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- PDB-8eaw: An asymmetric disk assembly formed by tandem dimers of the tobacc... -

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Basic information

Entry
Database: PDB / ID: 8eaw
TitleAn asymmetric disk assembly formed by tandem dimers of the tobacco mosaic viral capsid protein (TMV)
ComponentsCapsid protein
KeywordsVIRAL PROTEIN / Viral capsid proteins / tobacco mosaic virus / protein assembly
Function / homologyTobacco mosaic virus-like, coat protein / Tobacco mosaic virus-like, coat protein superfamily / Virus coat protein (TMV like) / helical viral capsid / structural molecule activity / identical protein binding / Capsid protein
Function and homology information
Biological speciesTobacco mosaic virus
MethodX-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.8 Å
AuthorsDai, J. / Pereira, J.H. / Adams, P.D. / Francis, M.B.
Funding support United States, 1items
OrganizationGrant numberCountry
Department of Energy (DOE, United States)DEAC02-05CH11231 United States
CitationJournal: Small / Year: 2023
Title: A Membrane-Associated Light-Harvesting Model is Enabled by Functionalized Assemblies of Gene-Doubled TMV Proteins.
Authors: Dai, J. / Wilhelm, K.B. / Bischoff, A.J. / Pereira, J.H. / Dedeo, M.T. / Garcia-Almedina, D.M. / Adams, P.D. / Groves, J.T. / Francis, M.B.
History
DepositionAug 29, 2022Deposition site: RCSB / Processing site: RCSB
Revision 1.0Mar 1, 2023Provider: repository / Type: Initial release
Revision 1.1Oct 25, 2023Group: Data collection / Refinement description
Category: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model
Revision 1.2May 1, 2024Group: Database references / Category: citation / citation_author
Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title / _citation_author.identifier_ORCID

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

Downloads & links

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Assembly

Deposited unit
a: Capsid protein
b: Capsid protein
c: Capsid protein
d: Capsid protein
e: Capsid protein
f: Capsid protein
g: Capsid protein
h: Capsid protein
i: Capsid protein
j: Capsid protein
k: Capsid protein
l: Capsid protein
m: Capsid protein
n: Capsid protein
o: Capsid protein
p: Capsid protein
q: Capsid protein


Theoretical massNumber of molelcules
Total (without water)603,43917
Polymers603,43917
Non-polymers00
Water00
1


  • Idetical with deposited unit
  • defined by author&software
  • Evidence: light scattering, scanning transmission electron microscopy
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Buried area93880 Å2
ΔGint-403 kcal/mol
Surface area185900 Å2
MethodPISA
Unit cell
Length a, b, c (Å)208.510, 255.500, 260.850
Angle α, β, γ (deg.)90.000, 90.000, 90.000
Int Tables number20
Space group name H-MC2221
Space group name HallC2c2
Symmetry operation#1: x,y,z
#2: x,-y,-z
#3: -x,y,-z+1/2
#4: -x,-y,z+1/2
#5: x+1/2,y+1/2,z
#6: x+1/2,-y+1/2,-z
#7: -x+1/2,y+1/2,-z+1/2
#8: -x+1/2,-y+1/2,z+1/2

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Components

#1: Protein
Capsid protein / Coat protein


Mass: 35496.395 Da / Num. of mol.: 17 / Mutation: S124C
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Tobacco mosaic virus (vulgare) / Strain: vulgare / Gene: CP / Production host: Escherichia coli (E. coli) / References: UniProt: P69687

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Experimental details

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Experiment

ExperimentMethod: X-RAY DIFFRACTION / Number of used crystals: 1

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Sample preparation

CrystalDensity Matthews: 2.88 Å3/Da / Density % sol: 57.27 %
Crystal growTemperature: 293 K / Method: vapor diffusion, sitting drop
Details: 100 mM Bis-Tris, pH 6.5, 45 % (v/v) polypropylene glycol P400

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Data collection

DiffractionMean temperature: 100 K / Serial crystal experiment: N
Diffraction sourceSource: SYNCHROTRON / Site: ALS / Beamline: 8.2.1 / Wavelength: 1 Å
DetectorType: ADSC QUANTUM 315r / Detector: CCD / Date: Mar 18, 2019
RadiationMonochromator: Double-crystal Si(111) and multilayer / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelengthWavelength: 1 Å / Relative weight: 1
ReflectionResolution: 2.8→81.44 Å / Num. obs: 169799 / % possible obs: 99.74 % / Redundancy: 8.3 % / Biso Wilson estimate: 58.83 Å2 / CC1/2: 0.996 / Net I/σ(I): 9.55
Reflection shellResolution: 2.8→2.9 Å / Redundancy: 8.1 % / Num. unique obs: 16816 / CC1/2: 0.467 / % possible all: 98.82

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Processing

Software
NameVersionClassification
PHENIX1.18.2_3874refinement
XDSdata reduction
XDSdata scaling
PHENIX1.18.2_3874phasing
RefinementMethod to determine structure: MOLECULAR REPLACEMENT
Starting model: 1EI7
Resolution: 2.8→81.44 Å / SU ML: 0.4293 / Cross valid method: FREE R-VALUE / σ(F): 1.34 / Phase error: 25.9677
Stereochemistry target values: GeoStd + Monomer Library + CDL v1.2
RfactorNum. reflection% reflection
Rfree0.2345 8362 4.93 %
Rwork0.1956 161292 -
obs0.1975 169654 99.74 %
Solvent computationShrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL
Displacement parametersBiso mean: 62.9 Å2
Refinement stepCycle: LAST / Resolution: 2.8→81.44 Å
ProteinNucleic acidLigandSolventTotal
Num. atoms38318 0 0 0 38318
Refine LS restraints
Refine-IDTypeDev idealNumber
X-RAY DIFFRACTIONf_bond_d0.002439083
X-RAY DIFFRACTIONf_angle_d0.494653312
X-RAY DIFFRACTIONf_chiral_restr0.03736239
X-RAY DIFFRACTIONf_plane_restr0.00326885
X-RAY DIFFRACTIONf_dihedral_angle_d12.535513906
LS refinement shell
Resolution (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkRefine-ID% reflection obs (%)
2.8-2.830.39272460.39455201X-RAY DIFFRACTION96.84
2.83-2.870.35452840.31085329X-RAY DIFFRACTION99.72
2.87-2.90.36692580.30485384X-RAY DIFFRACTION99.91
2.9-2.940.33772780.35347X-RAY DIFFRACTION99.88
2.94-2.980.35952710.29855297X-RAY DIFFRACTION99.87
2.98-3.020.33923020.28145322X-RAY DIFFRACTION99.93
3.02-3.060.31952760.26595363X-RAY DIFFRACTION99.88
3.06-3.10.33352520.27115393X-RAY DIFFRACTION99.95
3.1-3.150.30192820.26065323X-RAY DIFFRACTION99.75
3.15-3.210.31272960.25475327X-RAY DIFFRACTION99.96
3.21-3.260.3052660.26525385X-RAY DIFFRACTION99.89
3.26-3.320.32332800.27115328X-RAY DIFFRACTION99.89
3.32-3.380.30852490.23775382X-RAY DIFFRACTION99.73
3.38-3.450.28512750.24365352X-RAY DIFFRACTION99.89
3.45-3.530.30752700.22845370X-RAY DIFFRACTION99.73
3.53-3.610.25982720.20625346X-RAY DIFFRACTION99.86
3.61-3.70.25252630.20285374X-RAY DIFFRACTION99.86
3.7-3.80.22593080.18215375X-RAY DIFFRACTION99.93
3.8-3.910.21122780.17965358X-RAY DIFFRACTION99.84
3.91-4.040.21322800.1655385X-RAY DIFFRACTION99.89
4.04-4.180.20292820.1685391X-RAY DIFFRACTION99.91
4.18-4.350.1942970.14525372X-RAY DIFFRACTION99.93
4.35-4.550.18563020.15085371X-RAY DIFFRACTION99.95
4.55-4.790.17272910.14485366X-RAY DIFFRACTION99.96
4.79-5.090.18933010.13785408X-RAY DIFFRACTION99.96
5.09-5.480.19082920.14955424X-RAY DIFFRACTION99.95
5.48-6.030.22882780.18395425X-RAY DIFFRACTION100
6.03-6.90.21852700.18185499X-RAY DIFFRACTION99.91
6.9-8.70.16532790.15065485X-RAY DIFFRACTION99.81
8.7-81.440.18362840.17235610X-RAY DIFFRACTION98.71
Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

