登録情報 | データベース: PDB / ID: 8enp |
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タイトル | UBE3A isoform 3 AZUL |
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要素 | Isoform III of Ubiquitin-protein ligase E3A |
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キーワード | LIGASE / ubiquitin ligase / proteasome interaction |
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機能・相同性 | 機能・相同性情報
sperm entry / positive regulation of Golgi lumen acidification / motor learning / negative regulation of dendritic spine morphogenesis / regulation of ubiquitin-dependent protein catabolic process / prostate gland growth / HECT-type E3 ubiquitin transferase / progesterone receptor signaling pathway / androgen receptor signaling pathway / locomotory exploration behavior ...sperm entry / positive regulation of Golgi lumen acidification / motor learning / negative regulation of dendritic spine morphogenesis / regulation of ubiquitin-dependent protein catabolic process / prostate gland growth / HECT-type E3 ubiquitin transferase / progesterone receptor signaling pathway / androgen receptor signaling pathway / locomotory exploration behavior / protein autoubiquitination / protein K48-linked ubiquitination / ovarian follicle development / negative regulation of TORC1 signaling / cellular response to brain-derived neurotrophic factor stimulus / proteasome complex / response to cocaine / positive regulation of protein ubiquitination / response to progesterone / regulation of synaptic plasticity / response to hydrogen peroxide / regulation of circadian rhythm / brain development / protein polyubiquitination / ubiquitin-protein transferase activity / ubiquitin protein ligase activity / rhythmic process / Antigen processing: Ubiquitination & Proteasome degradation / ubiquitin-dependent protein catabolic process / proteasome-mediated ubiquitin-dependent protein catabolic process / transcription coactivator activity / positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / glutamatergic synapse / positive regulation of transcription by RNA polymerase II / proteolysis / nucleus / metal ion binding / cytosol類似検索 - 分子機能 Ubiquitin-protein ligase E3A / Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain / Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily / Amino-terminal Zinc-binding domain of ubiquitin ligase E3A / Ubiquitin-protein ligase E3B/C / HECT domain / HECT, E3 ligase catalytic domain / HECT-domain (ubiquitin-transferase) / HECT domain profile. / Domain Homologous to E6-AP Carboxyl Terminus with 類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / simulated annealing |
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データ登録者 | Bregnard, T.A. / Bezsonova, I. |
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資金援助 | 米国, 3件 組織 | 認可番号 | 国 |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | R35 GM128864 | 米国 | National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | R21 AI135451 | 米国 | National Science Foundation (NSF, United States) | NSF 1616184 | 米国 |
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引用 | ジャーナル: To Be Published タイトル: Differences in structure, dynamics and Zn-coordination between isoforms of human ubiquitin ligase UBE3A 著者: Bregnard, T.A. / Fairchild, D. / Chen, X. / Erlandsen, H. / Walters, K.J. / Korzhnev, D.M. / Bezsonova, I. |
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履歴 | 登録 | 2022年9月30日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2023年10月18日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2024年5月15日 | Group: Database references / カテゴリ: database_2 / Item: _database_2.pdbx_DOI |
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