Entry Database : PDB / ID : 8shb Structure visualization Downloads & linksTitle Crystal Structure of PRMT3 with Compound YD1-208 ComponentsProtein arginine N-methyltransferase 3 Details Keywords TRANSFERASE/INHIBITOR / PRMT3 / YD1-208 / Structural Genomics / PSI-2 / Protein Structure Initiative / Structural Genomics Consortium / SGC / TRANSFERASE / TRANSFERASE-INHIBITOR complexFunction / homology Function and homology informationFunction Domain/homology Component
protein-arginine omega-N monomethyltransferase activity / negative regulation of retinoic acid biosynthetic process / type I protein arginine methyltransferase / protein-arginine omega-N asymmetric methyltransferase activity / protein-arginine N-methyltransferase activity / Protein methylation / negative regulation of protein ubiquitination / methyltransferase activity / RMTs methylate histone arginines / ribosome binding ... protein-arginine omega-N monomethyltransferase activity / negative regulation of retinoic acid biosynthetic process / type I protein arginine methyltransferase / protein-arginine omega-N asymmetric methyltransferase activity / protein-arginine N-methyltransferase activity / Protein methylation / negative regulation of protein ubiquitination / methyltransferase activity / RMTs methylate histone arginines / ribosome binding / methylation / nucleus / metal ion binding / cytoplasm / cytosol Similarity search - Function : / : / Protein arginine N-methyltransferase 3, C2H2 zinc finger domain / Protein arginine N-methyltransferase 3, C2H2 zinc finger / Ribosomal protein L11 methyltransferase (PrmA) / Protein arginine N-methyltransferase / SAM-dependent methyltransferase PRMT-type domain profile. / Zinc finger C2H2 superfamily / Zinc finger C2H2 type domain signature. / Zinc finger C2H2-type / S-adenosyl-L-methionine-dependent methyltransferase superfamily Similarity search - Domain/homologyBiological species Homo sapiens (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.09 Å DetailsAuthors Song, X. / Dong, A. / Deng, Y. / Huang, R. / Arrowsmith, C.H. / Edwards, A.M. / Min, J. / Structural Genomics Consortium (SGC) Funding support Canada, 1items Details Hide detailsOrganization Grant number Country Other private Canada
CitationJournal : To be published Title : Crystal Structure of PRMT3 with Compound YD1-208Authors : Song, X. / Dong, A. / Deng, Y. / Huang, R. / Arrowsmith, C.H. / Edwards, A.M. / Min, J. / Structural Genomics Consortium (SGC) History Deposition Apr 13, 2023 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Apr 24, 2024 Provider : repository / Type : Initial release