IDL112)L122)L132)L222)L232)L332)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T112)T122)T132)T222)T232)T332)Origin x (Å)Origin y (Å)Origin z (Å)
14.335285640190.627743748638-2.030999679596.538246620051.8619814166.77198696636-0.0385449162508-0.6228516612160.1845202927530.301753495589-0.173447408010.776811311247-0.4648515012230.1093023856110.06087991089510.5062250021720.0104413050146-0.01005153056940.623323738261-0.1288177246770.38097508206-195.96224198144.83570575171.3351632374
27.83406232715-0.7774784842470.4621125468276.551933321485.069664691364.30921626226-0.146074730512-0.196060211070.231017283524-0.5829882014050.9873761832220.105069462734-0.850886450971-0.126798991955-0.1601971232090.497062368466-0.0110217907020.03051655851190.4473375965070.099535261070.347776400114-191.569972823137.37882283659.7241694419
31.76661595174-0.287404881659-1.958710719072.787813028893.294004774894.87490258695-0.1663876676430.5702245141650.0551712800775-0.6854067127250.370553793767-0.131242037906-0.0003834442097430.249442146040.03756730982580.395910299523-0.00111478875251-0.03742657379780.3756279260010.0336185379310.415105839542-192.079459316128.43256272247.2769611177
46.17020644187-4.17809491535-4.762278456383.979532584883.924357584556.189304024970.101097607917-0.2926641161670.314615559127-0.2241373484780.153877937828-0.276378394388-0.2434397137790.312061713539-0.2021184327980.436577113917-0.0348117443961-0.08930513149060.5046144851930.0367308527930.408173036559-186.946901281117.86046737153.6048032955
58.586442936256.002539538055.611860167294.536149017792.756176465989.788299103540.5206289211940.365440388831-0.573343563667-0.257442692412-0.185610901113-1.055323118-0.2730782412030.77505472865-0.663329593850.3940586819250.0155305496505-0.004427772038570.4763099006690.03532611728350.399832584526-188.657646548135.58486115359.2880581141
64.051015887071.772798450062.149907005662.563360841312.542299457076.7220263099-0.362774921256-0.701696996518-0.420190015321-0.0509729078220.521488653038-2.66488386906-1.14418985474-0.633471219069-0.2018159252230.752754383043-0.0294139683212-0.08159303646940.4797837178060.06124827149580.555928671972-187.924714096146.73031755266.0990291125
73.324823719292.021042208012.163388670448.457015509016.738297689515.48293839881-0.294346263477-0.08262889282840.437661310248-0.1398715925340.7979073372790.0124208844989-1.446463062750.1550327398930.1779797370610.7064458611540.07413521320910.005277068802890.4954027453530.1050682980040.380390520583-192.535937859149.67560908657.0388583057
87.984903586070.8503802619291.774187116265.530371632734.434988043594.714605880970.133326003311-0.4387661599290.485712690987-0.626735455484-0.170499901951-0.2969214305760.4619181648760.3648578191840.1360483064740.339396012180.051903995524-0.01491452585230.4561438643650.02571859527340.198428051132-197.633190365136.70575721758.8097800455
93.05818259821-1.88842049707-0.3246928506575.212172587440.32350683692.051490279630.1635379783620.140017942599-0.08029593511550.438831766257-0.183349811799-0.6705140545820.3621452238210.158389548135-0.1289662022870.3912346318120.0314230596635-0.02299801965540.5778988938980.04751194061210.355443619434-192.066002771115.62034789160.7807537813
103.34837056923-4.03633213911.37315160655.884446483370.5116067501152.68318838782-0.11515177222-0.357979399182-0.760324793812-0.3236329119670.6471207530720.8892764941920.565051806319-0.162388366362-0.4016952258650.359059210584-0.0339837235203-0.005889564736810.4135128519640.06210133095040.415192368381-197.015437091115.61081686353.9285365306
116.434953636990.282834394004-0.04667332738422.11294288752.82137522282.70227092720.408385865378-0.1112643185170.4162623171223.34107709742E-5-0.2601924476460.210749985254-3.18931427028-1.538336096520.7838993903010.9534373124890.1039024468950.08793310454210.4855576586420.01022242510010.485469240943-197.308637788150.7233464764.0001248261
122.55085590862-1.68471082411-0.04326713698156.80269456992-3.730553520127.282084396510.05160048435970.368826659652-0.1243772557610.2309429474740.2203915132040.316421013364-0.838714971114-0.417229911863-0.3460741970790.343113652661-0.0615732873542-0.004132225851610.474815964228-0.04490497347320.317158659196-171.12719245136.00514802269.1636166197
134.47152742036-0.8159415731063.38186370154.1912696529-4.221618913245.08211927686-0.523444527578-0.0793770880795-0.624588147783-0.3555059074470.5903009475230.7564055712640.30014626753-0.796594897238-0.1597691348640.393362902171-0.061309224245-0.0003630449269430.493125777806-0.005930545834060.491359469261-172.910579285115.49149627173.198405847
148.92668184658-4.991132679392.531762272538.28547048046-3.562858966625.034923693470.07897248194690.0658328250147-0.1900240320.774400264402-0.1537212841750.500281687504-0.4784754376-0.2580390493240.11082106270.436109591029-0.06600062452780.02879969925660.408019938004-0.01127103598070.299566466565-173.168322763139.91630610769.6562685684
151.02679949057-0.4848794503490.1674129823057.333683324931.652788334352.68141386855-0.1346441661270.590805267401-0.173022663651-0.8845723156320.02374863180250.4452626673110.2441285626670.2887501061760.05597452922620.369224099717-0.0578772232398-0.03914721054260.4560132643060.01083274288290.297525362875-163.867386875121.46152133368.0056181178
166.916358656210.85410894859-0.4792899590996.628625368354.588993757537.72546475394-0.3689428706970.212071462785-0.7611715031981.063628157140.877175049021-0.9383174200440.8239442468580.68091702329-0.6049166978270.4330430833080.0571494455134-0.007796136904510.506543833095-0.007893709590850.411390882773-160.338227303115.45327379375.6080241498
173.21700295489-1.068540056523.929300130861.49946355548-0.567887945346.64605035163-0.2481767749510.1574081108550.4374605409480.08050152350150.179152669651-0.561094320049-0.5987952562710.226097048392-0.005914455436590.488417317833-0.133807471975-0.002486877461080.4182061927660.02543210050720.43642721508-168.203476338146.87171560269.168014221
184.72083047122-1.617981692540.9917325370264.41732520525-0.7535174029621.65840571483-0.232037260499-0.823843854033-0.4946107002530.4550421513580.657970415030.0287784335986-0.8357309270410.464194598655-0.2234915531870.701284112492-0.003218018319050.04048002754680.565001218016-0.05396802311460.297177472476-192.932765853136.99786852598.721094918
197.685624797-1.101497786890.1390577013937.782919760764.195322378612.572816291190.332595769132-0.9257792948290.23394917154-0.4926254871220.9013703937410.523241240713-0.4629249073751.82319599773-0.4022041058540.478988220639-0.01411450368710.0604947651070.614569349932-0.01354136399080.532384132507-188.743346806134.00749782285.131842054
200.504182267664-0.509829093116-1.68029740718.530749045395.541707595686.828825626690.0995793678193-0.159289572890.0431623157828-0.290238538920.55747907445-0.72941710855-0.3451004553250.742338540175-0.4804158777590.366427419133-0.01699557765820.03617657676010.3971451067080.04934267771580.245367451209-189.442208371130.19414164270.339384486
