- PDB-4g82: Crystal Structure of p73 DNA-Binding Domain Tetramer bound to a F... -
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基本情報
登録情報
データベース: PDB / ID: 4g82
タイトル
Crystal Structure of p73 DNA-Binding Domain Tetramer bound to a Full Response-Element
要素
DNA (5'-D(P*GP*AP*AP*CP*AP*TP*GP*TP*TP*C)-3')
Tumor protein p73P73
キーワード
DNA binding protein/DNA / beta-immunoglobulin like fold / TUMOR SUPPRESSOR (がん抑制遺伝子) / dna (デオキシリボ核酸) / DNA binding protein-DNA complex
機能・相同性
機能・相同性情報
positive regulation of lung ciliated cell differentiation / negative regulation of cardiac muscle cell proliferation / TP53 Regulates Transcription of Death Receptors and Ligands / Activation of PUMA and translocation to mitochondria / Regulation of TP53 Activity through Association with Co-factors / positive regulation of oligodendrocyte differentiation / TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain / TP53 Regulates Transcription of Caspase Activators and Caspases / TP53 Regulates Transcription of Genes Involved in Cytochrome C Release / negative regulation of neuron differentiation ...positive regulation of lung ciliated cell differentiation / negative regulation of cardiac muscle cell proliferation / TP53 Regulates Transcription of Death Receptors and Ligands / Activation of PUMA and translocation to mitochondria / Regulation of TP53 Activity through Association with Co-factors / positive regulation of oligodendrocyte differentiation / TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain / TP53 Regulates Transcription of Caspase Activators and Caspases / TP53 Regulates Transcription of Genes Involved in Cytochrome C Release / negative regulation of neuron differentiation / DNAミスマッチ修復 / intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator / MDM2/MDM4 family protein binding / response to organonitrogen compound / regulation of mitotic cell cycle / transcription corepressor binding / kidney development / protein tetramerization / intrinsic apoptotic signaling pathway in response to DNA damage / p53 binding / 細胞結合 / RUNX1 regulates transcription of genes involved in differentiation of HSCs / 遺伝子発現の調節 / DNA-binding transcription activator activity, RNA polymerase II-specific / DNA-binding transcription factor binding / RNA polymerase II-specific DNA-binding transcription factor binding / positive regulation of MAPK cascade / transcription cis-regulatory region binding / regulation of cell cycle / DNA-binding transcription factor activity, RNA polymerase II-specific / response to xenobiotic stimulus / 細胞周期 / positive regulation of apoptotic process / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / negative regulation of cell population proliferation / intracellular membrane-bounded organelle / DNA damage response / クロマチン / regulation of transcription by RNA polymerase II / protein kinase binding / positive regulation of DNA-templated transcription / ゴルジ体 / positive regulation of transcription by RNA polymerase II / 核質 / identical protein binding / metal ion binding / 細胞核 / 細胞質基質 類似検索 - 分子機能