERAGRHC GALRVLNSYW VGEDSTYKFF EVILIDPFHK AIRRNPDTQW ITKPVHKHRE M RGLTSAGR ...String:
GAYKYIQELW RKKQSDVMRF LLRVRCWQYR QLSALHRAPR PTRPDKARRL GYKAKQGYVI YRIRVRRGGR KRPVPKGATY GKPVHHGVN QLKFARSLQS VAEERAGRHC GALRVLNSYW VGEDSTYKFF EVILIDPFHK AIRRNPDTQW ITKPVHKHRE M RGLTSAGR KSRGLGKGHK FHHTIGGSRR AAWRRRNTLQ LHRYR

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Macromolecule #51: 60S RIBOSOMAL PROTEIN UL13

MacromoleculeName: 60S RIBOSOMAL PROTEIN UL13 / type: protein_or_peptide / ID: 51 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 23.533299 KDa
SequenceString: MAEGQVLVLD GRGHLLGRLA AIVAKQVLLG RKVVVVRCEG INISGNFYRN KLKYLAFLRK RMNTNPSRGP YHFRAPSRIF WRTVRGMLP HKTKRGQAAL DRLKVFDGIP PPYDKKKRMV VPAALKVVRL KPTRKFAYLG RLAHEVGWKY QAVTATLEEK R KEKAKIHY ...String:
MAEGQVLVLD GRGHLLGRLA AIVAKQVLLG RKVVVVRCEG INISGNFYRN KLKYLAFLRK RMNTNPSRGP YHFRAPSRIF WRTVRGMLP HKTKRGQAAL DRLKVFDGIP PPYDKKKRMV VPAALKVVRL KPTRKFAYLG RLAHEVGWKY QAVTATLEEK R KEKAKIHY RKKKQLMRLR KQAEKNVEKK ISKFTDVLKT HGLLV

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Macromolecule #52: uL22

MacromoleculeName: uL22 / type: protein_or_peptide / ID: 52 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 23.056182 KDa
SequenceString: MRKALPVSGQ RSPAKMVRYS LDPENPTKSC KSRGSNLRVH FKNTRETAQA IKGMHIRKAT KYLKDVTLKK QCVPFRRYNG GVGRCAQAK QWGWTQGRWP KKSAEFLLHM LKNAESNAEL KGLDVDSLVI EHIQVNKAPK MRRRTYRAHG RINPYMSSPC H IEMILTEK ...String:
MRKALPVSGQ RSPAKMVRYS LDPENPTKSC KSRGSNLRVH FKNTRETAQA IKGMHIRKAT KYLKDVTLKK QCVPFRRYNG GVGRCAQAK QWGWTQGRWP KKSAEFLLHM LKNAESNAEL KGLDVDSLVI EHIQVNKAPK MRRRTYRAHG RINPYMSSPC H IEMILTEK EQIVPKPEEE VAQKKKISQK KLKKQKLMAR E

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Macromolecule #53: L18

MacromoleculeName: L18 / type: protein_or_peptide / ID: 53 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 21.699688 KDa
SequenceString:
MGVDIRHNKD RKVRRKEPKS QDIYLRLLVK LYRFLARRTN STFNQVVLKR LFMSRTNRPP LSLSRMIRKM KLPGRENKTA VVVGTVTDD VRVQEVPKLK VCALRVTSRA RSRILKAGGK ILTFDQLALD SPKGRGTVLL SGPRKGREVY RHFGKAPGTP H SHTKPYVR SKGRKFERAR GRRASRGYKN

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Macromolecule #54: 60S ribosomal protein L19

MacromoleculeName: 60S ribosomal protein L19 / type: protein_or_peptide / ID: 54 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 23.535281 KDa
SequenceString: MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARM PEKVTWMRRM RILRRLLRRY RESKKIDRHM YHSLYLKVKG NVFKNKRILM EHIHKLKADK ARKKLLADQA E ARRSKTKE ...String:
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARM PEKVTWMRRM RILRRLLRRY RESKKIDRHM YHSLYLKVKG NVFKNKRILM EHIHKLKADK ARKKLLADQA E ARRSKTKE ARKRREERLQ AKKEEIIKTL SKEEETKK

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Macromolecule #55: 60S ribosomal protein L18a

MacromoleculeName: 60S ribosomal protein L18a / type: protein_or_peptide / ID: 55 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 20.827561 KDa
SequenceString:
MKASGTLREY KVVGRCLPTP KCRTPPLYRM RIFAPNHVVA KSRFWYFVSQ LKKMKKSSGE IVYCGQVFEK SPLRVKNFGI WLRYDSRSG THNMYREYRD LTTAGAVTQC YRDMGARHRA RAHSIQIMKV EEIAASKCRR PAVKQFHDSK IKFPLPHRVL R RQHKPRFT TKRPNTFF

