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- PDB-8p4v: 80S yeast ribosome in complex with HaterumaimideQ -

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基本情報

登録情報
データベース: PDB / ID: 8p4v
タイトル80S yeast ribosome in complex with HaterumaimideQ
要素
  • (40S ribosomal protein ...) x 28
  • (60S ribosomal protein ...) x 39
  • (Small ribosomal subunit protein ...) x 4
  • 18S ribosomal RNA
  • 25S ribosomal RNA
  • 5.8S ribosomal RNA
  • 5S ribosomal RNA
  • 60S acidic protein P0
  • Guanine nucleotide-binding protein subunit beta-like protein
  • Large ribosomal subunit protein uL5B
  • Suppressor protein STM1
  • Ubiquitin
  • Ubiquitin-60S ribosomal protein L40
キーワードRIBOSOME / E-site / eL42
機能・相同性
機能・相同性情報


triplex DNA binding / ribosome hibernation / translation elongation factor binding / Platelet degranulation / regulation of translational initiation in response to stress / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) / Negative regulators of DDX58/IFIH1 signaling / regulation of amino acid metabolic process / negative regulation of glucose mediated signaling pathway / positive regulation of translational fidelity ...triplex DNA binding / ribosome hibernation / translation elongation factor binding / Platelet degranulation / regulation of translational initiation in response to stress / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) / Negative regulators of DDX58/IFIH1 signaling / regulation of amino acid metabolic process / negative regulation of glucose mediated signaling pathway / positive regulation of translational fidelity / RMTs methylate histone arginines / Protein methylation / mTORC1-mediated signalling / Protein hydroxylation / ribosome-associated ubiquitin-dependent protein catabolic process / GDP-dissociation inhibitor activity / positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay / pre-mRNA 5'-splice site binding / Formation of the ternary complex, and subsequently, the 43S complex / Translation initiation complex formation / Ribosomal scanning and start codon recognition / preribosome, small subunit precursor / nonfunctional rRNA decay / response to cycloheximide / cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / telomeric DNA binding / Major pathway of rRNA processing in the nucleolus and cytosol / mRNA destabilization / SRP-dependent cotranslational protein targeting to membrane / GTP hydrolysis and joining of the 60S ribosomal subunit / negative regulation of translational frameshifting / TOR signaling / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / negative regulation of mRNA splicing, via spliceosome / Formation of a pool of free 40S subunits / preribosome, large subunit precursor / positive regulation of protein kinase activity / L13a-mediated translational silencing of Ceruloplasmin expression / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / ribosomal large subunit export from nucleus / translational elongation / G-protein alpha-subunit binding / 90S preribosome / Ub-specific processing proteases / ribosomal subunit export from nucleus / regulation of translational fidelity / protein-RNA complex assembly / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / translational termination / maturation of LSU-rRNA / ribosomal small subunit export from nucleus / translation regulator activity / translation repressor activity / DNA-(apurinic or apyrimidinic site) endonuclease activity / rescue of stalled ribosome / telomere maintenance / cellular response to amino acid starvation / protein kinase C binding / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / ribosomal large subunit biogenesis / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / ribosome assembly / maturation of SSU-rRNA / small-subunit processome / translational initiation / macroautophagy / maintenance of translational fidelity / modification-dependent protein catabolic process / protein tag activity / cytoplasmic stress granule / rRNA processing / ribosome biogenesis / ribosome binding / ribosomal small subunit biogenesis / ribosomal small subunit assembly / small ribosomal subunit / 5S rRNA binding / small ribosomal subunit rRNA binding / ribosomal large subunit assembly / cytosolic small ribosomal subunit / large ribosomal subunit rRNA binding / cytosolic large ribosomal subunit / cytoplasmic translation / negative regulation of translation / rRNA binding / protein ubiquitination / structural constituent of ribosome / ribosome / translation / G protein-coupled receptor signaling pathway / negative regulation of gene expression / response to antibiotic / mRNA binding / ubiquitin protein ligase binding / negative regulation of apoptotic process / nucleolus / perinuclear region of cytoplasm / mitochondrion / DNA binding
類似検索 - 分子機能
Stm1-like, N-terminal / Stm1 / Hyaluronan/mRNA-binding protein / Hyaluronan / mRNA binding family / : / : / Ribosomal protein S26e signature. / Ribosomal protein L41 / Ribosomal protein L41 / Ribosomal protein S21e, conserved site ...Stm1-like, N-terminal / Stm1 / Hyaluronan/mRNA-binding protein / Hyaluronan / mRNA binding family / : / : / Ribosomal protein S26e signature. / Ribosomal protein L41 / Ribosomal protein L41 / Ribosomal protein S21e, conserved site / Ribosomal protein S21e signature. / : / Ribosomal protein S12e signature. / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein S12e / Ribosomal protein L13e, conserved site / Ribosomal protein L13e signature. / Ribosomal protein L29e / Ribosomal L29e protein family / Ribosomal protein S19e, conserved site / Ribosomal protein S19e signature. / Ribosomal protein S5, eukaryotic/archaeal / Small (40S) ribosomal subunit Asc1/RACK1 / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein S2, eukaryotic / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / S27a-like superfamily / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / 40S Ribosomal protein