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- PDB-9djw: X-ray crystal structure of TNFa-VNAR D1 complex -

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Basic information

Entry
Database: PDB / ID: 9djw
TitleX-ray crystal structure of TNFa-VNAR D1 complex
Components
  • Antigen receptor
  • Tumor necrosis factor
KeywordsTOXIN / DNA binding / deaminase
Function / homology
Function and homology information


negative regulation of L-glutamate import across plasma membrane / negative regulation of bile acid secretion / response to Gram-negative bacterium / positive regulation of neutrophil activation / positive regulation of fractalkine production / negative regulation of branching involved in lung morphogenesis / positive regulation of interleukin-33 production / positive regulation of blood microparticle formation / positive regulation of chronic inflammatory response to antigenic stimulus / response to 3,3',5-triiodo-L-thyronine ...negative regulation of L-glutamate import across plasma membrane / negative regulation of bile acid secretion / response to Gram-negative bacterium / positive regulation of neutrophil activation / positive regulation of fractalkine production / negative regulation of branching involved in lung morphogenesis / positive regulation of interleukin-33 production / positive regulation of blood microparticle formation / positive regulation of chronic inflammatory response to antigenic stimulus / response to 3,3',5-triiodo-L-thyronine / positive regulation of protein transport / positive regulation of leukocyte adhesion to arterial endothelial cell / positive regulation of vitamin D biosynthetic process / positive regulation of translational initiation by iron / regulation of membrane lipid metabolic process / regulation of endothelial cell apoptotic process / response to macrophage colony-stimulating factor / chronic inflammatory response to antigenic stimulus / regulation of branching involved in salivary gland morphogenesis / negative regulation of protein-containing complex disassembly / positive regulation of humoral immune response mediated by circulating immunoglobulin / positive regulation of hair follicle development / negative regulation of myelination / response to gold nanoparticle / negative regulation of vascular wound healing / negative regulation of cytokine production involved in immune response / negative regulation of amyloid-beta clearance / positive regulation of interleukin-18 production / inflammatory response to wounding / death receptor agonist activity / positive regulation of action potential / TNF signaling / epithelial cell proliferation involved in salivary gland morphogenesis / toll-like receptor 3 signaling pathway / negative regulation of D-glucose import / embryonic digestive tract development / leukocyte migration involved in inflammatory response / vascular endothelial growth factor production / positive regulation of fever generation / response to fructose / positive regulation of neuroinflammatory response / positive regulation of synoviocyte proliferation / necroptotic signaling pathway / positive regulation of calcineurin-NFAT signaling cascade / positive regulation of mononuclear cell migration / leukocyte tethering or rolling / positive regulation of hepatocyte proliferation / negative regulation of myoblast differentiation / positive regulation of protein-containing complex disassembly / regulation of establishment of endothelial barrier / endothelial cell apoptotic process / negative regulation of oxidative phosphorylation / cellular response to toxic substance / positive regulation of protein localization to cell surface / macrophage activation involved in immune response / negative regulation of systemic arterial blood pressure / positive regulation of osteoclast differentiation / tumor necrosis factor receptor binding / positive regulation of heterotypic cell-cell adhesion / positive regulation of macrophage derived foam cell differentiation / positive regulation of cytokine production involved in inflammatory response / regulation of immunoglobulin production / TNFR1-mediated ceramide production / positive regulation of programmed cell death / negative regulation of mitotic cell cycle / positive regulation of podosome assembly / positive regulation of membrane protein ectodomain proteolysis / positive regulation of chemokine (C-X-C motif) ligand 2 production / regulation of fat cell differentiation / response to L-glutamate / regulation of canonical NF-kappaB signal transduction / positive regulation of extrinsic apoptotic signaling pathway / positive regulation of leukocyte adhesion to vascular endothelial cell / TNFR1-induced proapoptotic signaling / negative regulation of bicellular tight junction assembly / regulation of metabolic process / regulation of reactive oxygen species metabolic process / positive regulation of DNA biosynthetic process / negative regulation of heart rate / T cell receptor complex / negative regulation of viral genome replication / positive regulation of amyloid-beta formation / response to isolation stress / negative regulation of fat cell differentiation / regulation of synapse organization / negative regulation of endothelial cell proliferation / positive regulation of JUN kinase activity / positive regulation of MAP kinase activity / Interleukin-10 signaling / negative regulation of interleukin-6 production / humoral immune response / negative regulation of apoptotic signaling pathway / negative regulation of blood vessel endothelial cell migration / positive regulation of glial cell proliferation / negative regulation of lipid storage / extrinsic apoptotic signaling pathway via death domain receptors / cell surface receptor signaling pathway via JAK-STAT / negative regulation of extrinsic apoptotic signaling pathway in absence of ligand / skeletal muscle contraction / negative regulation of osteoblast differentiation
Similarity search - Function
Tumour necrosis factor alpha / Tumour necrosis factor / : / Tumour necrosis factor, conserved site / Tumor necrosis factor (TNF) homology domain (THD) signature. / Tumour necrosis factor family. / TNF(Tumour Necrosis Factor) family / Tumour necrosis factor domain / Tumor necrosis factor (TNF) homology domain (THD) profile. / Tumour necrosis factor-like domain superfamily ...Tumour necrosis factor alpha / Tumour necrosis factor / : / Tumour necrosis factor, conserved site / Tumor necrosis factor (TNF) homology domain (THD) signature. / Tumour necrosis factor family. / TNF(Tumour Necrosis Factor) family / Tumour necrosis factor domain / Tumor necrosis factor (TNF) homology domain (THD) profile. / Tumour necrosis factor-like domain superfamily / Immunoglobulin V-Type / Immunoglobulin V-set domain / Immunoglobulin V-set domain / Immunoglobulin subtype / Immunoglobulin / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulin-like fold
Similarity search - Domain/homology
Tumor necrosis factor / Antigen receptor
Similarity search - Component
Biological speciesSqualus acanthias (spiny dogfish)
Homo sapiens (human)
MethodX-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.43 Å
AuthorsUbah, O.C. / Shi, K. / Aihara, H. / Barelle, C.J. / LeBeau, A.M.
Funding support United States, 1items
OrganizationGrant numberCountry
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)GM118047 United States
CitationJournal: To Be Published
Title: The structural basis for the selective antagonism of soluble TNF-alpha by multivalent, bi-paratopic variable new antigen receptor (VNAR).
Authors: Ubah, O.C. / Shi, K. / Aihara, H. / LeBeau, A.M. / Barelle, C.J.
History
DepositionSep 6, 2024Deposition site: RCSB / Processing site: RCSB
Revision 1.0Sep 10, 2025Provider: repository / Type: Initial release
Revision 2.0Oct 15, 2025Group: Atomic model / Data collection ...Atomic model / Data collection / Derived calculations / Refinement description / Structure summary
Category: atom_site / atom_site_anisotrop ...atom_site / atom_site_anisotrop / pdbx_contact_author / pdbx_nonpoly_scheme / pdbx_refine_tls / pdbx_refine_tls_group / pdbx_struct_sheet_hbond / pdbx_validate_peptide_omega / pdbx_validate_rmsd_angle / pdbx_validate_torsion / refine / refine_hist / refine_ls_restr / refine_ls_shell / struct_conf / struct_conn / struct_sheet / struct_sheet_order / struct_sheet_range
Item: _atom_site.B_iso_or_equiv / _atom_site.Cartn_x ..._atom_site.B_iso_or_equiv / _atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _atom_site.auth_asym_id / _atom_site.auth_seq_id / _atom_site.occupancy / _atom_site_anisotrop.U[1][1] / _atom_site_anisotrop.U[1][2] / _atom_site_anisotrop.U[1][3] / _atom_site_anisotrop.U[2][2] / _atom_site_anisotrop.U[2][3] / _atom_site_anisotrop.U[3][3] / _pdbx_nonpoly_scheme.auth_seq_num / _pdbx_nonpoly_scheme.pdb_seq_num / _pdbx_nonpoly_scheme.pdb_strand_id / _refine.ls_R_factor_R_free / _refine.ls_R_factor_R_work / _refine.ls_R_factor_obs / _refine.ls_d_res_high / _refine.ls_number_reflns_R_free / _refine.ls_number_reflns_obs / _refine.ls_percent_reflns_obs / _refine.overall_SU_ML / _refine.pdbx_ls_sigma_F / _refine.pdbx_overall_phase_error / _refine_hist.d_res_high / _refine_ls_shell.R_factor_R_free / _refine_ls_shell.R_factor_R_work / _refine_ls_shell.d_res_high / _refine_ls_shell.d_res_low / _refine_ls_shell.number_reflns_R_free / _refine_ls_shell.number_reflns_R_work / _refine_ls_shell.percent_reflns_obs / _struct_conn.pdbx_dist_value
Description: Real space R-factor / Details: Resolution cutoff: from 3.31 to 3.43 / Provider: author / Type: Coordinate replacement

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

Downloads & links

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Assembly

Deposited unit
0: Antigen receptor
1: Antigen receptor
2: Tumor necrosis factor
3: Tumor necrosis factor
4: Tumor necrosis factor
5: Antigen receptor
6: Antigen receptor
7: Antigen receptor
A: Tumor necrosis factor
B: Tumor necrosis factor
C: Tumor necrosis factor
D: Antigen receptor
E: Antigen receptor
F: Antigen receptor
G: Tumor necrosis factor
H: Tumor necrosis factor
I: Tumor necrosis factor
J: Antigen receptor
K: Antigen receptor
L: Antigen receptor
M: Tumor necrosis factor
N: Tumor necrosis factor
O: Tumor necrosis factor
P: Antigen receptor
Q: Antigen receptor
R: Antigen receptor
S: Tumor necrosis factor
T: Tumor necrosis factor
U: Tumor necrosis factor
V: Antigen receptor
W: Antigen receptor
X: Antigen receptor
Y: Tumor necrosis factor
Z: Tumor necrosis factor
a: Tumor necrosis factor
b: Antigen receptor
c: Antigen receptor
d: Antigen receptor
e: Tumor necrosis factor
f: Tumor necrosis factor
g: Tumor necrosis factor
h: Antigen receptor
i: Antigen receptor
j: Antigen receptor
k: Tumor necrosis factor
l: Tumor necrosis factor
m: Tumor necrosis factor
n: Antigen receptor
o: Antigen receptor
p: Antigen receptor
q: Tumor necrosis factor
r: Tumor necrosis factor
s: Tumor necrosis factor
t: Antigen receptor
u: Antigen receptor
v: Antigen receptor
w: Tumor necrosis factor
x: Tumor necrosis factor
y: Tumor necrosis factor
z: Antigen receptor
hetero molecules


Theoretical massNumber of molelcules
Total (without water)942,44481
Polymers940,55460
Non-polymers1,88921
Water1629
1


  • Idetical with deposited unit
  • defined by author&software
  • Evidence: gel filtration
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Unit cell
Length a, b, c (Å)112.320, 218.127, 236.485
Angle α, β, γ (deg.)90.00, 96.28, 90.00
Int Tables number4
Space group name H-MP1211

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Components

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Protein , 2 types, 60 molecules 01567DEFJKLPQRVWXbcdhijnoptuvz...

#1: Protein ...
Antigen receptor


Mass: 14080.289 Da / Num. of mol.: 30
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Squalus acanthias (spiny dogfish) / Gene: NAR / Production host: Escherichia coli (E. coli) / References: UniProt: Q8JGJ1
#2: Protein ...
Tumor necrosis factor / Cachectin / TNF-alpha / Tumor necrosis factor ligand superfamily member 2 / TNF-a


Mass: 17271.527 Da / Num. of mol.: 30
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Homo sapiens (human) / Gene: TNF, TNFA, TNFSF2 / Production host: Escherichia coli (E. coli) / References: UniProt: P01375

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Non-polymers , 4 types, 30 molecules

#3: Chemical
ChemComp-GOL / GLYCEROL / GLYCERIN / PROPANE-1,2,3-TRIOL


Mass: 92.094 Da / Num. of mol.: 17 / Source method: obtained synthetically / Formula: C3H8O3
#4: Chemical ChemComp-SO4 / SULFATE ION


Mass: 96.063 Da / Num. of mol.: 3 / Source method: isolated from a natural source / Formula: SO4
#5: Chemical ChemComp-CL / CHLORIDE ION


Mass: 35.453 Da / Num. of mol.: 1 / Source method: obtained synthetically / Formula: Cl
#6: Water ChemComp-HOH / water


Mass: 18.015 Da / Num. of mol.: 9 / Source method: isolated from a natural source / Formula: H2O

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Details

Has ligand of interestN
Has protein modificationY

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Experimental details

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Experiment

ExperimentMethod: X-RAY DIFFRACTION / Number of used crystals: 1

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Sample preparation

CrystalDensity Matthews: 3.26 Å3/Da / Density % sol: 62.23 %
Crystal growTemperature: 291 K / Method: vapor diffusion, hanging drop
Details: 19 % PEG 8000, 0.2 M ammonium sulphate and 0.1 M MES pH 6.0

