登録情報 | データベース: PDB / ID: 8ck2 |
---|
タイトル | MUC2 CysD1 G1352S |
---|
要素 | Mucin-2 |
---|
キーワード | STRUCTURAL PROTEIN / mucin / disulfide bonds / calcium |
---|
機能・相同性 | 機能・相同性情報
inner mucus layer / outer mucus layer / host-mediated regulation of intestinal microbiota composition / Defective GALNT3 causes HFTC / Defective C1GALT1C1 causes TNPS / Defective GALNT12 causes CRCS1 / Termination of O-glycan biosynthesis / O-linked glycosylation of mucins / maintenance of gastrointestinal epithelium / mucus secretion ...inner mucus layer / outer mucus layer / host-mediated regulation of intestinal microbiota composition / Defective GALNT3 causes HFTC / Defective C1GALT1C1 causes TNPS / Defective GALNT12 causes CRCS1 / Termination of O-glycan biosynthesis / O-linked glycosylation of mucins / maintenance of gastrointestinal epithelium / mucus secretion / detoxification of copper ion / cupric ion binding / Dectin-2 family / cuprous ion binding / extracellular matrix / Golgi lumen / collagen-containing extracellular matrix / extracellular space / plasma membrane類似検索 - 分子機能 : / WxxW domain / Mucin-2 protein WxxW repeating region / C8 domain / Uncharacterised domain, cysteine-rich / C8 / von Willebrand factor, type D domain / von Willebrand factor type D domain / VWFD domain profile. / von Willebrand factor (vWF) type D domain ...: / WxxW domain / Mucin-2 protein WxxW repeating region / C8 domain / Uncharacterised domain, cysteine-rich / C8 / von Willebrand factor, type D domain / von Willebrand factor type D domain / VWFD domain profile. / von Willebrand factor (vWF) type D domain / C-terminal cystine knot signature. / von Willebrand factor (vWF) type C domain / Trypsin Inhibitor-like, cysteine rich domain / Serine protease inhibitor-like superfamily / Trypsin Inhibitor like cysteine rich domain / C-terminal cystine knot domain profile. / Cystine knot, C-terminal / C-terminal cystine knot-like domain (CTCK) / VWFC domain signature. / VWFC domain profile. / von Willebrand factor (vWF) type C domain / VWFC domain類似検索 - ドメイン・相同性 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.5 Å |
---|
データ登録者 | Khmelnitsky, L. / Fass, D. |
---|
資金援助 | イスラエル, 1件 組織 | 認可番号 | 国 |
---|
Israel Science Foundation | 2660/20 | イスラエル |
|
---|
引用 | ジャーナル: To Be Published タイトル: Pulmonary Fibrosis Mutation Undermines Mucin 5B Supramolecular Assembly 著者: Khmelnitsky, L. / Javitt, G. / Reznik, N. / Yeshaya, N. / Elad, N. / Anikster, Y. / Shalva, N. / Barel, O. / Pode-Shakked, B. / Greenberg, L.J. / Segel, M.J. / Fass, D. |
---|
履歴 | 登録 | 2023年2月14日 | 登録サイト: PDBE / 処理サイト: PDBE |
---|
改定 1.0 | 2024年2月28日 | Provider: repository / タイプ: Initial release |
---|
|
---|