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Open data
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Basic information
Entry | Database: PDB / ID: 8rm3 | ||||||
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Title | Crystal structure of ferrioxamine transporter FoxA | ||||||
![]() | Ferrioxamine receptor FoxA | ||||||
![]() | MEMBRANE PROTEIN / TonB-dependent transporter Siderophore | ||||||
Function / homology | ![]() siderophore-iron import into cell / siderophore transport / siderophore uptake transmembrane transporter activity / outer membrane / cell outer membrane / signaling receptor activity / cell surface receptor signaling pathway Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Josts, I. / Tidow, H. / Mislin, G. | ||||||
Funding support | ![]()
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![]() | ![]() Title: Crystal structure of ferrioxamine transporter FoxA Authors: Josts, I. / Tidow, H. / Gaetan, M. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 302.3 KB | Display | ![]() |
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PDB format | ![]() | Display | ![]() | |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 2.1 MB | Display | ![]() |
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Full document | ![]() | 2.1 MB | Display | |
Data in XML | ![]() | 33.7 KB | Display | |
Data in CIF | ![]() | 44.2 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data | Similarity search - Function & homology ![]() |
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Links
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Assembly
Deposited unit | ![]()
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1 |
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Unit cell |
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Components
-Protein / Sugars , 2 types, 5 molecules A

#1: Protein | Mass: 90058.281 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() |
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#2: Sugar | ChemComp-BOG / |
-Non-polymers , 8 types, 151 molecules 












#3: Chemical | #4: Chemical | #5: Chemical | ChemComp-DMS / | #6: Chemical | #7: Chemical | #8: Chemical | ChemComp-NA / | #9: Chemical | ChemComp-A1H1T / [ | Mass: 826.740 Da / Num. of mol.: 1 / Source method: obtained synthetically / Formula: C37H56FeN9O9 / Feature type: SUBJECT OF INVESTIGATION #10: Water | ChemComp-HOH / | |
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-Details
Has ligand of interest | Y |
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Has protein modification | Y |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.52 Å3/Da / Density % sol: 51.25 % |
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Crystal grow | Temperature: 293 K / Method: vapor diffusion, sitting drop Details: 2.1 M Ammonium sulphate 0.1 M HEPES pH 7.5 0.7% n-octyl-beta-d-glucoside |
-Data collection
Diffraction | Mean temperature: 100 K / Serial crystal experiment: N |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: DECTRIS EIGER X 16M / Detector: PIXEL / Date: Aug 18, 2023 |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 0.976 Å / Relative weight: 1 |
Reflection | Resolution: 2.22→81.43 Å / Num. obs: 37981 / % possible obs: 94.8 % / Redundancy: 94.8 % / CC1/2: 0.998 / Rmerge(I) obs: 0.107 / Rpim(I) all: 0.028 / Rrim(I) all: 0.11 / Net I/σ(I): 16.1 |
Reflection shell | Resolution: 2.221→2.387 Å / Rmerge(I) obs: 1.964 / Mean I/σ(I) obs: 14.4 / Num. unique obs: 1900 / CC1/2: 0.525 / Rpim(I) all: 0.539 / Rrim(I) all: 2.038 / % possible all: 59.2 |
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Processing
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Refinement | Method to determine structure: ![]()
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Solvent computation | Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.2 Å / Solvent model: MASK | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | Biso mean: 55.98 Å2
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Refinement step | Cycle: 1 / Resolution: 2.22→81.43 Å
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