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Data collection

DiffractionMean temperature: 100 K / Serial crystal experiment: N
Diffraction sourceSource: SYNCHROTRON / Site: PETRA III, EMBL c/o DESY / Beamline: P14 (MX2) / Wavelength: 0.984 Å
DetectorType: DECTRIS EIGER2 S 16M / Detector: PIXEL / Date: Oct 22, 2018
RadiationProtocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelengthWavelength: 0.984 Å / Relative weight: 1
ReflectionResolution: 3.31→109.302 Å / Num. obs: 155984 / % possible obs: 92.8 % / Redundancy: 3.5 % / Rmerge(I) obs: 0.579 / Net I/σ(I): 3.23
Reflection shellResolution: 3.31→3.51 Å / Redundancy: 1.9 % / Rmerge(I) obs: 2.725 / Num. unique obs: 1043

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Processing

Software
NameVersionClassification
PHENIX(1.21.2_5419: ???)refinement
XDSdata reduction
XSCALEdata scaling
PHASERphasing
RefinementMethod to determine structure: MOLECULAR REPLACEMENT / Resolution: 3.43→109.06 Å / SU ML: 0.62 / Cross valid method: FREE R-VALUE / σ(F): 1.34 / Phase error: 29.97 / Stereochemistry target values: ML
RfactorNum. reflection% reflection
Rfree0.2885 7516 5 %
Rwork0.2303 --
obs0.2332 150372 99.44 %
Solvent computationShrinkage radii: 0.9 Å / VDW probe radii: 1.1 Å / Solvent model: FLAT BULK SOLVENT MODEL
Refinement stepCycle: LAST / Resolution: 3.43→109.06 Å
ProteinNucleic acidLigandSolventTotal
Num. atoms60710 0 118 9 60837
Refine LS restraints
Refine-IDTypeDev idealNumber
X-RAY DIFFRACTIONf_bond_d0.00461990
X-RAY DIFFRACTIONf_angle_d0.92284193
X-RAY DIFFRACTIONf_dihedral_angle_d13.88222647
X-RAY DIFFRACTIONf_chiral_restr0.0579463
X-RAY DIFFRACTIONf_plane_restr0.00610962
LS refinement shell
Resolution (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkRefine-ID% reflection obs (%)
3.43-3.470.39962480.35564711X-RAY DIFFRACTION99
3.47-3.510.39252530.32834812X-RAY DIFFRACTION100
3.51-3.550.36772470.32074687X-RAY DIFFRACTION100
3.55-3.60.35482520.32164791X-RAY DIFFRACTION100
3.6-3.640.36112500.31354756X-RAY DIFFRACTION100
3.64-3.690.39482480.34494723X-RAY DIFFRACTION99
3.69-3.750.40282510.33114768X-RAY DIFFRACTION99
3.75-3.80.35572460.29454677X-RAY DIFFRACTION99
3.8-3.860.32662530.29724801X-RAY DIFFRACTION99
3.86-3.930.37422460.31834676X-RAY DIFFRACTION98
3.93-3.990.36922500.29284747X-RAY DIFFRACTION99
3.99-4.070.32022490.26184745X-RAY DIFFRACTION99
4.07-4.140.32042510.24344754X-RAY DIFFRACTION99
4.14-4.230.29282500.23464751X-RAY DIFFRACTION99
4.23-4.320.26282510.2214767X-RAY DIFFRACTION99
4.32-4.420.2642460.22054685X-RAY DIFFRACTION99
4.42-4.530.28222530.21054796X-RAY DIFFRACTION99
4.53-4.660.28492510.19594770X-RAY DIFFRACTION100
4.66-4.790.24192490.18674731X-RAY DIFFRACTION100
4.79-4.950.2542510.19044777X-RAY DIFFRACTION100
4.95-5.120.25682510.18594766X-RAY DIFFRACTION99
5.12-5.330.22712500.19114755X-RAY DIFFRACTION99
5.33-5.570.27212530.20444800X-RAY DIFFRACTION100
5.57-5.860.26392500.20314760X-RAY DIFFRACTION100
5.87-6.230.26922530.20444804X-RAY DIFFRACTION100
6.23-6.710.28322500.21474769X-RAY DIFFRACTION100
6.71-7.390.28432540.19784821X-RAY DIFFRACTION100
7.39-8.460.2592530.1784810X-RAY DIFFRACTION100
8.46-10.650.18162530.14954803X-RAY DIFFRACTION100
10.66-109.060.25842540.21254843X-RAY DIFFRACTION98
Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

