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Yorodumi- PDB-7or1: Cryo-EM structure of the human TRPA1 ion channel in complex with ... -
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-Basic information
Entry | Database: PDB / ID: 7or1 | |||||||||
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Title | Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60, conformation 1 | |||||||||
Components | Transient receptor potential cation channel subfamily A member 1 | |||||||||
Keywords | MEMBRANE PROTEIN / Transient receptor potential cation channel subfamily A member 1 / Structural Genomics / Structural Genomics Consortium / SGC | |||||||||
Function / homology | Function and homology information temperature-gated cation channel activity / stereocilium bundle / detection of chemical stimulus involved in sensory perception of pain / thermoception / TRP channels / channel activity / response to pain / cellular response to organic substance / intracellularly gated calcium channel activity / detection of mechanical stimulus involved in sensory perception of pain ...temperature-gated cation channel activity / stereocilium bundle / detection of chemical stimulus involved in sensory perception of pain / thermoception / TRP channels / channel activity / response to pain / cellular response to organic substance / intracellularly gated calcium channel activity / detection of mechanical stimulus involved in sensory perception of pain / monoatomic ion transport / sensory perception of pain / response to cold / response to organic substance / calcium ion transmembrane transport / calcium channel activity / intracellular calcium ion homeostasis / response to organic cyclic compound / cellular response to hydrogen peroxide / protein homotetramerization / cell surface receptor signaling pathway / response to xenobiotic stimulus / identical protein binding / plasma membrane Similarity search - Function | |||||||||
Biological species | Homo sapiens (human) | |||||||||
Method | ELECTRON MICROSCOPY / single particle reconstruction / cryo EM / Resolution: 2.64 Å | |||||||||
Authors | Grieben, M. / Pike, A.C.W. / Saward, B.G. / Wang, D. / Mukhopadhyay, S.M.M. / Moreira, T. / Chalk, R. / MacLean, E.M. / Marsden, B.D. / Burgess-Brown, N.A. ...Grieben, M. / Pike, A.C.W. / Saward, B.G. / Wang, D. / Mukhopadhyay, S.M.M. / Moreira, T. / Chalk, R. / MacLean, E.M. / Marsden, B.D. / Burgess-Brown, N.A. / Bountra, C. / Schofield, C.J. / Carpenter, E.P. / Structural Genomics Consortium (SGC) | |||||||||
Funding support | United Kingdom, 2items
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Citation | Journal: TO BE PUBLISHED Title: Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60 Authors: Grieben, M. / Saward, B.G. / Pike, A.C.W. / Schofield, C.J. / Carpenter, E.P. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7or1.cif.gz | 481 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7or1.ent.gz | 370.3 KB | Display | PDB format |
PDBx/mmJSON format | 7or1.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/or/7or1 ftp://data.pdbj.org/pub/pdb/validation_reports/or/7or1 | HTTPS FTP |
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-Related structure data
Related structure data | 13037MC 7or0C M: map data used to model this data C: citing same article (ref.) |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-Links
-Assembly
Deposited unit |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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