登録情報 | データベース: PDB / ID: 7kvw |
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タイトル | Non-ribosomal didomain (holo-PCP-C) acceptor bound state |
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要素 | PCP-C didomain |
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キーワード | BIOSYNTHETIC PROTEIN / NRPS / C-domain / PCP-domain |
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機能・相同性 | 機能・相同性情報
amide biosynthetic process / amino acid activation for nonribosomal peptide biosynthetic process / secondary metabolite biosynthetic process / lipid biosynthetic process / phosphopantetheine binding / catalytic activity / cytosol類似検索 - 分子機能 Non-ribosomal peptide synthase / Condensation domain / Condensation domain / Amino acid adenylation domain / AMP-binding enzyme, C-terminal domain / AMP-binding enzyme C-terminal domain / Chloramphenicol acetyltransferase-like domain superfamily / AMP-binding, conserved site / Putative AMP-binding domain signature. / Polyketide synthase, phosphopantetheine-binding domain ...Non-ribosomal peptide synthase / Condensation domain / Condensation domain / Amino acid adenylation domain / AMP-binding enzyme, C-terminal domain / AMP-binding enzyme C-terminal domain / Chloramphenicol acetyltransferase-like domain superfamily / AMP-binding, conserved site / Putative AMP-binding domain signature. / Polyketide synthase, phosphopantetheine-binding domain / Phosphopantetheine attachment site / AMP-dependent synthetase/ligase / AMP-binding enzyme, C-terminal domain superfamily / AMP-binding enzyme / Phosphopantetheine attachment site / Phosphopantetheine attachment site. / Phosphopantetheine attachment site / ACP-like superfamily / Carrier protein (CP) domain profile. / Phosphopantetheine binding ACP domain / Alpha/Beta hydrolase fold類似検索 - ドメイン・相同性 4'-PHOSPHOPANTETHEINE / Non-ribosomal peptide synthase:Amino acid adenylation類似検索 - 構成要素 |
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生物種 | ![](img/tx_bacteria.gif) Thermobifida fusca (バクテリア) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.18 Å |
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データ登録者 | Izore, T. / Ho, Y.T.C. / Kaczmarski, J.A. / Gavriilidou, A. / Chow, K.H. / Steer, D. / Goode, R.J.A. / Schittenhelm, R.B. / Tailhades, J. / Tosin, M. ...Izore, T. / Ho, Y.T.C. / Kaczmarski, J.A. / Gavriilidou, A. / Chow, K.H. / Steer, D. / Goode, R.J.A. / Schittenhelm, R.B. / Tailhades, J. / Tosin, M. / Challis, G.L. / Krenske, E.H. / Ziemert, N. / Jackson, C.J. / Cryle, M.J. |
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資金援助 | オーストラリア, 2件 組織 | 認可番号 | 国 |
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Australian Research Council (ARC) | DP190101272 | オーストラリア | National Health and Medical Research Council (NHMRC, Australia) | APP1140619 | オーストラリア |
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引用 | ジャーナル: Nat Commun / 年: 2021 タイトル: Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. 著者: Izore, T. / Candace Ho, Y.T. / Kaczmarski, J.A. / Gavriilidou, A. / Chow, K.H. / Steer, D.L. / Goode, R.J.A. / Schittenhelm, R.B. / Tailhades, J. / Tosin, M. / Challis, G.L. / Krenske, E.H. / ...著者: Izore, T. / Candace Ho, Y.T. / Kaczmarski, J.A. / Gavriilidou, A. / Chow, K.H. / Steer, D.L. / Goode, R.J.A. / Schittenhelm, R.B. / Tailhades, J. / Tosin, M. / Challis, G.L. / Krenske, E.H. / Ziemert, N. / Jackson, C.J. / Cryle, M.J. |
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履歴 | 登録 | 2020年11月29日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2021年3月24日 | Provider: repository / タイプ: Initial release |
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改定 2.0 | 2021年4月21日 | Group: Advisory / Atomic model ...Advisory / Atomic model / Data collection / Database references / Derived calculations / Polymer sequence / Source and taxonomy / Structure summary カテゴリ: atom_site / atom_site_anisotrop ...atom_site / atom_site_anisotrop / audit_author / citation / citation_author / entity / entity_poly / entity_poly_seq / entity_src_gen / pdbx_nonpoly_scheme / pdbx_poly_seq_scheme / pdbx_unobs_or_zero_occ_residues / pdbx_validate_symm_contact / struct_conn / struct_ref / struct_ref_seq Item: _atom_site.auth_seq_id / _atom_site_anisotrop.pdbx_auth_seq_id ..._atom_site.auth_seq_id / _atom_site_anisotrop.pdbx_auth_seq_id / _audit_author.name / _citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_DOI / _citation.title / _citation.year / _citation_author.name / _entity.formula_weight / _entity_poly.pdbx_seq_one_letter_code / _entity_poly.pdbx_seq_one_letter_code_can / _entity_src_gen.pdbx_end_seq_num / _pdbx_nonpoly_scheme.pdb_seq_num / _pdbx_validate_symm_contact.auth_seq_id_2 / _struct_conn.ptnr2_auth_seq_id / _struct_ref.pdbx_seq_one_letter_code / _struct_ref_seq.db_align_end / _struct_ref_seq.pdbx_auth_seq_align_end / _struct_ref_seq.seq_align_end |
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改定 2.1 | 2021年5月19日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title / _citation_author.identifier_ORCID / _citation_author.name |
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改定 2.2 | 2024年4月3日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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