IDL112)L122)L132)L222)L232)L332)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T112)T122)T132)T222)T232)T332)Origin x (Å)Origin y (Å)Origin z (Å)
10.16820.09320.10630.375-0.01440.2612-0.22910.13540.30840.2838-0.1874-0.26170.06780.2421-0.29061.2391-0.3038-0.23010.35520.27230.95233.895544.378919.2316
20.41730.1550.37310.09970.391.5830.2537-0.0523-0.10820.2607-0.3399-0.00340.0034-0.8671-0.08841.124-0.111-0.20190.42070.15021.164630.033440.96327.5542
30.151-0.05990.1340.2709-0.07570.271-0.764-0.5368-0.7779-0.15390.40080.25250.22540.5827-0.00380.93-0.038-0.28980.76990.08580.945537.589937.084227.7747
40.00140.0170.03530.08960.1650.2779-0.4302-0.19590.25230.40430.07410.04540.65460.1376-0.02520.5135-0.0358-0.23180.89410.12161.048339.219537.596624.7516
51.73351.4864-0.28861.3861-0.16960.0551-0.66850.127-0.1657-0.35180.5933-0.465-0.23760.19060.17451.0411-0.2736-0.13070.5020.12530.6831.466934.649422.8679
60.3759-0.0631-0.0250.34810.00140.0004-0.3435-0.15050.16370.34770.66940.6688-0.1284-0.3119-0.34860.56120.4093-0.70240.09970.38131.1392-29.395122.4472-2.5059
70.11660.17810.1240.26470.12931.0631-0.13940.5350.7826-0.6817-0.38340.2601-0.6643-0.0053-0.34620.92420.4839-0.15170.8770.58061.4922-25.481735.0145-2.2967
80.0272-0.0493-0.06490.10290.1260.15290.09180.0640.4269-0.24570.0150.028-0.3282-0.31810.15631.11250.3147-0.46910.94310.13831.8185-34.689924.48183.317
90.5182-0.1139-0.16780.7979-0.34960.22430.02-0.13280.8080.093-0.398-0.2542-0.47130.0925-0.0050.52920.0459-0.04580.30330.2440.9067-24.915228.1624-0.6301
101.31470.82110.29510.918-0.04990.58420.0343-0.53440.044-0.3127-0.25980.04580.1636-0.2725-0.00550.38260.1893-0.02340.4985-0.09920.485167.1238-4.446935.5963
11-0.00090.0001-0.0065-0.00220.00020.0078-0.0097-0.2830.01450.2891-0.2120.38090.3804-0.1780.00031.1258-0.1881-0.34471.5722-0.32171.752683.307320.475134.6516
121.1284-0.15190.91740.3764-0.29840.9032-0.51810.02930.75270.1193-0.24290.0097-0.298-0.1333-0.36350.51630.02530.13760.4982-0.2350.723569.8359-1.028437.5115
133.0095-0.54341.56020.13-0.32020.8322-0.9436-0.90680.43230.0720.0715-0.1253-0.0106-0.3944-0.62560.70450.11320.22440.9509-0.12720.426160.2623-6.266655.6149
140.54580.7061-0.3121.1368-0.61920.3643-0.3545-0.27840.6262-0.14110.58480.0342-0.1113-0.16560.15730.73090.10730.1671.4699-0.68051.02460.7382.653959.3016
150.7485-0.84760.1641.0285-0.20050.2632-0.0229-1.29860.90580.46320.032-0.3894-0.3728-0.2476-0.05160.47390.1248-0.14121.6881-0.47050.720269.4745-4.413960.4531
160.0109-0.0150.00120.03420.02520.02360.0692-0.2605-0.05420.06420.12250.00660.20160.350301.17690.0779-0.04541.205-0.68281.924880.92921.124853.2849
171.0021-0.0108-0.01480.01220.00590.08070.0179-0.99411.09450.0327-0.1357-0.0517-0.25320.58520.0250.52730.2291-0.10121.1025-0.42690.721880.1411-1.278963.5687
180.0029-0.00350.00140.007-0.00520.0064-0.04430.0347-0.0466-0.077-0.1956-0.0713-0.335-0.2629-0.00011.546-0.0666-0.10691.1657-0.54382.129283.494422.597847.34
190.00590.0069-0.00660.0226-0.00550.0082-0.13960.209-0.27760.0366-0.21670.17750.0189-0.12940.00012.94030.50110.88821.65460.39892.166376.067228.584645.3563
201.0514-0.03830.260.46330.11190.10040.0556-1.30740.74540.1226-0.04240.5027-0.5684-0.29980.04350.602-0.0262-0.01241.0384-0.32790.623776.11221.083952.342
210.0243-0.13690.05652.02860.85531.02130.1004-0.57510.4076-0.4776-0.0038-0.1754-0.55350.3025-0.65590.50270.0971-0.05181.6265-0.67380.527270.22172.258758.2536
220.0303-0.0061-0.0048-0.0033-0.00370.01320.24990.04150.21060.7801-0.13310.126-0.0781-0.0510.00042.0353-0.2121-0.27181.2599-0.08360.798177.66-23.896362.1041
231.0134-0.56760.31490.3833-0.16250.097-0.2274-0.56680.3246-0.14150.1973-0.2794-0.595-0.4297-0.06010.6711-0.09350.180.9617-0.06580.461893.5655-8.757854.3968
240.0922-0.08720.12050.0822-0.11150.16230.84930.0279-0.09990.1505-0.2607-0.1006-0.035-0.19710.01990.4997-0.08390.02170.90830.02970.39189.2976-17.85252.1501
250.048-0.0013-0.28480.746-0.47971.8792-0.4720.11970.352-0.3890.53430.67930.71480.1793-0.05970.448-0.0102-0.06540.4184-0.11730.457983.7529-11.820545.8416
260.263-0.21620.03010.1693-0.02630.0042-0.2469-0.24990.2068-0.37920.30840.05220.0191-0.20780.03480.7416-0.7228-0.28851.467-0.22491.80794.916114.478641.154
270.0353-0.0415-0.00020.149-0.17920.24320.0384-0.51460.64940.1843-0.2308-0.1741-0.1090.4657-0.01090.5258-0.00910.02450.4646-0.1140.532486.9066-8.183835.9827
280.19720.0662-0.01360.2560.10420.04440.05390.0609-0.12780.1974-0.36250.09430.2419-0.0295-0.19160.8005-0.4384-0.01031.3909-0.34211.963792.293619.614444.4988
290.11570.08380.12670.1908-0.23081.01020.344-0.53550.5251-0.2736-0.1209-0.46040.3641-0.22160.13020.37390.15590.09750.4864-0.0930.560684.081-9.67942.3476
300.0392-0.0599-0.02270.08180.0270.04350.2582-0.26240.39350.34010.13770.0960.2916-0.1792-0.00020.55470.0584-0.1460.8335-0.21970.627588.6557-2.969750.0715
310.8024-0.58160.22610.6203-0.40620.25920.16150.040.2488-0.0105-0.2334-0.119-0.4655-0.0991-0.00280.4951-0.0126-0.03950.34530.09090.483.175-19.36179.0698
320.3376-0.2079-0.00420.1160.03460.1487-0.06220.17230.51820.17470.42740.0605-0.2455-0.58110.12970.5750.16110.0250.29370.30830.432580.5533-15.75136.6325
330.23490.10030.00480.367-0.32780.31420.02770.13140.75630.41150.0748-0.4248-0.2468-0.46230.20790.62450.06340.00150.50040.18750.543481.4978-15.34313.2575
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1200.6329-0.1083-0.06470.24010.1070.05510.2416-0.63260.1151-0.7943-0.2172-0.44810.01280.0675-0.02640.4088-0.09860.11490.4308-0.05380.8565-14.1261-16.46932.0402
1210.576-0.09050.11480.8915-0.19950.06510.0823-0.1733-0.3507-0.6724-0.1545-0.04020.1240.1496-0.63660.73560.258-0.10550.16550.25710.5187-5.9198-9.556220.2553
1220.2520.1724-0.11920.57050.54381.62770.1834-0.31030.00220.0634-0.23840.4101-0.911-0.2531-0.0310.4512-0.1136-0.00810.41030.13630.6398-8.7219-16.354730.2251
1231.07610.34480.84720.13680.31051.0121-0.0309-0.23840.0739-0.1585-0.3909-0.001-0.1632-0.44290.0670.57340.1960.02060.47240.07720.5172-8.8586-21.128222.5697
1240.07610.04060.00060.01970.00850.04850.0178-0.04980.13930.074-0.01270.0655-0.07080.1322-0.37560.8921-0.29990.2170.1274-0.36950.78237.1791-68.9169-19.9206
1250.0239-0.0211-0.0027-0.0050.0030.0141-0.64070.00910.2548-0.37090.05660.24080.17550.3645-0.00090.6940.13270.07430.9032-0.25930.866318.2533-71.0896-26.26
1260.08380.016-0.11340.28690.1410.2166-0.39730.2860.346-0.1560.1447-0.6159-0.2258-0.1665-0.00030.91870.00270.24020.6851-0.03211.097814.0987-60.6928-24.0096
127-0.0003-0.0168-0.01830.02260.02690.0635-0.1508-0.3296-0.5768-0.52790.03640.3147-0.16920.3325-0.00010.7645-0.17150.18210.5806-0.04670.85188.3472-59.7035-18.6832
1280.04470.0141-0.00560.01360.01390.02740.41430.0643-0.01740.23750.3096-0.02840.25190.2648-0.00071.0116-0.26290.26330.64310.11781.0762-44.8925-60.19559.8162
1290.6528-0.1067-0.4220.02820.07850.3143-0.06140.07290.217-0.6341-0.67840.20.14-1.0572-0.2810.8275-0.45670.10990.6483-0.14141.2026-53.818-67.452910.7454
1300.0583-0.0277-0.03090.02310.0031-0.00210.5923-0.00210.13730.0058-0.17710.160.0707-0.47280.00011.2636-0.3882-0.0080.8884-0.0951.2268-48.0262-67.67470.4079
1310.0576-0.01950.02510.0059-0.0240.0617-0.1442-0.17290.03080.0582-0.25270.19870.75660.6367-0.00031.492-0.42460.0661.3497-0.26691.9514-49.4203-77.31470.8662
1320.05130.0176-0.00670.0079-0.00430.0093-0.1408-0.22690.67130.19220.21930.0771-0.1074-0.44160.00081.0716-0.23140.29040.8891-0.47811.8993-57.2269-62.39233.22
1330.01830.0185-0.01290.0174-0.01240.00780.03240.15220.21090.02090.01670.3220.0829-0.03530.00022.5367-0.47480.22541.0304-0.20121.9681-57.354-81.49226.7107
1340.3119-0.11310.19940.1054-0.08350.1456-0.07850.1570.06670.4408-0.64170.1308-0.0151-0.2936-0.06330.8015-0.18820.02110.5225-0.2071.0127-42.3554-61.53160.6505
1350.07750.14630.04450.36590.21090.21160.1509-0.0114-0.0342-0.13730.19830.05280.03010.02710.2541.5268-0.68540.51910.64950.30032.0549-52.7124-78.773313.7634
1360.0271-0.01490.01150.0361-0.02190.0213-0.53520.14070.05840.1936-0.3376-0.0410.03520.5282-0.00032.0366-0.1716-0.05851.44460.20512.3654-68.0857-94.574415.038
1370.73070.25420.07710.3445-0.01261.12290.01960.3662-0.0983-0.23080.0629-0.1265-0.21490.01220.01340.38150.14630.15550.1532-0.6651-0.401949.79325.1987117.7621
138-0.0119-0.0040.04090.15130.21860.25050.03770.37240.48650.1369-0.3380.26330.1734-0.3835-0.04290.39160.1107-0.05980.8943-0.20450.566754.21713.3492102.4695
1390.0066-0.00950.0010.0063-0.0007-0.0028-0.0041-0.10150.1401-0.1785-0.24970.2539-0.0183-0.3487-0.0883.0312-1.00281.31222.7127-1.64543.318833.863827.860496.9196
1400.26240.0756-0.10340.30280.11450.1332-0.20321.0387-0.0169-0.66820.23090.2685-0.27030.46590.05580.26330.0571-0.00190.7384-0.37110.681351.1827.2252107.3108
1410.53560.01980.18410.5827-0.12810.1006-0.1080.31480.2444-0.50.15370.0981-0.32640.70640.04570.65410.052-0.1140.6897-0.27850.018644.398711.5558112.0002
1420.1757-0.05840.02180.03090.01380.04130.1337-0.06550.0544-0.06830.2068-0.1626-0.28860.22660.29381.23030.5535-0.08880.862-0.50160.792462.1854-14.2035108.0645
1430.51790.2934-0.27790.1671-0.14920.20860.1417-0.39450.1386-0.1908-0.2349-0.2810.24840.6050.09730.46280.18240.17091.0031-0.23130.541455.3821-0.273888.7708
1440.5521-0.73040.32490.9787-0.40820.19670.22620.3513-0.4907-0.0346-0.03530.4057-0.0450.24590.27190.60230.10020.06110.9515-0.45780.404652.0751-7.397894.5313
1450.2416-0.1950.12730.2518-0.09140.07180.49140.1277-0.2206-0.0553-0.02780.327-0.21190.13210.00621.4061-0.45070.3661.5535-0.23870.766336.96115.265682.8952
1460.3321-0.1203-0.0770.18090.03460.0139-0.00190.2676-0.2063-0.0478-0.16880.2552-0.392-0.37240.03210.8550.1222-0.00541.2498-0.63430.512438.652-8.368289.9196
1470.16240.04380.03930.0454-0.05020.0972-0.5492-0.07010.4909-0.2784-0.00290.3428-0.40770.3265-0.00441.79210.18560.25952.07260.06270.960237.386222.737885.2677
1480.3144-0.4384-0.04150.56470.0473-0.0288-0.17930.7921-0.4874-0.16660.12320.4095-0.1348-0.25940.01760.6586-0.03170.00710.7799-0.2920.568943.5203-4.773794.0859
1492.46530.23840.41550.7690.18150.70590.235-0.0362-0.2303-0.32750.0097-0.3455-0.369-0.08111.07770.4480.090.19760.8761-0.28360.538649.39823.119192.0977
1500.26360.0441-0.28860.2209-0.17870.22820.26550.17840.032-0.64-0.1121-0.10451.0186-0.58430.00830.69050.0399-0.15490.5834-0.11310.578331.249-13.6479104.6304
1510.86750.4818-0.972.69620.12741.7717-0.07030.42480.2287-0.16160.59230.76490.6020.30370.09220.4299-0.0066-0.13660.4512-0.15510.530932.9866-5.616110.6989
1520.34930.20190.05410.0547-0.05440.7502-0.1820.14570.7537-0.2638-0.06730.2774-0.0066-0.7782-0.13290.4480.1508-0.06550.6294-0.1570.757129.63686.918111.6054
1531.05120.3574-0.26830.5403-0.2580.1383-0.84490.24550.34290.50.39010.41560.06720.0846-0.00371.60250.5019-0.19521.45740.07693.145225.852119.975591.0752