S10 / : / Ribosomal protein S7e signature. / Ribosomal protein L19, eukaryotic / Ribosomal protein L10e / Ribosomal protein L24e, conserved site / : / Ribosomal protein L24e signature. / Ribosomal protein L44e signature. / Ribosomal protein L19/L19e conserved site / Ribosomal protein L19e signature. / Ribosomal protein L6e signature. / Ribosomal protein L13e / Ribosomal protein L13e / Plectin/S10, N-terminal / Plectin/S10 domain / 60S ribosomal protein L18a/ L20, eukaryotes / Ribosomal protein S8e subdomain, eukaryotes / Ribosomal protein S10, eukaryotic/archaeal / Ribosomal protein S30 / Ribosomal protein S17e, conserved site / Ribosomal protein S30 / Ribosomal protein S17e signature. / Ribosomal protein L34e, conserved site / Ribosomal protein L34e signature. / Ribosomal protein S3Ae, conserved site / Ribosomal protein S3Ae signature. / Ribosomal protein S25 / S25 ribosomal protein / Ribosomal protein S27a / Ribosomal protein S27a / Ribosomal protein S27a / : / Ribosomal protein S2, eukaryotic/archaeal / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein L44e / Ribosomal protein L44 / Ribosomal protein L23/L25, N-terminal / Ribosomal protein L23, N-terminal domain / Ribosomal protein L18/L18-A/B/e, conserved site / Ribosomal protein L18e signature. / 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a / Ribosomal protein L30e signature 1. / Ribosomal L40e family / Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A / Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A / Ribosomal protein 60S L18 and 50S L18e / 40S ribosomal protein S29/30S ribosomal protein S14 type Z / Ribosomal protein L36e signature. / Ribosomal protein L35Ae, conserved site / : / Ribosomal protein L35Ae signature. / Ribosomal_L40e / Ribosomal protein L40e / Ribosomal protein L40e superfamily / Ribosomal protein S27e signature. / Ribosomal protein S3, eukaryotic/archaeal / Ribosomal protein S4e, N-terminal, conserved site / Ribosomal protein S4e signature.
類似検索 - ドメイン・相同性
: / osmium (III) hexammine / OSMIUM ION / SPERMIDINE / : / : / : / : / : / RNA ...: / osmium (III) hexammine / OSMIUM ION / SPERMIDINE / : / : / : / : / : / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Small ribosomal subunit protein uS4A / Large ribosomal subunit protein uL15 / Small ribosomal subunit protein eS17A / Large ribosomal subunit protein eL24A / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein uL30A / Large ribosomal subunit protein uL6A / Large ribosomal subunit protein uL22A / Large ribosomal subunit protein uL24A / Large ribosomal subunit protein eL33A / Large ribosomal subunit protein eL36A / Large ribosomal subunit protein eL29 / Large ribosomal subunit protein eL15A / Large ribosomal subunit protein eL22A / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS15 / Ubiquitin-ribosomal protein eS31 fusion protein / Small ribosomal subunit protein eS19A / Small ribosomal subunit protein eS21A / Small ribosomal subunit protein uS8A / Large ribosomal subunit protein eL27A / Large ribosomal subunit protein eL31A / Ubiquitin-ribosomal protein eL40A fusion protein / Large ribosomal subunit protein eL20A / Large ribosomal subunit protein eL43A / Large ribosomal subunit protein eL42A / Small ribosomal subunit protein uS12A / Small ribosomal subunit protein eS24A / Small ribosomal subunit protein eS30A / Small ribosomal subunit protein eS4A / Small ribosomal subunit protein eS6A / Small ribosomal subunit protein eS8A / Large ribosomal subunit protein uL14A / Large ribosomal subunit protein uL2A / Small ribosomal subunit protein uS17A / Large ribosomal subunit protein eL18A / Small ribosomal subunit protein uS9A / Small ribosomal subunit protein uS13A / Large ribosomal subunit protein eL19A / Large ribosomal subunit protein uL29A / Small ribosomal subunit protein eS32A / Large ribosomal subunit protein uL4A / Large ribosomal subunit protein eL30 / Large ribosomal subunit protein uL3 / Small ribosomal subunit protein eS17B / Large ribosomal subunit protein eL8A / Small ribosomal subunit protein uS5 / Large ribosomal subunit protein uL18 / Small ribosomal subunit protein uS7 / Large ribosomal subunit protein uL13A / Small ribosomal subunit protein eS7A / Small ribosomal subunit protein uS2A / Small ribosomal subunit protein eS1A / Small ribosomal subunit protein eS27A / Large ribosomal subunit protein eL14A / Small ribosomal subunit protein RACK1 / Large ribosomal subunit protein eL32 / Small ribosomal subunit protein uS10 / Suppressor protein STM1 / Small ribosomal subunit protein uS11B / Small ribosomal subunit protein eS26B / Small ribosomal subunit protein uS14A / Large ribosomal subunit protein uL16 / Small ribosomal subunit protein eS12 / Large ribosomal subunit protein eL37A / Large ribosomal subunit protein eL38 / Large ribosomal subunit protein eL34A / Small ribosomal subunit protein uS19 / Large ribosomal subunit protein eL6A / Large ribosomal subunit protein eL21A / Small ribosomal subunit protein eS10A / Large ribosomal subunit protein eL13A / Large ribosomal subunit protein uL5B / Small ribosomal subunit protein eS25A / Small ribosomal subunit protein eS28A
類似検索 - 構成要素
生物種Saccharomyces cerevisiae (パン酵母)
手法X線回折 / シンクロトロン / 分子置換 / 解像度: 3.16 Å
データ登録者Terrosu, S. / Yusupov, M.
資金援助 米国, 1件
組織認可番号国
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)GM129264 米国
引用ジャーナル: Acs Chem.Biol. / 年: 2025
タイトル: Synthesis of Differentially Halogenated Lissoclimide Analogues To Probe Ribosome E-Site Binding.
著者: Terrosu, S. / Nurullina, L. / Supantanapong, N. / Pak, B.S. / Nguyen, S. / Holm, M. / Wu, C. / Lin, M. / Horne, D. / Sachs, M.S. / Blanchard, S.C. / Yusupov, M. / Vanderwal, C.D.
履歴
登録2023年5月23日登録サイト: PDBE / 処理サイト: PDBE
改定 1.02024年10月16日Provider: repository / タイプ: Initial release
改定 1.12025年4月30日Group: Database references / カテゴリ: citation / citation_author
Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year

