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Open data
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Basic information
Entry | Database: PDB / ID: 9bvu | ||||||
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Title | NMR structure of TLP-2 in solution | ||||||
![]() | Temporin-1Tl | ||||||
![]() | ANTIVIRAL PROTEIN | ||||||
Function / homology | other organism cell membrane / killing of cells of another organism / defense response to bacterium / innate immune response / lipid binding / extracellular region / membrane / Temporin-1Tl![]() | ||||||
Biological species | Rana temporaria (common frog) | ||||||
Method | SOLUTION NMR / simulated annealing | ||||||
![]() | Jia, R. / McShan, A.C. | ||||||
Funding support | 1items
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![]() | ![]() Title: Design and Development of Temporin L Analogues to Inhibit the Main Protease of SARS-CoV-2 Authors: Jia, R. / McShan, A.C. | ||||||
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 61.8 KB | Display | ![]() |
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PDB format | ![]() | 45.1 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 413.2 KB | Display | ![]() |
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Full document | ![]() | 448.4 KB | Display | |
Data in XML | ![]() | 5.7 KB | Display | |
Data in CIF | ![]() | 7.4 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 9bvsC ![]() 9bvvC C: citing same article ( |
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Similar structure data | Similarity search - Function & homology ![]() |
Other databases |
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: Protein/peptide | Mass: 1904.217 Da / Num. of mol.: 1 / Source method: obtained synthetically / Source: (synth.) Rana temporaria (common frog) / References: UniProt: P57104 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||
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NMR experiment |
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Sample preparation
Details | Type: solution / Contents: 10 mg/mL TLP-2, 90% H2O/10% D2O / Label: TLP-2 / Solvent system: 90% H2O/10% D2O |
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Sample | Conc.: 10 mg/mL / Component: TLP-2 / Isotopic labeling: natural abundance |
Sample conditions | Ionic strength: 50 mM / Label: TLP-2_conditions / pH: 5 / Pressure: 1 atm / Temperature: 277.15 K |
-NMR measurement
NMR spectrometer | Type: Bruker AVANCE III HD / Manufacturer: Bruker / Model: AVANCE III HD / Field strength: 800 MHz |
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Processing
NMR software |
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Refinement | Method: simulated annealing / Software ordinal: 1 | ||||||||||||
NMR representative | Selection criteria: lowest energy | ||||||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 200 / Conformers submitted total number: 10 |