1540.61570.46860.06850.7462-0.26531.21330.67150.38420.12980.3130.10380.0732-0.5171-0.05680.63890.578-0.03270.08170.6581-0.25280.434234.1477-0.2417110.4129
1550.00980.06570.03840.19680.07110.06550.22030.2834-0.18360.35080.23190.70910.2722-0.33730.00080.5457-0.0656-0.1250.8102-0.03320.723329.885-1.4312101.4632
1560.1779-0.047-0.20880.2186-0.02750.3008-0.20370.5934-0.0459-0.0689-0.0155-0.0514-0.26580.1191-0.23420.4713-0.0369-0.57170.8017-0.2090.510130.098511.6593135.1994
1570.0994-0.2504-0.08411.0268-0.69822.44670.19370.68360.28710.215-0.13720.017-0.5119-0.4663-0.04520.22440.01210.13530.6746-0.16060.776529.060720.7645146.3953
1580.0110.0535-0.04470.3087-0.27340.2410.09930.162-0.33320.10610.25290.20470.39940.02270.08260.31750.2370.15320.7734-0.30720.428634.16250.5086133.7678
1590.0310.07020.05451.0879-0.42382.804-0.17330.68950.3082-0.08610.4249-0.11790.5043-0.18780.07340.3665-0.11760.10350.6778-0.2410.66141.264312.9034140.2472
1600.15690.1245-0.32410.5842-0.70061.1080.09570.00370.0532-0.0262-0.028-0.0474-0.0133-0.2175-0.3150.62820.15440.24930.55050.54780.852943.086229.1022135.9653
1610.00410.003-0.00141.56150.09240.0051-0.2632-0.34330.2014-0.12260.6294-0.4170.07770.0530.0160.3136-0.0666-0.17131.1017-0.15910.898643.339818.5887146.0424
1620.1439-0.028-0.12310.00820.01710.1042-0.00050.0078-0.3136-0.7179-0.0103-0.1125-0.10650.39920.00060.54650.198-0.05440.5987-0.06510.495735.06248.7822147.1644
1630.2829-0.2101-0.43831.1164-0.33091.08840.2104-0.35110.3410.1790.0199-0.46710.02590.33580.03670.9504-0.23190.0560.5957-0.31510.649336.048727.2025149.4724
1640.0773-0.02490.09250.06560.06330.0971-0.12140.3115-0.36150.0314-0.2218-0.34240.15860.2686-0.00320.4822-0.0478-0.00330.6657-0.11170.526340.91547.5868133.2831
1651.112-1.3130.32581.72810.23991.97160.44210.17210.2821-0.4921-0.37850.15420.23380.4873-0.01470.5587-0.1730.10950.4163-0.17370.453730.262129.3331144.6655
1660.0441-0.0069-0.0592-0.00450.01250.06920.4610.11820.003-0.06570.4259-0.02320.02420.1074-0.00041.2891-0.447-0.13421.02560.04180.850521.5383-21.668581.8587
1670.1177-0.0053-0.09890.05810.14470.3686-0.0885-0.10260.0575-0.27480.2886-0.14520.19840.25120.15181.0225-0.2149-0.54561.3736-0.61750.987310.7301-28.921579.1316
1682.39620.6876-0.54420.6769-0.28590.18620.4055-0.353-0.98940.0312-0.3973-0.3589-0.3012-0.4781-0.08981.03550.0637-0.29191.4893-0.4890.938816.735-25.403892.5575
1690.2601-0.14390.20580.9028-1.07071.28010.1975-0.2787-0.0033-0.1780.27870.1730.271-0.04240.19382.1010.5423-0.68161.1849-0.56521.449819.8981-33.708686.5821
1700.0179-0.03650.01450.13120.00570.02140.4962-0.02790.19010.25760.47190.0793-0.08980.02220.00491.0181-0.0775-0.22691.6498-0.29512.10752.3098-28.538484.3117
1710.90240.575-1.79110.9125-1.20883.58350.1294-0.11850.2064-0.353-0.41850.5683-0.54470.7027-1.11571.02670.1679-0.14920.8147-0.62970.925525.5119-22.636495.6017
1720.03240.0352-0.00480.2601-0.18520.12620.00790.1548-0.03610.42420.0717-0.3429-0.4473-0.0794-0.00010.81230.0964-0.44571.202-0.16911.0242-0.696-23.13574.9507
1730.4341-0.43440.17150.7114-0.28070.11670.28990.52370.3235-0.5558-0.3598-0.68640.05590.1041-0.05560.8539-0.18950.22070.9263-0.29920.801476.561612.402591.7665
1740.1587-0.1616-0.10080.3635-0.0950.24460.0577-0.13010.6777-0.65640.5015-0.4747-0.4913-0.2195-0.011.182-0.6870.09951.5905-0.3830.96886.700513.050883.6102
1750.0289-0.0092-0.00630.04780.03480.01560.17760.4290.06370.39-0.6719-0.00161.04040.39260.00160.711-0.21420.0441.2152-0.18010.748175.866-0.053499.3595
1760.2284-0.01740.1330.7456-0.1420.09850.31690.25880.1521-0.2067-0.23960.2387-0.3445-0.55310.07941.0768-0.02590.38191.8943-0.12450.600876.01393.916481.2043
1771.73871.22411.53810.95271.08211.3618-0.63970.5616-0.0091-0.82260.0866-0.17750.3325-0.33130.01451.3044-0.00930.53782.5866-0.27641.270677.95581.991777.7716
1780.0004-0.00070.00350.0008-0.00070.0043-0.0772-0.22220.14660.0969-0.11040.1017-0.07330.0122-0.00051.14130.1213-0.22081.31240.02381.223187.15291.261388.5071
1790.2754-0.18260.65581.3349-1.44562.42710.04350.1110.2750.6738-0.21060.02190.62310.4285-0.4371.09070.16980.24362.1175-0.15010.554985.04714.192892.6299
1800.2142-0.1686-0.0341.4343-0.91940.72470.10890.5486-0.0461-0.20.4514-0.120.12020.20020.63710.8847-0.21680.11521.711-0.44590.632978.59854.941684.0186
1810.0008-0.00640.00370.0171-0.02970.0355-0.55080.37250.2088-0.1734-0.1277-0.1046-0.52650.6182-0.00090.5188-0.0967-0.17481.1846-0.26680.695167.0809-4.598697.0219
1820.021-0.03220.02570.0539-0.03630.02820.09430.19870.5576-0.0482-0.2952-0.27050.10410.02740.00221.21790.09410.32871.5789-0.38251.119974.422610.091885.6022
1830.11390.0521-0.11370.0322-0.04240.1177-0.0860.148-0.0859-0.17360.2320.0704-0.22640.195501.7696-0.4244-0.66271.1350.39261.680785.471818.68472.4916
1840.36090.30110.51250.24370.42490.72550.2433-0.1059-0.39280.18510.8906-0.4626-0.02050.54850.12650.53920.18040.06010.6016-0.08560.764325.5962-40.365618.5393
1850.4412-0.01230.1010.1361-0.28680.57620.00510.36110.22450.31170.17980.3147-0.0529-0.03170.01920.43420.0391-0.01120.22610.13550.408521.9898-29.827640.3151
1860.01490.01740.03340.01180.030.0533-0.575-0.30360.27970.4999-0.3135-0.18230.22260.22650.00041.84140.1913-0.05951.00460.21631.085738.9579-20.026962.1428
1871.0360.78280.43920.48660.34980.21460.1848-0.03610.55570.3605-0.17920.31860.2812-0.22920.02250.396-0.0411-0.11120.47530.17710.48122.2874-33.842843.4337
1881.22590.41970.36832.06851.65521.3365-0.143-0.7573-0.33970.4868-0.2620.3506-0.0346-0.4862-0.65980.60720.07130.0490.33260.13850.079429.0023-27.780841.3472
1890.60030.45950.56432.1410.36372.6228-0.5588-0.0544-0.62560.0033-0.60520.10510.5199-0.6058-3.33960.3989-0.20850.66890.6016-0.15980.75335.2497-50.087234.1858
1901.011-0.17560.48120.3040.16260.43550.0244-0.1888-0.01690.1391-0.03040.13850.3867-0.1729-00.4792-0.04230.06680.3090.05930.390120.7197-51.082751.033
1910.01670.0109-0.00140.0186-0.01740.0225-0.0415-0.26050.44960.4216-0.2843-0.191-0.42870.23110.00050.62480.1011-0.03230.7110.21360.733638.2299-37.278968.4327
1920.7466-0.2310.09080.54260.1171.14120.58150.2773-0.0877-0.2712-0.4828-0.10720.45210.41190.75720.8666-0.1265-0.14540.46250.41280.166735.3411-55.001251.6009
1930.17660.1326-0.07640.1695-0.230.4830.4012-0.04450.2302-0.06750.564-0.1382-0.4487-0.1920.66660.3330.02720.23231.59580.13661.119135.7649-29.475569.5866
1940.50820.173-0.24170.15980.07410.3601-0.0202-0.4294-0.6040.3276-0.1404-0.32740.06260.3909-0.00740.48210.03840.02540.44370.1590.50630.1938-49.425750.0968
1950.24140.0646-0.80390.0429-0.31823.7605-0.34030.3241-0.06230.1661-0.3769-0.28140.5395-0.3185-0.84290.2811-0.0485-0.22220.24520.08570.496924.0437-44.336854.9209
1960.3702-0.2203-0.06540.37710.14140.1611-0.1398-0.0163-0.5354-0.2152-0.0565-0.4216-0.12430.2145-0.04140.4815-0.0344-0.03640.40550.23440.440344.181-50.052134.4845
1970.68910.34370.33280.3902-0.0680.30810.38590.08580.11550.0109-0.20020.41990.14280.0177-0.02240.2611-0.0734-0.02240.30780.05440.301142.5259-37.150946.8571
1980.23260.10840.43740.13160.14510.8112-0.50350.34160.6238-0.1944-0.32260.07450.1699-0.0615-0.44770.4497-0.0428-0.0180.32240.09460.403241.8099-32.617534.6752
1990.36230.03480.03810.0050.0071-0.00170.4043-0.2507-0.28370.3330.01540.007-0.7462-0.230.01341.1393-0.1018-0.01120.8281-0.14510.359347.7754-29.470364.5459
2001.5564-0.10481.11550.2249-0.56681.5186-0.0746-0.51560.0217-0.14630.24-0.5456-0.5877-0.5864-0.1090.4511-0.0550.110.23080.12030.458339.3675-38.604837.1754
2010.1647-0.12960.05850.23090.06910.0984-0.05630.59460.43270.1967-0.49280.02070.16370.6247-0.00140.4246-0.0310.05190.39540.14250.368243.6494-43.587144.8066
2024.3857-1.03181.08380.2548-0.10212.5726-0.18970.32021.0695-0.2373-0.1752-0.3256-0.8828-0.1571-1.41650.31610.3697-0.12660.33290.17160.316743.3607-18.116521.1528
2030.86470.32170.27120.16590.12340.99940.07120.03460.32920.0687-0.1227-0.01250.0892-0.4015-0.0010.3914-0.0030.02240.33930.110.484237.3688-10.690914.6267
2040.51820.43040.35950.87560.04680.54830.01550.41460.57790.51720.2580.8405-0.1395-0.23110.02260.3648-0.03830.11310.52830.05690.600935.7222-12.248619.6755
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2980.09970.07020.05460.290.08870.04230.0110.50780.0985-0.354-0.30350.2436-0.06190.0382-0.1840.93170.5216-0.21161.0810.08971.234-24.3824-96.631881.0765
2991.3427-0.948-1.81050.6791.26332.45910.160.11-0.10180.3808-0.50260.3357-0.9904-0.5959-0.16330.9052-0.0884-0.09950.18580.12890.4768-17.8198-110.713892.7823
3000.08960.1372-0.30671.1731-0.27531.03350.21850.3075-0.0116-0.28970.11360.3852-0.0372-0.31780.57991.01290.2125-0.26420.75740.24390.6668-16.8338-108.840676.505
3010.4746-0.1425-0.34010.17140.26080.56090.3190.42240.1538-0.0582-0.2847-0.111-0.27770.36430.08330.51190.1910.08690.66950.47660.2504-20.9532-99.620696.9126
3020.02690.0105-0.00120.17730.3430.6916-0.38710.02680.36580.0725-0.72930.2792-0.2583-0.2575-0.04861.0220.0572-0.17740.72360.02990.4574-24.3459-95.4475103.7022
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3040.0287-0.00090.0038-0.00050.00340.034-0.0225-0.30580.09750.0156-0.2034-0.07650.09660.0355-0.00041.84340.3567-0.0621.9501-0.09430.8511-8.2484-112.445459.9154
3050.1043-0.0874-0.13440.03730.07940.1769-0.246-0.49530.39260.07410.02570.8546-0.6042-0.3120.00050.80270.24020.02271.4681-0.39071.7111-62.5393-57.204111.9226
3060.0188-0.01160.02790.0349-0.0410.0357-0.2399-0.09450.1558-0.4185-0.1913-0.0692-0.20590.1174-01.1016-0.1105-0.13281.1704-0.23381.6897-57.2228-48.8151119.1506
3070.01370.0286-0.03810.0298-0.02730.1268-0.1137-0.7520.1363-0.2313-0.40420.39770.3711-0.08920.00021.8098-0.12280.14971.4226-0.2172.1234-63.9755-54.5969121.2075
3080.0708-0.0010.04950.0212-0.04620.1111-0.0210.2378-0.0163-0.28230.1821-0.0920.0841-0.59070.00020.9566-0.07520.22331.2268-0.50232.112-67.6007-47.4281116.4638
3090.1461-0.0734-0.20630.0630.08690.25030.0336-0.1570.40640.1534-0.0163-0.22950.11450.2041-0.00050.8150.03610.27020.9432-0.26531.3103-54.4592-58.8551117.5066
3100.03170.00530.02770.0302-0.00810.02790.44280.02290.01160.3110.26760.10080.43260.33670.00031.74630.28660.14721.5862-0.22353.1455-76.8091-28.1506109.0243
3110.0531-0.0097-0.0408-0.00120.0039-0.0153-0.3144-0.08850.48350.2717-0.0756-0.3431-0.0879-0.60050.00011.0418-0.3558-0.39211.0953-0.12191.4230.8831-60.0979142.2477
3120.00960.0152-0.01190.0172-0.02160.02930.3013-0.05610.0384-0.52950.2923-0.135-0.3527-0.17910.00331.4934-0.22860.17221.50510.06331.729311.7333-65.549132.7169
3130.03290.00210.02280.08080.08470.09740.1567-0.09530.2599-0.42150.2664-0.31020.0709-0.25660.00061.23870.0843-0.24871.8619-0.00511.04867.6008-62.3854147.337