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構造の表示

構造ビューア分子:
MolmilJmol/JSmol

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集合体

登録構造単位
1: 25S ribosomal RNA
3: 5S ribosomal RNA
4: 5.8S ribosomal RNA
j: 60S ribosomal protein L2-A
k: 60S ribosomal protein L3
l: 60S ribosomal protein L4-A
m: 60S ribosomal protein L5
n: 60S ribosomal protein L6-A
o: 60S ribosomal protein L7-A
p: 60S ribosomal protein L8-A
q: 60S ribosomal protein L9-A
r: 60S ribosomal protein L10
s: Large ribosomal subunit protein uL5B
t: 60S ribosomal protein L13-A
u: 60S ribosomal protein L14-A
v: 60S ribosomal protein L15-A
w: 60S ribosomal protein L16-A
x: 60S ribosomal protein L17-A
y: 60S ribosomal protein L18-A
z: 60S ribosomal protein L19-A
0: 60S ribosomal protein L20-A
2: 60S ribosomal protein L21-A
5: 60S ribosomal protein L22-A
6: 60S ribosomal protein L23-A
7: 60S ribosomal protein L24-A
8: 60S ribosomal protein L25
9: 60S ribosomal protein L26-A
AA: 60S ribosomal protein L27-A
AB: 60S ribosomal protein L28
AC: 60S ribosomal protein L29
AD: 60S ribosomal protein L30
AE: 60S ribosomal protein L31-A
AF: 60S ribosomal protein L32
AG: 60S ribosomal protein L33-A
AH: 60S ribosomal protein L34-A
AI: 60S ribosomal protein L35-A
AJ: 60S ribosomal protein L36-A
AK: 60S ribosomal protein L37-A
AL: 60S ribosomal protein L38
AM: 60S ribosomal protein L39
AN: Ubiquitin-60S ribosomal protein L40
AO: 60S ribosomal protein L41-A
AP: 60S ribosomal protein L42-A
AQ: 60S ribosomal protein L43-A
i: Suppressor protein STM1
AR: 25S ribosomal RNA
AS: 5S ribosomal RNA
AT: 5.8S ribosomal RNA
CD: 60S ribosomal protein L2-A
CE: 60S ribosomal protein L3
CF: 60S ribosomal protein L4-A
CG: 60S ribosomal protein L5
CH: 60S ribosomal protein L6-A
CI: 60S ribosomal protein L7-A
CJ: 60S ribosomal protein L8-A
CK: 60S ribosomal protein L9-A
CL: 60S ribosomal protein L10
CM: Large ribosomal subunit protein uL5B
CN: 60S ribosomal protein L13-A
CO: 60S ribosomal protein L14-A
CP: 60S ribosomal protein L15-A
CQ: 60S ribosomal protein L16-A
CR: 60S ribosomal protein L17-A
CS: 60S ribosomal protein L18-A
CT: 60S ribosomal protein L19-A
CU: 60S ribosomal protein L20-A
CV: 60S ribosomal protein L21-A
CW: 60S ribosomal protein L22-A
CX: 60S ribosomal protein L23-A
CY: 60S ribosomal protein L24-A
CZ: 60S ribosomal protein L25
DA: 60S ribosomal protein L26-A
DB: 60S ribosomal protein L27-A
DC: 60S ribosomal protein L28
DD: 60S ribosomal protein L29
DE: 60S ribosomal protein L30
DF: 60S ribosomal protein L31-A
DG: 60S ribosomal protein L32
DH: 60S ribosomal protein L33-A
DI: 60S ribosomal protein L34-A
DJ: 60S ribosomal protein L35-A
DK: 60S ribosomal protein L36-A
DL: 60S ribosomal protein L37-A
DM: 60S ribosomal protein L38
DN: 60S ribosomal protein L39
DO: Ubiquitin-60S ribosomal protein L40
DP: 60S ribosomal protein L41-A
DQ: 60S ribosomal protein L42-A
DR: 60S ribosomal protein L43-A
p0: 60S acidic protein P0
sM: Suppressor protein STM1
A: 18S ribosomal RNA
B: 40S ribosomal protein S0-A
C: 40S ribosomal protein S1-A
D: 40S ribosomal protein S2
E: Small ribosomal subunit protein uS3
F: 40S ribosomal protein S4-A
G: 40S ribosomal protein S5
H: 40S ribosomal protein S6-A
I: 40S ribosomal protein S7-A
J: 40S ribosomal protein S8-A
K: 40S ribosomal protein S9-A
L: 40S ribosomal protein S10-A
M: 40S ribosomal protein S11-A
N: 40S ribosomal protein S12
O: 40S ribosomal protein S13
P: 40S ribosomal protein S14-B
Q: 40S ribosomal protein S15
R: 40S ribosomal protein S16-A
S: 40S ribosomal protein S17-B
T: 40S ribosomal protein S18-A
U: 40S ribosomal protein S19-A
V: Small ribosomal subunit protein uS10
W: 40S ribosomal protein S21-A
X: 40S ribosomal protein S22-A
Y: 40S ribosomal protein S23-A
Z: 40S ribosomal protein S24-A
a: 40S ribosomal protein S25-A
b: Small ribosomal subunit protein eS26B
c: 40S ribosomal protein S27-A
d: 40S ribosomal protein S28-A
e: Small ribosomal subunit protein uS14A
f: 40S ribosomal protein S30-A
g: Ubiquitin
h: Guanine nucleotide-binding protein subunit beta-like protein
sR: 18S ribosomal RNA
Rb: Guanine nucleotide-binding protein subunit beta-like protein
s0: 40S ribosomal protein S0-A
s1: 40S ribosomal protein S1-A
s2: 40S ribosomal protein S2
s3: Small ribosomal subunit protein uS3
s4: 40S ribosomal protein S4-A
s5: 40S ribosomal protein S5
s6: 40S ribosomal protein S6-A
s7: 40S ribosomal protein S7-A
s8: 40S ribosomal protein S8-A
s9: 40S ribosomal protein S9-A
c0: 40S ribosomal protein S10-A
c1: 40S ribosomal protein S11-A
c2: 40S ribosomal protein S12
c3: 40S ribosomal protein S13
c4: 40S ribosomal protein S14-B
c5: 40S ribosomal protein S15
c6: 40S ribosomal protein S16-A
c7: 40S ribosomal protein S17-A
c8: 40S ribosomal protein S18-A
c9: 40S ribosomal protein S19-A
d0: Small ribosomal subunit protein uS10
d1: 40S ribosomal protein S21-A
d2: 40S ribosomal protein S22-A
d3: 40S ribosomal protein S23-A
d4: 40S ribosomal protein S24-A
d5: 40S ribosomal protein S25-A
d6: Small ribosomal subunit protein eS26B
d7: 40S ribosomal protein S27-A
d8: 40S ribosomal protein S28-A
d9: Small ribosomal subunit protein uS14A
e0: 40S ribosomal protein S30-A
e1: Ubiquitin
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)6,616,4292616
ポリマ－6,305,190159
非ポリマー311,2392457
水9,062503
1
1: 25S ribosomal RNA
3: 5S ribosomal RNA
4: 5.8S ribosomal RNA
j: 60S ribosomal protein L2-A
k: 60S ribosomal protein L3
