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Showing all 34 items for (author: d. & t. & brown)

PDB-8blo:
Human Urea Transporter UT-A (N-Terminal Domain Model)
Method: single particle / : Chi G, Pike ACW, Maclean EM, Mukhopadhyay SMM, Bohstedt T, Scacioc A, Wang D, McKinley G, Fernandez-Cid A, Arrowsmith CH, Bountra C, Edwards A, Burgess-Brown NA, van Putte W, Duerr K

PDB-8blp:
Human Urea Transporter UT-B/UT1 in Complex with Inhibitor UTBinh-14
Method: single particle / : Chi G, Dietz L, Pike ACW, Maclean EM, Mukhopadhyay SMM, Bohstedt T, Wang D, Scacioc A, McKinley G, Arrowsmith CH, Edwards A, Bountra C, Fernandez-Cid A, Burgess-Brown NA, Duerr KL

PDB-7un1:
8-nm repeat of the human sperm tip singlet microtubule
Method: single particle / : Gui M, Croft JT, Zabeo D, Acharya V, Kollman JM, Burgoyne T, Hoog JL, Brown A

PDB-7ung:
48-nm repeat of the human respiratory doublet microtubule
Method: single particle / : Gui M, Croft JT, Zabeo D, Acharya V, Kollman JM, Burgoyne T, Hoog JL, Brown A

PDB-7tbj:
Composite structure of the human nuclear pore complex (NPC) symmetric core generated with a 12A cryo-ET map of the purified HeLa cell NPC
Method: subtomogram averaging / : Petrovic S, Samanta D, Perriches T, Bley CJ, Thierbach K, Brown B, Nie S, Mobbs GW, Stevens TA, Liu X, Tomaleri GP, Schaus L, Hoelz A

PDB-7tbl:
Composite structure of the human nuclear pore complex (NPC) cytoplasmic face generated with a 12A cryo-ET map of the purified HeLa cell NPC
Method: subtomogram averaging / : Bley CJ, Nie S, Mobbs GW, Petrovic S, Gres AT, Liu X, Mukherjee S, Harvey S, Huber FM, Lin DH, Brown B, Tang AW, Rundlet EJ, Correia AR, Chen S, Regmi SG, Stevens TA, Jette CA, Dasso M, Patke A, Palazzo AF, Kossiakoff AA, Hoelz A

PDB-7or0:
Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60, conformation 2
Method: single particle / : Grieben M, Pike ACW, Saward BG, Wang D, Mukhopadhyay SMM, Moreira T, Chalk R, MacLean EM, Marsden BD, Burgess-Brown NA, Bountra C, Schofield CJ, Carpenter EP

PDB-7or1:
Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60, conformation 1
Method: single particle / : Grieben M, Pike ACW, Saward BG, Wang D, Mukhopadhyay SMM, Moreira T, Chalk R, MacLean EM, Marsden BD, Burgess-Brown NA, Bountra C, Schofield CJ, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-7mvu:
Single particle cryo-EM structure of the Chaetomium thermophilum Nup192-Nic96 complex (Nup192 residues 1-1756; Nic96 residues 240-301)
Method: single particle / : Petrovic S, Samanta D, Perriches T, Bley CJ, Thierbach K, Brown B, Nie S, Mobbs GW, Stevens TA, Liu X, Tomaleri GP, Schaus L, Hoelz A

PDB-7mvv:
Single particle cryo-EM structure of the Chaetomium thermophilum Nup192-Nic96-Nup53-Nup145N complex (Nup192 residues 1-1756; Nic96 residues 240-301; Nup53 31-67; Nup145N 616-683)
Method: single particle / : Petrovic S, Samanta D, Perriches T, Bley CJ, Thierbach K, Brown B, Nie S, Mobbs GW, Stevens TA, Liu X, Tomaleri GP, Schaus L, Hoelz A

PDB-7mvy:
Single particle cryo-EM structure of the Chaetomium thermophilum Nup188-Nic96 complex (Nup188 residues 1-1858; Nic96 residues 240-301)
Method: single particle / : Petrovic S, Samanta D, Perriches T, Bley CJ, Thierbach K, Brown B, Nie S, Mobbs GW, Stevens TA, Liu X, Tomaleri GP, Schaus L, Hoelz A

PDB-7mvz:
Single particle cryo-EM structure of the Chaetomium thermophilum Nup188-Nic96-Nup145N complex (Nup188 residues 1-1858; Nic96 residues 240-301; Nup145N residues 640-732)
Method: single particle / : Petrovic S, Samanta D, Perriches T, Bley CJ, Thierbach K, Brown B, Nie S, Mobbs GW, Stevens TA, Liu X, Tomaleri GP, Schaus L, Hoelz A

PDB-7tbi:
Composite structure of the S. cerevisiae nuclear pore complex (NPC)
Method: subtomogram averaging / : Petrovic S, Samanta D, Perriches T, Bley CJ, Thierbach K, Brown B, Nie S, Mobbs GW, Stevens TA, Liu X, Tomaleri GP, Schaus L, Hoelz A

PDB-7tbk:
Composite structure of the dilated human nuclear pore complex (NPC) symmetric core generated with a 37A in situ cryo-ET map of CD4+ T cell NPC
Method: subtomogram averaging / : Petrovic S, Samanta D, Perriches T, Bley CJ, Thierbach K, Brown B, Nie S, Mobbs GW, Stevens TA, Liu X, Tomaleri GP, Schaus L, Hoelz A