3140.01820.0215-0.0020.0328-0.04310.03850.0288-0.215-0.02340.0882-0.06310.05380.02390.3193-0.00061.2309-0.0894-0.48751.2941-0.05681.4145-1.3758-66.787138.6137
3150.03610.0385-0.00360.02880.0021-0.0011-0.4128-0.22330.02930.10840.4509-0.12850.2696-0.4766-0.00031.4088-0.1979-0.52691.3838-0.28921.7777-2.9722-65.2736136.7575
316-0.0079-0.0054-0.02790.0006-0.00910.44790.3879-0.29590.3707-0.0004-0.5805-0.1451-0.3489-0.2441-0.01390.40780.03270.0290.9727-0.07320.7317-20.627-5.3427149.6674
3170.3471-0.0739-0.20590.14410.20990.25810.350.2895-0.3982-0.2695-0.082-0.00020.25050.504-0.0080.61860.1527-0.12690.6905-0.34780.6949-15.284-14.7891126.338
3180.0073-0.01790.0020.0142-0.0009-0.0018-0.04250.0309-0.3970.12670.08220.07060.1173-0.07210.00021.63690.4026-0.83691.1012-0.17171.8612-32.353-22.7949103.8798
3192.7584-0.79451.06820.5456-0.55630.77420.10251.0010.0823-0.12570.05210.156-0.67720.1122-0.12360.69730.3065-0.25721.0106-0.63550.9518-15.4461-19.7557126.7128
3201.53380.11760.25911.62210.09840.74480.49570.4599-0.39680.2196-0.4352-0.38380.1454-0.3104-0.61080.79630.10940.03770.4497-0.63341.0375-22.279-13.8832124.2246
3210.02660.0012-0.01190.0208-0.01270.02160.1397-0.09190.1558-0.1910.59840.0131-0.26340.49150.00091.0145-0.2291-0.39981.10540.05420.9945-4.376-26.2332146.6197
3220.04550.0124-0.03170.12940.15620.17640.07560.05260.1951-0.2167-0.25990.13970.0742-0.0477-0.02410.56340.3802-0.12220.5355-0.82641.997-9.3871-37.9552129.0998
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3240.4103-0.3163-0.08720.19920.06650.01690.36080.2182-0.4976-0.1379-0.23030.3596-0.02950.1002-0.17620.6259-0.0391-0.2160.7218-0.62411.441-20.6198-32.7091130.5882
3250.15710.1760.18680.21280.16050.3068-0.07840.0187-0.0164-0.0180.143-0.41450.17270.24660.02571.8777-0.4482-0.39811.1804-0.8981.4859-29.5001-39.3213109.5741
3260.011-0.0030.04331.46620.73490.7088-0.2506-0.076-0.0812-0.5201-0.44610.40920.0326-0.3639-0.88370.5810.07170.40390.566-0.3991.8414-28.3137-41.34134.7629
3270.09610.0815-0.05190.069-0.04510.0286-0.06120.3191-0.0692-0.3674-0.11960.1795-0.2312-0.19670.02981.47720.1338-0.0991.9494-0.93361.5576-28.4843-34.223103.4449
3280.8124-0.3283-0.24130.4143-0.13410.3202-0.1830.101-0.849-0.1227-0.10890.311-0.0347-0.03520.4310.68910.0837-0.10190.861-0.73941.3831-24.579-31.7113128.6488
3290.4287-0.3626-0.28360.8817-0.0130.4458-0.40890.077-0.00120.02460.3736-0.12230.166-0.09290.00380.9988-0.13310.0310.20540.22121.3327-21.2445-42.866140.9393
3300.0545-0.0566-0.09540.09080.11430.1447-0.34660.207-0.4086-0.143-0.1129-0.01460.1216-0.2296-0.89650.8862-0.143-0.27110.703-0.95781.6905-17.3586-35.5051125.039
3310.14010.273-0.45150.8847-1.31912.00680.16920.3008-0.4220.6434-0.76180.0575-0.15240.0458-0.34320.6893-0.03540.25360.4166-0.15331.4743-33.4158-29.6547145.1025
332-0.00040.0086-0.01090.0577-0.13680.2387-0.3771-0.08780.15970.1305-0.6083-0.0455-0.292-0.2476-0.00620.6125-0.0534-0.02470.602-0.23471.5146-40.4933-30.4136141.0732
3330.080.06730.06840.2723-0.08760.1885-0.3487-0.0941-0.04680.0431-0.11650.4287-0.1076-0.2946-0.42650.15090.1469-0.11070.7458-0.07041.2849-36.6578-18.6728147.4782
334-0.0268-0.03410.06140.40280.35890.6797-0.12950.06240.1067-0.0706-0.15620.48720.11670.1254-0.31550.32180.05160.00280.4707-0.39071.1882-35.8047-24.7395126.4478
3350.145-0.07230.35360.4281-0.24340.89440.03760.5577-0.44290.0547-0.11230.05430.5324-0.62480.41880.5487-0.0355-0.15320.5879-0.28760.9418-35.1795-13.1888132.3653
3360.0403-0.03140.03820.0195-0.03290.0241-0.3699-0.27060.350.0285-0.03390.2099-0.1259-0.3555-0.00021.5453-0.0786-0.27591.1815-0.20492.2123-41.1594-31.4975108.1528
3370.41540.5913-0.13870.7756-0.24720.48420.06540.1766-0.8757-0.128-0.0980.1632-0.3106-0.1329-0.21250.52230.1690.08370.5181-0.21881.0607-32.7999-19.4997134.5698
3380.4895-0.10070.05070.0875-0.10640.24840.18720.1932-0.5432-0.13050.26140.18880.0636-0.17670.11350.29810.10960.20610.5614-0.45541.5046-37.0682-28.2046132.1438
3391.3296-0.3704-0.24262.75620.95690.4129-0.09130.7554-0.19310.3648-0.0812-0.15090.0348-0.1550.1380.2219-0.03360.07680.4969-0.18130.372-33.48213.4862132.8003
3401.03110.15990.49681.8134-0.79860.6906-0.1060.3255-0.1230.4688-0.3935-0.49730.44310.4649-1.1160.16460.38450.55280.3183-0.8879-0.4145-28.832718.3292133.6489
3410.315-0.51790.323.5325-1.65951.51720.29870.8052-0.04320.4802-0.4524-0.269-0.2992-0.2832-0.26890.37820.08840.00840.8936-0.23820.6196-29.106716.3266128.6527
3420.30530.22440.260.20160.06490.1426-0.15650.3637-0.0959-0.1829-0.3161-0.1448-0.0615-0.4484-0.16560.51690.2016-0.14130.7618-0.06030.3801-30.131610.9975130.1476
343-0.0014-0.00210.0020.1004-0.0107-0.0060.02450.0098-0.08650.41990.2498-0.10530.4907-0.131-0.07531.6959-0.49690.77080.8489-0.34142.3915-52.5516-56.8475145.1434
3440.0030.01350.00970.07510.05140.0254-0.2023-0.12340.0911-0.1149-0.0725-0.4036-0.3865-0.396801.8667-0.08650.21931.6063-0.19783.2939-42.1011-46.6936151.1314
3450.0122-0.0023-0.00210.0091-0.00150.0219-0.08620.01460.0652-0.3397-0.2613-0.0166-0.09390.12940.00022.3342-0.42080.3332.3795-0.49722.1231-59.5079-42.2458140.8988
3460.01580.01940.00290.05170.05640.05030.14450.11140.1558-0.0451-0.1813-0.11610.4738-0.11690.00011.4523-0.03260.54531.6320.2761.9689-52.4949-51.8485155.3549
3470.0130.0941-0.1080.2458-0.44670.7094-0.11950.0418-0.36690.2329-0.28810.0327-0.43720.1031-0.6152.4194-0.62590.62781.1904-0.6882.5411-53.161-47.4845146.7455
3480.09020.2795-0.39640.8468-1.2251.768-0.7235-0.2723-0.6011-0.1135-0.52460.8406-0.1997-0.2145-1.02261.2198-0.37360.30590.8074-0.65431.9549-44.4514-44.2601146.37
3490.18040.0088-0.14460.5814-0.01760.25140.06530.08350.1244-0.0286-0.106-0.1638-0.21520.0024-0.30.62910.56730.06760.476-0.29431.26698.9945-32.2113118.4901
3500.01720.0276-0.0110.0377-0.01590.01340.23150.244-0.029-0.16280.26260.1354-0.13050.18470.00121.76110.64320.25911.4792-0.31841.414120.9565-43.5141109.0288
3510.0367-0.0619-0.05010.1120.09250.0731-0.2879-0.09390.36480.2014-0.16690.2128-0.3844-0.2305-0.0011.01880.11820.08890.9244-0.35662.034716.6147-35.8956119.32
3520.0295-0.01860.01960.0177-0.00740.0152-0.0053-0.1986-0.18360.47010.21460.214-0.7634-0.0366-0.00040.89960.14540.06521.1541-0.01281.2399.1186-30.0767131.3501
3530.6299-0.32750.15290.1635-0.1320.93970.0368-0.0852-0.2331-0.13150.14520.14930.16860.03780.62380.74040.80710.02691.4223-0.6061.8949.2745-45.1345122.6993
3540.0305-0.0067-0.04950.0295-0.00230.0650.1280.0344-0.23-0.76640.3735-0.30160.1404-0.09150.00051.21570.11720.18381.1973-0.45781.903710.0692-50.1877120.7084
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3560.1838-0.1736-0.16350.3380.07850.1772-0.1909-0.14450.06550.0024-0.029-0.32120.31390.0132-0.14111.20220.32770.10251.0534-0.77772.581918.7757-50.8558113.2439
3570.04050.0312-0.00930.1594-0.09860.05510.56480.0062-0.3988-0.4225-0.18790.15980.28790.3182-0.00021.17240.2288-0.18491.0087-0.48481.48264.2109-36.0772130.121
3580.01940.0289-0.00310.05240.03470.01940.00970.6921-0.30220.32110.0019-0.2090.08390.1501-0.00031.18290.2148-0.13090.816-0.41661.313710.8626-42.2427113.1599
3590.0188-0.0025-0.01680.01670.01310.01830.09630.11550.21350.1256-0.11210.21760.13050.11850.00021.7902-0.33420.1531.3042-0.05770.732427.5848-57.581398.2941
3600.51030.0198-0.16470.66330.50470.38220.318-0.27430.3278-0.3871-0.18870.04940.6999-0.3542-0.00070.3593-0.0591-0.0630.34890.09880.24657.0452-108.531982.2315
3610.50320.3997-0.14560.3907-0.2940.36980.1263-0.3607-0.41940.3417-0.01320.010.0571-0.123200.5534-0.1263-0.06970.53220.03520.649356.5988-121.611171.8982
3620.01480.00410.01110.00810.01670.012-0.21650.1137-0.3171-0.6789-0.35780.44180.50360.0788-0.00211.26560.2824-0.20061.40930.06951.232572.8826-138.158673.2915
3630.29920.276-0.14750.3444-0.31310.7489-0.02570.0057-0.459-0.3591-0.1964-0.14681.0338-0.6067-0.14340.4469-0.034-0.01990.4668-0.04970.449559.7452-116.80875.138
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3660.01740.0211-0.01650.0237-0.02050.0121-0.19650.0909-0.16720.21270.2340.39110.04920.28130.00011.3336-0.64450.04331.1729-0.48291.167570.1841-137.467155.6846
3670.15080.0839-0.06920.0465-0.04620.02930.1276-0.5342-0.2198-0.03450.4995-0.37710.23310.97930.00270.66320.0281-0.05550.6776-0.18180.546469.8531-113.594149.9096
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3690.44970.20850.2860.2356-0.15170.48880.0845-0.06940.0024-0.0672-0.28660.29080.10240.270100.5566-0.03970.08280.8004-0.09430.387761.7155-116.763855.8825
3700.68550.2360.25730.09020.13940.26370.2373-0.2426-0.1303-0.4808-0.17290.1317-0.3162-0.14060.7630.5027-0.2115-0.22960.924-0.3354-0.118474.2861-99.296557.9341
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3720.4386-0.1287-0.24991.16531.56262.10790.3672-0.50160.21010.2530.5396-0.4684-0.03120.85690.41320.9473-0.1557-0.00960.75310.10110.184478.1907-96.129669.5247
3730.3374-0.32910.22640.33140.04390.46180.1420.0899-0.5020.125-0.0189-0.27730.60030.38280.01250.59190.0772-0.10940.5955-0.05990.474776.843-113.617172.9451
3740.04070.0132-0.03170.0182-0.01420.0194-0.5815-0.1908-0.3297-0.13360.45870.6958-0.3511-0.088-0.00092.29580.46130.0581.0838-0.29662.497682.3617-136.996564.4117
3751.5775-0.77651.45610.9935-0.93831.51180.20470.2695-0.50450.10260.01710.36850.52940.90780.46530.4532-0.22610.15710.7112-0.01160.214574.0706-108.894371.0565
3760.21090.02410.09330.0856-0.00950.03560.5560.25480.1842-0.5394-0.5213-0.00650.52290.0491-0.00070.6850.02260.09960.5847-0.00780.494178.3174-112.754862.7847
3770.0679-0.53860.00744.29840.04021.47190.2066-0.0910.11210.5933-0.5236-0.06020.1496-0.2092-0.44970.3452-0.0588-0.07790.66860.17920.35878.8705-105.08698.893
3780.01980.0248-0.00690.0270.00840.0182-0.2252-0.1257-0.09880.18970.031-0.2907-0.02790.3835-00.77130.1163-0.13471.10150.24380.974381.4603-107.7645117.8258
3790.00030.0067-0.04570.0712-0.15150.12980.4621-0.0592-0.0437-0.1085-0.4829-0.3243-0.10290.2313-0.00020.35090.04760.0490.69150.03640.604871.6258-101.2409101.452
3800.0060.014-0.06012.4941-0.83151.90590.0776-0.5466-0.51160.83760.1769-0.1087-0.53950.26180.12580.3782-0.1725-0.11610.58790.10440.750765.4331-108.5952110.8276
3810.12420.01850.02710.06920.09480.1069-0.1739-0.68060.3556-0.32180.3785-0.42730.0160.14820.00060.55530.00430.0690.8897-0.06270.534473.8819-95.4237106.3155
3820.53230.20570.41530.11160.14320.34730.3938-0.13510.10440.2620.25720.2219-0.06740.27920.0580.7854-0.41420.22421.28780.02060.858973.0664-108.6272119.834
3830.1614-0.059-0.16650.01230.04530.1642-0.13390.3864-0.0652-0.0476-0.3001-0.2402-0.24660.12-0.00060.4838-0.053-0.00790.55240.09380.460167.3766-102.432494.6499
3840.2339-0.09450.53360.68790.52812.0651-0.0439-0.262-0.27170.38440.1063-0.41440.40870.14030.31990.31740.3126-0.12590.65650.84950.813477.8749-112.1585111.6669