219.882980486362.78693589708-6.611017670133.72985948613-0.08313476271795.59836797937-0.326720601737-0.202932684412-0.233469718974-1.01764990235-0.180975704323-0.205559409218-0.0205431490577-1.106027486630.2864405040280.4648547733380.128160941419-0.07903047251950.439093591570.09833431003210.309627982536-187.145012383114.87210687565.7674971118
224.1598358222-4.81909477132-4.172653367276.073655891865.246324854434.958247179750.227585394197-0.3546260389830.6771645171571.054532769710.294779910625-1.4811060274-0.07340595347440.43421763874-0.640135274510.367603352873-0.033810193585-0.07383070692530.5792580345110.01361710198910.464079705505-183.96294159119.12805442175.2622769683
236.476615444853.892571080794.85394254882.638870977182.864668351844.372722457990.2395680335730.4873344435521.13651712046-0.83379268301-0.51627680663-0.037656882758-0.05418210034770.0849232005068-1.174231049510.4338656524630.0498421165173-0.06459277213650.504306788250.07124744928240.571563528855-185.898212529132.46196944584.0757420059
244.950102135022.15228889963.626229188374.957645067945.629422103846.74626820982-0.0620548777924-1.78551484525-0.8408723454890.3149524592970.861946668424-1.628952808491.328219153070.733757161725-0.7721388531450.490207089343-0.108507435625-0.08728493400230.74464234608-0.02200572868090.629910521473-184.826361923140.34823049594.4013749549
255.73881402815-2.41490744379-1.214627895828.4738737264-2.861699278041.788144613830.797377721853-0.0913171720596-0.805403517712-1.32256451682-0.4695856316950.527552839439-3.579549744461.73140260420.5389801282980.9560085801910.08223808070440.003062303722810.574652272125-0.004720497328310.334844307932-189.205695425146.54925846687.0826228522
266.06352126001-2.35539083186-2.691485258895.847334988764.507701219473.726806934951.44623386893-0.3967384030830.718635357996-0.908991048725-0.464978701752-0.323210628209-0.7139923500030.4349413924470.8748948327890.525021410540.0161195481972-0.03856207069820.4206321098550.08855295829520.26333539161-192.429713841138.77236785182.5241834259
279.804538935051.361897339463.91581124285.282575685183.46971021854.392482710221.021174587-0.169804829097-1.389305537650.366170512177-1.280511359580.3149807162421.515132099520.9649625632650.2332471815480.4467176293310.0247983492007-0.03208363575270.7197548480840.01887125561080.349935568241-197.448259873128.81894191385.8078242589
283.81396819591-1.25077542539-2.273532687225.645006116342.224096328564.76655958654-0.0611593616368-0.267393495108-0.68651293290.001265854736630.2586979326140.4039267434740.5387568562720.648747310712-0.2260228742220.353063804031-0.00945168467799-0.1009399613430.5483894734320.03535698666320.309805308114-190.012109844113.46983165578.3701103577
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1905.68707903298-1.67046930317-0.7606307134811.3482630892.74401709445.01425925428-0.552150476885-0.270290760794-0.3668418819150.4824754664790.3261140724080.64780244784-0.1439843507870.5472878028110.2300396277040.3765291327990.06333366256710.1093127302030.3454721242430.07807347151480.444592835144-166.71359103215.083996783442.9450293931
1914.837113001141.844341583782.064558743751.70479821552.709574258237.23210982459-0.285774712633-0.1488761743050.7629730221560.3270299816030.628211932784-0.95514735613-0.4153949891680.321247399427-0.1714759725240.4511179371560.008894513898380.04171112025370.4138001729820.03356073728120.647078404013-164.72853285822.357644341935.9151119307
1923.098850422313.37241816428-1.558820505842.29580386384-2.331070911526.45017055683-0.0595771979957-0.583978766906-0.513098673772-0.351699149433-0.006296106807810.04218631500860.9992655484140.4177530376990.3472981798360.6525515264890.1201328916770.1808788655890.5005823229460.00443621620190.873407999544-171.729257168-9.716360738538.2199131637
1935.25892634558-0.8683714334622.332809945683.86135498355-0.5922296929874.51252202320.2343745087020.5865479892860.9977547808010.0387068784199-0.2453335687250.5004224836930.2208049756270.6073863271760.1446988508290.629271112872-0.001692150814090.1182683950020.565591879691-0.07999493267080.728665583353-202.0582961875.1235993317717.1100715172
1943.577035786441.337089565021.837675896815.06149154107-1.434466208172.88940446781-0.6237205123310.002471399637050.08068753083010.6250119896430.217289024230.1643265073960.5446032853320.848470923514-0.1308729132010.537993752470.01495140623230.1371590931680.501598084825-0.1075479315190.861132422078-194.9516073195.6457801262829.6962399822
1951.121468734891.483376410892.723157859644.737822973775.101204769336.577075468930.1455625064490.06819705140170.235275336812-0.05308067780550.235842246743-0.4790242520010.293961070184-0.0499061457914-0.3040455205480.5443441524150.02396236079920.07899692459750.4708126945030.005035472246150.702767052991-192.3957756646.5573165532744.715995215
1963.853634952852.232727627581.65867138296.418980508664.431034291148.26287003376-0.05622306127720.0973371814533-0.184153709892-0.180138880020.275342609454-0.05068468729540.07850287028931.0555649078-0.2612021730770.3594734968570.003199293197760.1809966762450.476739091621-0.0008500596677250.597186949053-188.03127044518.945553528943.9400916362
1972.050676854985.16485780516-2.526232810888.827716726836.648614679642.049538639311.05169477111-1.60306235429-1.667062915210.522247317499-0.127793524629-1.642704239460.8195572652651.757989412340.419110150320.35094521826-0.04362222499730.3364109933730.616841834023-0.1316898075490.54957988492-191.969522596.9938442776830.506620511
1982.000485338887.77094299430.6586077883879.62105856954-6.126186368539.47858671060.2779660718172.05954064659-0.296999551536-1.520198169273.21591770705-0.877831069818-0.01865102878430.03036599018991.93319229680.3954929714860.1343924500020.2629066636430.641179459893-0.1894791009471.17823502833-193.08388671.3017792732419.0242792148
1995.41700942633-2.468708425753.443289691067.349823319054.128189579832.008018793430.419800582813-0.284179304653-0.4105631740960.6290411925160.165927012830.6350664006194.26149999549-0.222377206188-0.01720043454341.08131098545-0.1528572325440.1593562416830.592892822638-0.1273406998440.986285120728-196.183114239-6.3478800090725.6575490086
2008.458307373930.66076900453-1.438305894485.679947014452.093638691616.808440783070.219400791367-0.1958592427170.350513900968-0.01787158516030.0212214726123-0.785792946333-0.0291969720461-0.233564497426-0.09115900351210.366740912358-0.07043567387830.1445711147690.436859664248-0.009474017754460.567928822603-200.6922823215.2803268683132.0493215303
2011.81804380617-1.224941085531.994776291464.448931688960.9323729856732.20231726025-0.5016251682440.188861513573-0.0460460336416-0.5295636569060.2502445791360.0590909070051-0.5269190990510.6432814912250.1301283099960.387214880146-0.1272069311570.04077686319690.525124275585-0.002267830376760.37197257843-194.35740662724.463889614440.3410819767
2022.940176227754.235952405621.862578840764.031493477771.142365922762.97820637184-0.2243611678040.1677979384840.6442006756560.2828056435460.0335085228381.05198831872-0.3835974125910.009371902939650.2520183545240.4768490356020.02883359370690.1482347273810.386100526733-0.03016757516380.677516975595-197.7499288320.610341360947.0433857402
