登録情報 | データベース: PDB / ID: 8ovu |
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タイトル | Human titin immunoglobulin-like 21 domain |
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要素 | Titin |
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キーワード | STRUCTURAL PROTEIN / Titin / Muscle / Immunoglobulin-like |
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機能・相同性 | 機能・相同性情報
sarcomerogenesis / structural molecule activity conferring elasticity / telethonin binding / skeletal muscle myosin thick filament assembly / cardiac myofibril assembly / muscle alpha-actinin binding / detection of muscle stretch / cardiac muscle tissue morphogenesis / regulation of catalytic activity / cardiac muscle hypertrophy ...sarcomerogenesis / structural molecule activity conferring elasticity / telethonin binding / skeletal muscle myosin thick filament assembly / cardiac myofibril assembly / muscle alpha-actinin binding / detection of muscle stretch / cardiac muscle tissue morphogenesis / regulation of catalytic activity / cardiac muscle hypertrophy / mitotic chromosome condensation / Striated Muscle Contraction / actinin binding / M band / I band / cardiac muscle cell development / regulation of protein kinase activity / structural constituent of muscle / sarcomere organization / skeletal muscle thin filament assembly / striated muscle thin filament / striated muscle contraction / cardiac muscle contraction / protein kinase A signaling / condensed nuclear chromosome / muscle contraction / positive regulation of protein secretion / Z disc / response to calcium ion / : / actin filament binding / Platelet degranulation / protein tyrosine kinase activity / protease binding / non-specific serine/threonine protein kinase / calmodulin binding / phosphorylation / protein serine kinase activity / protein serine/threonine kinase activity / calcium ion binding / positive regulation of gene expression / protein kinase binding / enzyme binding / extracellular exosome / extracellular region / ATP binding / identical protein binding / cytosol類似検索 - 分子機能 PPAK motif / PPAK motif / Titin, Z repeat / Titin Z / MyBP-C, tri-helix bundle domain / Tri-helix bundle domain / Immunoglobulin I-set / Immunoglobulin I-set domain / Fibronectin type III domain / Fibronectin type 3 domain ...PPAK motif / PPAK motif / Titin, Z repeat / Titin Z / MyBP-C, tri-helix bundle domain / Tri-helix bundle domain / Immunoglobulin I-set / Immunoglobulin I-set domain / Fibronectin type III domain / Fibronectin type 3 domain / Immunoglobulin subtype 2 / Immunoglobulin C-2 Type / Immunoglobulin V-Type / Fibronectin type-III domain profile. / Fibronectin type III / Fibronectin type III superfamily / Immunoglobulin V-set domain / Immunoglobulin subtype / Immunoglobulin / Tyrosine-protein kinase, active site / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Protein kinase domain / Immunoglobulin-like fold / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.95 Å |
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データ登録者 | Martinez-Martin, I. / Crousilles, A. / Mortensen, S.A. / Alegre-Cebollada, J. / Wilmanns, M. |
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資金援助 | スペイン, 3件 組織 | 認可番号 | 国 |
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Ministerio de Ciencia e Innovacion (MCIN) | BIO2017-83640-P | スペイン | Ministerio de Ciencia e Innovacion (MCIN) | PID2020-120426GB-I00 | スペイン | La Caixa Foundation | LCF/BQ/DR20/11790009 | スペイン |
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引用 | ジャーナル: Cell Rep / 年: 2023 タイトル: Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy. 著者: Martinez-Martin, I. / Crousilles, A. / Ochoa, J.P. / Velazquez-Carreras, D. / Mortensen, S.A. / Herrero-Galan, E. / Delgado, J. / Dominguez, F. / Garcia-Pavia, P. / de Sancho, D. / Wilmanns, ...著者: Martinez-Martin, I. / Crousilles, A. / Ochoa, J.P. / Velazquez-Carreras, D. / Mortensen, S.A. / Herrero-Galan, E. / Delgado, J. / Dominguez, F. / Garcia-Pavia, P. / de Sancho, D. / Wilmanns, M. / Alegre-Cebollada, J. |
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履歴 | 登録 | 2023年4月26日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2023年11月29日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年12月20日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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改定 1.2 | 2024年1月10日 | Group: Database references / カテゴリ: citation / Item: _citation.journal_volume |
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