3850.01230.06150.04010.29990.19870.13210.0230.2244-0.13260.2365-0.09790.16590.0964-0.00120.10332.15040.13481.62933.42470.09653.603481.2446-115.2999134.6202
3860.03980.0737-0.10440.1522-0.22410.32840.25460.17820.0385-0.1827-0.1551-0.34560.16940.23530.00921.0668-0.32650.22671.093-0.22540.482584.8522-106.167236.8828
3870.0873-0.02020.01630.207-0.13540.0753-0.49850.4008-0.3353-0.0628-0.012-0.307-0.09740.3229-0.0071.0539-0.1270.30341.56140.05370.771789.7974-101.160934.4778
3880.00330.0052-0.00450.02020.02120.02070.44430.16480.1534-0.00860.06160.4224-0.1604-0.0010.00040.947-0.20370.40491.4572-0.00590.993895.2857-100.558143.8404
3890.08910.0489-0.08270.0329-0.04460.072-0.2926-0.6498-0.7863-0.42170.3797-0.1625-0.68790.050901.22650.05960.31941.32340.16721.172997.7478-98.109641.3213
3900.0102-0.0550.01490.3588-0.08820.0233-0.85810.1459-0.17750.3530.0537-0.5315-0.6773-1.0031-0.0151.0764-0.08490.35821.2511-0.21311.007596.3553-98.914634.2227
3910.4652-0.37080.02880.73020.00460.0298-0.86080.3905-0.5632-0.02190.0784-0.2064-0.6480.06-0.24751.04370.00590.21851.05210.02170.513286.1038-100.888344.6847
3920.44130.0742-0.25820.0099-0.04530.1537-0.2038-0.0686-0.0347-0.13470.0031-0.2987-0.19620.1121-0.1560.68670.00410.35682.52650.02472.0581117.5705-112.232726.6252
3931.56061.0267-0.76521.0635-0.09340.71580.6770.42920.0339-0.41770.34030.74770.7001-0.80091.03321.1224-0.2286-0.63571.0670.00221.20128.924-124.96952.0735
3940.0156-0.02810.03040.4967-0.10540.00090.27440.3402-0.6639-0.21830.22840.19510.8049-0.33290.44521.3706-0.3366-1.49730.596-0.66451.014329.1893-122.058652.7499
39530.44280.77070.06580.1130.1992-0.2432-0.56120.49270.4989-0.25990.42820.72370.4983-0.26730.957-0.05030.22031.0466-0.20520.53314.514-4.582328.9936
3960.2872-0.12610.14080.0398-0.15280.52060.2068-0.1450.1755-0.6128-0.08650.4367-0.2959-0.1899-0.01470.54-0.0775-0.05330.28510.14280.52390.7504-1.19589.3845
3970.2617-0.09530.15780.13160.0510.45170.0181-0.0048-0.00470.0770.11060.08990.28540.03520.10242.0008-0.094-0.3030.45970.21981.026110.34536.3682-16.7145
3980.1822-0.007-0.1446-0.0056-0.00670.0755-0.4387-0.1526-0.3003-0.11890.13530.22670.2029-0.0248-0.00630.70540.0767-0.07540.47390.13380.5792-6.17699.97371.3354
3990.49230.38980.42520.30190.33360.36570.62150.46460.1956-0.48780.2343-0.20180.41660.49630.11231.28010.2370.27060.83890.15530.670917.97497.2366-18.462
4000.0897-0.12490.1310.2057-0.12570.1936-0.13360.2369-0.2390.18820.19280.41910.0948-0.10030.22490.2102-0.03530.22690.43360.01020.83194.678310.17333.9995
4010.18690.07420.20160.51460.93631.99970.20140.40330.1944-0.40630.23630.6564-0.66270.2560.24990.4993-0.0411-0.12320.28110.14630.60071.67652.38584.562
4020.04290.0289-0.00010.0197-0.00030.006-0.2384-0.0696-0.05970.0918-0.08790.20980.8108-0.5187-0.00131.21320.38730.10941.1472-0.25960.9793-11.934515.456223.9671
4030.4950.2625-0.45130.4544-0.10630.3549-0.06030.11230.4604-0.1648-0.03410.3271-0.14680.3893-0.02280.49670.0455-0.07080.23520.18720.4532-2.083425.90389.8253
4040.42160.10650.02770.2588-0.11570.0645-0.00720.16750.3159-0.16290.22510.1875-0.5793-0.1518-0.0440.8715-0.1404-0.05820.25490.24460.864913.367628.65535.8586
4050.0086-0.0075-0.00160.0052-0.00260.0004-0.1870.2587-0.2567-0.11940.21880.21790.18440.0119-0.00031.85680.2661-0.0431.60710.54251.380714.015819.9706-19.1477
4060.51560.26930.06820.47010.17590.08550.239-0.15640.6543-0.11510.50260.2986-0.59060.17511.22620.5635-0.0955-0.1539-0.0686-0.07060.87397.48324.16439.6405
4070.61890.6405-0.39130.8099-0.65130.9747-0.41130.16180.3681-0.39720.37360.32550.4246-0.2594-0.16840.5662-0.05110.09060.25950.14021.0351.449423.08922.6555
4080.0649-0.15410.01810.5127-0.19490.17050.2366-0.55120.35140.4081-0.4034-0.3018-0.07290.0488-0.63770.181-0.31310.12810.4083-0.0140.805517.276518.811124.1505
4090.6191-0.07450.13621.27620.41660.3672-0.4183-0.0177-0.14590.42640.376-0.3950.23330.24380.09960.4182-0.0138-0.08740.270.11560.70121.041313.59318.6515
4103.32550.75861.83990.4975-0.2672.4916-0.18260.3132-0.591-0.18810.5828-0.20560.2546-0.00681.18350.96-0.10990.60710.4269-0.06021.119426.974810.2581-8.7272
4110.13660.12650.14340.3459-0.0720.2148-0.19110.3581-0.4886-0.5438-0.815-0.46370.14190.6152-0.01690.39540.07610.00460.43050.03790.59919.30490.895212.5144
4120.10640.0974-0.01970.0795-0.02830.24880.196-0.1097-0.06910.08790.15720.2716-0.02080.00680.33931.0124-0.67050.53680.39270.03370.773724.841316.2087-14.4859
4130.9660.38410.05270.1171-0.01060.00690.14950.4222-0.39430.4997-0.0033-0.10590.0642-0.09570.12740.41950.0725-0.11480.32010.00780.328517.35988.445112.3361
4140.1752-0.2908-0.00080.5436-0.27210.8496-0.3943-0.1576-0.02510.17530.3866-0.5502-0.37460.55150.04930.3572-0.0935-0.05790.5449-0.03370.721721.326116.485510.0184
4151.9316-0.3093-0.77120.0777-0.01781.13820.0757-0.04260.4366-0.37170.37630.4150.2891-0.46360.6660.6315-0.3410.39590.23510.56860.813921.5448-19.84313.1896
4160.4113-0.12160.2650.2199-0.02510.18750.5046-0.014-0.0977-0.19220.4067-0.36320.63410.11660.05791.03050.27990.01830.49320.09910.642723.7308-38.17627.1314
4171.4407-0.5495-0.2520.5660.01940.07030.09180.2968-0.44640.1839-0.24640.6564-0.8030.2948-0.08720.5854-0.0927-0.09260.48420.08660.551614.3208-23.187416.4812
4180.0191-0.0204-0.01090.02310.01020.0084-0.27340.1809-0.0670.21760.2067-0.1072-0.2228-0.3687-0.08771.5013-0.3308-0.4091.1850.05230.49558.7028-27.5357-0.5223
4190.60830.16470.82385.70451.91461.62320.03410.3804-0.25730.724-0.1175-0.08480.3705-0.5741-0.25960.25230.0923-0.13780.4917-0.05350.66738.0659-33.721313.34
4200.75550.26270.28240.27910.09870.8934-0.28620.02880.0113-0.163-0.3125-0.3976-0.47580.6264-1.53110.6064-0.06910.249-0.13230.70520.112316.5724-28.873521.3444
4210.0293-0.153-0.02210.82770.06280.65120.12110.2166-0.26230.2434-0.31260.17660.2993-0.3898-0.90950.3526-0.0951-0.19450.9823-0.26340.886315.3171-39.8836.1748
4221.74430.30380.6520.06220.10920.2453-0.06340.2120.18430.7468-0.2492-0.3457-0.50210.164-0.38760.5926-0.0348-0.15130.25940.1230.470711.8176-21.34213.7054
4230.4068-0.8355-0.4962.07871.23650.8384-0.14660.3954-0.2265-0.5551-0.48680.4804-0.14270.0268-0.04410.36820.01990.10540.4437-0.0670.365512.9227-18.764613.4561
4240.00970.0017-0.00760.02150.00480.00340.0828-0.2950.0056-0.0261-0.03320.0920.291-0.22850.00011.67960.1643-0.17680.9596-0.09991.061523.8674-53.8868-2.8161
Refinement TLS group
IDRefine-IDRefine TLS-IDSelection details
1X-RAY DIFFRACTION1chain '0' and (resid 1 through 13 )
2X-RAY DIFFRACTION2chain '0' and (resid 14 through 33 )
3X-RAY DIFFRACTION3chain '0' and (resid 34 through 70 )
4X-RAY DIFFRACTION4chain '0' and (resid 71 through 88 )
5X-RAY DIFFRACTION5chain '0' and (resid 89 through 107 )
6X-RAY DIFFRACTION6chain '1' and (resid 2 through 33 )
7X-RAY DIFFRACTION7chain '1' and (resid 34 through 54 )
8X-RAY DIFFRACTION8chain '1' and (resid 55 through 70 )
9X-RAY DIFFRACTION9chain '1' and (resid 71 through 105 )
10X-RAY DIFFRACTION10chain '2' and (resid 4 through 98 )
11X-RAY DIFFRACTION11chain '2' and (resid 99 through 113 )
12X-RAY DIFFRACTION12chain '2' and (resid 114 through 157 )
13X-RAY DIFFRACTION13chain '3' and (resid 6 through 21 )
14X-RAY DIFFRACTION14chain '3' and (resid 22 through 38 )
15X-RAY DIFFRACTION15chain '3' and (resid 39 through 66 )
16X-RAY DIFFRACTION16chain '3' and (resid 67 through 75 )
17X-RAY DIFFRACTION17chain '3' and (resid 76 through 98 )
18X-RAY DIFFRACTION18chain '3' and (resid 99 through 106 )
19X-RAY DIFFRACTION19chain '3' and (resid 107 through 113 )
20X-RAY DIFFRACTION20chain '3' and (resid 114 through 126 )
21X-RAY DIFFRACTION21chain '3' and (resid 127 through 157 )
22X-RAY DIFFRACTION22chain '4' and (resid 3 through 12 )
23X-RAY DIFFRACTION23chain '4' and (resid 13 through 32 )
24X-RAY DIFFRACTION24chain '4' and (resid 33 through 46 )
25X-RAY DIFFRACTION25chain '4' and (resid 47 through 65 )
26X-RAY DIFFRACTION26chain '4' and (resid 66 through 74 )
27X-RAY DIFFRACTION27chain '4' and (resid 75 through 99 )
28X-RAY DIFFRACTION28chain '4' and (resid 100 through 114 )
29X-RAY DIFFRACTION29chain '4' and (resid 115 through 136 )
30X-RAY DIFFRACTION30chain '4' and (resid 137 through 157 )
31X-RAY DIFFRACTION31chain '5' and (resid 1 through 71 )
32X-RAY DIFFRACTION32chain '5' and (resid 72 through 88 )
33X-RAY DIFFRACTION33chain '5' and (resid 89 through 108 )
34X-RAY DIFFRACTION34chain '6' and (resid 1 through 13 )
35X-RAY DIFFRACTION35chain '6' and (resid 14 through 19 )
36X-RAY DIFFRACTION36chain '6' and (resid 20 through 40 )
37X-RAY DIFFRACTION37chain '6' and (resid 41 through 54 )
38X-RAY DIFFRACTION38chain '6' and (resid 55 through 70 )
39X-RAY DIFFRACTION39chain '6' and (resid 71 through 78 )
40X-RAY DIFFRACTION40chain '6' and (resid 79 through 88 )
41X-RAY DIFFRACTION41chain '6' and (resid 89 through 96 )
42X-RAY DIFFRACTION42chain '6' and (resid 97 through 107 )
43X-RAY DIFFRACTION43chain '7' and (resid 1 through 15 )
44X-RAY DIFFRACTION44chain '7' and (resid 16 through 24 )
45X-RAY DIFFRACTION45chain '7' and (resid 25 through 42 )
46X-RAY DIFFRACTION46chain '7' and (resid 43 through 57 )
47X-RAY DIFFRACTION47chain '7' and (resid 58 through 67 )
48X-RAY DIFFRACTION48chain '7' and (resid 68 through 87 )
49X-RAY DIFFRACTION49chain '7' and (resid 88 through 107 )
50X-RAY DIFFRACTION50chain 'A' and (resid 2 through 12 )
51X-RAY DIFFRACTION51chain 'A' and (resid 13 through 67 )
52X-RAY DIFFRACTION52chain 'A' and (resid 68 through 99 )
53X-RAY DIFFRACTION53chain 'A' and (resid 100 through 112 )
54X-RAY DIFFRACTION54chain 'A' and (resid 113 through 157 )
55X-RAY DIFFRACTION55chain 'B' and (resid 5 through 12 )
56X-RAY DIFFRACTION56chain 'B' and (resid 13 through 53 )
57X-RAY DIFFRACTION57chain 'B' and (resid 54 through 98 )
58X-RAY DIFFRACTION58chain 'B' and (resid 99 through 113 )
59X-RAY DIFFRACTION59chain 'B' and (resid 114 through 136 )
60X-RAY DIFFRACTION60chain 'B' and (resid 137 through 157 )
61X-RAY DIFFRACTION61chain 'C' and (resid 5 through 12 )
62X-RAY DIFFRACTION62chain 'C' and (resid 13 through 46 )
63X-RAY DIFFRACTION63chain 'C' and (resid 47 through 66 )
64X-RAY DIFFRACTION64chain 'C' and (resid 67 through 74 )
65X-RAY DIFFRACTION65chain 'C' and (resid 75 through 83 )
66X-RAY DIFFRACTION66chain 'C' and (resid 84 through 99 )
67X-RAY DIFFRACTION67chain 'C' and (resid 100 through 113 )
68X-RAY DIFFRACTION68chain 'C' and (resid 114 through 126 )
69X-RAY DIFFRACTION69chain 'C' and (resid 127 through 136 )
70X-RAY DIFFRACTION70chain 'C' and (resid 137 through 157 )
71X-RAY DIFFRACTION71chain 'D' and (resid 1 through 8 )
72X-RAY DIFFRACTION72chain 'D' and (resid 9 through 16 )
73X-RAY DIFFRACTION73chain 'D' and (resid 17 through 28 )
74X-RAY DIFFRACTION74chain 'D' and (resid 29 through 40 )