2033.536514807942.196857913672.351274769765.29620077483-0.3766026441235.307387843140.1070028701810.395737297313-0.726945129063-0.7204778007130.2342595886730.6172150246081.09163598793-1.655574974970.1305783431750.709789951527-0.0945912900261-0.0416704004140.557602401127-0.09073607902180.846657521813-202.295042278-3.805397229920.3148666795
2041.2490251012-0.5304166843240.2985824975643.252462383350.1052591114732.954265341140.07943298206550.126026009044-0.324970290357-0.50971959752-0.1083688679020.4684383664340.3698983126450.05011184334850.06047518186920.3079563041730.04324452829650.1801868937380.468472904069-0.03198617933090.528004818728-176.78232281812.692679709218.3432089802
2053.82698036517-1.91632308827-1.321427307152.440058045482.2230118594.80294455244-0.340620427607-0.0360045584270.05134381123840.5676259279260.5218731728-0.110533136055-0.00998396418921-0.1597219725640.0242801781030.3976320930490.03847439929660.130526278280.558178055074-0.00363937333480.667030019911-178.12486441732.053802711926.0787526667
2062.63130239535-1.059767270150.2156056215122.426739254860.6537564510782.834524029740.0222434416649-0.356339315216-0.0665997296008-0.296046061584-0.4248186681320.737606297580.189908250909-0.6392881337530.2482053121310.392053599856-0.01825738270050.1183921846840.446150377407-0.07640856415880.617824697427-179.1714622539.496700083716.2743120861
2076.995035682382.348008004131.21260598344.43813454150.7460100822054.26274576285-0.359877148279-0.7400839389310.2705601459070.2197437752540.3985851342240.201098683580.1092333673940.7099885883050.438583949060.4233508034550.03544071592660.1618575651160.467315276850.04533984115590.437151941088-168.62734622824.837658699525.3235531015
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2121.252686303560.2460356241213.304904850824.424197159870.6628940902019.006521769640.14328085922-0.106489870058-0.356713113390.397858945647-0.0855487257833-0.4109447559120.651963235146-0.02727415608390.3286703881830.3418963754830.0027026881410.1126259881790.385056453581-0.1165662313090.610429308444-194.64822466817.29537520924.1855890954
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3054.99310899739-1.182639958321.652678070572.49706719825-0.1491915146363.92972089192-0.0294954928189-0.0949453042683-0.1685188661970.5387379867710.203804495102-0.235148384346-0.03142216397960.347554124142-0.2975665867850.313903511075-0.0111125821185-0.02788430677210.400058970897-0.03953301432680.338891802295-189.028557429111.18138176135.9906453305
3065.01505484924-0.05941763982471.241193896793.835138211083.228367551033.051502767830.1018216301881.68073712718-0.219611000811-0.8842087904110.3350383248940.559998805208-0.393091099827-0.366508206951-0.1737398556140.517750925395-0.1779568354940.02871439142470.4281612354490.03176333978450.34379246622-191.46491554129.41840899334.9775554936
3072.01745759345-6.060845077651.992213589173.5160354021-5.86921393289.75084931088-1.19769392683-1.321297337430.1302635048410.598579599321-0.21330704658-1.2278131153-1.19174579246-0.834979714946-0.4988376555740.28535323582-0.182376596506-0.02884782561590.634815759862-0.04313019445460.558375897109-191.124764684142.31389940637.2430388949
3085.696323310961.29153627997-1.051564316851.246867436661.076015748412.156917735330.48686490492-1.13142504653-0.00348464260581-1.12467779561-0.4096354454581.75930922954-1.86162788739-0.242466816314-0.01636697719860.8231024046520.0733041609289-0.1554033032630.287001706948-0.003770459203120.439680434627-195.94159285141.68964758527.9038391927
3096.40711526324-0.7796346689520.4185136352716.889714741962.213753121733.922506413090.2248752538010.1651190448320.355856807155-0.274060688729-0.186396914976-0.158721918394-0.6475428746720.0822177018590.02841987911850.361743219626-0.02329677686190.000275693036120.3481400408970.05255204405820.233990773548-200.446928621129.97862362634.257129244
3101.237841873011.77185372659-0.8151920261762.65562387436-0.1105386010053.94103326152-0.23674664588-0.317932351762-0.6399884691431.039675817970.3309269237110.1299664786790.3210071050890.17931312261-0.1500092806320.5159553551930.0321627901645-0.02692824004720.487635598281-0.04272765992680.350504212917-194.011552964111.28387107343.5485479363
3113.04989749269-3.688308520912.055070387336.069441569-0.04385956310462.602897337970.0344081176988-0.507962768447-0.4858031120120.02882231964210.4889774233730.3910328342470.589595137659-0.362557341081-0.2036614897470.463354506283-0.0578992039329-0.03463553481190.5103884341210.078742976030.383084104856-198.852658486108.56531375937.1894119197
3123.86946540104-3.256225135940.6512989975625.798095548551.316067448257.14101862210.1607599407050.1323680489380.514249129301-0.591288716073-0.02543496635520.394059512979-1.8326607202-0.4181561985490.05633822256390.728699506720.03753578653330.03469003727010.4840962603410.03092115499580.408705841537-200.718574412144.96347035534.161660273
3132.02994600104-2.660986499191.123943101957.86148617384-5.215947923817.69755256074-0.0006589530257870.1230194933030.07656173503290.112008482215-0.0498232078001-0.100361615973-0.253600499252-0.3612191720550.09352375830140.218761330519-0.1215363397590.01338660552580.371503255652-0.01269375644240.276817201764-174.022218969134.14258276343.8473160592
3144.00934736129-0.7653770788060.01770744722135.1003333642-4.187529793313.70874810655-0.0530630037281-0.208452641115-0.0278555131641-0.6247962766460.4995346362810.4488010963050.54378613149-0.687583438747-0.5653836346080.378714695751-0.1204805547840.001782499100430.4523407798550.04588170243120.384049980702-174.981365534116.39507002954.9691979372
3152.72767949526-4.814684995823.090750411436.88002325516-5.135442620147.27509515182-0.042242782970.243771701042-0.01318938265770.502194831903-0.04639408645510.220372946969-0.544215191379-0.244461335027-0.07579367368280.389710642829-0.07547566494150.01912253086180.287414442796-0.05994031336620.355111790135-176.324514859137.91645646442.8456708788
3161.77131216517-1.265223705390.2141563477561.571956604671.155411894932.18261490507-0.1815305200620.631195191367-0.344480522491-0.492111545940.334230379925-0.1468036527880.5159579853050.389377675106-0.4175127107290.349817425345-0.00205358435525-0.03123919077210.4821971801860.02190029509010.33744596807-166.239351964120.54352294747.9556996539
3176.95068515901-1.95819793745-0.1755131608578.31805180129-1.895210913965.98864034171-0.259196961486-0.0902737029031-0.5227721464530.815365317350.0223552802972-0.8928578672910.3566549699550.445267373991-0.0297944200820.410342160318-0.0006604276986350.0384398519730.4325652549220.04791304323570.257907862436-162.413496564117.90672408257.147884653
3185.41992275489-4.541313288134.47155426585.43669877541-3.873612255877.49570115657-0.2966374595150.3535624427580.5955011530620.139521737113-0.12118477031-0.975768276805-0.543208055570.6236996419550.8795884850450.60533097003-0.107338942940.01556389440650.3509670313270.01995718359840.429420899814-171.588057158144.40179523140.0372742555
Refinement TLS group

