登録情報 | データベース: PDB / ID: 8qxw |
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タイトル | HCMV DNA polymerase processivity factor UL44 unphosphorylated NLS 410-433 bound to mouse importin alpha 2 |
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要素 | - DNA polymerase processivity factor
- Importin subunit alpha-1
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キーワード | TRANSPORT PROTEIN / importin / karyopherin / nuclear / nls |
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機能・相同性 | 機能・相同性情報
Sensing of DNA Double Strand Breaks / entry of viral genome into host nucleus through nuclear pore complex via importin / positive regulation of viral life cycle / bidirectional double-stranded viral DNA replication / NLS-dependent protein nuclear import complex / postsynapse to nucleus signaling pathway / nuclear import signal receptor activity / nuclear localization sequence binding / NLS-bearing protein import into nucleus / DNA polymerase processivity factor activity ...Sensing of DNA Double Strand Breaks / entry of viral genome into host nucleus through nuclear pore complex via importin / positive regulation of viral life cycle / bidirectional double-stranded viral DNA replication / NLS-dependent protein nuclear import complex / postsynapse to nucleus signaling pathway / nuclear import signal receptor activity / nuclear localization sequence binding / NLS-bearing protein import into nucleus / DNA polymerase processivity factor activity / virion component / cytoplasmic stress granule / protein import into nucleus / host cell / symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity / DNA-binding transcription factor binding / DNA replication / postsynaptic density / virus-mediated perturbation of host defense response / glutamatergic synapse / host cell nucleus / DNA binding / nucleoplasm / nucleus / cytosol類似検索 - 分子機能 Herpesvirus polymerase accessory protein / Herpesvirus polymerase accessory protein / Importin subunit alpha / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain superfamily / Importin beta binding domain / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain / IBB domain profile. / Armadillo/plakoglobin ARM repeat profile. ...Herpesvirus polymerase accessory protein / Herpesvirus polymerase accessory protein / Importin subunit alpha / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain superfamily / Importin beta binding domain / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain / IBB domain profile. / Armadillo/plakoglobin ARM repeat profile. / Armadillo/beta-catenin-like repeat / : / Armadillo/beta-catenin-like repeats / Armadillo / Armadillo-like helical / Armadillo-type fold類似検索 - ドメイン・相同性 DNA polymerase processivity factor / Importin subunit alpha-1類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) Mus musculus (ハツカネズミ)
![](img/tx_virus.gif) Human betaherpesvirus 5 (ヘルペスウイルス) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2 Å |
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データ登録者 | Cross, E.M. / Marin, O. / Ariawan, D. / Aragao, D. / Cozza, G. / Di Iorio, E. / Forwood, J.K. / Alvisi, G. |
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資金援助 | 1件 |
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引用 | ジャーナル: Febs Lett. / 年: 2024 タイトル: Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44. 著者: Cross, E.M. / Marin, O. / Ariawan, D. / Aragao, D. / Cozza, G. / Di Iorio, E. / Forwood, J.K. / Alvisi, G. |
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履歴 | 登録 | 2023年10月25日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2023年11月8日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2024年1月17日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _citation_author.identifier_ORCID / _citation_author.name |
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改定 1.2 | 2024年2月7日 | Group: Database references / カテゴリ: citation Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.year |
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