75X-RAY DIFFRACTION75chain 'D' and (resid 41 through 54 )
76X-RAY DIFFRACTION76chain 'D' and (resid 55 through 71 )
77X-RAY DIFFRACTION77chain 'D' and (resid 72 through 88 )
78X-RAY DIFFRACTION78chain 'D' and (resid 89 through 100 )
79X-RAY DIFFRACTION79chain 'D' and (resid 101 through 106 )
80X-RAY DIFFRACTION80chain 'E' and (resid 1 through 8 )
81X-RAY DIFFRACTION81chain 'E' and (resid 9 through 18 )
82X-RAY DIFFRACTION82chain 'E' and (resid 19 through 40 )
83X-RAY DIFFRACTION83chain 'E' and (resid 41 through 60 )
84X-RAY DIFFRACTION84chain 'E' and (resid 61 through 70 )
85X-RAY DIFFRACTION85chain 'E' and (resid 71 through 78 )
86X-RAY DIFFRACTION86chain 'E' and (resid 79 through 97 )
87X-RAY DIFFRACTION87chain 'E' and (resid 98 through 108 )
88X-RAY DIFFRACTION88chain 'F' and (resid 1 through 10 )
89X-RAY DIFFRACTION89chain 'F' and (resid 11 through 33 )
90X-RAY DIFFRACTION90chain 'F' and (resid 34 through 52 )
91X-RAY DIFFRACTION91chain 'F' and (resid 53 through 72 )
92X-RAY DIFFRACTION92chain 'F' and (resid 73 through 81 )
93X-RAY DIFFRACTION93chain 'F' and (resid 82 through 88 )
94X-RAY DIFFRACTION94chain 'F' and (resid 89 through 97 )
95X-RAY DIFFRACTION95chain 'F' and (resid 98 through 106 )
96X-RAY DIFFRACTION96chain 'G' and (resid 5 through 12 )
97X-RAY DIFFRACTION97chain 'G' and (resid 13 through 66 )
98X-RAY DIFFRACTION98chain 'G' and (resid 67 through 98 )
99X-RAY DIFFRACTION99chain 'G' and (resid 99 through 113 )
100X-RAY DIFFRACTION100chain 'G' and (resid 114 through 126 )
101X-RAY DIFFRACTION101chain 'G' and (resid 127 through 157 )
102X-RAY DIFFRACTION102chain 'H' and (resid 6 through 38 )
103X-RAY DIFFRACTION103chain 'H' and (resid 39 through 67 )
104X-RAY DIFFRACTION104chain 'H' and (resid 68 through 75 )
105X-RAY DIFFRACTION105chain 'H' and (resid 76 through 98 )
106X-RAY DIFFRACTION106chain 'H' and (resid 99 through 112 )
107X-RAY DIFFRACTION107chain 'H' and (resid 113 through 136 )
108X-RAY DIFFRACTION108chain 'H' and (resid 137 through 157 )
109X-RAY DIFFRACTION109chain 'I' and (resid 6 through 12 )
110X-RAY DIFFRACTION110chain 'I' and (resid 13 through 22 )
111X-RAY DIFFRACTION111chain 'I' and (resid 23 through 38 )
112X-RAY DIFFRACTION112chain 'I' and (resid 39 through 53 )
113X-RAY DIFFRACTION113chain 'I' and (resid 54 through 67 )
114X-RAY DIFFRACTION114chain 'I' and (resid 68 through 74 )
115X-RAY DIFFRACTION115chain 'I' and (resid 75 through 99 )
116X-RAY DIFFRACTION116chain 'I' and (resid 100 through 112 )
117X-RAY DIFFRACTION117chain 'I' and (resid 113 through 136 )
118X-RAY DIFFRACTION118chain 'I' and (resid 137 through 157 )
119X-RAY DIFFRACTION119chain 'J' and (resid 1 through 40 )
120X-RAY DIFFRACTION120chain 'J' and (resid 41 through 54 )
121X-RAY DIFFRACTION121chain 'J' and (resid 55 through 71 )
122X-RAY DIFFRACTION122chain 'J' and (resid 72 through 87 )
123X-RAY DIFFRACTION123chain 'J' and (resid 88 through 108 )
124X-RAY DIFFRACTION124chain 'K' and (resid 1 through 10 )
125X-RAY DIFFRACTION125chain 'K' and (resid 11 through 23 )
126X-RAY DIFFRACTION126chain 'K' and (resid 24 through 78 )
127X-RAY DIFFRACTION127chain 'K' and (resid 79 through 106 )
128X-RAY DIFFRACTION128chain 'L' and (resid 1 through 5 )
129X-RAY DIFFRACTION129chain 'L' and (resid 6 through 28 )
130X-RAY DIFFRACTION130chain 'L' and (resid 29 through 40 )
131X-RAY DIFFRACTION131chain 'L' and (resid 41 through 55 )
132X-RAY DIFFRACTION132chain 'L' and (resid 56 through 70 )
133X-RAY DIFFRACTION133chain 'L' and (resid 71 through 78 )
134X-RAY DIFFRACTION134chain 'L' and (resid 79 through 99 )
135X-RAY DIFFRACTION135chain 'L' and (resid 100 through 105 )
136X-RAY DIFFRACTION136chain 'L' and (resid 106 through 112 )
137X-RAY DIFFRACTION137chain 'M' and (resid 5 through 67 )
138X-RAY DIFFRACTION138chain 'M' and (resid 68 through 98 )
139X-RAY DIFFRACTION139chain 'M' and (resid 99 through 112 )
140X-RAY DIFFRACTION140chain 'M' and (resid 113 through 136 )
141X-RAY DIFFRACTION141chain 'M' and (resid 137 through 157 )
142X-RAY DIFFRACTION142chain 'N' and (resid 5 through 12 )
143X-RAY DIFFRACTION143chain 'N' and (resid 13 through 30 )
144X-RAY DIFFRACTION144chain 'N' and (resid 31 through 66 )
145X-RAY DIFFRACTION145chain 'N' and (resid 67 through 75 )
146X-RAY DIFFRACTION146chain 'N' and (resid 76 through 98 )
147X-RAY DIFFRACTION147chain 'N' and (resid 99 through 113 )
148X-RAY DIFFRACTION148chain 'N' and (resid 114 through 136 )
149X-RAY DIFFRACTION149chain 'N' and (resid 137 through 157 )
150X-RAY DIFFRACTION150chain 'O' and (resid 5 through 42 )
151X-RAY DIFFRACTION151chain 'O' and (resid 43 through 66 )
152X-RAY DIFFRACTION152chain 'O' and (resid 67 through 98 )
153X-RAY DIFFRACTION153chain 'O' and (resid 99 through 113 )
154X-RAY DIFFRACTION154chain 'O' and (resid 114 through 136 )
155X-RAY DIFFRACTION155chain 'O' and (resid 137 through 157 )
156X-RAY DIFFRACTION156chain 'P' and (resid 1 through 8 )
157X-RAY DIFFRACTION157chain 'P' and (resid 9 through 23 )
158X-RAY DIFFRACTION158chain 'P' and (resid 24 through 28 )
159X-RAY DIFFRACTION159chain 'P' and (resid 29 through 40 )
160X-RAY DIFFRACTION160chain 'P' and (resid 41 through 45 )
161X-RAY DIFFRACTION161chain 'P' and (resid 46 through 54 )
162X-RAY DIFFRACTION162chain 'P' and (resid 55 through 70 )
163X-RAY DIFFRACTION163chain 'P' and (resid 71 through 78 )
164X-RAY DIFFRACTION164chain 'P' and (resid 79 through 99 )
165X-RAY DIFFRACTION165chain 'P' and (resid 100 through 107 )
166X-RAY DIFFRACTION166chain 'Q' and (resid 1 through 10 )
167X-RAY DIFFRACTION167chain 'Q' and (resid 11 through 23 )
168X-RAY DIFFRACTION168chain 'Q' and (resid 24 through 54 )
169X-RAY DIFFRACTION169chain 'Q' and (resid 55 through 70 )
170X-RAY DIFFRACTION170chain 'Q' and (resid 71 through 78 )
171X-RAY DIFFRACTION171chain 'Q' and (resid 79 through 97 )
172X-RAY DIFFRACTION172chain 'Q' and (resid 98 through 112 )
173X-RAY DIFFRACTION173chain 'R' and (resid 1 through 10 )
174X-RAY DIFFRACTION174chain 'R' and (resid 11 through 23 )
175X-RAY DIFFRACTION175chain 'R' and (resid 24 through 33 )
176X-RAY DIFFRACTION176chain 'R' and (resid 34 through 42 )
177X-RAY DIFFRACTION177chain 'R' and (resid 43 through 54 )
178X-RAY DIFFRACTION178chain 'R' and (resid 55 through 60 )
179X-RAY DIFFRACTION179chain 'R' and (resid 61 through 70 )
180X-RAY DIFFRACTION180chain 'R' and (resid 71 through 89 )
181X-RAY DIFFRACTION181chain 'R' and (resid 90 through 96 )
182X-RAY DIFFRACTION182chain 'R' and (resid 97 through 102 )
183X-RAY DIFFRACTION183chain 'R' and (resid 103 through 107 )
184X-RAY DIFFRACTION184chain 'S' and (resid 4 through 12 )
185X-RAY DIFFRACTION185chain 'S' and (resid 13 through 98 )
186X-RAY DIFFRACTION186chain 'S' and (resid 99 through 112 )
187X-RAY DIFFRACTION187chain 'S' and (resid 113 through 136 )
188X-RAY DIFFRACTION188chain 'S' and (resid 137 through 157 )
189X-RAY DIFFRACTION189chain 'T' and (resid 2 through 12 )
190X-RAY DIFFRACTION190chain 'T' and (resid 13 through 67 )
191X-RAY DIFFRACTION191chain 'T' and (resid 68 through 75 )
192X-RAY DIFFRACTION192chain 'T' and (resid 76 through 98 )
193X-RAY DIFFRACTION193chain 'T' and (resid 99 through 112 )
194X-RAY DIFFRACTION194chain 'T' and (resid 113 through 136 )
195X-RAY DIFFRACTION195chain 'T' and (resid 137 through 157 )
196X-RAY DIFFRACTION196chain 'U' and (resid 8 through 53 )
197X-RAY DIFFRACTION197chain 'U' and (resid 54 through 74 )
198X-RAY DIFFRACTION198chain 'U' and (resid 75 through 99 )
199X-RAY DIFFRACTION199chain 'U' and (resid 100 through 113 )
200X-RAY DIFFRACTION200chain 'U' and (resid 114 through 136 )
201X-RAY DIFFRACTION201chain 'U' and (resid 137 through 157 )
202X-RAY DIFFRACTION202chain 'V' and (resid 1 through 8 )
203X-RAY DIFFRACTION203chain 'V' and (resid 9 through 71 )
204X-RAY DIFFRACTION204chain 'V' and (resid 72 through 106 )
205X-RAY DIFFRACTION205chain 'W' and (resid 1 through 5 )
206X-RAY DIFFRACTION206chain 'W' and (resid 6 through 13 )
207X-RAY DIFFRACTION207chain 'W' and (resid 14 through 33 )
208X-RAY DIFFRACTION208chain 'W' and (resid 34 through 40 )
209X-RAY DIFFRACTION209chain 'W' and (resid 41 through 60 )
210X-RAY DIFFRACTION210chain 'W' and (resid 61 through 70 )
211X-RAY DIFFRACTION211chain 'W' and (resid 71 through 99 )
212X-RAY DIFFRACTION212chain 'W' and (resid 100 through 106 )
213X-RAY DIFFRACTION213chain 'X' and (resid 1 through 16 )
214X-RAY DIFFRACTION214chain 'X' and (resid 17 through 40 )
215X-RAY DIFFRACTION215chain 'X' and (resid 41 through 54 )
216X-RAY DIFFRACTION216chain 'X' and (resid 55 through 64 )
217X-RAY DIFFRACTION217chain 'X' and (resid 65 through 78 )
218X-RAY DIFFRACTION218chain 'X' and (resid 79 through 100 )
219X-RAY DIFFRACTION219chain 'X' and (resid 101 through 107 )
220X-RAY DIFFRACTION220chain 'Y' and (resid 5 through 12 )
221X-RAY DIFFRACTION221chain 'Y' and (resid 13 through 22 )
222X-RAY DIFFRACTION222chain 'Y' and (resid 23 through 67 )
223X-RAY DIFFRACTION223chain 'Y' and (resid 68 through 75 )
224X-RAY DIFFRACTION224chain 'Y' and (resid 76 through 98 )
225X-RAY DIFFRACTION225chain 'Y' and (resid 99 through 112 )
226X-RAY DIFFRACTION226chain 'Y' and (resid 113 through 126 )
227X-RAY DIFFRACTION227chain 'Y' and (resid 127 through 136 )
228X-RAY DIFFRACTION228chain 'Y' and (resid 137 through 157 )
229X-RAY DIFFRACTION229chain 'Z' and (resid 6 through 22 )
230X-RAY DIFFRACTION230chain 'Z' and (resid 23 through 38 )
231X-RAY DIFFRACTION231chain 'Z' and (resid 39 through 53 )
232X-RAY DIFFRACTION232chain 'Z' and (resid 54 through 66 )
233X-RAY DIFFRACTION233chain 'Z' and (resid 67 through 75 )
234X-RAY DIFFRACTION234chain 'Z' and (resid 76 through 98 )
235X-RAY DIFFRACTION235chain 'Z' and (resid 99 through 113 )
236X-RAY DIFFRACTION236chain 'Z' and (resid 114 through 136 )
237X-RAY DIFFRACTION237chain 'Z' and (resid 137 through 157 )
238X-RAY DIFFRACTION238chain 'a' and (resid 4 through 38 )
239X-RAY DIFFRACTION239chain 'a' and (resid 39 through 74 )
240X-RAY DIFFRACTION240chain 'a' and (resid 75 through 99 )
241X-RAY DIFFRACTION241chain 'a' and (resid 100 through 112 )
242X-RAY DIFFRACTION242chain 'a' and (resid 113 through 157 )
243X-RAY DIFFRACTION243chain 'b' and (resid 1 through 8 )
244X-RAY DIFFRACTION244chain 'b' and (resid 9 through 23 )
245X-RAY DIFFRACTION245chain 'b' and (resid 24 through 40 )
246X-RAY DIFFRACTION246chain 'b' and (resid 41 through 54 )
247X-RAY DIFFRACTION247chain 'b' and (resid 55 through 71 )
248X-RAY DIFFRACTION248chain 'b' and (resid 72 through 78 )
249X-RAY DIFFRACTION249chain 'b' and (resid 79 through 97 )
250X-RAY DIFFRACTION250chain 'b' and (resid 98 through 105 )
