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Yorodumi- PDB-7ald: Antimicrobial peptide Capitellacin from polychaeta Capitella teleta -
+Open data
-Basic information
Entry | Database: PDB / ID: 7ald | |||||||||
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Title | Antimicrobial peptide Capitellacin from polychaeta Capitella teleta | |||||||||
Components | BRICHOS domain-containing protein | |||||||||
Keywords | ANTIMICROBIAL PROTEIN / Antimicrobial peptides | |||||||||
Function / homology | BRICHOS domain / BRICHOS domain profile. / membrane / BRICHOS domain-containing protein Function and homology information | |||||||||
Biological species | Capitella teleta (invertebrata) | |||||||||
Method | SOLUTION NMR / torsion angle dynamics | |||||||||
Authors | Tsarev, A.V. / Reznikova, O.V. / Shenkarev, Z.O. | |||||||||
Funding support | Russian Federation, 2items
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Citation | Journal: Mar Drugs / Year: 2020 Title: Structure Elucidation and Functional Studies of a Novel beta-hairpin Antimicrobial Peptide from the Marine Polychaeta Capitella teleta . Authors: Panteleev, P.V. / Tsarev, A.V. / Safronova, V.N. / Reznikova, O.V. / Bolosov, I.A. / Sychev, S.V. / Shenkarev, Z.O. / Ovchinnikova, T.V. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7ald.cif.gz | 113.1 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7ald.ent.gz | 78.5 KB | Display | PDB format |
PDBx/mmJSON format | 7ald.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7ald_validation.pdf.gz | 427.7 KB | Display | wwPDB validaton report |
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Full document | 7ald_full_validation.pdf.gz | 531.2 KB | Display | |
Data in XML | 7ald_validation.xml.gz | 14.7 KB | Display | |
Data in CIF | 7ald_validation.cif.gz | 17.3 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/al/7ald ftp://data.pdbj.org/pub/pdb/validation_reports/al/7ald | HTTPS FTP |
-Related structure data
Similar structure data | |
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Other databases |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein/peptide | Mass: 2388.888 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Capitella teleta (invertebrata) / Gene: CAPTEDRAFT_185237 / Plasmid: pET-His8-Trx-CT / Details (production host): pET-20b based vector / Production host: Escherichia coli BL21(DE3) (bacteria) / References: UniProt: R7TSD6 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||
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NMR experiment |
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-Sample preparation
Details | Type: solution / Contents: 1.5 mM Capitellacin, 95% H2O/5% D2O / Label: Sample / Solvent system: 95% H2O/5% D2O |
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Sample | Conc.: 1.5 mM / Component: Capitellacin / Isotopic labeling: natural abundance |
Sample conditions | Ionic strength: 0.1 mM / Label: conditions_1 / pH: 5.2 / Pressure: AMBIENT atm / Temperature: 303 K |
-NMR measurement
NMR spectrometer |
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-Processing
NMR software |
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Refinement | Method: torsion angle dynamics / Software ordinal: 1 | ||||||||||||||||||||||||
NMR representative | Selection criteria: target function | ||||||||||||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the least restraint violations Conformers calculated total number: 200 / Conformers submitted total number: 20 |