登録情報 | データベース: PDB / ID: 8yfm |
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タイトル | Crystal structure of FIP200 claw/TNIP1_FIR_pS122 |
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要素 | - RB1-inducible coiled-coil protein 1
- TNIP1_FIR_pS122 peptide
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キーワード | PROTEIN BINDING / phosphorylation / selective mitophagy |
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機能・相同性 | 機能・相同性情報
positive regulation of protein deubiquitination / regulation of protein lipidation / ribophagy / glycoprotein biosynthetic process / Atg1/ULK1 kinase complex / glycophagy / phagophore assembly site membrane / piecemeal microautophagy of the nucleus / phagophore assembly site / mitogen-activated protein kinase binding ...positive regulation of protein deubiquitination / regulation of protein lipidation / ribophagy / glycoprotein biosynthetic process / Atg1/ULK1 kinase complex / glycophagy / phagophore assembly site membrane / piecemeal microautophagy of the nucleus / phagophore assembly site / mitogen-activated protein kinase binding / reticulophagy / MyD88-dependent toll-like receptor signaling pathway / leukocyte cell-cell adhesion / negative regulation of viral genome replication / Macroautophagy / autophagosome membrane / positive regulation of cell size / autophagosome assembly / positive regulation of autophagy / extrinsic apoptotic signaling pathway / negative regulation of canonical NF-kappaB signal transduction / protein-membrane adaptor activity / liver development / negative regulation of extrinsic apoptotic signaling pathway / positive regulation of JNK cascade / negative regulation of ERK1 and ERK2 cascade / defense response / autophagy / positive regulation of inflammatory response / Ovarian tumor domain proteases / heart development / nuclear membrane / cellular response to lipopolysaccharide / molecular adaptor activity / lysosome / translation / positive regulation of protein phosphorylation / inflammatory response / negative regulation of cell population proliferation / endoplasmic reticulum membrane / regulation of transcription by RNA polymerase II / protein kinase binding / positive regulation of transcription by RNA polymerase II / nucleoplasm / identical protein binding / cytosol類似検索 - 分子機能 Autophagy-related protein 11, C-terminal / Autophagy-related protein 11 / Autophagy-related protein 11類似検索 - ドメイン・相同性 TNFAIP3-interacting protein 1 / RB1-inducible coiled-coil protein 1類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.5 Å |
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データ登録者 | Lv, M.Q. / Wu, S.M. |
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資金援助 | 中国, 1件 組織 | 認可番号 | 国 |
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National Natural Science Foundation of China (NSFC) | 32293210, 32293213, 32000882, 12374220, 32100958 and 32090040 | 中国 |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2024 タイトル: Structural basis for TNIP1 binding to FIP200 during mitophagy. 著者: Wu, S. / Li, M. / Wang, L. / Yang, L. / Cui, J. / Li, F. / Wang, Q. / Shi, Y. / Lv, M. |
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履歴 | 登録 | 2024年2月24日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2024年8月14日 | Provider: repository / タイプ: Initial release |
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