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- PDB-7or0: Cryo-EM structure of the human TRPA1 ion channel in complex with ... -
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Basic information
Entry | Database: PDB / ID: 7or0 | |||||||||
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Title | Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60, conformation 2 | |||||||||
![]() | Transient receptor potential cation channel subfamily A member 1 | |||||||||
![]() | MEMBRANE PROTEIN / Transient receptor potential cation channel subfamily A member 1 | |||||||||
Function / homology | ![]() temperature-gated cation channel activity / stereocilium bundle / detection of chemical stimulus involved in sensory perception of pain / thermoception / TRP channels / channel activity / : / response to pain / intracellularly gated calcium channel activity / detection of mechanical stimulus involved in sensory perception of pain ...temperature-gated cation channel activity / stereocilium bundle / detection of chemical stimulus involved in sensory perception of pain / thermoception / TRP channels / channel activity / : / response to pain / intracellularly gated calcium channel activity / detection of mechanical stimulus involved in sensory perception of pain / monoatomic ion transport / sensory perception of pain / : / response to cold / calcium ion transmembrane transport / calcium channel activity / response to organic cyclic compound / intracellular calcium ion homeostasis / cellular response to hydrogen peroxide / protein homotetramerization / cell surface receptor signaling pathway / response to xenobiotic stimulus / identical protein binding / plasma membrane Similarity search - Function | |||||||||
Biological species | ![]() | |||||||||
Method | ELECTRON MICROSCOPY / single particle reconstruction / cryo EM / Resolution: 2.64 Å | |||||||||
![]() | Grieben, M. / Pike, A.C.W. / Saward, B.G. / Wang, D. / Mukhopadhyay, S.M.M. / Moreira, T. / Chalk, R. / MacLean, E.M. / Marsden, B.D. / Burgess-Brown, N.A. ...Grieben, M. / Pike, A.C.W. / Saward, B.G. / Wang, D. / Mukhopadhyay, S.M.M. / Moreira, T. / Chalk, R. / MacLean, E.M. / Marsden, B.D. / Burgess-Brown, N.A. / Bountra, C. / Schofield, C.J. / Carpenter, E.P. | |||||||||
Funding support | ![]()
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![]() | ![]() Title: Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60 Authors: Grieben, M. / Saward, B.G. / Pike, A.C.W. / Schofield, C.J. / Carpenter, E.P. | |||||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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PDBx/mmCIF format | ![]() | 481.2 KB | Display | ![]() |
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PDB format | ![]() | 370.4 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
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-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Related structure data | ![]() 13036MC ![]() 7or1C M: map data used to model this data C: citing same article ( |
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Similar structure data | Similarity search - Function & homology ![]() |
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Assembly
Deposited unit | ![]()
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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