登録情報 データベース : PDB / ID : 7y4n 構造の表示 ダウンロードとリンクタイトル Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos 要素Growth factor receptor-bound protein 2 詳細 キーワード PEPTIDE BINDING PROTEIN / NMR spectroscopy / SH3 / Drosophila / Adapter protein機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
sevenless binding / PI3K Cascade / Downstream signal transduction / Generation of second messenger molecules / PI-3K cascade:FGFR1 / PI-3K cascade:FGFR2 / PI-3K cascade:FGFR3 / PI-3K cascade:FGFR4 / RET signaling / Erythropoietin activates RAS ... sevenless binding / PI3K Cascade / Downstream signal transduction / Generation of second messenger molecules / PI-3K cascade:FGFR1 / PI-3K cascade:FGFR2 / PI-3K cascade:FGFR3 / PI-3K cascade:FGFR4 / RET signaling / Erythropoietin activates RAS / FLT3 Signaling / Signaling by CSF3 (G-CSF) / SOS-mediated signalling / Signaling by SCF-KIT / Regulation of KIT signaling / Signalling to RAS / DAP12 signaling / SHC-related events triggered by IGF1R / Role of LAT2/NTAL/LAB on calcium mobilization / FCERI mediated Ca+2 mobilization / SHC-mediated cascade:FGFR1 / FRS-mediated FGFR1 signaling / SHC-mediated cascade:FGFR2 / FRS-mediated FGFR2 signaling / SHC-mediated cascade:FGFR3 / FRS-mediated FGFR3 signaling / FRS-mediated FGFR4 signaling / SHC-mediated cascade:FGFR4 / Signal attenuation / Insulin receptor signalling cascade / FCERI mediated MAPK activation / PIP3 activates AKT signaling / GAB1 signalosome / PI3K events in ERBB2 signaling / NCAM signaling for neurite out-growth / PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling / Antigen activates B Cell Receptor (BCR) leading to generation of second messengers / SHC1 events in ERBB4 signaling / GRB2 events in EGFR signaling / SHC1 events in EGFR signaling / GRB2 events in ERBB2 signaling / EGFR Transactivation by Gastrin / torso signaling pathway / RAF/MAP kinase cascade / tracheal outgrowth, open tracheal system / R7 cell fate commitment / Spry regulation of FGF signaling / Negative regulation of FGFR1 signaling / Negative regulation of FGFR2 signaling / Negative regulation of FGFR3 signaling / Negative regulation of FGFR4 signaling / Regulation of signaling by CBL / sevenless signaling pathway / RHOU GTPase cycle / EGFR downregulation / Cargo recognition for clathrin-mediated endocytosis / RHO GTPases Activate WASPs and WAVEs / Regulation of actin dynamics for phagocytic cup formation / epithelial cell migration, open tracheal system / follicle cell of egg chamber development / Clathrin-mediated endocytosis / imaginal disc-derived wing morphogenesis / short-term memory / olfactory learning / COP9 signalosome / epidermal growth factor receptor binding / associative learning / regulation of MAPK cascade / positive regulation of cell size / fibroblast growth factor receptor signaling pathway / vascular endothelial growth factor receptor signaling pathway / positive regulation of TORC1 signaling / phosphotyrosine residue binding / epidermal growth factor receptor signaling pathway / sensory perception of sound / positive regulation of receptor-mediated endocytosis / signaling receptor complex adaptor activity / insulin receptor signaling pathway / presynapse / Ras protein signal transduction / positive regulation of ERK1 and ERK2 cascade / signal transduction / protein-containing complex / nucleoplasm / plasma membrane / cytoplasm 類似検索 - 分子機能 Grb2-like / SH3 domain / SH2 domain / Src homology 2 (SH2) domain profile. / Src homology 2 domains / SH2 domain / Src homology 3 domains / SH2 domain superfamily / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain 類似検索 - ドメイン・相同性生物種 Drosophila melanogaster (キイロショウジョウバエ)手法 溶液NMR / molecular dynamics 詳細データ登録者 Pooppadi, M.S. / Ikeya, T. / Sugasawa, H. / Watanabe, R. / Mishima, M. / Inomata, K. / Ito, Y. 資金援助 日本, 3件 詳細 詳細を隠す組織 認可番号 国 Japan Science and Technology CREST; JPMJCR13M3 日本 Other government Tokyo Human Resources Fund for City Diplomacy Japan Society for the Promotion of Science (JSPS) JP26102538,JP19H05773 日本
引用ジャーナル : Biochem.Biophys.Res.Commun. / 年 : 2022タイトル : Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos.著者 : Sayeesh, P.M. / Ikeya, T. / Sugasawa, H. / Watanabe, R. / Mishima, M. / Inomata, K. / Ito, Y. 履歴 登録 2022年6月15日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2022年8月31日 Provider : repository / タイプ : Initial release改定 1.1 2024年5月15日 Group : Data collection / Database references / カテゴリ : chem_comp_atom / chem_comp_bond / database_2 / Item : _database_2.pdbx_DOI
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