登録情報 | データベース: PDB / ID: 7p5q |
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タイトル | NMR structure of a peptide deriving from SARS-CoV-2 Lineage B.1.1.7 S RBD 482-506 fragment in HFIP/H2O |
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要素 | Spike glycoprotein |
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キーワード | ANTIVIRAL PROTEIN / SARS-CoV-2 / mimicking peptides / Spike / Receptor Binding Domain / COVID-19 / Lineage B.1.1.7 / N501Y |
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機能・相同性 | 機能・相同性情報
Maturation of spike protein / viral translation / Translation of Structural Proteins / Virion Assembly and Release / host cell surface / host extracellular space / suppression by virus of host tetherin activity / Induction of Cell-Cell Fusion / structural constituent of virion / entry receptor-mediated virion attachment to host cell ...Maturation of spike protein / viral translation / Translation of Structural Proteins / Virion Assembly and Release / host cell surface / host extracellular space / suppression by virus of host tetherin activity / Induction of Cell-Cell Fusion / structural constituent of virion / entry receptor-mediated virion attachment to host cell / host cell endoplasmic reticulum-Golgi intermediate compartment membrane / receptor-mediated endocytosis of virus by host cell / Attachment and Entry / membrane fusion / symbiont-mediated suppression of host innate immune response / positive regulation of viral entry into host cell / receptor-mediated virion attachment to host cell / receptor ligand activity / host cell surface receptor binding / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane / viral envelope / virion attachment to host cell / SARS-CoV-2 activates/modulates innate and adaptive immune responses / host cell plasma membrane / virion membrane / identical protein binding / membrane / plasma membrane類似検索 - 分子機能 Spike (S) protein S1 subunit, receptor-binding domain, SARS-CoV-2 / Spike (S) protein S1 subunit, N-terminal domain, SARS-CoV-like / Betacoronavirus spike (S) glycoprotein S1 subunit N-terminal (NTD) domain profile. / Spike glycoprotein, N-terminal domain superfamily / Betacoronavirus spike (S) glycoprotein S1 subunit C-terminal (CTD) domain profile. / Spike glycoprotein, betacoronavirus / Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus / Spike S1 subunit, receptor binding domain superfamily, betacoronavirus / Betacoronavirus spike glycoprotein S1, receptor binding / Spike glycoprotein S1, N-terminal domain, betacoronavirus-like ...Spike (S) protein S1 subunit, receptor-binding domain, SARS-CoV-2 / Spike (S) protein S1 subunit, N-terminal domain, SARS-CoV-like / Betacoronavirus spike (S) glycoprotein S1 subunit N-terminal (NTD) domain profile. / Spike glycoprotein, N-terminal domain superfamily / Betacoronavirus spike (S) glycoprotein S1 subunit C-terminal (CTD) domain profile. / Spike glycoprotein, betacoronavirus / Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus / Spike S1 subunit, receptor binding domain superfamily, betacoronavirus / Betacoronavirus spike glycoprotein S1, receptor binding / Spike glycoprotein S1, N-terminal domain, betacoronavirus-like / Betacoronavirus-like spike glycoprotein S1, N-terminal / Spike glycoprotein S2, coronavirus, heptad repeat 1 / Spike glycoprotein S2, coronavirus, heptad repeat 2 / Coronavirus spike (S) glycoprotein S2 subunit heptad repeat 2 (HR2) region profile. / Coronavirus spike (S) glycoprotein S2 subunit heptad repeat 1 (HR1) region profile. / Spike glycoprotein S2 superfamily, coronavirus / Spike glycoprotein S2, coronavirus / Coronavirus spike glycoprotein S2 / Coronavirus spike glycoprotein S1, C-terminal / Coronavirus spike glycoprotein S1, C-terminal類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_virus.gif) Severe acute respiratory syndrome coronavirus 2 (ウイルス) |
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手法 | 溶液NMR / torsion angle dynamics |
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データ登録者 | Santoro, A. / Buonocore, M. / Grimaldi, M. / D'Ursi, A.M. |
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資金援助 | 1件 |
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引用 | ジャーナル: Heliyon / 年: 2022 タイトル: Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site. 著者: Buonocore, M. / Santoro, A. / Grimaldi, M. / Covelli, V. / Firoznezhad, M. / Rodriquez, M. / Santin, M. / D'Ursi, A.M. |
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履歴 | 登録 | 2021年7月14日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2022年7月27日 | Provider: repository / タイプ: Initial release |
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改定 2.0 | 2022年10月5日 | Group: Atomic model / Author supporting evidence ...Atomic model / Author supporting evidence / Data collection / Derived calculations / Experimental preparation / Source and taxonomy / Structure summary カテゴリ: atom_site / pdbx_audit_support ...atom_site / pdbx_audit_support / pdbx_contact_author / pdbx_entity_src_syn / pdbx_nmr_ensemble / pdbx_nmr_exptl_sample / pdbx_nmr_representative / pdbx_nmr_sample_details / pdbx_nmr_software / pdbx_validate_planes / pdbx_validate_rmsd_angle / pdbx_validate_torsion / struct_conf Item: _pdbx_entity_src_syn.organism_common_name / _pdbx_nmr_ensemble.conformers_calculated_total_number ..._pdbx_entity_src_syn.organism_common_name / _pdbx_nmr_ensemble.conformers_calculated_total_number / _pdbx_nmr_ensemble.conformers_submitted_total_number / _pdbx_nmr_exptl_sample.component / _pdbx_nmr_representative.selection_criteria / _pdbx_nmr_sample_details.contents / _pdbx_nmr_sample_details.label 解説: Model orientation/position / Provider: author / タイプ: Coordinate replacement |
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改定 2.1 | 2022年11月30日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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改定 2.2 | 2022年12月7日 | Group: Database references / カテゴリ: citation / Item: _citation.page_first / _citation.page_last |
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改定 2.3 | 2023年6月14日 | Group: Other / カテゴリ: pdbx_database_status / Item: _pdbx_database_status.status_code_nmr_data |
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改定 2.4 | 2024年6月19日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 / Item: _database_2.pdbx_DOI |
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