登録情報 | データベース: PDB / ID: 7fat |
---|
タイトル | Structure Determination of the RBD-NB1A7 |
---|
要素 | |
---|
キーワード | STRUCTURAL PROTEIN / SARS-CoV-2 / RBD / nanobody |
---|
機能・相同性 | 機能・相同性情報
Maturation of spike protein / viral translation / Translation of Structural Proteins / Virion Assembly and Release / host cell surface / host extracellular space / suppression by virus of host tetherin activity / Induction of Cell-Cell Fusion / structural constituent of virion / entry receptor-mediated virion attachment to host cell ...Maturation of spike protein / viral translation / Translation of Structural Proteins / Virion Assembly and Release / host cell surface / host extracellular space / suppression by virus of host tetherin activity / Induction of Cell-Cell Fusion / structural constituent of virion / entry receptor-mediated virion attachment to host cell / host cell endoplasmic reticulum-Golgi intermediate compartment membrane / receptor-mediated endocytosis of virus by host cell / Attachment and Entry / membrane fusion / positive regulation of viral entry into host cell / receptor-mediated virion attachment to host cell / receptor ligand activity / host cell surface receptor binding / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane / viral envelope / virion attachment to host cell / SARS-CoV-2 activates/modulates innate and adaptive immune responses / host cell plasma membrane / virion membrane / identical protein binding / membrane / plasma membrane類似検索 - 分子機能 Spike (S) protein S1 subunit, receptor-binding domain, SARS-CoV-2 / Spike (S) protein S1 subunit, N-terminal domain, SARS-CoV-like / Betacoronavirus spike (S) glycoprotein S1 subunit N-terminal (NTD) domain profile. / Spike glycoprotein, N-terminal domain superfamily / Betacoronavirus spike (S) glycoprotein S1 subunit C-terminal (CTD) domain profile. / Spike glycoprotein, betacoronavirus / Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus / Spike S1 subunit, receptor binding domain superfamily, betacoronavirus / Betacoronavirus spike glycoprotein S1, receptor binding / Spike glycoprotein S1, N-terminal domain, betacoronavirus-like ...Spike (S) protein S1 subunit, receptor-binding domain, SARS-CoV-2 / Spike (S) protein S1 subunit, N-terminal domain, SARS-CoV-like / Betacoronavirus spike (S) glycoprotein S1 subunit N-terminal (NTD) domain profile. / Spike glycoprotein, N-terminal domain superfamily / Betacoronavirus spike (S) glycoprotein S1 subunit C-terminal (CTD) domain profile. / Spike glycoprotein, betacoronavirus / Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus / Spike S1 subunit, receptor binding domain superfamily, betacoronavirus / Betacoronavirus spike glycoprotein S1, receptor binding / Spike glycoprotein S1, N-terminal domain, betacoronavirus-like / Betacoronavirus-like spike glycoprotein S1, N-terminal / Spike glycoprotein S2, coronavirus, heptad repeat 1 / Spike glycoprotein S2, coronavirus, heptad repeat 2 / Coronavirus spike (S) glycoprotein S2 subunit heptad repeat 2 (HR2) region profile. / Coronavirus spike (S) glycoprotein S2 subunit heptad repeat 1 (HR1) region profile. / Spike glycoprotein S2 superfamily, coronavirus / Spike glycoprotein S2, coronavirus / Coronavirus spike glycoprotein S2 / Coronavirus spike glycoprotein S1, C-terminal / Coronavirus spike glycoprotein S1, C-terminal類似検索 - ドメイン・相同性 |
---|
生物種 | ![](img/tx_virus.gif) Severe acute respiratory syndrome coronavirus 2 (ウイルス)
![](img/tx_mammal.gif) Camelus bactrianus (フタコブラクダ) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.99 Å |
---|
データ登録者 | Geng, Y. / Shi, Z.Z. / Li, X.Y. / Wang, L. / Sun, Z.C. / Zhang, H.W. / Chen, X.C. |
---|
資金援助 | 中国, 1件 組織 | 認可番号 | 国 |
---|
National Natural Science Foundation of China (NSFC) | 31670743 | 中国 |
|
---|
引用 | ジャーナル: Structure / 年: 2022 タイトル: Structural basis of nanobodies neutralizing SARS-CoV-2 variants 著者: Shi, Z. / Li, X. / Wang, L. / Sun, Z. / Zhang, H. / Chen, X. / Cui, Q. / Qiao, H. / Lan, Z. / Zhang, X. / Li, X. / Li, L. / Xu, J. / Gong, R. / Fan, C. / Geng, Y. |
---|
履歴 | 登録 | 2021年7月7日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
---|
改定 1.0 | 2022年5月18日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2023年11月29日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
---|
|
---|