Entry | Database: PDB / ID: 8ou1 |
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Title | Crystal structure of the SPOC domain of mouse SPOCD1 |
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Components | SPOC domain-containing protein 1 |
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Keywords | GENE REGULATION / piRNA PIWI DNA methylation Germline |
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Function / homology | Function and homology information
: / transposable element silencing / regulatory ncRNA-mediated gene silencing / chromosome / spermatogenesis / cell differentiation / DNA-templated transcription / nucleusSimilarity search - Function Spen paralogue and orthologue SPOC, C-terminal / SPOC domain / Transcription factor S-II (TFIIS), central domain / Domain in the central regions of transcription elongation factor S-II (and elsewhere) / Transcription elongation factor S-II, central domain / Transcription elongation factor S-II, central domain superfamily / TFIIS central domain profile.Similarity search - Domain/homology |
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Biological species | Mus musculus (house mouse) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.7 Å |
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Authors | Heep, M. / Cook, A.G. / O'Carroll, D. |
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Funding support | United Kingdom, 3items Organization | Grant number | Country |
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Wellcome Trust | 106144 | United Kingdom | Wellcome Trust | 200898 | United Kingdom | Wellcome Trust | 203149 | United Kingdom |
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Citation | Journal: Mol.Cell / Year: 2024 Title: C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line. Authors: Zoch, A. / Konieczny, G. / Auchynnikava, T. / Stallmeyer, B. / Rotte, N. / Heep, M. / Berrens, R.V. / Schito, M. / Kabayama, Y. / Schopp, T. / Kliesch, S. / Houston, B. / Nagirnaja, L. / ...Authors: Zoch, A. / Konieczny, G. / Auchynnikava, T. / Stallmeyer, B. / Rotte, N. / Heep, M. / Berrens, R.V. / Schito, M. / Kabayama, Y. / Schopp, T. / Kliesch, S. / Houston, B. / Nagirnaja, L. / O'Bryan, M.K. / Aston, K.I. / Conrad, D.F. / Rappsilber, J. / Allshire, R.C. / Cook, A.G. / Tuttelmann, F. / O'Carroll, D. |
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History | Deposition | Apr 21, 2023 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Feb 21, 2024 | Provider: repository / Type: Initial release |
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Revision 1.1 | Feb 28, 2024 | Group: Database references / Category: citation / citation_author / Item: _citation.pdbx_database_id_PubMed / _citation.title |
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Revision 1.2 | Apr 3, 2024 | Group: Database references / Category: citation / Item: _citation.journal_volume / _citation.page_first |
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