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- PDB-9cr9: Crystal structure of MA6 Fab in complex with PfCSP repeat region ... -
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Open data
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Basic information
Entry | Database: PDB / ID: 9cr9 | ||||||
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Title | Crystal structure of MA6 Fab in complex with PfCSP repeat region peptide NPNA3 | ||||||
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![]() | IMMUNE SYSTEM / circumsporozoite protein / PfCSP / CSP / protective / neutralizing / antibody / Fab | ||||||
Function / homology | : / side of membrane / plasma membrane / cytoplasm / Circumsporozoite protein![]() | ||||||
Biological species | ![]() ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Rush, S.A. / McLellan, J.S. | ||||||
Funding support | 1items
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![]() | ![]() Title: Repertoire, function, and structure of serological antibodies induced by the R21/Matrix-M malaria vaccine Authors: McDaniel, J.R. / Voss, W.N. / Bowyer, G. / Rush, S.A. / Spencer, A.J. / Bellamy, D. / Goike, J. / Gregory, S. / King, C.R. / McLellan, J.S. / Hill, A.V.S. / Georgiou, G. / Ewer, K.J. / Ippolito, G.C. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 367.1 KB | Display | ![]() |
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PDB format | ![]() | 296.7 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 438.3 KB | Display | ![]() |
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Full document | ![]() | 443.3 KB | Display | |
Data in XML | ![]() | 50.1 KB | Display | |
Data in CIF | ![]() | 72.3 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data | Similarity search - Function & homology ![]() |
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Links
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Assembly
Deposited unit | ![]()
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2 | ![]()
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Unit cell |
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Components
#1: Antibody | Mass: 25141.135 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() #2: Antibody | Mass: 23385.902 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() #3: Protein/peptide | Mass: 1207.210 Da / Num. of mol.: 2 / Fragment: residues 134-145 / Source method: obtained synthetically Source: (synth.) ![]() ![]() References: UniProt: P05691 #4: Water | ChemComp-HOH / | Has protein modification | Y | |
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-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.19 Å3/Da / Density % sol: 43.78 % |
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Crystal grow | Temperature: 293 K / Method: vapor diffusion, sitting drop / Details: 27% PEG3350, 3% MPD |
-Data collection
Diffraction | Mean temperature: 100 K / Serial crystal experiment: N |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: DECTRIS PILATUS3 X 6M / Detector: PIXEL / Date: Jun 22, 2019 |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 0.9795 Å / Relative weight: 1 |
Reflection | Resolution: 1.8→47.72 Å / Num. obs: 74608 / % possible obs: 93.33 % / Redundancy: 1.8 % / Biso Wilson estimate: 17.05 Å2 / CC1/2: 0.941 / Rmerge(I) obs: 0.077 / Rpim(I) all: 0.077 / Rrim(I) all: 0.1089 / Net I/σ(I): 5.93 |
Reflection shell | Resolution: 1.8→1.864 Å / Rmerge(I) obs: 0.4335 / Mean I/σ(I) obs: 2.14 / Num. unique obs: 7426 / CC1/2: 0.626 / Rpim(I) all: 0.4335 / Rrim(I) all: 0.613 / % possible all: 93.07 |
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Processing
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Refinement | Method to determine structure: ![]()
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Solvent computation | Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 1.8→47.72 Å
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Refine LS restraints |
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LS refinement shell |
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