登録情報 | データベース: PDB / ID: 7fxa |
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タイトル | Crystal Structure of human FABP4 in complex with 6-bromo-4-hexyl-2-oxo-1,3-dihydroquinoline-4-carboxylic acid |
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要素 | Fatty acid-binding protein, adipocyte |
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キーワード | LIPID BINDING PROTEIN / FATTY ACID BINDING PROTEIN / CYTOPLASM / LIPID-BINDING / TRANSPORT / PROTEIN BINDING |
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機能・相同性 | 機能・相同性情報
hormone receptor binding / white fat cell differentiation / long-chain fatty acid transmembrane transporter activity / cellular response to lithium ion / long-chain fatty acid binding / long-chain fatty acid transport / Triglyceride catabolism / fatty acid transport / brown fat cell differentiation / lipid droplet ...hormone receptor binding / white fat cell differentiation / long-chain fatty acid transmembrane transporter activity / cellular response to lithium ion / long-chain fatty acid binding / long-chain fatty acid transport / Triglyceride catabolism / fatty acid transport / brown fat cell differentiation / lipid droplet / cholesterol homeostasis / fatty acid binding / response to bacterium / Transcriptional regulation of white adipocyte differentiation / positive regulation of inflammatory response / cellular response to tumor necrosis factor / positive regulation of cold-induced thermogenesis / negative regulation of DNA-templated transcription / extracellular exosome / nucleus / cytoplasm / cytosol類似検索 - 分子機能 Cytosolic fatty-acid binding proteins signature. / Intracellular lipid binding protein / Cytosolic fatty-acid binding / Lipocalin / cytosolic fatty-acid binding protein family / Lipocalin/cytosolic fatty-acid binding domain / Calycin類似検索 - ドメイン・相同性 Chem-QYP / Fatty acid-binding protein, adipocyte類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.12 Å |
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データ登録者 | Ehler, A. / Benz, J. / Obst, U. / Hofheinz, W. / Rudolph, M.G. |
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資金援助 | スイス, 1件 組織 | 認可番号 | 国 |
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F. Hoffmann-La Roche LTD | | スイス |
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引用 | ジャーナル: To be published タイトル: Crystal Structure of a human FABP4 complex 著者: Obst, U. / Magnone, C. / Kuhn, B. / Rudolph, M.G. |
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履歴 | 登録 | 2023年4月27日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2023年6月14日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2024年4月3日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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