Refine-ID: X-RAY DIFFRACTION

IDRefine TLS-IDSelection detailsAuth asym-IDLabel asym-IDAuth seq-IDLabel seq-ID
11chain 'a' and (resid 1 through 13 )aA1 - 131 - 13
22chain 'a' and (resid 14 through 19 )aA14 - 1914 - 19
33chain 'a' and (resid 20 through 32 )aA20 - 3220 - 32
44chain 'a' and (resid 33 through 50 )aA33 - 5033 - 50
55chain 'a' and (resid 51 through 55 )aA51 - 5551 - 55
66chain 'a' and (resid 56 through 60 )aA56 - 6056 - 60
77chain 'a' and (resid 61 through 65 )aA61 - 6561 - 65
88chain 'a' and (resid 66 through 75 )aA66 - 7566 - 75
99chain 'a' and (resid 76 through 95 )aA76 - 9576 - 95
1010chain 'a' and (resid 101 through 140 )aA101 - 14096 - 135
1111chain 'a' and (resid 141 through 155 )aA141 - 155136 - 150
1212chain 'a' and (resid 166 through 197 )aA166 - 197151 - 182
1313chain 'a' and (resid 198 through 215 )aA198 - 215183 - 200
1414chain 'a' and (resid 216 through 238 )aA216 - 238201 - 223
1515chain 'a' and (resid 239 through 255 )aA239 - 255224 - 240
1616chain 'a' and (resid 274 through 298 )aA274 - 298241 - 265
1717chain 'a' and (resid 299 through 320 )aA299 - 320266 - 287
1818chain 'b' and (resid 1 through 13 )bB1 - 131 - 13
1919chain 'b' and (resid 14 through 19 )bB14 - 1914 - 19
2020chain 'b' and (resid 20 through 32 )bB20 - 3220 - 32
2121chain 'b' and (resid 33 through 37 )bB33 - 3733 - 37
2222chain 'b' and (resid 38 through 50 )bB38 - 5038 - 50
2323chain 'b' and (resid 51 through 55 )bB51 - 5551 - 55
2424chain 'b' and (resid 56 through 60 )bB56 - 6056 - 60
2525chain 'b' and (resid 61 through 65 )bB61 - 6561 - 65
2626chain 'b' and (resid 66 through 70 )bB66 - 7066 - 70
2727chain 'b' and (resid 71 through 75 )bB71 - 7571 - 75
2828chain 'b' and (resid 76 through 95 )bB76 - 9576 - 95
2929chain 'b' and (resid 101 through 140 )bB101 - 14096 - 135
3030chain 'b' and (resid 141 through 155 )bB141 - 155136 - 150
3131chain 'b' and (resid 166 through 197 )bB166 - 197151 - 182
3232chain 'b' and (resid 198 through 215 )bB198 - 215183 - 200
3333chain 'b' and (resid 216 through 238 )bB216 - 238201 - 223
3434chain 'b' and (resid 239 through 255 )bB239 - 255224 - 240
3535chain 'b' and (resid 274 through 298 )bB274 - 298241 - 265
3636chain 'b' and (resid 299 through 320 )bB299 - 320266 - 287
3737chain 'c' and (resid 1 through 13 )cC1 - 131 - 13
3838chain 'c' and (resid 14 through 19 )cC14 - 1914 - 19
3939chain 'c' and (resid 20 through 32 )cC20 - 3220 - 32
4040chain 'c' and (resid 33 through 50 )cC33 - 5033 - 50
4141chain 'c' and (resid 51 through 55 )cC51 - 5551 - 55
4242chain 'c' and (resid 56 through 65 )cC56 - 6556 - 65
4343chain 'c' and (resid 66 through 75 )cC66 - 7566 - 75
4444chain 'c' and (resid 76 through 95 )cC76 - 9576 - 95
4545chain 'c' and (resid 101 through 140 )cC101 - 14096 - 135
4646chain 'c' and (resid 141 through 155 )cC141 - 155136 - 150
4747chain 'c' and (resid 166 through 197 )cC166 - 197151 - 182
4848chain 'c' and (resid 198 through 215 )cC198 - 215183 - 200
4949chain 'c' and (resid 216 through 238 )cC216 - 238201 - 223
5050chain 'c' and (resid 239 through 255 )cC239 - 255224 - 240
5151chain 'c' and (resid 274 through 298 )cC274 - 298241 - 265
5252chain 'c' and (resid 299 through 320 )cC299 - 320266 - 287
5353chain 'd' and (resid 1 through 13 )dD1 - 131 - 13
5454chain 'd' and (resid 14 through 19 )dD14 - 1914 - 19
5555chain 'd' and (resid 20 through 32 )dD20 - 3220 - 32
5656chain 'd' and (resid 33 through 37 )dD33 - 3733 - 37
5757chain 'd' and (resid 38 through 50 )dD38 - 5038 - 50
5858chain 'd' and (resid 51 through 55 )dD51 - 5551 - 55
5959chain 'd' and (resid 56 through 60 )dD56 - 6056 - 60
6060chain 'd' and (resid 61 through 65 )dD61 - 6561 - 65
6161chain 'd' and (resid 66 through 75 )dD66 - 7566 - 75
6262chain 'd' and (resid 76 through 95 )dD76 - 9576 - 95
6363chain 'd' and (resid 101 through 140 )dD101 - 14096 - 135
6464chain 'd' and (resid 141 through 155 )dD141 - 155136 - 150
6565chain 'd' and (resid 166 through 181 )dD166 - 181151 - 166
6666chain 'd' and (resid 182 through 197 )dD182 - 197167 - 182
6767chain 'd' and (resid 198 through 202 )dD198 - 202183 - 187
6868chain 'd' and (resid 203 through 215 )dD203 - 215188 - 200
6969chain 'd' and (resid 216 through 225 )dD216 - 225201 - 210
7070chain 'd' and (resid 226 through 230 )dD226 - 230211 - 215
7171chain 'd' and (resid 231 through 238 )dD231 - 238216 - 223
7272chain 'd' and (resid 239 through 255 )dD239 - 255224 - 240
7373chain 'd' and (resid 274 through 298 )dD274 - 298241 - 265
7474chain 'd' and (resid 299 through 320 )dD299 - 320266 - 287
7575chain 'e' and (resid 1 through 13 )eE1 - 131 - 13
7676chain 'e' and (resid 14 through 19 )eE14 - 1914 - 19
7777chain 'e' and (resid 20 through 32 )eE20 - 3220 - 32
7878chain 'e' and (resid 33 through 37 )eE33 - 3733 - 37
7979chain 'e' and (resid 38 through 50 )eE38 - 5038 - 50
8080chain 'e' and (resid 51 through 55 )eE51 - 5551 - 55
8181chain 'e' and (resid 56 through 60 )eE56 - 6056 - 60
