Entry | Database: PDB / ID: 7eqc |
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Title | Crystal structure of the mini-centralspindlin complex |
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Components | - CYtoKinesis defect
- Kinesin-like protein
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Keywords | CELL CYCLE / Heterotetramer / Centralspindlin complex / assembly / molecular backbone |
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Function / homology | Function and homology information
spindle midzone assembly / : / CDC42 GTPase cycle / RHOD GTPase cycle / RAC1 GTPase cycle / pronuclear migration / COPI-dependent Golgi-to-ER retrograde traffic / Kinesins / RHOA GTPase cycle / RHOB GTPase cycle ...spindle midzone assembly / : / CDC42 GTPase cycle / RHOD GTPase cycle / RAC1 GTPase cycle / pronuclear migration / COPI-dependent Golgi-to-ER retrograde traffic / Kinesins / RHOA GTPase cycle / RHOB GTPase cycle / microtubule bundle formation involved in mitotic spindle midzone assembly / regulation of actomyosin contractile ring contraction / centralspindlin complex / meiotic spindle midzone assembly / polar body extrusion after meiotic divisions / mitotic cleavage furrow ingression / mitotic spindle midzone assembly / mitotic spindle midzone / plus-end-directed microtubule motor activity / microtubule motor activity / kinesin complex / microtubule-based movement / mitotic sister chromatid segregation / cleavage furrow / mitotic cytokinesis / spindle midzone / GTPase activator activity / positive regulation of GTPase activity / spindle / midbody / microtubule binding / microtubule / intracellular signal transduction / centrosome / protein kinase binding / ATP hydrolysis activity / ATP binding / identical protein binding / nucleus / plasma membrane / cytoplasmSimilarity search - Function Kinesin-like protein Kif23, Arf6-interacting domain / Kinesin-like protein Kif23, Arf6-interacting domain superfamily / Arf6-interacting domain of mitotic kinesin-like protein 1 / Kinesin-like protein / Rho GTPase-activating protein domain / RhoGAP domain / Rho GTPase-activating proteins domain profile. / GTPase-activator protein for Rho-like GTPases / Phorbol esters/diacylglycerol binding domain (C1 domain) / Rho GTPase activation protein ...Kinesin-like protein Kif23, Arf6-interacting domain / Kinesin-like protein Kif23, Arf6-interacting domain superfamily / Arf6-interacting domain of mitotic kinesin-like protein 1 / Kinesin-like protein / Rho GTPase-activating protein domain / RhoGAP domain / Rho GTPase-activating proteins domain profile. / GTPase-activator protein for Rho-like GTPases / Phorbol esters/diacylglycerol binding domain (C1 domain) / Rho GTPase activation protein / Kinesin motor domain signature. / Kinesin motor domain, conserved site / Kinesin motor domain / Kinesin motor domain profile. / Kinesin motor, catalytic domain. ATPase. / Kinesin motor domain / Zinc finger phorbol-ester/DAG-type signature. / Zinc finger phorbol-ester/DAG-type profile. / Protein kinase C-like, phorbol ester/diacylglycerol-binding domain / Kinesin motor domain superfamily / P-loop containing nucleoside triphosphate hydrolaseSimilarity search - Domain/homology |
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Biological species | ![](img/tx_invertebrata.gif) Caenorhabditis elegans (invertebrata) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / SIRAS / Resolution: 2.5 Å |
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Authors | Chen, Z. / Pan, H. |
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Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 2021 Title: Mechanistic insights into central spindle assembly mediated by the centralspindlin complex. Authors: Pan, H. / Guan, R. / Zhao, R. / Ou, G. / Chen, Z. |
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History | Deposition | May 1, 2021 | Deposition site: PDBJ / Processing site: PDBJ |
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Revision 1.0 | Apr 13, 2022 | Provider: repository / Type: Initial release |
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Revision 1.1 | May 29, 2024 | Group: Data collection / Refinement description Category: chem_comp_atom / chem_comp_bond / struct_ncs_dom_lim Item: _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id ..._struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id |
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