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基本情報
登録情報 | データベース: PDB / ID: 8ge0 | ||||||
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タイトル | Crystal structure of JADE1 PZP domain in complex with Histone H3 | ||||||
![]() | Histone H3.1,Protein Jade-1 | ||||||
![]() | TRANSCRIPTION / histone acetylation / transcription activation / Nucleosome / pVHL | ||||||
機能・相同性 | ![]() regulation of DNA biosynthetic process / negative regulation of G1/S transition of mitotic cell cycle / regulation of DNA replication / histone acetyltransferase complex / Chromatin modifying enzymes / telomere organization / Interleukin-7 signaling / RNA Polymerase I Promoter Opening / Assembly of the ORC complex at the origin of replication / Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex ...regulation of DNA biosynthetic process / negative regulation of G1/S transition of mitotic cell cycle / regulation of DNA replication / histone acetyltransferase complex / Chromatin modifying enzymes / telomere organization / Interleukin-7 signaling / RNA Polymerase I Promoter Opening / Assembly of the ORC complex at the origin of replication / Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex / DNA methylation / Condensation of Prophase Chromosomes / ciliary basal body / Chromatin modifications during the maternal to zygotic transition (MZT) / HCMV Late Events / SIRT1 negatively regulates rRNA expression / ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression / PRC2 methylates histones and DNA / epigenetic regulation of gene expression / Regulation of endogenous retroelements by KRAB-ZFP proteins / Defective pyroptosis / Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) / HDACs deacetylate histones / RNA Polymerase I Promoter Escape / regulation of cell growth / Transcriptional regulation by small RNAs / Formation of the beta-catenin:TCF transactivating complex / negative regulation of canonical Wnt signaling pathway / RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function / Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 / negative regulation of cell growth / HDMs demethylate histones / NoRC negatively regulates rRNA expression / B-WICH complex positively regulates rRNA expression / PKMTs methylate histone lysines / Meiotic recombination / Pre-NOTCH Transcription and Translation / RMTs methylate histone arginines / Activation of anterior HOX genes in hindbrain development during early embryogenesis / HCMV Early Events / Transcriptional regulation of granulopoiesis / nucleosome assembly / structural constituent of chromatin / nucleosome / chromatin organization / RUNX1 regulates transcription of genes involved in differentiation of HSCs / HATs acetylate histones / Factors involved in megakaryocyte development and platelet production / MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis / Senescence-Associated Secretory Phenotype (SASP) / gene expression / Oxidative Stress Induced Senescence / Estrogen-dependent gene expression / transcription coactivator activity / regulation of cell cycle / nuclear speck / cadherin binding / chromatin remodeling / protein heterodimerization activity / Amyloid fiber formation / centrosome / apoptotic process / regulation of DNA-templated transcription / regulation of transcription by RNA polymerase II / protein-containing complex / DNA binding / extracellular exosome / extracellular region / nucleoplasm / nucleus / membrane / metal ion binding / plasma membrane / cytosol / cytoplasm 類似検索 - 分子機能 | ||||||
生物種 | ![]() | ||||||
手法 | ![]() ![]() ![]() | ||||||
![]() | Klein, B.J. / Liu, J. / Kutateladze, T.G. | ||||||
資金援助 | 1件
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![]() | ![]() タイトル: Guiding the HBO1 complex function through the JADE subunit. 著者: Gaurav, N. / Kanai, A. / Lachance, C. / Cox, K.L. / Liu, J. / Grzybowski, A.T. / Saksouk, N. / Klein, B.J. / Komata, Y. / Asada, S. / Ruthenburg, A.J. / Poirier, M.G. / Cote, J. / Yokoyama, A. / Kutateladze, T.G. | ||||||
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