l: 60S ribosomal protein L4-A
m: 60S ribosomal protein L5
n: 60S ribosomal protein L6-A
o: 60S ribosomal protein L7-A
p: 60S ribosomal protein L8-A
q: 60S ribosomal protein L9-A
r: 60S ribosomal protein L10
s: Large ribosomal subunit protein uL5B
t: 60S ribosomal protein L13-A
u: 60S ribosomal protein L14-A
v: 60S ribosomal protein L15-A
w: 60S ribosomal protein L16-A
x: 60S ribosomal protein L17-A
y: 60S ribosomal protein L18-A
z: 60S ribosomal protein L19-A
0: 60S ribosomal protein L20-A
2: 60S ribosomal protein L21-A
5: 60S ribosomal protein L22-A
6: 60S ribosomal protein L23-A
7: 60S ribosomal protein L24-A
8: 60S ribosomal protein L25
9: 60S ribosomal protein L26-A
AA: 60S ribosomal protein L27-A
AB: 60S ribosomal protein L28
AC: 60S ribosomal protein L29
AD: 60S ribosomal protein L30
AE: 60S ribosomal protein L31-A
AF: 60S ribosomal protein L32
AG: 60S ribosomal protein L33-A
AH: 60S ribosomal protein L34-A
AI: 60S ribosomal protein L35-A
AJ: 60S ribosomal protein L36-A
AK: 60S ribosomal protein L37-A
AL: 60S ribosomal protein L38
AM: 60S ribosomal protein L39
AN: Ubiquitin-60S ribosomal protein L40
AO: 60S ribosomal protein L41-A
AP: 60S ribosomal protein L42-A
AQ: 60S ribosomal protein L43-A
i: Suppressor protein STM1
A: 18S ribosomal RNA
B: 40S ribosomal protein S0-A
C: 40S ribosomal protein S1-A
D: 40S ribosomal protein S2
E: Small ribosomal subunit protein uS3
F: 40S ribosomal protein S4-A
G: 40S ribosomal protein S5
H: 40S ribosomal protein S6-A
I: 40S ribosomal protein S7-A
J: 40S ribosomal protein S8-A
K: 40S ribosomal protein S9-A
L: 40S ribosomal protein S10-A
M: 40S ribosomal protein S11-A
N: 40S ribosomal protein S12
O: 40S ribosomal protein S13
P: 40S ribosomal protein S14-B
Q: 40S ribosomal protein S15
R: 40S ribosomal protein S16-A
S: 40S ribosomal protein S17-B
T: 40S ribosomal protein S18-A
U: 40S ribosomal protein S19-A
V: Small ribosomal subunit protein uS10
W: 40S ribosomal protein S21-A
X: 40S ribosomal protein S22-A
Y: 40S ribosomal protein S23-A
Z: 40S ribosomal protein S24-A
a: 40S ribosomal protein S25-A
b: Small ribosomal subunit protein eS26B
c: 40S ribosomal protein S27-A
d: 40S ribosomal protein S28-A
e: Small ribosomal subunit protein uS14A
f: 40S ribosomal protein S30-A
g: Ubiquitin
h: Guanine nucleotide-binding protein subunit beta-like protein
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)3,286,5751264
ポリマ－3,135,99479
非ポリマー150,5821185
水18010
タイプ名称対称操作数
identity operation1_555x,y,z1
2
AR: 25S ribosomal RNA
AS: 5S ribosomal RNA
AT: 5.8S ribosomal RNA
CD: 60S ribosomal protein L2-A
CE: 60S ribosomal protein L3
CF: 60S ribosomal protein L4-A
CG: 60S ribosomal protein L5
CH: 60S ribosomal protein L6-A
CI: 60S ribosomal protein L7-A
CJ: 60S ribosomal protein L8-A
CK: 60S ribosomal protein L9-A
CL: 60S ribosomal protein L10
CM: Large ribosomal subunit protein uL5B
CN: 60S ribosomal protein L13-A
CO: 60S ribosomal protein L14-A
CP: 60S ribosomal protein L15-A
CQ: 60S ribosomal protein L16-A
CR: 60S ribosomal protein L17-A
CS: 60S ribosomal protein L18-A
CT: 60S ribosomal protein L19-A
CU: 60S ribosomal protein L20-A
CV: 60S ribosomal protein L21-A
CW: 60S ribosomal protein L22-A
CX: 60S ribosomal protein L23-A
CY: 60S ribosomal protein L24-A
CZ: 60S ribosomal protein L25
DA: 60S ribosomal protein L26-A
DB: 60S ribosomal protein L27-A
DC: 60S ribosomal protein L28
DD: 60S ribosomal protein L29
DE: 60S ribosomal protein L30
DF: 60S ribosomal protein L31-A
DG: 60S ribosomal protein L32
DH: 60S ribosomal protein L33-A
DI: 60S ribosomal protein L34-A
DJ: 60S ribosomal protein L35-A
DK: 60S ribosomal protein L36-A
DL: 60S ribosomal protein L37-A
DM: 60S ribosomal protein L38
DN: 60S ribosomal protein L39
DO: Ubiquitin-60S ribosomal protein L40
DP: 60S ribosomal protein L41-A
DQ: 60S ribosomal protein L42-A
DR: 60S ribosomal protein L43-A
p0: 60S acidic protein P0
sM: Suppressor protein STM1
sR: 18S ribosomal RNA
Rb: Guanine nucleotide-binding protein subunit beta-like protein
s0: 40S ribosomal protein S0-A
s1: 40S ribosomal protein S1-A
s2: 40S ribosomal protein S2
s3: Small ribosomal subunit protein uS3
s4: 40S ribosomal protein S4-A
s5: 40S ribosomal protein S5
s6: 40S ribosomal protein S6-A
s7: 40S ribosomal protein S7-A
s8: 40S ribosomal protein S8-A
s9: 40S ribosomal protein S9-A
c0: 40S ribosomal protein S10-A
c1: 40S ribosomal protein S11-A
c2: 40S ribosomal protein S12
c3: 40S ribosomal protein S13
c4: 40S ribosomal protein S14-B
c5: 40S ribosomal protein S15
c6: 40S ribosomal protein S16-A
c7: 40S ribosomal protein S17-A
c8: 40S ribosomal protein S18-A
c9: 40S ribosomal protein S19-A
d0: Small ribosomal subunit protein uS10
d1: 40S ribosomal protein S21-A
d2: 40S ribosomal protein S22-A
d3: 40S ribosomal protein S23-A
d4: 40S ribosomal protein S24-A
d5: 40S ribosomal protein S25-A
d6: Small ribosomal subunit protein eS26B
d7: 40S ribosomal protein S27-A
d8: 40S ribosomal protein S28-A
d9: Small ribosomal subunit protein uS14A
e0: 40S ribosomal protein S30-A
e1: Ubiquitin
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)3,329,8531352
ポリマ－3,169,19680
非ポリマー160,6571272
水21612
タイプ名称対称操作数
identity operation1_555x,y,z1
単位格子
Length a, b, c (Å)302.580, 285.050, 433.720
Angle α, β, γ (deg.)90.000, 98.890, 90.000
Int Tables number4
Space group name H-MP1211
Space group name HallP2yb
Symmetry operation#1: x,y,z
#2: -x,y+1/2,-z

