登録情報 | データベース: PDB / ID: 7vrb |
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タイトル | Structure of the Human BRG1/SS18 complex |
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要素 | SMARCA4 protein,Protein SSXT |
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キーワード | ONCOPROTEIN / four-helix bundle |
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機能・相同性 | 機能・相同性情報
npBAF complex / neuronal stem cell population maintenance / SWI/SNF complex / ephrin receptor signaling pathway / helicase activity / nuclear receptor coactivator activity / cell morphogenesis / microtubule cytoskeleton organization / microtubule cytoskeleton / chromatin organization ...npBAF complex / neuronal stem cell population maintenance / SWI/SNF complex / ephrin receptor signaling pathway / helicase activity / nuclear receptor coactivator activity / cell morphogenesis / microtubule cytoskeleton organization / microtubule cytoskeleton / chromatin organization / histone binding / intracellular signal transduction / response to xenobiotic stimulus / regulation of DNA-templated transcription / ATP hydrolysis activity / positive regulation of transcription by RNA polymerase II / ATP binding / nucleus類似検索 - 分子機能 SS18, N-terminal / SS18 family / SSXT protein (N-terminal region) / SWI/SNF complex subunit BRG1 / BRK domain / BRK domain / BRK domain superfamily / domain in transcription and CHROMO domain helicases / Glutamine-Leucine-Glutamine, QLQ / QLQ ...SS18, N-terminal / SS18 family / SSXT protein (N-terminal region) / SWI/SNF complex subunit BRG1 / BRK domain / BRK domain / BRK domain superfamily / domain in transcription and CHROMO domain helicases / Glutamine-Leucine-Glutamine, QLQ / QLQ / QLQ domain profile. / QLQ / domain in helicases and associated with SANT domains / Snf2, ATP coupling domain / Snf2-ATP coupling, chromatin remodelling complex / Snf2-ATP coupling, chromatin remodelling complex / HSA domain / Helicase/SANT-associated domain / HSA domain profile. / SNF2-like, N-terminal domain superfamily / SNF2, N-terminal / SNF2-related domain / Helicase conserved C-terminal domain / Bromodomain, conserved site / Bromodomain signature. / Bromodomain / Bromodomain profile. / bromo domain / Bromodomain / Bromodomain-like superfamily / helicase superfamily c-terminal domain / Superfamilies 1 and 2 helicase C-terminal domain profile. / Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. / DEAD-like helicases superfamily / Helicase, C-terminal / Helicase superfamily 1/2, ATP-binding domain / P-loop containing nucleoside triphosphate hydrolase類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 単波長異常分散 / 解像度: 2.389 Å |
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データ登録者 | Cheng, Y. / Chen, F. / Zhou, H. / Long, J. |
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資金援助 | 中国, 2件 組織 | 認可番号 | 国 |
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National Natural Science Foundation of China (NSFC) | 31870750 | 中国 | National Natural Science Foundation of China (NSFC) | 31670758 | 中国 |
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引用 | ジャーナル: Nat Commun / 年: 2022 タイトル: Phase transition and remodeling complex assembly are important for SS18-SSX oncogenic activity in synovial sarcomas. 著者: Cheng, Y. / Shen, Z. / Gao, Y. / Chen, F. / Xu, H. / Mo, Q. / Chu, X. / Peng, C.L. / McKenzie, T.T. / Palacios, B.E. / Hu, J. / Zhou, H. / Long, J. |
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履歴 | 登録 | 2021年10月22日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2022年5月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2022年12月7日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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改定 1.2 | 2024年5月29日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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