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Macromolecule #56: eL21

MacromoleculeName: eL21 / type: protein_or_peptide / ID: 56 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 18.478791 KDa
SequenceString:
TNTKGKRRGT RYMFSRPFRK HGVVPLATYM RIYKKGDIVD IKGMGTVQKG MPHKCYHGKT GRVYNVTQHA VGIVVNKQVK GKILAKRIN VRIEHIKHSK SRDSFLKRVK ENDQKKKEAK EKGTWVQLKR QPAPPREAHF VRTNGKEPEL LEPIPYEFMA

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Macromolecule #57: L22

MacromoleculeName: L22 / type: protein_or_peptide / ID: 57 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 14.798989 KDa
SequenceString:
MAPVKKLVAK GGKKKKQLLK FTLDCTHPVE DGIMDAANFE QFLQERIKVN GKAGNLGGGV VSLERSKSKI TVTSEVPFSK RYLKYLTKK YLKKNNLRDW LRVVANTKES YELRYFQINQ DEEEEEDED

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Macromolecule #58: eL14

MacromoleculeName: eL14 / type: protein_or_peptide / ID: 58 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 13.972425 KDa
SequenceString:
SGAKFRISLG LPVGAVINCA DNTGAKNLYI ISVKGIKGRL NRLPAAGVGD MVMATVKKGK PELRKKVHPA VVIRQRKSYR RKDGVFLYF EDNAGVIVNN KGEMKGSAIT GPVAKECADL WPRIASNAGS IA

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Macromolecule #59: uL23

MacromoleculeName: uL23 / type: protein_or_peptide / ID: 59 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 17.768246 KDa
SequenceString:
MAPKAKKEAP APPKVEAKAK ALKAKKAVLK GVHSHKKKKI RTSPTFRRPK TLRLRRQPKY PRKSAPRRNK LDHYAIIKFP LTTESAMKK IEDNNTLVFI VDVKANKHQI KQAVKKLYDI DVAKVNTLIR PDGEKKAYVR LAPDYDALDV ANKIGII

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Macromolecule #60: Ribosomal protein L26

MacromoleculeName: Ribosomal protein L26 / type: protein_or_peptide / ID: 60 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 15.705556 KDa
SequenceString:
MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG HYKGQQIGKV VQVYRKKYVI YIERVQREK ANGTTVHVGI HPSKVVITRL KLDKDRKKIL ERKAKSRQVG KEK

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Macromolecule #61: 60S ribosomal protein L27

MacromoleculeName: 60S ribosomal protein L27 / type: protein_or_peptide / ID: 61 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 15.704635 KDa
SequenceString:
GKFMKPGKVV LVLAGRYSGR KAVIVKNIDD GTSDRPYSHA LVAGIDRYPR KVTAAMGKKK IAKRSKIKSF VKVYNYNHLM PTRYSVDIP LDKTVVNKDV FRDPALKRKA RREAKVKFEE RYKTGKNKWF FQKLRF

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Macromolecule #62: uL15

MacromoleculeName: uL15 / type: protein_or_peptide / ID: 62 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 17.831941 KDa
SequenceString:
MVAAKCQHRG GAEPSRLRKT RKLRGHVSHG HGRIGKHRKH PGGRGNAGGM HHHRINFDKY HPGYFGKVGM RHYHLKRNQS FCPTVNLDK LWTLVSEQTR VNAAKNKTGA APIIDVVRSG YYKVLGKGKL PKQPVIVKAK FFSRRAEEKI KGVGGACVLV A

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Macromolecule #63: eL29

MacromoleculeName: eL29 / type: protein_or_peptide / ID: 63 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 26.708707 KDa
SequenceString: MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN NAKAMAARAE AIKALVKPKE VKPTIPKGV SRKLHRLAYI AHPKLGRRAR ARIARGLRLS RPQTKAKAKT EPQIKGKVKA QIKAQAQAQI KSKGKGKAQA E TKPKAQAE ...String:
MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN NAKAMAARAE AIKALVKPKE VKPTIPKGV SRKLHRLAYI AHPKLGRRAR ARIARGLRLS RPQTKAKAKT EPQIKGKVKA QIKAQAQAQI KSKGKGKAQA E TKPKAQAE TKPKAQAQAK PKAQAQGKPK AQAQGKPKAQ AQAKPKAQAQ AKPKAQAQTK PKAQATPAAP VPAQAPPKGA QP PAKAP