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要素

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RNA鎖 , 4種, 8分子 1AR3AS4ATAsR

#1: RNA鎖 25S ribosomal RNA


分子量: 1097493.875 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: GenBank: 834774822
#2: RNA鎖 5S ribosomal RNA


分子量: 38951.105 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: GenBank: 1329886537
#3: RNA鎖 5.8S ribosomal RNA


分子量: 50682.922 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: GenBank: 1331532632
#47: RNA鎖 18S ribosomal RNA


分子量: 579761.938 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: GenBank: 874346701

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60S ribosomal protein ... , 39種, 78分子 jCDkCElCFmCGnCHoCIpCJqCKrCLtCNuCOvCPwCQxCRyCS...

#4: タンパク質 60S ribosomal protein L2-A / L5 / Large ribosomal subunit protein uL2-A / RP8 / YL6


分子量: 27463.574 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX45
#5: タンパク質 60S ribosomal protein L3 / Large ribosomal subunit protein uL3 / Maintenance of killer protein 8 / RP1 / Trichodermin ...Large ribosomal subunit protein uL3 / Maintenance of killer protein 8 / RP1 / Trichodermin resistance protein / YL1


分子量: 43850.793 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P14126
#6: タンパク質 60S ribosomal protein L4-A / L2 / Large ribosomal subunit protein uL4-A / RP2 / YL2


分子量: 39159.125 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P10664
#7: タンパク質 60S ribosomal protein L5 / L1 / L1a / Large ribosomal subunit protein uL18 / Ribosomal 5S RNA-binding protein / YL3


分子量: 33764.828 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P26321
#8: タンパク質 60S ribosomal protein L6-A / L17 / Large ribosomal subunit protein eL6-A / RP18 / YL16


分子量: 20000.564 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q02326
#9: タンパク質 60S ribosomal protein L7-A / L6 / Large ribosomal subunit protein uL30-A / RP11 / YL8


分子量: 27686.281 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05737
#10: タンパク質 60S ribosomal protein L8-A / L4 / L4-2 / L7a-1 / Large ribosomal subunit protein eL8-A / Maintenance of killer protein 7 / RP6 / YL5


分子量: 28175.820 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P17076
#11: タンパク質 60S ribosomal protein L9-A / L8 / Large ribosomal subunit protein uL6-A / RP24 / YL11


分子量: 21605.061 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05738
#12: タンパク質 60S ribosomal protein L10 / L9 / Large ribosomal subunit protein uL16 / Ubiquinol-cytochrome C reductase complex subunit VI- ...L9 / Large ribosomal subunit protein uL16 / Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein


分子量: 25410.465 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P41805
#14: タンパク質 60S ribosomal protein L13-A / Large ribosomal subunit protein eL13-A


分子量: 22604.164 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q12690
#15: タンパク質 60S ribosomal protein L14-A / Large ribosomal subunit protein eL14-A


分子量: 15195.066 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P36105
#16: タンパク質 60S ribosomal protein L15-A / L13 / Large ribosomal subunit protein eL15-A / RP15R / YL10 / YP18


分子量: 24482.357 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05748
#17: タンパク質 60S ribosomal protein L16-A / L13a / L21 / Large ribosomal subunit protein uL13-A / RP22 / YL15


分子量: 22247.227 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P26784
#18: タンパク質 60S ribosomal protein L17-A / L20A / Large ribosomal subunit protein uL22-A / YL17


分子量: 20589.518 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05740
#19: タンパク質 60S ribosomal protein L18-A / Large ribosomal subunit protein eL18-A / RP28


分子量: 20609.252 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX49
#20: タンパク質 60S ribosomal protein L19-A / L23 / Large ribosomal subunit protein eL19-A / RP15L / RP33 / YL14


分子量: 21762.316 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX82
#21: タンパク質 60S ribosomal protein L20-A / L18a / Large ribosomal subunit protein eL20-A


分子量: 20478.852 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX23
#22: タンパク質 60S ribosomal protein L21-A / Large ribosomal subunit protein eL21-A


分子量: 18279.266 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q02753
#23: タンパク質 60S ribosomal protein L22-A / L1c / Large ribosomal subunit protein eL22-A / RP4 / YL31


分子量: 13711.359 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05749
#24: タンパク質 60S ribosomal protein L23-A / L17a / Large ribosomal subunit protein uL14-A / YL32


分子量: 14493.950 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX41
#25: タンパク質 60S ribosomal protein L24-A / L30 / Large ribosomal subunit protein eL24-A / RP29 / YL21