8282chain 'e' and (resid 61 through 65 )eE61 - 6561 - 65
8383chain 'e' and (resid 66 through 75 )eE66 - 7566 - 75
8484chain 'e' and (resid 76 through 95 )eE76 - 9576 - 95
8585chain 'e' and (resid 101 through 140 )eE101 - 14096 - 135
8686chain 'e' and (resid 141 through 155 )eE141 - 155136 - 150
8787chain 'e' and (resid 166 through 181 )eE166 - 181151 - 166
8888chain 'e' and (resid 182 through 197 )eE182 - 197167 - 182
8989chain 'e' and (resid 198 through 202 )eE198 - 202183 - 187
9090chain 'e' and (resid 203 through 215 )eE203 - 215188 - 200
9191chain 'e' and (resid 216 through 225 )eE216 - 225201 - 210
9292chain 'e' and (resid 226 through 230 )eE226 - 230211 - 215
9393chain 'e' and (resid 231 through 238 )eE231 - 238216 - 223
9494chain 'e' and (resid 239 through 255 )eE239 - 255224 - 240
9595chain 'e' and (resid 274 through 298 )eE274 - 298241 - 265
9696chain 'e' and (resid 299 through 320 )eE299 - 320266 - 287
9797chain 'f' and (resid 1 through 13 )fF1 - 131 - 13
9898chain 'f' and (resid 14 through 19 )fF14 - 1914 - 19
9999chain 'f' and (resid 20 through 32 )fF20 - 3220 - 32
100100chain 'f' and (resid 33 through 37 )fF33 - 3733 - 37
101101chain 'f' and (resid 38 through 50 )fF38 - 5038 - 50
102102chain 'f' and (resid 51 through 55 )fF51 - 5551 - 55
103103chain 'f' and (resid 56 through 60 )fF56 - 6056 - 60
104104chain 'f' and (resid 61 through 65 )fF61 - 6561 - 65
105105chain 'f' and (resid 66 through 75 )fF66 - 7566 - 75
106106chain 'f' and (resid 76 through 95 )fF76 - 9576 - 95
107107chain 'f' and (resid 101 through 140 )fF101 - 14096 - 135
108108chain 'f' and (resid 141 through 155 )fF141 - 155136 - 150
109109chain 'f' and (resid 166 through 181 )fF166 - 181151 - 166
110110chain 'f' and (resid 182 through 197 )fF182 - 197167 - 182
111111chain 'f' and (resid 198 through 202 )fF198 - 202183 - 187
112112chain 'f' and (resid 203 through 215 )fF203 - 215188 - 200
113113chain 'f' and (resid 216 through 225 )fF216 - 225201 - 210
114114chain 'f' and (resid 226 through 230 )fF226 - 230211 - 215
115115chain 'f' and (resid 231 through 238 )fF231 - 238216 - 223
116116chain 'f' and (resid 239 through 255 )fF239 - 255224 - 240
117117chain 'f' and (resid 274 through 298 )fF274 - 298241 - 265
118118chain 'f' and (resid 299 through 320 )fF299 - 320266 - 287
119119chain 'g' and (resid 1 through 13 )gG1 - 131 - 13
120120chain 'g' and (resid 14 through 19 )gG14 - 1914 - 19
121121chain 'g' and (resid 20 through 32 )gG20 - 3220 - 32
122122chain 'g' and (resid 33 through 50 )gG33 - 5033 - 50
123123chain 'g' and (resid 51 through 55 )gG51 - 5551 - 55
124124chain 'g' and (resid 56 through 60 )gG56 - 6056 - 60
125125chain 'g' and (resid 61 through 65 )gG61 - 6561 - 65
126126chain 'g' and (resid 66 through 75 )gG66 - 7566 - 75
127127chain 'g' and (resid 76 through 95 )gG76 - 9576 - 95
128128chain 'g' and (resid 101 through 140 )gG101 - 14096 - 135
129129chain 'g' and (resid 141 through 155 )gG141 - 155136 - 150
130130chain 'g' and (resid 166 through 197 )gG166 - 197151 - 182
131131chain 'g' and (resid 198 through 215 )gG198 - 215183 - 200
132132chain 'g' and (resid 216 through 238 )gG216 - 238201 - 223
133133chain 'g' and (resid 239 through 255 )gG239 - 255224 - 240
134134chain 'g' and (resid 274 through 298 )gG274 - 298241 - 265
135135chain 'g' and (resid 299 through 320 )gG299 - 320266 - 287
136136chain 'h' and (resid 1 through 13 )hH1 - 131 - 13
137137chain 'h' and (resid 14 through 19 )hH14 - 1914 - 19
138138chain 'h' and (resid 20 through 32 )hH20 - 3220 - 32
139139chain 'h' and (resid 33 through 37 )hH33 - 3733 - 37
140140chain 'h' and (resid 38 through 50 )hH38 - 5038 - 50
141141chain 'h' and (resid 51 through 55 )hH51 - 5551 - 55
142142chain 'h' and (resid 56 through 60 )hH56 - 6056 - 60
143143chain 'h' and (resid 61 through 65 )hH61 - 6561 - 65
144144chain 'h' and (resid 66 through 75 )hH66 - 7566 - 75
145145chain 'h' and (resid 76 through 95 )hH76 - 9576 - 95
146146chain 'h' and (resid 101 through 140 )hH101 - 14096 - 135
147147chain 'h' and (resid 141 through 155 )hH141 - 155136 - 150
148148chain 'h' and (resid 166 through 197 )hH166 - 197151 - 182
149149chain 'h' and (resid 198 through 215 )hH198 - 215183 - 200
150150chain 'h' and (resid 216 through 238 )hH216 - 238201 - 223
151151chain 'h' and (resid 239 through 255 )hH239 - 255224 - 240
152152chain 'h' and (resid 274 through 298 )hH274 - 298241 - 265
153153chain 'h' and (resid 299 through 320 )hH299 - 320266 - 287
154154chain 'i' and (resid 1 through 13 )iI1 - 131 - 13
155155chain 'i' and (resid 14 through 19 )iI14 - 1914 - 19
156156chain 'i' and (resid 20 through 32 )iI20 - 3220 - 32
157157chain 'i' and (resid 33 through 50 )iI33 - 5033 - 50
158158chain 'i' and (resid 51 through 55 )iI51 - 5551 - 55
159159chain 'i' and (resid 56 through 60 )iI56 - 6056 - 60
160160chain 'i' and (resid 61 through 65 )iI61 - 6561 - 65
161161chain 'i' and (resid 66 through 75 )iI66 - 7566 - 75
