登録情報 | データベース: PDB / ID: 9jur |
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タイトル | Crystal Structure of NHL domain of human E3 ubiquitin-protein ligase TRIM71 |
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要素 | E3 ubiquitin-protein ligase TRIM71 |
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キーワード | RNA BINDING PROTEIN / NHL domain / E3 ubiquitin-protein ligase / RNA binding |
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機能・相同性 | 機能・相同性情報
positive regulation of miRNA-mediated gene silencing / 3'-UTR-mediated mRNA destabilization / regulation of neural precursor cell proliferation / miRNA processing / miRNA-mediated gene silencing by inhibition of translation / miRNA binding / neural tube development / post-transcriptional regulation of gene expression / fibroblast growth factor receptor signaling pathway / protein autoubiquitination ...positive regulation of miRNA-mediated gene silencing / 3'-UTR-mediated mRNA destabilization / regulation of neural precursor cell proliferation / miRNA processing / miRNA-mediated gene silencing by inhibition of translation / miRNA binding / neural tube development / post-transcriptional regulation of gene expression / fibroblast growth factor receptor signaling pathway / protein autoubiquitination / translation repressor activity / stem cell proliferation / neural tube closure / P-body / G1/S transition of mitotic cell cycle / RING-type E3 ubiquitin transferase / protein polyubiquitination / ubiquitin-protein transferase activity / ubiquitin protein ligase activity / Antigen processing: Ubiquitination & Proteasome degradation / proteasome-mediated ubiquitin-dependent protein catabolic process / negative regulation of translation / zinc ion binding類似検索 - 分子機能 : / NHL repeat profile. / NHL repeat / NHL repeat / Filamin/ABP280 repeat / Filamin-type immunoglobulin domains / Filamin/ABP280 repeat / Filamin/ABP280 repeat profile. / Filamin/ABP280 repeat-like / B-box zinc finger ...: / NHL repeat profile. / NHL repeat / NHL repeat / Filamin/ABP280 repeat / Filamin-type immunoglobulin domains / Filamin/ABP280 repeat / Filamin/ABP280 repeat profile. / Filamin/ABP280 repeat-like / B-box zinc finger / B-Box-type zinc finger / B-box-type zinc finger / Zinc finger B-box type profile. / Zinc finger, C3HC4 RING-type / Zinc finger, C3HC4 type (RING finger) / Six-bladed beta-propeller, TolB-like / Zinc finger, RING-type, conserved site / Zinc finger RING-type signature. / Ring finger / Zinc finger RING-type profile. / Zinc finger, RING-type / Immunoglobulin E-set / Zinc finger, RING/FYVE/PHD-type / Immunoglobulin-like fold類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.85 Å |
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データ登録者 | Lv, M.Q. / Kazy, E.H. |
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資金援助 | 中国, 1件 組織 | 認可番号 | 国 |
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National Natural Science Foundation of China (NSFC) | 32293213;32100958 | 中国 |
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引用 | ジャーナル: Int.J.Biol.Macromol. / 年: 2025 タイトル: Human tripartite motif-containing protein 71 NCL-1/HT2A/LIN-41 domain crystal structure and its potential natural inhibitors. 著者: Lin, L. / Hasan, M.K.E. / Gu, X. / Khan, S.U. / Hossain, A. / Faruqe, M.O. / Shahriar, S. / Joy, M.N.H. / Sourov, M.M.H. / Khan, M.I. / Zhang, L. / Lv, M. / Shi, Y. |
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履歴 | 登録 | 2024年10月8日 | 登録サイト: PDBJ / 処理サイト: PDBC |
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改定 1.0 | 2025年4月30日 | Provider: repository / タイプ: Initial release |
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