分子量: 17661.717 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P04449
#26: タンパク質 60S ribosomal protein L25 / Large ribosomal subunit protein uL23 / RP16L / YL25 / YP42'


分子量: 15787.612 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P04456
#27: タンパク質 60S ribosomal protein L26-A / L33 / Large ribosomal subunit protein uL24-A / YL33


分子量: 14265.784 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05743
#28: タンパク質 60S ribosomal protein L27-A / Large ribosomal subunit protein eL27-A


分子量: 15568.360 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0C2H6
#29: タンパク質 60S ribosomal protein L28 / L27a / L29 / Large ribosomal subunit protein uL15 / RP44 / RP62 / YL24


分子量: 16761.666 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P02406
#30: タンパク質 60S ribosomal protein L29 / Large ribosomal subunit protein eL29 / YL43


分子量: 6691.884 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05747
#31: タンパク質 60S ribosomal protein L30 / L32 / Large ribosomal subunit protein eL30 / RP73 / YL38


分子量: 11430.364 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P14120
#32: タンパク質 60S ribosomal protein L31-A / L34 / Large ribosomal subunit protein eL31-A / YL28


分子量: 12980.158 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0C2H8
#33: タンパク質 60S ribosomal protein L32 / Large ribosomal subunit protein eL32


分子量: 14809.441 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P38061
#34: タンパク質 60S ribosomal protein L33-A / L37 / Large ribosomal subunit protein eL33-A / RP47 / YL37


分子量: 12177.130 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05744
#35: タンパク質 60S ribosomal protein L34-A / Large ribosomal subunit protein eL34-A


分子量: 13673.196 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P87262
#36: タンパク質 60S ribosomal protein L35-A / Large ribosomal subunit protein uL29-A


分子量: 13942.640 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX84
#37: タンパク質 60S ribosomal protein L36-A / L39 / Large ribosomal subunit protein eL36-A / YL39


分子量: 11151.259 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05745
#38: タンパク質 60S ribosomal protein L37-A / L43 / Large ribosomal subunit protein eL37-A / YL35 / YP55


分子量: 9877.395 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P49166
#39: タンパク質 60S ribosomal protein L38 / Large ribosomal subunit protein eL38


分子量: 8845.561 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P49167
#40: タンパク質 60S ribosomal protein L39 / L46 / Large ribosomal subunit protein eL39 / YL40


分子量: 6358.640 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P04650
#42: タンパク質・ペプチド 60S ribosomal protein L41-A / L47 / Large ribosomal subunit protein eL41-A / YL41


分子量: 3354.243 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX86
#43: タンパク質 60S ribosomal protein L42-A / L41 / Large ribosomal subunit protein eL42-A / YL27 / YP44


分子量: 12246.658 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX27
#44: タンパク質 60S ribosomal protein L43-A / L37a / Large ribosomal subunit protein eL43-A / YL35


分子量: 10112.952 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX25

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タンパク質 , 6種, 11分子 sCMANDOisMp0ge1hRb

#13: タンパク質 Large ribosomal subunit protein uL5B / 60S ribosomal protein L11-B / L16 / RP39 / YL22


分子量: 19785.719 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q3E757
#41: タンパク質 Ubiquitin-60S ribosomal protein L40


分子量: 14583.077 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CH08
#45: タンパク質 Suppressor protein STM1 / 3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / ...3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / Ribosomal subunits association factor / AF / TOM1 suppressor protein 1 / Triplex-binding protein 1


分子量: 30048.010 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P39015
#46: タンパク質 60S acidic protein P0


分子量: 33217.262 Da / 分子数: 1 / 由来タイプ: 天然 / 詳細: PolyA remodelled because of poor density / 由来: (天然) Saccharomyces cerevisiae (パン酵母)
#79: タンパク質 Ubiquitin


分子量: 17254.227 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05759
#80: タンパク質 Guanine nucleotide-binding protein subunit beta-like protein / Receptor for activated C kinase / Receptor of activated protein kinase C 1 / RACK1 / Small ...Receptor for activated C kinase / Receptor of activated protein kinase C 1 / RACK1 / Small ribosomal subunit protein RACK1


分子量: 34841.219 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P38011

+
40S ribosomal protein ... , 28種, 54分子 Bs0Cs1Ds2Fs4Gs5Hs6Is7Js8Ks9Lc0Mc1Nc2Oc3Pc4Qc5...

#48: タンパク質 40S ribosomal protein S0-A / Nucleic acid-binding protein NAB1A / Small ribosomal subunit protein uS2-A


分子量: 28051.330 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P32905
#49: タンパク質 40S ribosomal protein S1-A / RP10A / Small ribosomal subunit protein eS1-A


分子量: 28798.467 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P33442
#50: タンパク質 40S ribosomal protein S2 / Omnipotent suppressor protein SUP44 / RP12 / S4 / Small ribosomal subunit protein uS5 / YS5


分子量: 27490.826 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P25443
#52: タンパク質 40S ribosomal protein S4-A / RP5 / S7 / Small ribosomal subunit protein eS4-A / YS6


分子量: 29469.330 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX35
#53: タンパク質 40S ribosomal protein S5 / RP14 / S2 / Small ribosomal subunit protein uS7 / YS8


分子量: 25072.600 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P26783
#54: タンパク質 40S ribosomal protein S6-A / RP9 / S10 / Small ribosomal subunit protein eS6-A / YS4


分子量: 27054.486 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX37
#55: タンパク質 40S ribosomal protein S7-A / RP30 / RP40 / Small ribosomal subunit protein eS7-A


分子量: 21658.209 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P26786
#56: タンパク質 40S ribosomal protein S8-A / RP19 / S14 / Small ribosomal subunit protein eS8-A / YS9


分子量: 22537.803 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX39
#57: タンパク質 40S ribosomal protein S9-A / RP21 / S13 / Small ribosomal subunit protein uS4-A / YP28 / YS11


分子量: 22487.893 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: O13516
#58: タンパク質 40S ribosomal protein S10-A / Small ribosomal subunit protein eS10-A


分子量: 12757.445 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q08745
#59: タンパク質 40S ribosomal protein S11-A / RP41 / S18 / Small ribosomal subunit protein uS17-A / YS12


