登録情報 | データベース: PDB / ID: 7qde |
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タイトル | NMR structure of Npl3 RRM12 bound to the AUCCAGUGGAA RNA |
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要素 | - Nucleolar protein 3
- RNA (5'-R(*AP*UP*CP*CP*AP*GP*UP*GP*GP*AP*A)-3')
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キーワード | RNA BINDING PROTEIN / splicing / U2snRNA / RRM / yeast / protein-RNA complex |
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機能・相同性 | 機能・相同性情報
negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled / eukaryotic initiation factor 4G binding / poly(A) binding / RNA polymerase II complex binding / translational termination / positive regulation of transcription elongation by RNA polymerase II / mRNA splicing, via spliceosome / cytoplasmic stress granule / ribosome biogenesis / negative regulation of translation ...negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled / eukaryotic initiation factor 4G binding / poly(A) binding / RNA polymerase II complex binding / translational termination / positive regulation of transcription elongation by RNA polymerase II / mRNA splicing, via spliceosome / cytoplasmic stress granule / ribosome biogenesis / negative regulation of translation / ribonucleoprotein complex / mRNA binding / identical protein binding / nucleus / cytoplasm類似検索 - 分子機能 Npl3, RNA recognition motif 1 / RNA recognition motif / RNA recognition motif / Eukaryotic RNA Recognition Motif (RRM) profile. / RNA recognition motif domain / RNA-binding domain superfamily / Nucleotide-binding alpha-beta plait domain superfamily類似検索 - ドメイン・相同性 RNA / RNA (> 10) / Serine/arginine (SR)-type shuttling mRNA binding protein NPL3類似検索 - 構成要素 |
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生物種 | Saccharomyces cerevisiae (パン酵母) synthetic construct (人工物) |
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手法 | 溶液NMR / simulated annealing |
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データ登録者 | Allain, F.H.-T. / Clery, A. / Moursy, A. |
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資金援助 | スイス, 1件 組織 | 認可番号 | 国 |
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Swiss National Science Foundation | 310030B-189379 | スイス |
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引用 | ジャーナル: Nat Commun / 年: 2023 タイトル: RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing. 著者: Moursy, A. / Clery, A. / Gerhardy, S. / Betz, K.M. / Rao, S. / Mazur, J. / Campagne, S. / Beusch, I. / Duszczyk, M.M. / Robinson, M.D. / Panse, V.G. / Allain, F.H. |
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履歴 | 登録 | 2021年11月26日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2022年12月21日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2024年1月10日 | Group: Data collection / Database references カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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