Entry | Database: PDB / ID: 8uk7 |
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Title | Periplasmic domain of Escherichia coli CpxA |
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Components | Sensor histidine kinase CpxA |
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Keywords | SIGNALING PROTEIN / PAS domain / sensor / inner membrane |
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Function / homology | Function and homology information
cell adhesion involved in biofilm formation / cellular response to cell envelope stress / histidine kinase / phosphoprotein phosphatase activity / phosphorelay sensor kinase activity / response to radiation / signal transduction / ATP binding / identical protein binding / plasma membraneSimilarity search - Function Two-component sensor protein CpxA, periplasmic domain / Two-component sensor protein CpxA, periplasmic domain superfamily / Two-component sensor protein CpxA, periplasmic domain / HAMP domain / HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain / HAMP domain profile. / HAMP domain / His Kinase A (phospho-acceptor) domain / His Kinase A (phosphoacceptor) domain / Signal transduction histidine kinase, dimerisation/phosphoacceptor domain ...Two-component sensor protein CpxA, periplasmic domain / Two-component sensor protein CpxA, periplasmic domain superfamily / Two-component sensor protein CpxA, periplasmic domain / HAMP domain / HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain / HAMP domain profile. / HAMP domain / His Kinase A (phospho-acceptor) domain / His Kinase A (phosphoacceptor) domain / Signal transduction histidine kinase, dimerisation/phosphoacceptor domain / Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily / Signal transduction histidine kinase-related protein, C-terminal / Histidine kinase domain / Histidine kinase domain profile. / Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase / Histidine kinase-like ATPases / Histidine kinase/HSP90-like ATPase / Histidine kinase/HSP90-like ATPase superfamilySimilarity search - Domain/homology |
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Biological species | ![](img/tx_bacteria.gif) Escherichia coli K-12 (bacteria) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.8 Å |
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Authors | Glover, M.J.N. / Murray, C.R.A. / Edwards, R.A. / Thede, G.L. |
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Funding support | Canada, 4items Organization | Grant number | Country |
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Natural Sciences and Engineering Research Council (NSERC, Canada) | RGPIN-2021-02710 | Canada | Natural Sciences and Engineering Research Council (NSERC, Canada) | RGPIN-2016-05163 | Canada | Canadian Institutes of Health Research (CIHR) | CIHR168972 | Canada | Canadian Institutes of Health Research (CIHR) | CIHR142347 | Canada |
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Citation | Journal: J.Biol.Chem. / Year: 2024 Title: The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim domains. Authors: Cho, T.H.S. / Murray, C. / Malpica, R. / Margain-Quevedo, R. / Thede, G.L. / Lu, J. / Edwards, R.A. / Glover, J.N.M. / Raivio, T.L. |
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History | Deposition | Oct 12, 2023 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Oct 25, 2023 | Provider: repository / Type: Initial release |
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Revision 1.1 | Apr 17, 2024 | Group: Database references / Category: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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Revision 1.2 | May 15, 2024 | Group: Database references / Category: citation / Item: _citation.journal_volume / _citation.title |
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