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Macromolecule #64: eL30

MacromoleculeName: eL30 / type: protein_or_peptide / ID: 64 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 12.807065 KDa
SequenceString:
MVAAKKTKKS LESINSRLQL VMKSGKYVLG YKQSLKMIRQ GKAKLVILAN NCPALRKSEI EYYAMLAKTG VHHYSGNNIE LGTACGKYY RVCTLSIIDP GDSDIIRSMP EQTGEK

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Macromolecule #65: eL31

MacromoleculeName: eL31 / type: protein_or_peptide / ID: 65 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 12.635694 KDa
SequenceString:
NEVVTREYTI NIHKRIHGVG FKKRAPRALK EIRKFAMKEM GTPDVRIDTR LNKAVWAKGI RNVPYRIRVR LSRKRNEDED SPNKLYTLV TYVPVTTFKN LQTVNVDE

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Macromolecule #66: eL32

MacromoleculeName: eL32 / type: protein_or_peptide / ID: 66 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 15.022021 KDa
SequenceString:
AALRPLVKPK IVKKRTKKFI RHQSDRYVKI KRNWRKPRGI DNRVRRRFKG QILMPNIGYG SNKKTKHMLP SGFRKFLVHN VKELEVLLM CNKSYCAEIA HNVSSKNRKA IVERAAQLAI RVTNPNARL

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Macromolecule #67: eL33

MacromoleculeName: eL33 / type: protein_or_peptide / ID: 67 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 12.449612 KDa
SequenceString:
SGRLWCKAIF AGYKRGLRNQ REHTALLKIE GVYARDETEF YLGKRCAYVY KAKNNTVTPG GKPNKTRVIW GKVTRAHGNS GMVRAKFRS NLPAKAIGHR IRVMLYPSRI

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Macromolecule #68: 60S ribosomal protein L34

MacromoleculeName: 60S ribosomal protein L34 / type: protein_or_peptide / ID: 68 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 14.210088 KDa
SequenceString:
LPGRCLEAAT MVQRLTYRRR LSYNTASNKT RLSRTPGNRI VYLYTKKVGK APKSACGVCP GRLRGVRAVR PKVLMRLSKT KKHVSRAYG GSMCAKCVRD RIKRAFLIEE QKIVVKVLKA QAQSQKA

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Macromolecule #69: uL29

MacromoleculeName: uL29 / type: protein_or_peptide / ID: 69 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 14.435403 KDa
SequenceString:
AKIKARDLRG KKKEELLKQL DDLKVELSQL RVAKVTGGAA SKLSKIRVVR KSIARVLTVI NQTQKENLRK FYKGKKYKPL DLRPKKTRA MRRRLNKHEE SLKTKKQQRK ERLYPLRKYA VKA

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Macromolecule #70: 60S ribosomal protein L36

MacromoleculeName: 60S ribosomal protein L36 / type: protein_or_peptide / ID: 70 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 13.546292 KDa
SequenceString:
MGFRPGRHRK AAATALRYPM AVGLNKGHKV TKNVSKPRHS RRRGRLTKHT KFVRDMIREV CGFAPYERRA MELLKVSKDK RALKFIKKR VGTHIRAKRK REELSSVLAA MRKAAAKD

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Macromolecule #71: Ribosomal protein L37

MacromoleculeName: Ribosomal protein L37 / type: protein_or_peptide / ID: 71 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 11.111032 KDa
SequenceString:
MTKGTSSFGK RRNKTHTLCR RCGSKAYHLQ KSTCGKCGYP AKRKRKYNWS AKAKRRNTTG TGRMRHLKIV YRRFRHGFRE GTTPKPKRA AVAASSSS

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Macromolecule #72: L38

MacromoleculeName: L38 / type: protein_or_peptide / ID: 72 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 8.107752 KDa
SequenceString:
PRKIEEIKDF LLTARRKDAK SVKIKKNKDN VKFKVRCSRY LYTLVITDKE KAEKLKQSLP PGLAVKELK

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Macromolecule #73: eL39

MacromoleculeName: eL39 / type: protein_or_peptide / ID: 73 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 6.324579 KDa
SequenceString:
SSHKTFRIKR FLAKKQKQNR PIPQWIWMKT GNKIRYNSKR RHWRRTKLGL

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Macromolecule #74: 60S RIBOSOMAL PROTEIN EL40

MacromoleculeName: 60S RIBOSOMAL PROTEIN EL40 / type: protein_or_peptide / ID: 74 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 14.69531 KDa
SequenceString:
MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGLTLSDYN IQKESTLHLV LRLHGGIIEP SLRQLAQKY NCDKMICRKC YARLHPRAVN CRKKKCGHTN NLRPKKKVK

