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-Structure paper
Title | Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog. |
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Journal, issue, pages | Elife, Vol. 5, Year 2016 |
Publish date | Nov 8, 2016 (structure data deposition date) |
Authors | Volkov, O.A. / Kinch, L. / Ariagno, C. / Deng, X. / Zhong, S. / Grishin, N. / Tomchick, D.R. / Chen, Z. / Phillips, M.A. |
External links | Elife / PubMed:27977001 |
Methods | X-ray diffraction |
Resolution | 1.481 - 2.42 Å |
Structure data | PDB-5tvf: PDB-5tvm: PDB-5tvo: |
Chemicals | ChemComp-B3P: ChemComp-CGQ: ChemComp-PUT: ChemComp-HOH: ChemComp-PYR: ChemComp-NA: |
Source |
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Keywords | LYASE / AdoMetDC / CGP40215 / decarboxylase / allostery / pseudoenzyme / prozyme / autoinhibition / cis-proline |