PDB-7tbm:
Composite structure of the dilated human nuclear pore complex (NPC) generated with a 37A in situ cryo-ET map of CD4+ T cell NPC
Method: subtomogram averaging / : Bley CJ, Nie S, Mobbs GW, Petrovic S, Gres AT, Liu X, Mukherjee S, Harvey S, Huber FM, Lin DH, Brown B, Tang AW, Rundlet EJ, Correia AR, Chen S, Regmi SG, Stevens TA, Jette CA, Dasso M, Patke A, Palazzo AF, Kossiakoff AA, Hoelz A

PDB-7ra3:
cryo-EM of human Gastric inhibitory polypeptide receptor GIPR bound to GIP
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7rbt:
cryo-EM structure of human Gastric inhibitory polypeptide receptor GIPR bound to tirzepatide
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7rg9:
cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R in apo form
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7rgp:
cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R bound to tirzepatide
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7oqz:
Cryo-EM structure of human TMEM45A
Method: single particle / : Grieben M, Pike ACW, Evans A, Shrestha L, Venkaya S, Mukhopadhyay SMM, Moreira T, Chalk R, MacLean EM, Marsden BD, Burgess-Brown NA, Bountra C, Carpenter EP

PDB-7ain:
Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl (Reference Map)
Method: single particle / : Chi G, Man H, Ebenhoch R, Reggiano G, Pike ACW, Wang D, McKinley G, Mukhopadhyay SMM, MacLean EM, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Arrowsmith CH, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, DiMaio F, Duerr KL, Structural Genomics Consortium (SGC)

PDB-7aio:
Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl (Subclass)
Method: single particle / : Chi G, Man H, Ebenhoch R, Reggiano G, Pike ACW, Wang D, McKinley G, Mukhopadhyay SMM, MacLean EM, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Arrowsmith CH, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, DiMaio F, Duerr KL, Structural Genomics Consortium (SGC)

PDB-7aiq:
Structure of Human Potassium Chloride Transporter KCC1 in NaCl (Subclass 1)
Method: single particle / : Ebenhoch R, Chi G, Man H, Wang D, McKinley G, Mukhopadhyay SMM, MacLean EM, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Liko I, Tehan BG, Almeida FG, Arrowsmith CH, Tang H, Robinson CV, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, Duerr KL, Structural Genomics Consortium (SGC)

PDB-7air:
Structure of Human Potassium Chloride Transporter KCC1 in NaCl (Subclass 2)
Method: single particle / : Ebenhoch R, Chi G, Man H, Wang D, McKinley G, Mukhopadhyay SMM, MacLean EM, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Liko I, Tehan BG, Almeida FG, Arrowsmith CH, Tang H, Robinson CV, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, Duerr KL, Structural Genomics Consortium (SGC)

PDB-7a5v:
CryoEM structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer, in complex with histamine and megabody Mb25 in lipid nanodisc
Method: single particle / : Nakane T, Kotecha A, Sente A, Yamashita K, McMullan G, Masiulis S, Brown PMGE, Grigoras IT, Malinauskaite L, Malinauskas T, Miehling J, Yu L, Karia D, Pechnikova EV, de Jong E, Keizer J, Bischoff M, McCormack J, Tiemeijer P, Hardwick SW, Chirgadze DY, Murshudov G, Aricescu AR, Scheres SHW

PDB-6y5v:
Structure of Human Potassium Chloride Transporter KCC3b (S45D/T940D/T997D) in KCl
Method: single particle / : Chi G, Man H, Ebenhoch R, Reggiano G, Pike ACW, Wang D, McKinley G, Mukhopadhyay SMM, MacLean EM, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Arrowsmith CH, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, DiMaio F, Duerr KL

PDB-6y5r:
Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl
Method: single particle / : Chi G, Man H, Ebenhoch R, Reggiano G, Pike ACW, Wang D, McKinley G, Mukhopadhyay SMM, MacLean B, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Arrowsmith CH, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, DiMaio F, Duerr KL, Structural Genomics Consortium (SGC)

PDB-5urf:
The structure of human bocavirus 1
Method: single particle / : Mietzsch M, Kailasan S, Garrison J, Ilyas M, Chipman P, Kandola K, Jansen M, Spear J, Sousa D, McKenna R, Soderlund-Venermo M, Baker T, Agbandje-McKenna M

PDB-3jca:
Core model of the Mouse Mammary Tumor Virus intasome
Method: single particle / : Lyumkis DL, Ballandras-Colas A, Brown M, Cook NJ, Dewdney TG, Demeler B, Cherepanov P, Engelman AN

PDB-4d3e:
Tetramer of IpaD, modified from 2J0O, fitted into negative stain electron microscopy reconstruction of the wild type tip complex from the type III secretion system of Shigella flexneri
Method: single particle / : Cheung M, Shen DK, Makino F, Kato T, Roehrich D, Martinez-Argudo I, Walker ML, Murillo I, Liu X, Pain M, Brown J, Frazer G, Mantell J, Mina P, Todd T, Sessions RB, Namba K, Blocker AJ

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

  • The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
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External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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