251X-RAY DIFFRACTION251chain 'b' and (resid 106 through 112 )
252X-RAY DIFFRACTION252chain 'c' and (resid 1 through 8 )
253X-RAY DIFFRACTION253chain 'c' and (resid 9 through 17 )
254X-RAY DIFFRACTION254chain 'c' and (resid 18 through 28 )
255X-RAY DIFFRACTION255chain 'c' and (resid 29 through 40 )
256X-RAY DIFFRACTION256chain 'c' and (resid 41 through 46 )
257X-RAY DIFFRACTION257chain 'c' and (resid 47 through 54 )
258X-RAY DIFFRACTION258chain 'c' and (resid 55 through 60 )
259X-RAY DIFFRACTION259chain 'c' and (resid 61 through 70 )
260X-RAY DIFFRACTION260chain 'c' and (resid 71 through 78 )
261X-RAY DIFFRACTION261chain 'c' and (resid 79 through 88 )
262X-RAY DIFFRACTION262chain 'c' and (resid 89 through 97 )
263X-RAY DIFFRACTION263chain 'c' and (resid 98 through 105 )
264X-RAY DIFFRACTION264chain 'c' and (resid 106 through 112 )
265X-RAY DIFFRACTION265chain 'd' and (resid 1 through 23 )
266X-RAY DIFFRACTION266chain 'd' and (resid 24 through 40 )
267X-RAY DIFFRACTION267chain 'd' and (resid 41 through 63 )
268X-RAY DIFFRACTION268chain 'd' and (resid 64 through 96 )
269X-RAY DIFFRACTION269chain 'd' and (resid 97 through 105 )
270X-RAY DIFFRACTION270chain 'd' and (resid 106 through 112 )
271X-RAY DIFFRACTION271chain 'e' and (resid 5 through 12 )
272X-RAY DIFFRACTION272chain 'e' and (resid 13 through 22 )
273X-RAY DIFFRACTION273chain 'e' and (resid 23 through 38 )
274X-RAY DIFFRACTION274chain 'e' and (resid 39 through 53 )
275X-RAY DIFFRACTION275chain 'e' and (resid 54 through 74 )
276X-RAY DIFFRACTION276chain 'e' and (resid 75 through 99 )
277X-RAY DIFFRACTION277chain 'e' and (resid 100 through 113 )
278X-RAY DIFFRACTION278chain 'e' and (resid 114 through 136 )
279X-RAY DIFFRACTION279chain 'e' and (resid 137 through 157 )
280X-RAY DIFFRACTION280chain 'f' and (resid 2 through 20 )
281X-RAY DIFFRACTION281chain 'f' and (resid 21 through 30 )
282X-RAY DIFFRACTION282chain 'f' and (resid 31 through 67 )
283X-RAY DIFFRACTION283chain 'f' and (resid 68 through 75 )
284X-RAY DIFFRACTION284chain 'f' and (resid 76 through 98 )
285X-RAY DIFFRACTION285chain 'f' and (resid 99 through 112 )
286X-RAY DIFFRACTION286chain 'f' and (resid 113 through 126 )
287X-RAY DIFFRACTION287chain 'f' and (resid 127 through 157 )
288X-RAY DIFFRACTION288chain 'g' and (resid 5 through 38 )
289X-RAY DIFFRACTION289chain 'g' and (resid 39 through 53 )
290X-RAY DIFFRACTION290chain 'g' and (resid 54 through 66 )
291X-RAY DIFFRACTION291chain 'g' and (resid 67 through 74 )
292X-RAY DIFFRACTION292chain 'g' and (resid 75 through 99 )
293X-RAY DIFFRACTION293chain 'g' and (resid 100 through 113 )
294X-RAY DIFFRACTION294chain 'g' and (resid 114 through 136 )
295X-RAY DIFFRACTION295chain 'g' and (resid 137 through 157 )
296X-RAY DIFFRACTION296chain 'h' and (resid 1 through 8 )
297X-RAY DIFFRACTION297chain 'h' and (resid 9 through 40 )
298X-RAY DIFFRACTION298chain 'h' and (resid 41 through 48 )
299X-RAY DIFFRACTION299chain 'h' and (resid 49 through 70 )
300X-RAY DIFFRACTION300chain 'h' and (resid 71 through 78 )
301X-RAY DIFFRACTION301chain 'h' and (resid 79 through 89 )
302X-RAY DIFFRACTION302chain 'h' and (resid 90 through 97 )
303X-RAY DIFFRACTION303chain 'h' and (resid 98 through 105 )
304X-RAY DIFFRACTION304chain 'h' and (resid 106 through 112 )
305X-RAY DIFFRACTION305chain 'i' and (resid 1 through 33 )
306X-RAY DIFFRACTION306chain 'i' and (resid 34 through 43 )
307X-RAY DIFFRACTION307chain 'i' and (resid 44 through 64 )
308X-RAY DIFFRACTION308chain 'i' and (resid 65 through 78 )
309X-RAY DIFFRACTION309chain 'i' and (resid 79 through 104 )
310X-RAY DIFFRACTION310chain 'i' and (resid 105 through 112 )
311X-RAY DIFFRACTION311chain 'j' and (resid 1 through 39 )
312X-RAY DIFFRACTION312chain 'j' and (resid 40 through 49 )
313X-RAY DIFFRACTION313chain 'j' and (resid 50 through 79 )
314X-RAY DIFFRACTION314chain 'j' and (resid 80 through 88 )
315X-RAY DIFFRACTION315chain 'j' and (resid 89 through 105 )
316X-RAY DIFFRACTION316chain 'k' and (resid 2 through 12 )
317X-RAY DIFFRACTION317chain 'k' and (resid 13 through 98 )
318X-RAY DIFFRACTION318chain 'k' and (resid 99 through 112 )
319X-RAY DIFFRACTION319chain 'k' and (resid 113 through 136 )
320X-RAY DIFFRACTION320chain 'k' and (resid 137 through 157 )
321X-RAY DIFFRACTION321chain 'l' and (resid 5 through 12 )
322X-RAY DIFFRACTION322chain 'l' and (resid 13 through 38 )
323X-RAY DIFFRACTION323chain 'l' and (resid 39 through 53 )
324X-RAY DIFFRACTION324chain 'l' and (resid 54 through 66 )
325X-RAY DIFFRACTION325chain 'l' and (resid 67 through 75 )
326X-RAY DIFFRACTION326chain 'l' and (resid 76 through 98 )
327X-RAY DIFFRACTION327chain 'l' and (resid 99 through 113 )
328X-RAY DIFFRACTION328chain 'l' and (resid 114 through 126 )
329X-RAY DIFFRACTION329chain 'l' and (resid 127 through 135 )
330X-RAY DIFFRACTION330chain 'l' and (resid 136 through 157 )
331X-RAY DIFFRACTION331chain 'm' and (resid 7 through 22 )
332X-RAY DIFFRACTION332chain 'm' and (resid 23 through 38 )
333X-RAY DIFFRACTION333chain 'm' and (resid 39 through 53 )
334X-RAY DIFFRACTION334chain 'm' and (resid 54 through 74 )
335X-RAY DIFFRACTION335chain 'm' and (resid 75 through 99 )
336X-RAY DIFFRACTION336chain 'm' and (resid 100 through 113 )
337X-RAY DIFFRACTION337chain 'm' and (resid 114 through 136 )
338X-RAY DIFFRACTION338chain 'm' and (resid 137 through 157 )
339X-RAY DIFFRACTION339chain 'n' and (resid 1 through 40 )
340X-RAY DIFFRACTION340chain 'n' and (resid 41 through 71 )
341X-RAY DIFFRACTION341chain 'n' and (resid 72 through 88 )
342X-RAY DIFFRACTION342chain 'n' and (resid 89 through 109 )
343X-RAY DIFFRACTION343chain 'o' and (resid 2 through 21 )
344X-RAY DIFFRACTION344chain 'o' and (resid 22 through 37 )
345X-RAY DIFFRACTION345chain 'o' and (resid 38 through 47 )
346X-RAY DIFFRACTION346chain 'o' and (resid 48 through 72 )
347X-RAY DIFFRACTION347chain 'o' and (resid 73 through 88 )
348X-RAY DIFFRACTION348chain 'o' and (resid 89 through 105 )
349X-RAY DIFFRACTION349chain 'p' and (resid 1 through 8 )
350X-RAY DIFFRACTION350chain 'p' and (resid 9 through 17 )
351X-RAY DIFFRACTION351chain 'p' and (resid 18 through 23 )
352X-RAY DIFFRACTION352chain 'p' and (resid 24 through 33 )
353X-RAY DIFFRACTION353chain 'p' and (resid 34 through 40 )
354X-RAY DIFFRACTION354chain 'p' and (resid 41 through 54 )
355X-RAY DIFFRACTION355chain 'p' and (resid 55 through 70 )
356X-RAY DIFFRACTION356chain 'p' and (resid 71 through 78 )
357X-RAY DIFFRACTION357chain 'p' and (resid 79 through 96 )
358X-RAY DIFFRACTION358chain 'p' and (resid 97 through 105 )
359X-RAY DIFFRACTION359chain 'p' and (resid 106 through 112 )
360X-RAY DIFFRACTION360chain 'q' and (resid 8 through 53 )
361X-RAY DIFFRACTION361chain 'q' and (resid 54 through 99 )
362X-RAY DIFFRACTION362chain 'q' and (resid 100 through 113 )
363X-RAY DIFFRACTION363chain 'q' and (resid 114 through 157 )
364X-RAY DIFFRACTION364chain 'r' and (resid 6 through 22 )
365X-RAY DIFFRACTION365chain 'r' and (resid 23 through 66 )
366X-RAY DIFFRACTION366chain 'r' and (resid 67 through 74 )
367X-RAY DIFFRACTION367chain 'r' and (resid 75 through 99 )
368X-RAY DIFFRACTION368chain 'r' and (resid 100 through 113 )
369X-RAY DIFFRACTION369chain 'r' and (resid 114 through 157 )
370X-RAY DIFFRACTION370chain 's' and (resid 6 through 22 )
371X-RAY DIFFRACTION371chain 's' and (resid 23 through 38 )
372X-RAY DIFFRACTION372chain 's' and (resid 39 through 53 )
373X-RAY DIFFRACTION373chain 's' and (resid 54 through 99 )
374X-RAY DIFFRACTION374chain 's' and (resid 100 through 113 )
375X-RAY DIFFRACTION375chain 's' and (resid 114 through 136 )
376X-RAY DIFFRACTION376chain 's' and (resid 137 through 157 )
377X-RAY DIFFRACTION377chain 't' and (resid 1 through 8 )
378X-RAY DIFFRACTION378chain 't' and (resid 9 through 17 )
379X-RAY DIFFRACTION379chain 't' and (resid 18 through 40 )
380X-RAY DIFFRACTION380chain 't' and (resid 41 through 54 )
381X-RAY DIFFRACTION381chain 't' and (resid 55 through 70 )
382X-RAY DIFFRACTION382chain 't' and (resid 71 through 78 )
383X-RAY DIFFRACTION383chain 't' and (resid 79 through 97 )
384X-RAY DIFFRACTION384chain 't' and (resid 98 through 105 )
385X-RAY DIFFRACTION385chain 't' and (resid 106 through 112 )
386X-RAY DIFFRACTION386chain 'u' and (resid 1 through 8 )
387X-RAY DIFFRACTION387chain 'u' and (resid 9 through 33 )
388X-RAY DIFFRACTION388chain 'u' and (resid 34 through 40 )
389X-RAY DIFFRACTION389chain 'u' and (resid 41 through 60 )
390X-RAY DIFFRACTION390chain 'u' and (resid 61 through 78 )
391X-RAY DIFFRACTION391chain 'u' and (resid 79 through 104 )
392X-RAY DIFFRACTION392chain 'u' and (resid 105 through 112 )
393X-RAY DIFFRACTION393chain 'v' and (resid 1 through 55 )
394X-RAY DIFFRACTION394chain 'v' and (resid 56 through 105 )
395X-RAY DIFFRACTION395chain 'w' and (resid 2 through 12 )
396X-RAY DIFFRACTION396chain 'w' and (resid 13 through 66 )
397X-RAY DIFFRACTION397chain 'w' and (resid 67 through 74 )
398X-RAY DIFFRACTION398chain 'w' and (resid 75 through 99 )
399X-RAY DIFFRACTION399chain 'w' and (resid 100 through 113 )
400X-RAY DIFFRACTION400chain 'w' and (resid 114 through 126 )
401X-RAY DIFFRACTION401chain 'w' and (resid 127 through 157 )
402X-RAY DIFFRACTION402chain 'x' and (resid 5 through 12 )
403X-RAY DIFFRACTION403chain 'x' and (resid 13 through 67 )
404X-RAY DIFFRACTION404chain 'x' and (resid 68 through 99 )
405X-RAY DIFFRACTION405chain 'x' and (resid 100 through 112 )
406X-RAY DIFFRACTION406chain 'x' and (resid 113 through 136 )
407X-RAY DIFFRACTION407chain 'x' and (resid 137 through 157 )
408X-RAY DIFFRACTION408chain 'y' and (resid 6 through 22 )
409X-RAY DIFFRACTION409chain 'y' and (resid 23 through 67 )
410X-RAY DIFFRACTION410chain 'y' and (resid 68 through 75 )
411X-RAY DIFFRACTION411chain 'y' and (resid 76 through 98 )
412X-RAY DIFFRACTION412chain 'y' and (resid 99 through 112 )
413X-RAY DIFFRACTION413chain 'y' and (resid 113 through 136 )
414X-RAY DIFFRACTION414chain 'y' and (resid 137 through 157 )
415X-RAY DIFFRACTION415chain 'z' and (resid 1 through 8 )
416X-RAY DIFFRACTION416chain 'z' and (resid 9 through 17 )
417X-RAY DIFFRACTION417chain 'z' and (resid 18 through 40 )
418X-RAY DIFFRACTION418chain 'z' and (resid 41 through 46 )
419X-RAY DIFFRACTION419chain 'z' and (resid 47 through 54 )
420X-RAY DIFFRACTION420chain 'z' and (resid 55 through 70 )
421X-RAY DIFFRACTION421chain 'z' and (resid 71 through 78 )
422X-RAY DIFFRACTION422chain 'z' and (resid 79 through 88 )
423X-RAY DIFFRACTION423chain 'z' and (resid 89 through 105 )
424X-RAY DIFFRACTION424chain 'z' and (resid 106 through 112 )

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