分子量: 17785.934 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX47
#60: タンパク質 40S ribosomal protein S12 / Small ribosomal subunit protein eS12


分子量: 15488.631 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P48589
#61: タンパク質 40S ribosomal protein S13 / S27a / Small ribosomal subunit protein uS15 / YS15


分子量: 17059.945 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05756
#62: タンパク質 40S ribosomal protein S14-B / RP59B / Small ribosomal subunit protein uS11-B


分子量: 14675.771 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P39516
#63: タンパク質 40S ribosomal protein S15 / RIG protein / RP52 / S21 / Small ribosomal subunit protein uS19 / YS21


分子量: 16031.907 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q01855
#64: タンパク質 40S ribosomal protein S16-A / RP61R / Small ribosomal subunit protein uS9-A


分子量: 15877.490 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX51
#65: タンパク質 40S ribosomal protein S17-B / RP51B / Small ribosomal subunit protein eS17-B


分子量: 15835.384 Da / 分子数: 1 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P14127
#66: タンパク質 40S ribosomal protein S18-A / Small ribosomal subunit protein uS13-A


分子量: 17071.641 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX55
#67: タンパク質 40S ribosomal protein S19-A / RP55A / S16a / Small ribosomal subunit protein eS19-A / YP45 / YS16A


分子量: 15942.125 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P07280
#69: タンパク質 40S ribosomal protein S21-A / S26 / Small ribosomal subunit protein eS21-A / YS25


分子量: 9758.829 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0C0V8
#70: タンパク質 40S ribosomal protein S22-A / RP50 / S24 / Small ribosomal subunit protein uS8-A / YP58 / YS22


分子量: 14650.062 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0C0W1
#71: タンパク質 40S ribosomal protein S23-A / RP37 / S28 / Small ribosomal subunit protein uS12-A / YS14


分子量: 16073.896 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX29
#72: タンパク質 40S ribosomal protein S24-A / RP50 / Small ribosomal subunit protein eS24-A


分子量: 15362.848 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX31
#73: タンパク質 40S ribosomal protein S25-A / RP45 / S31 / Small ribosomal subunit protein eS25-A / YS23


分子量: 12067.272 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q3E792
#75: タンパク質 40S ribosomal protein S27-A / RP61 / Small ribosomal subunit protein eS27-A / YS20


分子量: 8893.391 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P35997
#76: タンパク質 40S ribosomal protein S28-A / S33 / Small ribosomal subunit protein eS28-A / YS27


分子量: 7605.847 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q3E7X9
#78: タンパク質 40S ribosomal protein S30-A / Small ribosomal subunit protein eS30-A


分子量: 7137.541 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX33
#81: タンパク質 40S ribosomal protein S17-A / RP51A / Small ribosomal subunit protein eS17-A


分子量: 15820.413 Da / 分子数: 1 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P02407

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Small ribosomal subunit protein ... , 4種, 8分子 Es3Vd0bd6ed9

#51: タンパク質 Small ribosomal subunit protein uS3 / 40S ribosomal protein S3 / RP13 / YS3


分子量: 26542.789 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05750
#68: タンパク質 Small ribosomal subunit protein uS10 / 40S ribosomal protein S20


分子量: 13929.044 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P38701
#74: タンパク質 Small ribosomal subunit protein eS26B / 40S ribosomal protein S26-B


分子量: 13480.886 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P39939
#77: タンパク質 Small ribosomal subunit protein uS14A / 40S ribosomal protein S29-A / S36 / YS29


分子量: 6675.723 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P41057

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非ポリマー , 8種, 2960分子

#82: 化合物...
ChemComp-OHX / osmium (III) hexammine / osmium(6+) hexaazanide


分子量: 286.365 Da / 分子数: 953 / 由来タイプ: 合成 / 式: H12N6Os
#83: 化合物...
ChemComp-MG / MAGNESIUM ION


分子量: 24.305 Da / 分子数: 1477 / 由来タイプ: 合成 / 式: Mg
#84: 化合物
ChemComp-K / POTASSIUM ION


分子量: 39.098 Da / 分子数: 7 / 由来タイプ: 合成 / 式: K
#85: 化合物 ChemComp-SPD / SPERMIDINE / N-(2-AMINO-PROPYL)-1,4-DIAMINOBUTANE / PA(34)


分子量: 145.246 Da / 分子数: 2 / 由来タイプ: 合成 / 式: C7H19N3
#86: 化合物 ChemComp-X1K / (3~{R})-3-[(1~{S})-2-[(1~{R},3~{S},4~{a}~{S},8~{a}~{S})-5,5,8~{a}-trimethyl-2-methylidene-3-oxidanyl-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione


分子量: 349.464 Da / 分子数: 2 / 由来タイプ: 合成 / 式: C20H31NO4
#87: 化合物
ChemComp-ZN / ZINC ION


分子量: 65.409 Da / 分子数: 15 / 由来タイプ: 合成 / 式: Zn
#88: 化合物 ChemComp-OS / OSMIUM ION


分子量: 190.230 Da / 分子数: 1 / 由来タイプ: 合成 / 式: Os
#89: 水 ChemComp-HOH / water


分子量: 18.015 Da / 分子数: 503 / 由来タイプ: 天然 / 式: H2O

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詳細

研究の焦点であるリガンドがあるかY
Has protein modificationY

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実験情報

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実験

実験手法: X線回折 / 使用した結晶の数: 1

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試料調製

結晶マシュー密度: 2.93 Å3/Da / 溶媒含有率: 58.03 %
結晶化温度: 277.15 K / 手法: 蒸気拡散法, ハンギングドロップ法
詳細: ll lissoclimides/80S complexes were formed in 5.5 mM Tris-acetate at pH 7.0, 3 mM K(OAc) at pH 7.2, 5.5 mM NH4(OAc), 2 mM Mg(OAc)2, 1.3 mM DTT by incubation of 80S ribosomes (1.5 uM) with 30- ...詳細: ll lissoclimides/80S complexes were formed in 5.5 mM Tris-acetate at pH 7.0, 3 mM K(OAc) at pH 7.2, 5.5 mM NH4(OAc), 2 mM Mg(OAc)2, 1.3 mM DTT by incubation of 80S ribosomes (1.5 uM) with 30-fold molar excess of lissoclimide congeners for 15 min at 30 C. Crystals were grown at 4 C by hanging-drop vapor diffusion