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Macromolecule #75: 60s ribosomal protein l41

MacromoleculeName: 60s ribosomal protein l41 / type: protein_or_peptide / ID: 75 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 3.473451 KDa
SequenceString:
MRAKWRKKRM RRLKRKRRKM RQRSK

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Macromolecule #76: eL42

MacromoleculeName: eL42 / type: protein_or_peptide / ID: 76 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 16.170214 KDa
SequenceString:
MVAVSHGSEE VHSGTAYKLP LLL(UNK)PLSFRA ASAPANMVNV PKTRRTFCKK CGKHQPHKVT QYKKGKDSLY AQGKRR YDR KQSGYGGQTK PIFRKKAKTT KKIVLRLECV EPNCRSKRML AIKRCKHFEL GGDKKRKGQV IQF

+
Macromolecule #77: ribosomal protein eL43

MacromoleculeName: ribosomal protein eL43 / type: protein_or_peptide / ID: 77 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 12.010391 KDa
SequenceString:
MRIASLPLRA LGLGSGDMAK RTKKVGIVGK YGTRYGASLR KMVKKIEISQ HAKYTCSFCG KTKMKRRAVG IWHCGSCMKT VAGGAWTYN TTSAVTVKSA IRRLKELKDQ

+
Macromolecule #78: eL28

MacromoleculeName: eL28 / type: protein_or_peptide / ID: 78 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 15.783614 KDa
SequenceString:
MSAHLQWMVV RNCSSFLIKR NKQTYSTEPN NLKARNSFRY NGLIHRKTVG VEPAADGKGV VVVMKRRSGQ RKPATSYVRT TINKNARAT LSSIRHMIRK NKYHPDLRMA AIRRASAILR SQKPVMVKRK RTRPTKSS

+
Macromolecule #80: 60S acidic ribosomal protein P0

MacromoleculeName: 60S acidic ribosomal protein P0 / type: protein_or_peptide / ID: 80 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 34.380504 KDa
SequenceString: MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK AVVLMGKNTM MRKAIRGHLE NNPALEKLLP HIRGNVGFV FTKEDLTEIR DMLLANKVPA AARAGAIAPC EVTVPAQNTG LGPEKTSFFQ ALGITTKISR GTIEILSDVQ L IKTGDKVG ...String:
MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK AVVLMGKNTM MRKAIRGHLE NNPALEKLLP HIRGNVGFV FTKEDLTEIR DMLLANKVPA AARAGAIAPC EVTVPAQNTG LGPEKTSFFQ ALGITTKISR GTIEILSDVQ L IKTGDKVG ASEATLLNML NISPFSFGLI IQQVFDNGSI YNPEVLDITE DTLHSRFLEG VRNVASVCLQ IGYPTVASVP HS IINGYKR VLALSVETEY TFPLAEKVKA FLADPSAFVA AAPVAAASTA APAAAAAAPA KVEAKEESEE SDEDMGFGLF D

+
Macromolecule #81: uL12

MacromoleculeName: uL12 / type: protein_or_peptide / ID: 81 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 21.29559 KDa
SequenceString: AFRYSARRRP RCNSLRSSRI RVHPTPGAST MPPKFDPNEI KVVYLRCTGG EVGATSALAP KIGPLGLSPK KVGDDIAKAT GDWKGLRIT VKLTIQNRQA QIEVVPSASA LIIKALKEPP RDRKKQKNIK HSGNITFDEI VNIARQMRHR SLARELSGTI K EILGTAQS ...String:
AFRYSARRRP RCNSLRSSRI RVHPTPGAST MPPKFDPNEI KVVYLRCTGG EVGATSALAP KIGPLGLSPK KVGDDIAKAT GDWKGLRIT VKLTIQNRQA QIEVVPSASA LIIKALKEPP RDRKKQKNIK HSGNITFDEI VNIARQMRHR SLARELSGTI K EILGTAQS VGCNVDGRHP HDIIDDINSG AVECPAS

+
Macromolecule #84: Ribosomal protein

MacromoleculeName: Ribosomal protein / type: protein_or_peptide / ID: 84 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 24.879422 KDa
SequenceString: MSSKVSRDTL YEAVREVLHG NQRKRRKFLE TVELQISLKN YDPQKDKRFS GTVRLKSTPR PKFSVCVLGD QQHCDEAKAV DIPHMDIEA LKKLNKNKKL VKKLAKKYDA FLASESLIKQ IPRILGPGLN KAGKFPSLLT HNENMVAKVD EVKSTIKFQM K KVLCLAVA ...String:
MSSKVSRDTL YEAVREVLHG NQRKRRKFLE TVELQISLKN YDPQKDKRFS GTVRLKSTPR PKFSVCVLGD QQHCDEAKAV DIPHMDIEA LKKLNKNKKL VKKLAKKYDA FLASESLIKQ IPRILGPGLN KAGKFPSLLT HNENMVAKVD EVKSTIKFQM K KVLCLAVA VGHVKMTDDE LVYNIHLAVN FLVSLLKKNW QNVRALYIKS TMGKPQRLY

