Entry | Database: PDB / ID: 8adt |
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Title | Rational design of a calcium-independent trypsin variant |
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Components | Serine protease 1 |
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Keywords | HYDROLASE / trypsin artificial disulfide bond enzyme engineering |
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Function / homology | Function and homology information
trypsin / serpin family protein binding / serine protease inhibitor complex / digestion / endopeptidase activity / serine-type endopeptidase activity / proteolysis / extracellular space / metal ion bindingSimilarity search - Function Serine proteases, trypsin family, histidine active site / Serine proteases, trypsin family, serine active site / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin family, histidine active site. / Serine proteases, trypsin domain profile. / Serine proteases, trypsin family, serine active site. / Trypsin-like serine protease / Serine proteases, trypsin domain / Trypsin / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clanSimilarity search - Domain/homology |
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Biological species | ![](img/tx_mammal.gif) Bos taurus (cattle) |
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Method | X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution: 1.4 Å |
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Authors | Simon, A.H. / Liebscher, S. / Kattner, A. / Kattner, C. / Bordusa, F. |
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Funding support | 1items Organization | Grant number | Country |
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Not funded | | |
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Citation | Journal: Catalysts / Year: 2022 Title: Rational Design of a Calcium-Independent Trypsin Variant Authors: Simon, A.H. / Liebscher, S. / Kattner, A. / Kattner, C. / Bordusa, F. |
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History | Deposition | Jul 11, 2022 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Sep 14, 2022 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jan 31, 2024 | Group: Data collection / Refinement description Category: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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