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データ収集

回折平均測定温度: 100 K / Serial crystal experiment: N
放射光源由来: シンクロトロン / サイト: SLS / ビームライン: X10SA / 波長: 1 Å
検出器タイプ: DECTRIS EIGER X 16M / 検出器: PIXEL / 日付: 2022年5月10日
放射プロトコル: SINGLE WAVELENGTH / 単色(M)・ラウエ(L): M / 散乱光タイプ: x-ray
放射波長波長: 1 Å / 相対比: 1
反射解像度: 3.16→210 Å / Num. obs: 2409467 / % possible obs: 98.2 % / 冗長度: 7 % / Biso Wilson estimate: 90.15 Å2 / CC1/2: 0.98 / Rmerge(I) obs: 0.1243 / Rrim(I) all: 0.1757 / Net I/av σ(I): 0.7 / Net I/σ(I): 30
反射 シェル解像度: 3.16→3.27 Å / Mean I/σ(I) obs: 0.7 / Num. unique obs: 1215791 / CC1/2: 0.2 / % possible all: 98.2

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解析

ソフトウェア
名称バージョン分類
PHENIX1.20.1_4487精密化
PHENIX1.20.1_4487精密化
XDSデータ削減
XSCALEデータスケーリング
PHENIX位相決定
精密化構造決定の手法: 分子置換 / 解像度: 3.16→206.3 Å / SU ML: 0.537 / 交差検証法: FREE R-VALUE / σ(F): 1.34 / 位相誤差: 26.9598
立体化学のターゲット値: GeoStd + Monomer Library + CDL v1.2
Rfactor反射数%反射
Rfree0.2505 49476 2.06 %
Rwork0.2231 2357815 -
obs0.2237 2407291 98.13 %
溶媒の処理減衰半径: 0.9 Å / VDWプローブ半径: 1.1 Å / 溶媒モデル: FLAT BULK SOLVENT MODEL
原子変位パラメータBiso mean: 103.67 Å2
精密化ステップサイクル: LAST / 解像度: 3.16→206.3 Å
タンパク質核酸リガンド溶媒全体
原子数178030 222470 8732 0 409232
拘束条件
Refine-IDタイプDev ideal数
X-RAY DIFFRACTIONf_bond_d0.0082436337
X-RAY DIFFRACTIONf_angle_d1.2438647019
X-RAY DIFFRACTIONf_chiral_restr0.05179196
X-RAY DIFFRACTIONf_plane_restr0.009463947
X-RAY DIFFRACTIONf_dihedral_angle_d16.1282150116
LS精密化 シェル
解像度 (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkRefine-ID% reflection obs (%)
3.16-3.20.393519750.382878284X-RAY DIFFRACTION98
3.2-3.230.37149850.364979604X-RAY DIFFRACTION98.71
3.23-3.270.380419820.358378920X-RAY DIFFRACTION98.83
3.27-3.310.365819880.347978711X-RAY DIFFRACTION98.86
3.31-3.360.34949910.337679976X-RAY DIFFRACTION98.89
3.36-3.40.352819830.334178750X-RAY DIFFRACTION98.89
3.4-3.450.341419840.32678790X-RAY DIFFRACTION98.82
3.45-3.50.3289890.316479890X-RAY DIFFRACTION98.88
3.5-3.560.324919780.307979177X-RAY DIFFRACTION98.9
3.56-3.620.311619880.301178676X-RAY DIFFRACTION98.81
3.62-3.680.29579930.291479667X-RAY DIFFRACTION98.65
3.68-3.750.312619800.27578323X-RAY DIFFRACTION98.22
3.75-3.820.295319850.261377340X-RAY DIFFRACTION96.98
3.82-3.90.27319920.245471895X-RAY DIFFRACTION89.3
3.9-3.980.253919800.231178875X-RAY DIFFRACTION98.68
3.98-4.070.248819860.221979284X-RAY DIFFRACTION99.45
4.07-4.180.23859940.212880211X-RAY DIFFRACTION99.39
4.18-4.290.24519850.212779353X-RAY DIFFRACTION99.36
4.29-4.420.236119770.207779006X-RAY DIFFRACTION99.3
4.42-4.560.22859900.192580289X-RAY DIFFRACTION99.27
4.56-4.720.21219820.181879298X-RAY DIFFRACTION99.32
4.72-4.910.198819830.174279069X-RAY DIFFRACTION99.25
4.91-5.130.20939870.176880091X-RAY DIFFRACTION99
5.13-5.40.212619790.175278338X-RAY DIFFRACTION98.24
5.4-5.740.201919640.175872935X-RAY DIFFRACTION91.72
5.74-6.190.21829900.174179113X-RAY DIFFRACTION97.9
6.19-6.810.20819780.183479547X-RAY DIFFRACTION99.66
6.81-7.790.210419780.182579319X-RAY DIFFRACTION99.53
7.79-9.820.22629850.196579689X-RAY DIFFRACTION98.56
9.82-206.30.231619450.19875395X-RAY DIFFRACTION94.62
精密化 TLS手法: refined / Origin x: 136.667146856 Å / Origin y: -3.53016875163 Å / Origin z: 111.317369123 Å
111213212223313233
T0.611813515326 Å2-0.0433673375949 Å20.0172349565013 Å2-0.517103504457 Å20.0389328198544 Å2--0.557808905789 Å2
L0.030835471357 °2-0.00511644665329 °20.0206696879709 °2-0.0151849128706 °20.0075452111946 °2--0.0373602945531 °2
S0.0042217687699 Å °0.0095358792411 Å °0.0114548898595 Å °0.00732173537747 Å °-0.00809551272153 Å °-0.0113601547913 Å °0.00310854261945 Å °-0.00933761061676 Å °0.00189851867368 Å °
精密化 TLSグループSelection details: all

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

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2020年3月5日: 新型コロナウイルスの構造データ

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