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Macromolecule #85: Sec61Beta

MacromoleculeName: Sec61Beta / type: protein_or_peptide / ID: 85 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 1.788032 KDa
SequenceString:
GMWRFYTEDS PGLKV

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Macromolecule #86: 60S ribosomal protein L24-like protein

MacromoleculeName: 60S ribosomal protein L24-like protein / type: protein_or_peptide / ID: 86 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Rabbit (rabbit)
Molecular weightTheoretical: 15.538256 KDa
SequenceString:
MKVELCSFSG YKIYPGHGRR YARTDGKVFQ FLNAKCESAF LSKRNPRQIN WTVLYRRKHK KGQSEEIQKK RTRRAVKFQR AITGASLAD IMAKRNQKPE VRKAQREQAI RAAKEAKKAK QASKKTAMAA AKEKR

+
Macromolecule #87: MAGNESIUM ION

MacromoleculeName: MAGNESIUM ION / type: ligand / ID: 87 / Number of copies: 299 / Formula: MG
Molecular weightTheoretical: 24.305 Da

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Macromolecule #88: BLASTICIDIN S

MacromoleculeName: BLASTICIDIN S / type: ligand / ID: 88 / Number of copies: 1 / Formula: BLS
Molecular weightTheoretical: 422.439 Da
Chemical component information

ChemComp-BLS:
BLASTICIDIN S / antibiotic*YM / Blasticidin S

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Macromolecule #89: ZINC ION

MacromoleculeName: ZINC ION / type: ligand / ID: 89 / Number of copies: 8 / Formula: ZN
Molecular weightTheoretical: 65.409 Da

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Experimental details

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Structure determination

Methodcryo EM
Processingsingle particle reconstruction
Aggregation stateparticle

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Sample preparation

Concentration0.63 mg/mL
BufferpH: 7.4
Details: 50 mM HEPES pH 7.4 100 mM KOAc 5 mM Mg(Oac)2 1mM DTT
GridModel: Quantifoil R2/2 / Material: COPPER / Mesh: 300 / Pretreatment - Type: GLOW DISCHARGE / Pretreatment - Time: 30 sec.
VitrificationCryogen name: ETHANE / Chamber humidity: 70 % / Chamber temperature: 288.15 K / Instrument: LEICA EM GP
Details: 30s sample incubation on grid followed by 1.1s blotting time..
Details165nM (OD260nm~10.5)

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Electron microscopy

MicroscopeFEI TECNAI ARCTICA
Electron beamAcceleration voltage: 200 kV / Electron source: FIELD EMISSION GUN
Electron opticsC2 aperture diameter: 100.0 µm / Calibrated defocus max: 2.0 µm / Calibrated defocus min: 0.4 µm / Calibrated magnification: 79000 / Illumination mode: FLOOD BEAM / Imaging mode: BRIGHT FIELDBright-field microscopy / Cs: 2.7 mm
Sample stageSpecimen holder model: FEI TITAN KRIOS AUTOGRID HOLDER / Cooling holder cryogen: NITROGEN
DetailsCollected in super-resolution mode (0.675A pixel size)
Image recordingFilm or detector model: GATAN K2 SUMMIT (4k x 4k) / Detector mode: SUPER-RESOLUTION / Number grids imaged: 1 / Number real images: 3500 / Average exposure time: 8.0 sec. / Average electron dose: 41.9 e/Å2
Experimental equipment
Model: Talos Arctica / Image courtesy: FEI Company

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Image processing

Particle selectionNumber selected: 730463
Initial angle assignmentType: MAXIMUM LIKELIHOOD
Final 3D classificationNumber classes: 5 / Software - Name: RELION (ver. 3.0)
Final angle assignmentType: MAXIMUM LIKELIHOOD
Final reconstructionNumber classes used: 1 / Resolution.type: BY AUTHOR / Resolution: 3.8 Å / Resolution method: FSC 0.143 CUT-OFF / Software - Name: RELION (ver. 3.0) / Number images used: 29879
FSC plot (resolution estimation)

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Atomic model buiding 1

Initial modelPDB ID:

6hcj

Output model

PDB-7nwg:
Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S.

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