Entry | Database: PDB / ID: 7xl5 |
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Title | Crystal structure of the H42T/A85G/I86A mutant of a nadp-dependent alcohol dehydrogenase |
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Components | NADP-dependent isopropanol dehydrogenase |
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Keywords | OXIDOREDUCTASE / dehydrogenase / mutant / Thermoanaerobacter brockii |
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Function / homology | Function and homology information
Alcohol dehydrogenase, zinc-type, conserved site / Zinc-containing alcohol dehydrogenases signature. / Alcohol dehydrogenase-like, C-terminal / Zinc-binding dehydrogenase / Alcohol dehydrogenase, N-terminal / Alcohol dehydrogenase GroES-like domain / Polyketide synthase, enoylreductase domain / Enoylreductase / GroES-like superfamily / NAD(P)-binding domain superfamilySimilarity search - Domain/homology |
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Biological species | ![](img/tx_bacteria.gif) Thermoanaerobacter brockii (bacteria) |
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Method | X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution: 2.604 Å |
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Authors | Jiang, Y.Y. / Qu, G. / Li, X. / Sun, Z.T. / Han, X. / Liu, W.D. |
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Funding support | 1items Organization | Grant number | Country |
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Not funded | | |
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Citation | Journal: Mol Catal / Year: 2022 Title: Engineering the hydrogen transfer pathway of an alcohol dehydrogenase to increase activity by rational enzyme design Authors: Jiang, Y. / Li, X. / Liu, B. / Tong, F. / Qu, G. / Sun, Z. |
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History | Deposition | Apr 21, 2022 | Deposition site: PDBJ / Processing site: PDBJ |
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Revision 1.0 | May 31, 2023 | Provider: repository / Type: Initial release |
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Revision 1.1 | Nov 29, 2023 | Group: Data collection / Refinement description Category: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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Revision 1.2 | Jun 12, 2024 | Group: Database references / Category: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.pdbx_database_id_DOI / _citation.title / _citation.year / _citation_author.name |
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