162162chain 'i' and (resid 76 through 95 )iI76 - 9576 - 95
163163chain 'i' and (resid 101 through 140 )iI101 - 14096 - 135
164164chain 'i' and (resid 141 through 155 )iI141 - 155136 - 150
165165chain 'i' and (resid 166 through 181 )iI166 - 181151 - 166
166166chain 'i' and (resid 182 through 197 )iI182 - 197167 - 182
167167chain 'i' and (resid 198 through 202 )iI198 - 202183 - 187
168168chain 'i' and (resid 203 through 215 )iI203 - 215188 - 200
169169chain 'i' and (resid 216 through 225 )iI216 - 225201 - 210
170170chain 'i' and (resid 226 through 230 )iI226 - 230211 - 215
171171chain 'i' and (resid 231 through 238 )iI231 - 238216 - 223
172172chain 'i' and (resid 239 through 255 )iI239 - 255224 - 240
173173chain 'i' and (resid 274 through 298 )iI274 - 298241 - 265
174174chain 'i' and (resid 299 through 320 )iI299 - 320266 - 287
175175chain 'j' and (resid 1 through 13 )jJ1 - 131 - 13
176176chain 'j' and (resid 14 through 19 )jJ14 - 1914 - 19
177177chain 'j' and (resid 20 through 32 )jJ20 - 3220 - 32
178178chain 'j' and (resid 33 through 37 )jJ33 - 3733 - 37
179179chain 'j' and (resid 38 through 50 )jJ38 - 5038 - 50
180180chain 'j' and (resid 51 through 55 )jJ51 - 5551 - 55
181181chain 'j' and (resid 56 through 60 )jJ56 - 6056 - 60
182182chain 'j' and (resid 61 through 65 )jJ61 - 6561 - 65
183183chain 'j' and (resid 66 through 75 )jJ66 - 7566 - 75
184184chain 'j' and (resid 76 through 95 )jJ76 - 9576 - 95
185185chain 'j' and (resid 101 through 140 )jJ101 - 14096 - 135
186186chain 'j' and (resid 141 through 155 )jJ141 - 155136 - 150
187187chain 'j' and (resid 166 through 197 )jJ166 - 197151 - 182
188188chain 'j' and (resid 198 through 215 )jJ198 - 215183 - 200
189189chain 'j' and (resid 216 through 238 )jJ216 - 238201 - 223
190190chain 'j' and (resid 239 through 255 )jJ239 - 255224 - 240
191191chain 'j' and (resid 274 through 298 )jJ274 - 298241 - 265
192192chain 'j' and (resid 299 through 320 )jJ299 - 320266 - 287
193193chain 'k' and (resid 1 through 13 )kK1 - 131 - 13
194194chain 'k' and (resid 14 through 19 )kK14 - 1914 - 19
195195chain 'k' and (resid 20 through 32 )kK20 - 3220 - 32
196196chain 'k' and (resid 33 through 50 )kK33 - 5033 - 50
197197chain 'k' and (resid 51 through 55 )kK51 - 5551 - 55
198198chain 'k' and (resid 56 through 60 )kK56 - 6056 - 60
199199chain 'k' and (resid 61 through 65 )kK61 - 6561 - 65
200200chain 'k' and (resid 66 through 75 )kK66 - 7566 - 75
201201chain 'k' and (resid 76 through 95 )kK76 - 9576 - 95
202202chain 'k' and (resid 101 through 140 )kK101 - 14096 - 135
203203chain 'k' and (resid 141 through 155 )kK141 - 155136 - 150
204204chain 'k' and (resid 166 through 197 )kK166 - 197151 - 182
205205chain 'k' and (resid 198 through 215 )kK198 - 215183 - 200
206206chain 'k' and (resid 216 through 238 )kK216 - 238201 - 223
207207chain 'k' and (resid 239 through 255 )kK239 - 255224 - 240
208208chain 'k' and (resid 274 through 298 )kK274 - 298241 - 265
209209chain 'k' and (resid 299 through 320 )kK299 - 320266 - 287
210210chain 'l' and (resid 1 through 13 )lL1 - 131 - 13
211211chain 'l' and (resid 14 through 19 )lL14 - 1914 - 19
212212chain 'l' and (resid 20 through 32 )lL20 - 3220 - 32
213213chain 'l' and (resid 33 through 37 )lL33 - 3733 - 37
214214chain 'l' and (resid 38 through 50 )lL38 - 5038 - 50
215215chain 'l' and (resid 51 through 55 )lL51 - 5551 - 55
216216chain 'l' and (resid 56 through 60 )lL56 - 6056 - 60
217217chain 'l' and (resid 61 through 65 )lL61 - 6561 - 65
218218chain 'l' and (resid 66 through 75 )lL66 - 7566 - 75
219219chain 'l' and (resid 76 through 95 )lL76 - 9576 - 95
220220chain 'l' and (resid 101 through 140 )lL101 - 14096 - 135
221221chain 'l' and (resid 141 through 155 )lL141 - 155136 - 150
222222chain 'l' and (resid 166 through 197 )lL166 - 197151 - 182
223223chain 'l' and (resid 198 through 215 )lL198 - 215183 - 200
224224chain 'l' and (resid 216 through 238 )lL216 - 238201 - 223
225225chain 'l' and (resid 239 through 255 )lL239 - 255224 - 240
226226chain 'l' and (resid 274 through 298 )lL274 - 298241 - 265
227227chain 'l' and (resid 299 through 320 )lL299 - 320266 - 287
228228chain 'm' and (resid 1 through 13 )mM1 - 131 - 13
229229chain 'm' and (resid 14 through 19 )mM14 - 1914 - 19
230230chain 'm' and (resid 20 through 32 )mM20 - 3220 - 32
231231chain 'm' and (resid 33 through 50 )mM33 - 5033 - 50
232232chain 'm' and (resid 51 through 55 )mM51 - 5551 - 55
233233chain 'm' and (resid 56 through 60 )mM56 - 6056 - 60
234234chain 'm' and (resid 61 through 65 )mM61 - 6561 - 65
235235chain 'm' and (resid 66 through 75 )mM66 - 7566 - 75
236236chain 'm' and (resid 76 through 95 )mM76 - 9576 - 95
237237chain 'm' and (resid 101 through 140 )mM101 - 14096 - 135
238238chain 'm' and (resid 141 through 155 )mM141 - 155136 - 150
239239chain 'm' and (resid 166 through 197 )mM166 - 197151 - 182
240240chain 'm' and (resid 198 through 215 )mM198 - 215183 - 200
