+Open data
-Basic information
Entry | Database: PDB / ID: 7uaj | ||||||
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Title | Crystal structure of apo HPV16 E6 | ||||||
Components | Maltose/maltodextrin-binding periplasmic protein,Protein E6 | ||||||
Keywords | VIRAL PROTEIN / Apo conformation | ||||||
Function / homology | Function and homology information symbiont-mediated suppression of host transcription / regulation of proteolysis / activation of GTPase activity / detection of maltose stimulus / maltose binding / maltose transport complex / maltose transport / maltodextrin transmembrane transport / carbohydrate transmembrane transporter activity / ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing ...symbiont-mediated suppression of host transcription / regulation of proteolysis / activation of GTPase activity / detection of maltose stimulus / maltose binding / maltose transport complex / maltose transport / maltodextrin transmembrane transport / carbohydrate transmembrane transporter activity / ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing / carbohydrate transport / ATP-binding cassette (ABC) transporter complex / cell chemotaxis / PDZ domain binding / : / outer membrane-bounded periplasmic space / symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity / symbiont-mediated perturbation of host ubiquitin-like protein modification / host cell cytoplasm / periplasmic space / DNA-templated transcription / symbiont-mediated suppression of host type I interferon-mediated signaling pathway / DNA damage response / host cell nucleus / positive regulation of transcription by RNA polymerase II / DNA binding / membrane / identical protein binding / metal ion binding Similarity search - Function | ||||||
Biological species | Escherichia coli (E. coli) Human papillomavirus type 16 | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.25 Å | ||||||
Authors | Shen, Q. / Leonard, P.G. / Cross, J.B. | ||||||
Funding support | 1items
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Citation | Journal: To Be Published Title: Disorder-to-order transition of the interdomain linker of HPV E6 upon E6AP binding reshapes p53 binding pocket Authors: Shen, Q. / Leonard, P.G. / Cross, J.B. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7uaj.cif.gz | 406.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7uaj.ent.gz | 330.9 KB | Display | PDB format |
PDBx/mmJSON format | 7uaj.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/ua/7uaj ftp://data.pdbj.org/pub/pdb/validation_reports/ua/7uaj | HTTPS FTP |
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-Related structure data
Related structure data | 4xr8S S: Starting model for refinement |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-Links
-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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