登録情報 データベース : PDB / ID : 8th7 構造の表示 ダウンロードとリンクタイトル Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide 要素Caprin-1 Ras GTPase-activating protein-binding protein 1 詳細キーワード PEPTIDE BINDING PROTEIN / NTF2L Caprin1機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA / DNA/RNA helicase activity / positive regulation of stress granule assembly / intracellular mRNA localization / positive regulation of dendritic spine morphogenesis / non-membrane-bounded organelle assembly / positive regulation of dendrite morphogenesis / intracellular non-membrane-bounded organelle / generation of neurons / cell leading edge ... regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA / DNA/RNA helicase activity / positive regulation of stress granule assembly / intracellular mRNA localization / positive regulation of dendritic spine morphogenesis / non-membrane-bounded organelle assembly / positive regulation of dendrite morphogenesis / intracellular non-membrane-bounded organelle / generation of neurons / cell leading edge / ribosomal small subunit binding / positive regulation of type I interferon production / signaling adaptor activity / stress granule assembly / DNA helicase activity / synapse assembly / molecular condensate scaffold activity / molecular function activator activity / P-body / negative regulation of canonical Wnt signaling pathway / cytoplasmic stress granule / lamellipodium / perikaryon / endonuclease activity / defense response to virus / DNA helicase / Ras protein signal transduction / RNA helicase activity / negative regulation of translation / RNA helicase / ribonucleoprotein complex / innate immune response / focal adhesion / mRNA binding / synapse / dendrite / SARS-CoV-2 activates/modulates innate and adaptive immune responses / ATP hydrolysis activity / DNA binding / RNA binding / ATP binding / membrane / nucleus / cytoplasm / cytosol 類似検索 - 分子機能 Cytoplasmic activation/proliferation-associated protein-1 C term / Cytoplasmic activation/proliferation-associated protein-1 C term / Caprin / Caprin-1 dimerization domain / Caprin-1 dimerization domain / G3BP1, RNA recognition motif / Ras GTPase-activating protein-binding protein / Nuclear transport factor 2, eukaryote / Nuclear transport factor 2 domain profile. / Nuclear transport factor 2 domain ... Cytoplasmic activation/proliferation-associated protein-1 C term / Cytoplasmic activation/proliferation-associated protein-1 C term / Caprin / Caprin-1 dimerization domain / Caprin-1 dimerization domain / G3BP1, RNA recognition motif / Ras GTPase-activating protein-binding protein / Nuclear transport factor 2, eukaryote / Nuclear transport factor 2 domain profile. / Nuclear transport factor 2 domain / Nuclear transport factor 2 (NTF2) domain / NTF2-like domain superfamily / RNA recognition motif / RNA recognition motif / Eukaryotic RNA Recognition Motif (RRM) profile. / RNA recognition motif domain / RNA-binding domain superfamily / Nucleotide-binding alpha-beta plait domain superfamily 類似検索 - ドメイン・相同性 Ras GTPase-activating protein-binding protein 1 / Caprin-1 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.88 Å 詳細データ登録者 Hughes, M.P. / Taylor, J.P. / Yang, Z. 資金援助 米国, 1件 詳細 詳細を隠す組織 認可番号 国 Howard Hughes Medical Institute (HHMI) R35NS097974 米国
引用ジャーナル : Cell Rep / 年 : 2024タイトル : Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.著者: Yang, Z. / Johnson, B.A. / Meliopoulos, V.A. / Ju, X. / Zhang, P. / Hughes, M.P. / Wu, J. / Koreski, K.P. / Clary, J.E. / Chang, T.C. / Wu, G. / Hixon, J. / Duffner, J. / Wong, K. / Lemieux, ... 著者 : Yang, Z. / Johnson, B.A. / Meliopoulos, V.A. / Ju, X. / Zhang, P. / Hughes, M.P. / Wu, J. / Koreski, K.P. / Clary, J.E. / Chang, T.C. / Wu, G. / Hixon, J. / Duffner, J. / Wong, K. / Lemieux, R. / Lokugamage, K.G. / Alvarado, R.E. / Crocquet-Valdes, P.A. / Walker, D.H. / Plante, K.S. / Plante, J.A. / Weaver, S.C. / Kim, H.J. / Meyers, R. / Schultz-Cherry, S. / Ding, Q. / Menachery, V.D. / Taylor, J.P. 履歴 登録 2023年7月14日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2024年3月20日 Provider : repository / タイプ : Initial release改定 1.1 2024年4月10日 Group : Database references / カテゴリ : citation / citation_authorItem : _citation.journal_abbrev / _citation.journal_id_ISSN ... _citation.journal_abbrev / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year 改定 1.2 2024年5月8日 Group : Structure summary / カテゴリ : audit_author
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