登録情報 | データベース: PDB / ID: 8kg2 |
---|
タイトル | Crystal structure of p97-N/D1 hexamer in complex with FAF1-UBX domain |
---|
要素 | - FAS-associated factor 1
- Transitional endoplasmic reticulum ATPase
|
---|
キーワード | PROTEIN BINDING / valosin-containing protein / Fas-associated factor 1 / ubiquitin-regulatory X |
---|
機能・相同性 | 機能・相同性情報
ooplasm / positive regulation of extrinsic apoptotic signaling pathway via death domain receptors / CD95 death-inducing signaling complex / : / flavin adenine dinucleotide catabolic process / VCP-NSFL1C complex / endosome to lysosome transport via multivesicular body sorting pathway / endoplasmic reticulum stress-induced pre-emptive quality control / cellular response to arsenite ion / BAT3 complex binding ...ooplasm / positive regulation of extrinsic apoptotic signaling pathway via death domain receptors / CD95 death-inducing signaling complex / : / flavin adenine dinucleotide catabolic process / VCP-NSFL1C complex / endosome to lysosome transport via multivesicular body sorting pathway / endoplasmic reticulum stress-induced pre-emptive quality control / cellular response to arsenite ion / BAT3 complex binding / protein-DNA covalent cross-linking repair / Derlin-1 retrotranslocation complex / cytoplasm protein quality control / positive regulation of protein K63-linked deubiquitination / positive regulation of oxidative phosphorylation / : / aggresome assembly / mitotic spindle disassembly / deubiquitinase activator activity / regulation of protein localization to chromatin / ubiquitin-modified protein reader activity / protein kinase regulator activity / VCP-NPL4-UFD1 AAA ATPase complex / vesicle-fusing ATPase / cellular response to misfolded protein / positive regulation of mitochondrial membrane potential / negative regulation of protein localization to chromatin / K48-linked polyubiquitin modification-dependent protein binding / regulation of aerobic respiration / retrograde protein transport, ER to cytosol / stress granule disassembly / positive regulation of ATP biosynthetic process / regulation of synapse organization / ATPase complex / ubiquitin-specific protease binding / regulation of protein catabolic process / MHC class I protein binding / ubiquitin-like protein ligase binding / RHOH GTPase cycle / polyubiquitin modification-dependent protein binding / autophagosome maturation / endoplasmic reticulum to Golgi vesicle-mediated transport / NF-kappaB binding / negative regulation of hippo signaling / HSF1 activation / translesion synthesis / interstrand cross-link repair / regulation of cell adhesion / ATP metabolic process / proteasomal protein catabolic process / Protein methylation / endoplasmic reticulum unfolded protein response / Attachment and Entry / ERAD pathway / heat shock protein binding / lipid droplet / proteasome complex / viral genome replication / Josephin domain DUBs / ubiquitin binding / positive regulation of DNA replication / N-glycan trimming in the ER and Calnexin/Calreticulin cycle / negative regulation of smoothened signaling pathway / macroautophagy / positive regulation of protein-containing complex assembly / Hh mutants are degraded by ERAD / Hedgehog ligand biogenesis / establishment of protein localization / Defective CFTR causes cystic fibrosis / Translesion Synthesis by POLH / positive regulation of non-canonical NF-kappaB signal transduction / ADP binding / ABC-family proteins mediated transport / autophagy / positive regulation of protein catabolic process / cytoplasmic stress granule / Aggrephagy / azurophil granule lumen / KEAP1-NFE2L2 pathway / Ovarian tumor domain proteases / positive regulation of canonical Wnt signaling pathway / nuclear envelope / positive regulation of proteasomal ubiquitin-dependent protein catabolic process / E3 ubiquitin ligases ubiquitinate target proteins / double-strand break repair / site of double-strand break / Neddylation / cellular response to heat / ubiquitin-dependent protein catabolic process / protein phosphatase binding / secretory granule lumen / regulation of apoptotic process / proteasome-mediated ubiquitin-dependent protein catabolic process / ficolin-1-rich granule lumen / Attachment and Entry / protein ubiquitination / ciliary basal body / positive regulation of apoptotic process / protein domain specific binding / DNA repair類似検索 - 分子機能 FAS-associated factor 1-like, UBX domain / FAF1, UBA-like domain / : / Fas-associated factor 1 / UAS / : / UAS / Domain present in ubiquitin-regulatory proteins / UBX domain / UBX domain ...FAS-associated factor 1-like, UBX domain / FAF1, UBA-like domain / : / Fas-associated factor 1 / UAS / : / UAS / Domain present in ubiquitin-regulatory proteins / UBX domain / UBX domain / UBX domain profile. / UBA-like domain / AAA ATPase, CDC48 family / Cell division protein 48 (CDC48), N-terminal domain / CDC48, N-terminal subdomain / Cell division protein 48 (CDC48) N-terminal domain / CDC48, domain 2 / Cell division protein 48 (CDC48), domain 2 / Cell division protein 48 (CDC48) domain 2 / CDC48 domain 2-like superfamily / : / Aspartate decarboxylase-like domain superfamily / AAA ATPase, AAA+ lid domain / AAA+ lid domain / ATPase, AAA-type, conserved site / AAA-protein family signature. / ATPase family associated with various cellular activities (AAA) / ATPase, AAA-type, core / Thioredoxin-like superfamily / Ubiquitin-like domain superfamily / ATPases associated with a variety of cellular activities / AAA+ ATPase domain / P-loop containing nucleoside triphosphate hydrolase類似検索 - ドメイン・相同性 ADENOSINE-5'-DIPHOSPHATE / Transitional endoplasmic reticulum ATPase / FAS-associated factor 1類似検索 - 構成要素 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 3.1 Å |
---|
データ登録者 | Kang, W. |
---|
資金援助 | 韓国, 2件 組織 | 認可番号 | 国 |
---|
National Research Foundation (NRF, Korea) | 2021R1A6A1A10044154 | 韓国 | National Research Foundation (NRF, Korea) | 2022R1C1C1004221 | 韓国 |
|
---|
引用 | ジャーナル: J. Korean Chem. Soc. / 年: 2024 タイトル: Crystal Structure of p97-N/D1 Hexamer Complexed with FAF1 UBX Domain 著者: Kang, W. |
---|
履歴 | 登録 | 2023年8月17日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
---|
改定 1.0 | 2024年5月29日 | Provider: repository / タイプ: Initial release |
---|
|
---|