241241chain 'm' and (resid 216 through 238 )mM216 - 238201 - 223
242242chain 'm' and (resid 239 through 255 )mM239 - 255224 - 240
243243chain 'm' and (resid 274 through 298 )mM274 - 298241 - 265
244244chain 'm' and (resid 299 through 320 )mM299 - 320266 - 287
245245chain 'n' and (resid 1 through 13 )nN1 - 131 - 13
246246chain 'n' and (resid 14 through 19 )nN14 - 1914 - 19
247247chain 'n' and (resid 20 through 32 )nN20 - 3220 - 32
248248chain 'n' and (resid 33 through 50 )nN33 - 5033 - 50
249249chain 'n' and (resid 51 through 55 )nN51 - 5551 - 55
250250chain 'n' and (resid 56 through 60 )nN56 - 6056 - 60
251251chain 'n' and (resid 61 through 65 )nN61 - 6561 - 65
252252chain 'n' and (resid 66 through 75 )nN66 - 7566 - 75
253253chain 'n' and (resid 76 through 95 )nN76 - 9576 - 95
254254chain 'n' and (resid 101 through 140 )nN101 - 14096 - 135
255255chain 'n' and (resid 141 through 155 )nN141 - 155136 - 150
256256chain 'n' and (resid 166 through 197 )nN166 - 197151 - 182
257257chain 'n' and (resid 198 through 215 )nN198 - 215183 - 200
258258chain 'n' and (resid 216 through 238 )nN216 - 238201 - 223
259259chain 'n' and (resid 239 through 255 )nN239 - 255224 - 240
260260chain 'n' and (resid 274 through 298 )nN274 - 298241 - 265
261261chain 'n' and (resid 299 through 320 )nN299 - 320266 - 287
262262chain 'o' and (resid 1 through 13 )oO1 - 131 - 13
263263chain 'o' and (resid 14 through 19 )oO14 - 1914 - 19
264264chain 'o' and (resid 20 through 32 )oO20 - 3220 - 32
265265chain 'o' and (resid 33 through 37 )oO33 - 3733 - 37
266266chain 'o' and (resid 38 through 50 )oO38 - 5038 - 50
267267chain 'o' and (resid 51 through 55 )oO51 - 5551 - 55
268268chain 'o' and (resid 56 through 60 )oO56 - 6056 - 60
269269chain 'o' and (resid 61 through 65 )oO61 - 6561 - 65
270270chain 'o' and (resid 66 through 75 )oO66 - 7566 - 75
271271chain 'o' and (resid 76 through 95 )oO76 - 9576 - 95
272272chain 'o' and (resid 101 through 140 )oO101 - 14096 - 135
273273chain 'o' and (resid 141 through 155 )oO141 - 155136 - 150
274274chain 'o' and (resid 166 through 197 )oO166 - 197151 - 182
275275chain 'o' and (resid 198 through 215 )oO198 - 215183 - 200
276276chain 'o' and (resid 216 through 238 )oO216 - 238201 - 223
277277chain 'o' and (resid 239 through 255 )oO239 - 255224 - 240
278278chain 'o' and (resid 274 through 298 )oO274 - 298241 - 265
279279chain 'o' and (resid 299 through 320 )oO299 - 320266 - 287
280280chain 'p' and (resid 1 through 13 )pP1 - 131 - 13
281281chain 'p' and (resid 14 through 19 )pP14 - 1914 - 19
282282chain 'p' and (resid 20 through 32 )pP20 - 3220 - 32
283283chain 'p' and (resid 33 through 37 )pP33 - 3733 - 37
284284chain 'p' and (resid 38 through 50 )pP38 - 5038 - 50
285285chain 'p' and (resid 51 through 55 )pP51 - 5551 - 55
286286chain 'p' and (resid 56 through 60 )pP56 - 6056 - 60
287287chain 'p' and (resid 61 through 65 )pP61 - 6561 - 65
288288chain 'p' and (resid 66 through 75 )pP66 - 7566 - 75
289289chain 'p' and (resid 76 through 95 )pP76 - 9576 - 95
290290chain 'p' and (resid 101 through 140 )pP101 - 14096 - 135
291291chain 'p' and (resid 141 through 155 )pP141 - 155136 - 150
292292chain 'p' and (resid 166 through 181 )pP166 - 181151 - 166
293293chain 'p' and (resid 182 through 197 )pP182 - 197167 - 182
294294chain 'p' and (resid 198 through 202 )pP198 - 202183 - 187
295295chain 'p' and (resid 203 through 215 )pP203 - 215188 - 200
296296chain 'p' and (resid 216 through 225 )pP216 - 225201 - 210
297297chain 'p' and (resid 226 through 230 )pP226 - 230211 - 215
298298chain 'p' and (resid 231 through 238 )pP231 - 238216 - 223
299299chain 'p' and (resid 239 through 255 )pP239 - 255224 - 240
300300chain 'p' and (resid 274 through 298 )pP274 - 298241 - 265
301301chain 'p' and (resid 299 through 320 )pP299 - 320266 - 287
302302chain 'q' and (resid 1 through 13 )qQ1 - 131 - 13
303303chain 'q' and (resid 14 through 19 )qQ14 - 1914 - 19
304304chain 'q' and (resid 20 through 32 )qQ20 - 3220 - 32
305305chain 'q' and (resid 33 through 50 )qQ33 - 5033 - 50
306306chain 'q' and (resid 51 through 55 )qQ51 - 5551 - 55
307307chain 'q' and (resid 56 through 60 )qQ56 - 6056 - 60
308308chain 'q' and (resid 61 through 65 )qQ61 - 6561 - 65
309309chain 'q' and (resid 66 through 75 )qQ66 - 7566 - 75
310310chain 'q' and (resid 76 through 95 )qQ76 - 9576 - 95
311311chain 'q' and (resid 101 through 140 )qQ101 - 14096 - 135
312312chain 'q' and (resid 141 through 155 )qQ141 - 155136 - 150
313313chain 'q' and (resid 166 through 197 )qQ166 - 197151 - 182
314314chain 'q' and (resid 198 through 215 )qQ198 - 215183 - 200
315315chain 'q' and (resid 216 through 238 )qQ216 - 238201 - 223
316316chain 'q' and (resid 239 through 255 )qQ239 - 255224 - 240
317317chain 'q' and (resid 274 through 298 )qQ274 - 298241 - 265
318318chain 'q' and (resid 299 through 320 )qQ299 - 320266 - 287

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